-
1
-
-
34247259568
-
Drug-induced liver injury
-
G.Abboud, N.Kaplowitz Drug-induced liver injury. Drug Saf. 2007;30:277–294.
-
(2007)
Drug Saf
, vol.30
, pp. 277-294
-
-
Abboud, G.1
Kaplowitz, N.2
-
3
-
-
33947204690
-
Mitochondrial abnormalities–a link to idiosyncratic drug hepatotoxicity?
-
U.A.Boelsterli, P.L.Lim. Mitochondrial abnormalities–a link to idiosyncratic drug hepatotoxicity? Toxicol Appl Pharmacol. 2007;220:92–107.
-
(2007)
Toxicol Appl Pharmacol
, vol.220
, pp. 92-107
-
-
Boelsterli, U.A.1
Lim, P.L.2
-
4
-
-
84890094952
-
Models of hepatotoxicity and the underlying cellular, biochemical and immunological mechanism(s): a critical discussion
-
D.K.Ingawale, S.K.Mandlik, S.R.Naik. Models of hepatotoxicity and the underlying cellular, biochemical and immunological mechanism(s):a critical discussion. Environ Toxicol Pharmacol. 2014;37:118–133.• A review which focuses and discusses on probable underlying cellular, molecular, immunological, and biochemical mechanisms of hepatotoxicity in vivo animal models and in vitro methods.
-
(2014)
Environ Toxicol Pharmacol
, vol.37
, pp. 118-133
-
-
Ingawale, D.K.1
Mandlik, S.K.2
Naik, S.R.3
-
5
-
-
0037126649
-
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
-
G.Ostapowicz, R.J.Fontana, F.V.Schiødt, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med. 2002;137:947–954.
-
(2002)
Ann Intern Med
, vol.137
, pp. 947-954
-
-
Ostapowicz, G.1
Fontana, R.J.2
Schiødt, F.V.3
-
6
-
-
85089885150
-
Drug induced liver injury: review with a focus on genetic factors, tissue diagnosis, and treatment options
-
T.Khoury, A.A.Rmeileh, L.Yosha, et al. Drug induced liver injury:review with a focus on genetic factors, tissue diagnosis, and treatment options. J Clin Transl Hepatol. 2015;3:99–108.
-
(2015)
J Clin Transl Hepatol
, vol.3
, pp. 99-108
-
-
Khoury, T.1
Rmeileh, A.A.2
Yosha, L.3
-
7
-
-
84884954702
-
Drug-induced acute liver failure
-
viii
-
W.M.Lee. Drug-induced acute liver failure. Clin Liver Dis. 2013;17:575–586, viii.
-
(2013)
Clin Liver Dis
, vol.17
, pp. 575-586
-
-
Lee, W.M.1
-
8
-
-
79956321804
-
Drug safety sciences and the bottleneck in drug development
-
P.B.Watkins. Drug safety sciences and the bottleneck in drug development. Clin Pharmacol Ther. 2011;89:788–790.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 788-790
-
-
Watkins, P.B.1
-
10
-
-
84919465499
-
Cell death and cell death responses in liver disease: mechanisms and clinical relevance
-
T.Luedde, N.Kaplowitz, R.F.Schwabe. Cell death and cell death responses in liver disease:mechanisms and clinical relevance. Gastroenterology. 2014;147:765–783; e764.
-
(2014)
Gastroenterology
, vol.147
-
-
Luedde, T.1
Kaplowitz, N.2
Schwabe, R.F.3
-
11
-
-
84903787701
-
Mechanisms of drug-induced liver injury
-
C.Stephens, R.J.Andrade, M.I.Lucena. Mechanisms of drug-induced liver injury. Curr Opin Allergy Clin Immunol. 2014;14:286–292.• A review which summarizes the current understanding of the molecular mechanism behind idiosyncratic DILI.
-
(2014)
Curr Opin Allergy Clin Immunol
, vol.14
, pp. 286-292
-
-
Stephens, C.1
Andrade, R.J.2
Lucena, M.I.3
-
12
-
-
58149347349
-
Drug-induced liver injury network (DILIN) prospective study: rationale, design and conduct
-
R.J.Fontana, P.B.Watkins, H.L.Bonkovsky, et al. Drug-induced liver injury network (DILIN) prospective study:rationale, design and conduct. Drug Saf. 2009;32:55–68.
