The ATG16L1-T300A allele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

Gut

Volumn 64, Issue 10, 2015, Pages 1546-1552

  Sadabad, Mehdi Sadaghian ^a   Regeling, Anouk ^a   De Goffau, Marcus C ^a   Blokzijl, Tjasso ^a   Weersma, Rinse K ^a   Penders, John ^b   Faber, Klaas Nico ^a   Harmsen, Hermie J M ^a   Dijkstra, Gerard ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ATG16L1 PROTEIN, HUMAN; CARRIER PROTEIN;

ARTICLE; ATG16L1 GENE; AUTOPHAGY; BACTERIAL CLEARANCE; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; BACTEROIDACEAE; COLONY FORMING UNIT; CONTROLLED STUDY; CROHN DISEASE; DNA EXTRACTION; DNA POLYMORPHISM; ENTEROBACTERIACEAE; ENVIRONMENTAL FACTOR; ESCHERICHIA COLI; FUSOBACTERIACEAE; GENE; GENETIC RISK; GENETIC VARIABILITY; HEREDITY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; ILEUM MUCOSA; INNATE IMMUNITY; INTESTINE BIOPSY; INTESTINE FLORA; LACHNOSPIRACEAE; MICROORGANISM; MONOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PYROSEQUENCING; SYMBIONT; ALLELE; BIOPSY; FEMALE; GENETICS; HOMOZYGOTE; ILEUM; INTESTINE MUCOSA; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; AUTOPHAGY; BIOPSY; CARRIER PROTEINS; CROHN DISEASE; DNA; FEMALE; HOMOZYGOTE; HUMANS; ILEUM; INTESTINAL MUCOSA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84941344904     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2014-307289     Document Type: Article

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