The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain

Developmental Cell

Volumn 17, Issue 2, 2009, Pages 210-221

  Zhao, Xudong ^a   D' Arca, Domenico ^a   Lim, Wei Keat ^a   Brahmachary, Manisha ^a   Carro, Maria Stella ^a   Ludwig, Thomas ^a   Cardo, Carlos Cordon ^a   Guillemot, Francois ^b   Aldape, Ken ^c   Califano, Andrea ^a   Iavarone, Antonio ^a   Lasorella, Anna ^a  

^a NewYork Presbyterian Hospital   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

CELLCYCLE; DEVBIO; STEMCELL

Indexed keywords

DLL3 PROTEIN; HUWE1 PROTEIN; MYC PROTEIN; NOTCH RECEPTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EPIGENETICS; GENE INACTIVATION; GLIOMA; HEMIZYGOSITY; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEWBORN; NEWBORN DEATH; NONHUMAN; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; UBIQUITINATION;

ANIMALS; BRAIN; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEUROGENESIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; STEM CELLS; UBIQUITIN-PROTEIN LIGASES;

EID: 68349116164     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2009.07.009     Document Type: Article

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