-
(2009)
Drug Saf
, vol.32
, pp. 55-68
-
-
Fontana, R.J.1
Watkins, P.B.2
Bonkovsky, H.L.3
-
13
-
-
65449146368
-
Drug-induced liver injury in Japan: an analysis of 1676 cases between 1997 and 2006
-
H.Takikawa, Y.Murata, N.Horiike, et al. Drug-induced liver injury in Japan:an analysis of 1676 cases between 1997 and 2006. Hepatol Res. 2009;39:427–431.
-
(2009)
Hepatol Res
, vol.39
, pp. 427-431
-
-
Takikawa, H.1
Murata, Y.2
Horiike, N.3
-
14
-
-
33745174840
-
EUDRAGENE: European collaboration to establish a case-control DNA collection for studying the genetic basis of adverse drug reactions
-
M.Molokhia, P.McKeigue. EUDRAGENE:European collaboration to establish a case-control DNA collection for studying the genetic basis of adverse drug reactions. Pharmacogenomics. 2006;7:633–638.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 633-638
-
-
Molokhia, M.1
McKeigue, P.2
-
15
-
-
18744376412
-
Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period
-
R.J.Andrade, M.I.Lucena, M.C.Fernández, et al. Drug-induced liver injury:an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology. 2005;129:512–521.
-
(2005)
Gastroenterology
, vol.129
, pp. 512-521
-
-
Andrade, R.J.1
Lucena, M.I.2
Fernández, M.C.3
-
18
-
-
84860255967
-
The importance of vancomycin in drug rash with eosinophilia and systemic symptoms (DRESS) syndrome
-
K.G.Blumenthal, S.U.Patil, A.A.Long. The importance of vancomycin in drug rash with eosinophilia and systemic symptoms (DRESS) syndrome. Allergy Asthma Proc. 2012;33:165–171.
-
(2012)
Allergy Asthma Proc
, vol.33
, pp. 165-171
-
-
Blumenthal, K.G.1
Patil, S.U.2
Long, A.A.3
-
19
-
-
53549124403
-
Hepatotoxicity associated with antiepileptic drugs
-
E.Björnsson. Hepatotoxicity associated with antiepileptic drugs. Acta Neurol Scand. 2008;118:281–290.
-
(2008)
Acta Neurol Scand
, vol.118
, pp. 281-290
-
-
Björnsson, E.1
-
20
-
-
0027293230
-
Acute liver failure: redefining the syndromes
-
J.G.O’Grady, S.W.Schalm, R.Williams. Acute liver failure:redefining the syndromes. Lancet. 1993;342:273–275.
-
(1993)
Lancet
, vol.342
, pp. 273-275
-
-
O’Grady, J.G.1
Schalm, S.W.2
Williams, R.3
-
21
-
-
68349141269
-
Outcome of liver transplantation for drug-induced acute liver failure in the United States: analysis of the united network for organ sharing database
-
A.L.Mindikoglu, L.S.Magder, A.Regev. Outcome of liver transplantation for drug-induced acute liver failure in the United States:analysis of the united network for organ sharing database. Liver Transpl. 2009;15:719–729.
-
(2009)
Liver Transpl
, vol.15
, pp. 719-729
-
-
Mindikoglu, A.L.1
Magder, L.S.2
Regev, A.3
-
22
-
-
0036787433
-
AGA technical review on the evaluation of liver chemistry tests
-
R.M.Green, S.Flamm. AGA technical review on the evaluation of liver chemistry tests. Gastroenterology. 2002;123:1367–1384.
-
(2002)
Gastroenterology
, vol.123
, pp. 1367-1384
-
-
Green, R.M.1
Flamm, S.2
-
23
-
-
60349087845
-
Monitoring for hepatotoxicity: what is the predictive value of liver “function” tests?
-
J.R.Senior. Monitoring for hepatotoxicity:what is the predictive value of liver “function” tests? Clin Pharmacol Ther. 2009;85:331–334.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 331-334
-
-
Senior, J.R.1
-
24
-
-
33645220583
-
Drug-induced liver injury: summary of a single topic clinical research conference
-
P.B.Watkins, L.B.Seeff. Drug-induced liver injury:summary of a single topic clinical research conference. Hepatology. 2006;43:618–631.
