Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 3, 2011, Pages 539-548

  Schroer, Kathy T ^a   Gibson, Aaron M ^a   Sivaprasad, Umasundari ^a   Bass, Stacey A ^a   Ericksen, Mark B ^a   Wills Karp, Marsha ^a   Lecras, Tim ^a   Fitzpatrick, Anne M ^b   Brown, Lou Ann S ^b   Stringer, Keith F ^a   Hershey, Gurjit K Khurana ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

asthma; gene; Glutathione S transferase pi; oxidative stress; redox homeostasis

Indexed keywords

ALLERGEN; CYSTEINE; GLUTATHIONE TRANSFERASE P1; INTERLEUKIN 13; TRANSCRIPTION FACTOR NRF2;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CHILD; CONTROLLED STUDY; DOWN REGULATION; HOMEOSTASIS; HUMAN; LUNG; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHOOL CHILD; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WILD TYPE;

ADOLESCENT; ALLERGENS; ANIMALS; ASTHMA; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; GLUTATHIONE S-TRANSFERASE PI; HOMEOSTASIS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SKIN TESTS;

EID: 80052265103     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.04.018     Document Type: Article

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