MiR-195 regulates SIRT1-mediated changes in diabetic retinopathy

Diabetologia

Volumn 57, Issue 5, 2014, Pages 1037-1046

  Mortuza, Rokhsana ^a   Feng, Biao ^a   Chakrabarti, Subrata ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Diabetic retinopathy; Endothelial cell; miR 195; SIRT1

Indexed keywords

ANTAGOMIR; FIBRONECTIN; GLUCOSE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MICRORNA; MICRORNA 195; SIRTUIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN; 3' UNTRANSLATED REGION; MIRN195 MICRORNA, HUMAN; MIRN195 MICRORNA, RAT; SIRT1 PROTEIN, HUMAN; SIRT1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSFECTION; HYPERGLYCEMIA; MALE; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WESTERN BLOTTING; 3' UNTRANSLATED REGION; ADENOVIRIDAE; ANIMAL; CELL LINE; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MICROCIRCULATION; RETINA; SKIN; SPRAGUE DAWLEY RAT;

3' UNTRANSLATED REGIONS; ADENOVIRIDAE; ANIMALS; CELL LINE; DIABETES MELLITUS; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; FIBRONECTINS; HEK293 CELLS; HUMANS; HYPERGLYCEMIA; MALE; MICROCIRCULATION; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY; RETINA; SIRTUIN 1; SKIN;

EID: 84898599871     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3197-9     Document Type: Article

References (50)