-
(2006)
Hepatology
, vol.43
, pp. 618-631
-
-
Watkins, P.B.1
Seeff, L.B.2
-
25
-
-
0025227871
-
Criteria of drug-induced liver disorders. Report of an international consensus meeting
-
C.Bénichou. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol. 1990;11:272–276.
-
(1990)
J Hepatol
, vol.11
, pp. 272-276
-
-
Bénichou, C.1
-
26
-
-
84958521541
-
Liver injury from herbal, dietary, and weight loss supplements: a review
-
E.X.Zheng, V.J.Navarro. Liver injury from herbal, dietary, and weight loss supplements:a review. J Clin Transl Hepatol. 2015;3:93–98.•• A review which highlights the hepatotoxic potential of HDS weight loss products and provides an effort to outline a diagnostic approach for DILI.
-
(2015)
J Clin Transl Hepatol
, vol.3
, pp. 93-98
-
-
Zheng, E.X.1
Navarro, V.J.2
-
27
-
-
84944388631
-
The art and science of diagnosing and managing drug-induced liver injury in 2015 and beyond
-
J.H.Lewis. The art and science of diagnosing and managing drug-induced liver injury in 2015 and beyond. Clin Gastroenterol Hepatol. 2015;13:2173–2189; e2178.• A review which summarize the current guidelines of diagnosing and managing DILI.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
-
-
Lewis, J.H.1
-
28
-
-
84901766171
-
Clinical features, diagnosis, and natural history of drug-induced liver injury
-
P.H.Hayashi, R.J.Fontana. Clinical features, diagnosis, and natural history of drug-induced liver injury. Semin Liver Dis. 2014;34:134–144.
-
(2014)
Semin Liver Dis
, vol.34
, pp. 134-144
-
-
Hayashi, P.H.1
Fontana, R.J.2
-
29
-
-
77950508162
-
Biomarkers for drug-induced liver injury
-
Q.Shi, H.Hong, J.Senior, et al. Biomarkers for drug-induced liver injury. Expert Rev Gastroenterol Hepatol. 2010;4:225–234.•• A review which summarizes the current practice and future perspectives for DILI biomarkers.
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 225-234
-
-
Shi, Q.1
Hong, H.2
Senior, J.3
-
30
-
-
84893663493
-
Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance
-
N.M.Steuerwald, D.M.Foureau, H.J.Norton, et al. Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance. PLoS One. 2013;8:e81974.
-
(2013)
PLoS One
, vol.8
, pp. e81974
-
-
Steuerwald, N.M.1
Foureau, D.M.2
Norton, H.J.3
-
31
-
-
80055038826
-
Circulating microRNAs as potential markers of human drug-induced liver injury
-
P.J.Starkey Lewis, J.Dear, V.Platt, et al. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology. 2011;54:1767–1776.•• A study which provides the evidence for the potential use of miRNAs as biomarkers of human drug-induced liver injury.
-
(2011)
Hepatology
, vol.54
, pp. 1767-1776
-
-
Starkey Lewis, P.J.1
Dear, J.2
Platt, V.3
-
32
-
-
84924626906
-
Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases
-
C.Roderburg, F.Benz, D.Vargas Cardenas, et al. Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases. Liver Int. 2015;35:1172–1184.
-
(2015)
Liver Int
, vol.35
, pp. 1172-1184
-
-
Roderburg, C.1
Benz, F.2
Vargas Cardenas, D.3
-
33
-
-
70349406480
-
Current concepts of mechanisms in drug-induced hepatotoxicity
-
S.Russmann, G.A.Kullak-Ublick, I.Grattagliano. Current concepts of mechanisms in drug-induced hepatotoxicity. Curr Med Chem. 2009;16:3041–3053.
-
(2009)
Curr Med Chem
, vol.16
, pp. 3041-3053
-
-
Russmann, S.1
Kullak-Ublick, G.A.2
Grattagliano, I.3
-
34
-
-
84896450857
-
Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives
-
R.J.Fontana. Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives. Gastroenterology. 2014;146:914–928.
