Detoxifying enzymes at the cross-roads of inflammation, oxidative stress, and drug hypersensitivity: Role of glutathione transferase P1-1 and aldose reductase

Frontiers in Pharmacology

Volumn 7, Issue AUG, 2016, Pages

  Sánchez Gómez, Francisco J ^a   Díez Dacal, Beatriz ^a   García Martín, Elena ^b   Agúndez, José A G ^b   Pajares, María A ^c   Pérez Sala, Dolores ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITY OF EXTREMADURA   (Spain)

^c CSIC   (Spain)

Author keywords

Aldose reductase; Allergy; Detoxification; Drug adduct; Drug hypersensitivity; Glutathione transferase; Inflammation; Oxidative stress

Indexed keywords

ALDEHYDE REDUCTASE; ALDEHYDE REDUCTASE 1B1; AUTACOID; CISPLATIN; DAUNORUBICIN; DOXORUBICIN; GLUTATHIONE TRANSFERASE P1; LODOXAMIDE TROMETAMOL; SORBINIL; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ARTICLE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; EPIGENETICS; GENETIC POLYMORPHISM; HAPTEN CARRIER COMPLEX; HUMAN; HYPERSENSITIVITY; INFLAMMATION; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; REDOX STRESS; SIGNAL TRANSDUCTION;

EID: 84988735048     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2016.00237     Document Type: Article

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