Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans

Aging Cell

Volumn 16, Issue 1, 2017, Pages 104-112

  Desjardins, David ^a   Cacho Valadez, Briseida ^a   Liu, Ju Ling ^a   Wang, Ying ^a   Yee, Callista ^a   Bernard, Kristine ^a   Khaki, Arman ^a   Breton, Lionel ^b   Hekimi, Siegfried ^a  

^a MCGILL UNIVERSITY   (Canada)

^b L'Oréal Research Center   (France)

Author keywords

aging; antioxidants; C. elegans; prooxidants; reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ASCORBIC ACID; PARAQUAT; REACTIVE OXYGEN METABOLITE; RESVERATROL; SUPEROXIDE DISMUTASE; ANTIOXIDANT; STILBENE DERIVATIVE;

AGED; AGING; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CAENORHABDITIS ELEGANS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG UPTAKE; ENZYME ACTIVITY; GAS 1 GENE; GENE; GENE MUTATION; GENOTYPE; LIFE EXTENSION; METABOLISM; MITOCHONDRION; MUTANT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; GENETICS; LONGEVITY; MUTATION; PHYSIOLOGY;

ACETYLCYSTEINE; AGING; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CAENORHABDITIS ELEGANS; LONGEVITY; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION; OXIDATIVE STRESS; PARAQUAT; REACTIVE OXYGEN SPECIES; STILBENES; SUPEROXIDE DISMUTASE;

EID: 84989360846     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12528     Document Type: Article

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