-
(2014)
Gastroenterology
, vol.146
, pp. 914-928
-
-
Fontana, R.J.1
-
35
-
-
84896364866
-
Mechanisms of isoniazid-induced idiosyncratic liver injury: emerging role of mitochondrial stress
-
U.A.Boelsterli, K.K.Lee. Mechanisms of isoniazid-induced idiosyncratic liver injury:emerging role of mitochondrial stress. J Gastroenterol Hepatol. 2014;29:678–687.
-
(2014)
J Gastroenterol Hepatol
, vol.29
, pp. 678-687
-
-
Boelsterli, U.A.1
Lee, K.K.2
-
36
-
-
68149154046
-
Getting harder: cobalt(III)-template synthesis of catenanes and rotaxanes
-
D.A.Leigh, P.J.Lusby, R.T.McBurney, et al. Getting harder:cobalt(III)-template synthesis of catenanes and rotaxanes. J Am Chem Soc. 2009;131:3762–3771.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 3762-3771
-
-
Leigh, D.A.1
Lusby, P.J.2
McBurney, R.T.3
-
37
-
-
84875537173
-
Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry
-
L.Saab, J.Peluso, C.D.Muller, et al. Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry. Cytometry A. 2013;83:403–408.
-
(2013)
Cytometry A
, vol.83
, pp. 403-408
-
-
Saab, L.1
Peluso, J.2
Muller, C.D.3
-
38
-
-
84905375362
-
Mechanistic modeling reveals the critical knowledge gaps in bile acid-mediated DILI
-
J.L.Woodhead, K.Yang, K.L.Brouwer, et al. Mechanistic modeling reveals the critical knowledge gaps in bile acid-mediated DILI. CPT Pharmacometrics Syst Pharmacol. 2014;3:e123.
-
(2014)
CPT Pharmacometrics Syst Pharmacol
, vol.3
, pp. e123
-
-
Woodhead, J.L.1
Yang, K.2
Brouwer, K.L.3
-
39
-
-
84940374086
-
Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors
-
M.A.Welch, K.Kock, T.J.Urban, et al. Toward predicting drug-induced liver injury:parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors. Drug Metab Dispos. 2015;43:725–734.
-
(2015)
Drug Metab Dispos
, vol.43
, pp. 725-734
-
-
Welch, M.A.1
Kock, K.2
Urban, T.J.3
-
40
-
-
77954069495
-
Mechanisms of immune-mediated liver injury
-
D.H.Adams, C.Ju, S.K.Ramaiah, et al. Mechanisms of immune-mediated liver injury. Toxicol Sci. 2010;115:307–321.
-
(2010)
Toxicol Sci
, vol.115
, pp. 307-321
-
-
Adams, D.H.1
Ju, C.2
Ramaiah, S.K.3
-
41
-
-
84880763009
-
Idiosyncratic adverse drug reactions: current concepts
-
J.Uetrecht, D.J.Naisbitt. Idiosyncratic adverse drug reactions:current concepts. Pharmacol Rev. 2013;65:779–808.
-
(2013)
Pharmacol Rev
, vol.65
, pp. 779-808
-
-
Uetrecht, J.1
Naisbitt, D.J.2
-
42
-
-
79958175637
-
Review article: drug-induced liver injury–its pathophysiology and evolving diagnostic tools
-
J.S.Au, V.J.Navarro, S.Rossi. Review article:drug-induced liver injury–its pathophysiology and evolving diagnostic tools. Aliment Pharmacol Ther. 2011;34:11–20.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 11-20
-
-
Au, J.S.1
Navarro, V.J.2
Rossi, S.3
-
43
-
-
84919839425
-
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model
-
J.W.Eun, H.J.Bae, Q.Shen, et al. Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. J Appl Toxicol. 2015;35:152–164.
-
(2015)
J Appl Toxicol
, vol.35
, pp. 152-164
-
-
Eun, J.W.1
Bae, H.J.2
Shen, Q.3
-
44
-
-
84924732907
-
FutureTox II: in vitro data and in silico models for predictive toxicology
-
T.B.Knudsen, D.A.Keller, M.Sander, et al. FutureTox II:in vitro data and in silico models for predictive toxicology. Toxicol Sci. 2015;143:256–267.