1. Khan ZA, Chakrabarti S (2003) Growth factors in proliferative diabetic retinopathy. Exp Diabesity Res 4:287-301 (Pubitemid 38035568)
2. Antonetti DA, Klein R, Gardner TW (2012) Diabetic retinopathy. N Engl J Med 366:1227-1239
3. Mohamed Q, Gillies MC, Wong TY (2007) Management of diabetic retinopathy: a systematic review. JAMA 298:902-916 (Pubitemid 47311296)
4. Rother KI (2007) Diabetes treatment - bridging the divide. N Engl J Med 356:1499-1501 (Pubitemid 46588414)
5. Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820 (Pubitemid 34000785)
6. Joussen AM, Poulaki V, Le ML et al (2004) A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 18:1450-1452 (Pubitemid 39561611)
7. Chen S, Mukherjee S, Chakraborty C, Chakrabarti S (2003) High glucose-induced endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1. Am J Physiol Cell Physiol 284:263-272
8. Chen S, Khan ZA, Cukiernik M, Chakrabarti S (2003) Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications. Am J Physiol Endocrinol Metab 284:1089-1097
9. Kaur H, Chen S, Xin X et al (2006) Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes 55:3104-3111 (Pubitemid 44923649)
10. Chen S, Feng B, George B et al (2010) Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells. Am J Physiol Endocrinol Metab 298:127-137
11. Chiu J, Khan ZA, Farhangkhoee H, Chakrabarti S (2009) Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB. Nutrition 25:964-972
12. Xin X, Khan ZA, Chen S, Chakrabarti S (2004) Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis. Lab Investig 84:1451-1459 (Pubitemid 39482162)
13. Roy S, Cagliero E, Lorenzi M (1996) Fibronectin overexpression in retinal microvessels of patients with diabetes. Invest Ophthalmol Vis Sci 37:258-266 (Pubitemid 26057051)
14. Khan ZA, Chan BM, Uniyal S et al (2005) EDB fibronectin and angiogenesis - a novel mechanistic pathway. Angiogenesis 8:183-196 (Pubitemid 41759143)
15. Kumazaki T, Kobayashi M, Mitsui Y (1993) Enhanced expression of fibronectin during in vivo cellular aging of human vascular endothelial cells and skin fibroblasts. Exp Cell Res 205:396-402 (Pubitemid 23192148)
16. Gama MA, Gasperi RD, Rocher AB et al (2010) Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations. Am J Pathol 176:353-368
17. Sataranatarajan K, Feliers D, Mariappan MM et al (2012) Molecular events in matrix protein metabolism in the aging kidney. Aging Cell 11:1065-1073
18. Gerrits PO, Weerd H, Want JJ et al (2010) Microvascular changes in estrogen-α sensitive brainstem structures of aging female hamsters. Neurosci Res 67:267-274
19. Sangaralingham SJ, Heublein DM, Grande JP et al (2011) Urinary C-type natriuretic peptide excretion: a potential novel biomarker for renal fibrosis during aging. Am J Physiol Ren Physiol 301:943-952
20. Jaliffa C, Ameqrane I, Dansault A et al (2009) Sirt1 involvement in rd10 mouse retinal degeneration. Invest Ophthalmol Vis Sci 50:3562-3572
21. Brooks CL, Gu W (2009) Opinion: how does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 9:123-128
22. Rahman S, Islam R (2011) Mammalian Sirt1: insights on its biological functions. Cell Commun Signal 9:11
23. Kubota S, Kurihara T, Ebinuma M et al (2012) Resveratrol prevents light-induced retinal degeneration via suppressing activator protein-1 activation. Am J Pathol 177:1725-1731
24. Peng CH, Cherng JY, Chiou GY et al (2011) Delivery of Oct4 and SirT1 with cationic polyurethanes-short branch PEI to aged retinal pigment epithelium. Biomaterials 32:9077-9088
25. Yamakuchi M (2012) MicroRNA regulation of SIRT1. Front Physiol 3:68
26. Mortuza R, Chen S, Feng B, Sen S, Chakrabarti S (2013) High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway. PLoS One 8:e54514
27. Chuang JC, Jones PA (2007) Epigenetics and microRNAs. Pediatr Res 61:24-29 (Pubitemid 46653064)
28. Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233
29. Ørom UA, Lund AH (2010) Experimental identification of microRNA targets. Gene 451:1-5
30. Villeneuve LM, Natarajan R (2010) The role of epigenetics in the pathology of diabetic complications. Am J Physiol Ren Physiol 299:14-25
31. Lorenzen J, Kumarswamy R, Dangwal S, Thum T (2012) MicroRNAs in diabetes and diabetes-associated complications. RNA Biol 9:820-827
32. Wu JH, Gao Y, Ren AJ et al (2012) Altered microRNA expression profiles in retinas with diabetic retinopathy. Ophthalmic Res 47:195-201
33. Kantharidis P, Wang B, Carew RM, Lan HY (2011) Diabetes complications: the microRNA perspective. Diabetes 60:1832-1837
34. Kovacs B, Lumayag S, Cowan C, Xu S (2011) MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats. Invest Ophthalmol Vis Sci 52:4402-4409
35. Natarajan R, Putta S, Kato M (2012) MicroRNAs and diabetic complications. J Cardiovasc Transl Res 5:413-422
36. Karolina DS, Tavintharan S, Armugam A et al (2012) Circulating miRNA profiles in patients with metabolic syndrome. J Clin Endocrinol Metab 97:2271-2276
37. Chen YQ, Wang XX, Yao XM et al (2011) MicroRNA-195 promotes apoptosis in mouse podocytes via enhanced caspase activity driven by BCL2 insufficiency. Am J Nephrol 34:549-559
38. Herrera BM, Lockstone HE, Taylor JM et al (2010) Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 53:1099-1109
39. Zhu H, Yang Y, Wang Y et al (2011) MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1. Cardiovasc Res 92:75-84
40. Bolmeson C, Esguerra JL, Salehi A et al (2011) Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects. Biochem Biophys Res Commun 404:16-22
41. He JF, Luo YM, Wan XH, Jiang D (2011) Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis. J Biochem Mol Toxicol 25:404-408
42. McArthur K, Feng B, Wu Y, Chen S, Chakrabarti S (2011) MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathy. Diabetes 60:1314-1323
43. Feng B, Chen S, McArthur K et al (2011) miR-146a-mediated extracellular matrix protein production in chronic diabetes complications. Diabetes 60:2975-2984
44. Wu Y, Feng B, Chen S, Chakrabarti S (2012) ERK5 regulates glucose-induced increased fibronectin production in the endothelial cells and in the retina in diabetes. Invest Ophthalmol Vis Sci 53:8405-8413
45. Turchinovich A, Zoidl, Dermietzel R (2010) Non viral siRNA delivery into the mouse retina in vivo. BMC Ophthalmol 10:25
46. Wang M, Tan LP, Dijkstra MK et al (2008) miRNA analysis in B cell chronic lymphocytic leukaemia: proliferation centres characterized by low miR-150 and high BIC/miR-155 expression. J Pathol 215:13-20 (Pubitemid 351619871)
47. Mimura T, Joyce NC (2006) Replication competence and senescence in central and peripheral human corneal endothelium. Invest Ophthalmol Vis Sci 47:1387-1396 (Pubitemid 46780745)
48. Jan K, Satoru K, Ravi B et al (2007) Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res 35:2885-2892 (Pubitemid 47073627)
49. Giacco F, Brownlee M (2010) Oxidative stress and diabetic complications. Circ Res 107:1058-1070
50. Wang R, Zhao N, Li S et al (2013) MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42. Hepatology 58:642-653