The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells

Nature Immunology

Volumn 17, Issue 11, 2016, Pages 1312-1321

  King, Bryan ^a,b,c   Boccalatte, Francesco ^a,b   Moran Crusio, Kelly ^a,b,d   Wolf, Elmar ^e   Wang, Jingjing ^a,b   Kayembe, Clarisse ^a,b   Lazaris, Charalampos ^a,b   Yu, Xiaofeng ^a,b   Aranda Orgilles, Beatriz ^a,b   Lasorella, Anna ^f   Aifantis, Iannis ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d New York   (United States)

^e UNIVERSITY OF WÜRZBURG   (Germany)

^f Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; FLUOROURACIL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; PROTEIN C MYB; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE HUWE1; UNCLASSIFIED DRUG; VINCULIN; HUWE1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW STROMA CELL; CELL FATE; CELL FUNCTION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; HEMATOPOIETIC STEM CELL; LYMPHOID PROGENITOR CELL; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROCESSING; STEM CELL SELF-RENEWAL; ANIMAL; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL SELF-RENEWAL; CLUSTER ANALYSIS; CYTOLOGY; DEFICIENCY; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENETICS; KNOCKOUT MOUSE; LYMPHOCYTE; METABOLISM; ONCOGENE MYC; PHYSIOLOGICAL STRESS; PROTEIN STABILITY; TRANSGENIC MOUSE;

ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL SELF RENEWAL; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENES, MYC; HEMATOPOIETIC STEM CELLS; LYMPHOCYTES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-MYC; STRESS, PHYSIOLOGICAL; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES;

EID: 84988695241     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3559     Document Type: Article

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