-
(2015)
Toxicol Sci
, vol.143
, pp. 256-267
-
-
Knudsen, T.B.1
Keller, D.A.2
Sander, M.3
-
45
-
-
33344462585
-
Minimising the potential for metabolic activation in drug discovery
-
A.S.Kalgutkar, J.R.Soglia. Minimising the potential for metabolic activation in drug discovery. Expert Opin Drug Metab Toxicol. 2005;1:91–142.
-
(2005)
Expert Opin Drug Metab Toxicol
, vol.1
, pp. 91-142
-
-
Kalgutkar, A.S.1
Soglia, J.R.2
-
46
-
-
77249143567
-
Intrinsic versus idiosyncratic drug-induced hepatotoxicity–two villains or one?
-
R.A.Roth, P.E.Ganey. Intrinsic versus idiosyncratic drug-induced hepatotoxicity–two villains or one? J Pharmacol Exp Ther. 2010;332:692–697.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 692-697
-
-
Roth, R.A.1
Ganey, P.E.2
-
48
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
-
J.R.Mitchell, D.J.Jollow, W.Z.Potter, et al. Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther. 1973;187:185–194.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
-
49
-
-
77749262361
-
Mechanisms of acetaminophen-induced liver necrosis
-
J.A.Hinson, D.W.Roberts, L.P.James. Mechanisms of acetaminophen-induced liver necrosis. Handb Exp Pharmacol. 2010;(196):369–405. doi:10.1007/978-3-642-00663-0_12.
-
(2010)
Handb Exp Pharmacol
, vol.196
, pp. 369-405
-
-
Hinson, J.A.1
Roberts, D.W.2
James, L.P.3
-
50
-
-
84893699696
-
Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations
-
D.E.Kleiner, N.P.Chalasani, W.M.Lee, et al. Hepatic histological findings in suspected drug-induced liver injury:systematic evaluation and clinical associations. Hepatology. 2014;59:661–670.• A review to provide an overview of the prevalence, classification, and diagnosis of DILI with emphasis on the histologic pattern of injury observed.
-
(2014)
Hepatology
, vol.59
, pp. 661-670
-
-
Kleiner, D.E.1
Chalasani, N.P.2
Lee, W.M.3
-
51
-
-
0029978235
-
Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts
-
W.Lewis, E.S.Levine, B.Griniuviene, et al. Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts. Proc Natl Acad Sci U S A. 1996;93:3592–3597.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3592-3597
-
-
Lewis, W.1
Levine, E.S.2
Griniuviene, B.3
-
52
-
-
34249803204
-
The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury
-
E.Björnsson, E.Kalaitzakis, R.Olsson. The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury. Aliment Pharmacol Ther. 2007;25:1411–1421.
-
(2007)
Aliment Pharmacol Ther
, vol.25
, pp. 1411-1421
-
-
Björnsson, E.1
Kalaitzakis, E.2
Olsson, R.3
-
53
-
-
38949104743
-
Idiosyncratic drug reactions: past, present, and future
-
J.Uetrecht. Idiosyncratic drug reactions:past, present, and future. Chem Res Toxicol. 2008;21:84–92.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 84-92
-
-
Uetrecht, J.1
-
54
-
-
0031719374
-
Role of drug disposition in drug hypersensitivity: a chemical, molecular, and clinical perspective
-
B.K.Park, M.Pirmohamed, N.R.Kitteringham. Role of drug disposition in drug hypersensitivity:a chemical, molecular, and clinical perspective. Chem Res Toxicol. 1998;11:969–988.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 969-988
-
-
Park, B.K.1
Pirmohamed, M.2
Kitteringham, N.R.3
-
55
-
-
17644393164
-
Tolerogenic role of Kupffer cells in immune-mediated adverse drug reactions
-
C.Ju, L.R.Pohl. Tolerogenic role of Kupffer cells in immune-mediated adverse drug reactions. Toxicology. 2005;209:109–112.
-
(2005)
Toxicology
, vol.209
, pp. 109-112
-
-
Ju, C.1
Pohl, L.R.2
-
56
-
-
0036676978
-
Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept
-
W.J.Pichler. Pharmacological interaction of drugs with antigen-specific immune receptors:the p-i concept. Curr Opin Allergy Clin Immunol. 2002;2:301–305.
