The glucagon like peptide 1 analogue, exendin-4, attenuates oxidative stress-induced retinal cell death in early diabetic rats through promoting Sirt1 and Sirt3 expression

Experimental Eye Research

Volumn 151, Issue , 2016, Pages 203-211

  Zeng, Ying ^a   Yang, Ke ^a,b   Wang, Fang ^a   Zhou, Liping ^a   Hu, Yong ^a   Tang, Meiling ^a   Zhang, Shijia ^a   Jin, Shuqing ^a   Zhang, Jingfa ^a   Wang, Juan ^a   Li, Weiye ^c   Lu, Lixia ^a   Xu, Guo Tong ^a,d  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d TONGJI UNIVERSITY   (China)

Author keywords

Cell death; Diabetic retinopathy; Exendin 4; Oxidative stress; Sirtuin

Indexed keywords

BETA ACTIN; EXENDIN 4; HYDROGEN PEROXIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6; SIRTUIN 7; ANTIDIABETIC AGENT; GLUCAGON LIKE PEPTIDE 1; PEPTIDE; SIRT-3 PROTEIN, RAT; SIRT1 PROTEIN, RAT; SIRTUIN; VENOM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DENSITOMETRY; DOWN REGULATION; DRUG ACTIVITY; ELECTRORETINOGRAM; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA; RETINA CELL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TUNEL ASSAY; UPREGULATION; VISION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DIABETIC RETINOPATHY; DRUG EFFECTS; ELECTRORETINOGRAPHY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RETINA GANGLION CELL; SPRAGUE DAWLEY RAT; TIME FACTOR;

ANIMALS; CELL DEATH; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; HYPOGLYCEMIC AGENTS; IMMUNOBLOTTING; IN SITU NICK-END LABELING; MALE; OXIDATIVE STRESS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL GANGLION CELLS; RNA, MESSENGER; SIRTUIN 1; SIRTUINS; TIME FACTORS; VENOMS;

EID: 84989952584     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2016.05.002     Document Type: Article

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42. th Congress of Chinese Ophthalmological Society, 2013 Poster PO-0259.
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