-
(2002)
Curr Opin Allergy Clin Immunol
, vol.2
, pp. 301-305
-
-
Pichler, W.J.1
-
57
-
-
77952836903
-
Isoniazid-induced apoptosis in HepG2 cells: generation of oxidative stress and Bcl-2 down-regulation
-
S.Bhadauria, R.Mishra, R.Kanchan, et al. Isoniazid-induced apoptosis in HepG2 cells:generation of oxidative stress and Bcl-2 down-regulation. Toxicol Mech Methods. 2010;20:242–251.
-
(2010)
Toxicol Mech Methods
, vol.20
, pp. 242-251
-
-
Bhadauria, S.1
Mishra, R.2
Kanchan, R.3
-
58
-
-
79952007967
-
The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity
-
A.Ramachandran, M.Lebofsky, S.A.Weinman, et al. The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity. Toxicol Appl Pharmacol. 2011;251:226–233.
-
(2011)
Toxicol Appl Pharmacol
, vol.251
, pp. 226-233
-
-
Ramachandran, A.1
Lebofsky, M.2
Weinman, S.A.3
-
59
-
-
56349103630
-
Role of cytochrome P450 in drug interactions
-
Z.Bibi. Role of cytochrome P450 in drug interactions. Nutr Metab (Lond). 2008;5:27.
-
(2008)
Nutr Metab (Lond)
, vol.5
, pp. 27
-
-
Bibi, Z.1
-
60
-
-
84873854068
-
Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies
-
U.A.Boelsterli, M.R.Redinbo, K.S.Saitta. Multiple NSAID-induced hits injure the small intestine:underlying mechanisms and novel strategies. Toxicol Sci. 2013;131:654–667.
-
(2013)
Toxicol Sci
, vol.131
, pp. 654-667
-
-
Boelsterli, U.A.1
Redinbo, M.R.2
Saitta, K.S.3
-
61
-
-
84901768135
-
Genetic basis of drug-induced liver injury: present and future
-
T.J.Urban, A.K.Daly, G.P.Aithal. Genetic basis of drug-induced liver injury:present and future. Semin Liver Dis. 2014;34:123–133.
-
(2014)
Semin Liver Dis
, vol.34
, pp. 123-133
-
-
Urban, T.J.1
Daly, A.K.2
Aithal, G.P.3
-
62
-
-
84899808918
-
Future of pharmacogenetics-based therapy for tuberculosis
-
T.Matsumoto, M.Ohno, J.Azuma. Future of pharmacogenetics-based therapy for tuberculosis. Pharmacogenomics. 2014;15:601–607.
-
(2014)
Pharmacogenomics
, vol.15
, pp. 601-607
-
-
Matsumoto, T.1
Ohno, M.2
Azuma, J.3
-
63
-
-
84942821013
-
Drug-induced liver injury: interactions between drug properties and host factors
-
M.Chen, A.Suzuki, J.Borlak, et al. Drug-induced liver injury:interactions between drug properties and host factors. J Hepatol. 2015;63:503–514.
-
(2015)
J Hepatol
, vol.63
, pp. 503-514
-
-
Chen, M.1
Suzuki, A.2
Borlak, J.3
-
64
-
-
84931560498
-
Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice
-
G.P.Aithal. Pharmacogenetic testing in idiosyncratic drug-induced liver injury:current role in clinical practice. Liver Int. 2015;35:1801–1808.
-
(2015)
Liver Int
, vol.35
, pp. 1801-1808
-
-
Aithal, G.P.1
-
65
-
-
84903897064
-
ACG clinical guideline: the diagnosis and management of idiosyncratic drug-induced liver injury
-
N.P.Chalasani, P.H.Hayashi, H.L.Bonkovsky, et al. ACG clinical guideline:the diagnosis and management of idiosyncratic drug-induced liver injury. Am J Gastroenterol. 2014;109:950–966; quiz 967.
-
(2014)
Am J Gastroenterol
, vol.109
-
-
Chalasani, N.P.1
Hayashi, P.H.2
Bonkovsky, H.L.3
-
66
-
-
77952718055
-
Risk factors for idiosyncratic drug-induced liver injury
-
N.Chalasani, E.Björnsson. Risk factors for idiosyncratic drug-induced liver injury. Gastroenterology. 2010;138:2246–2259.
-
(2010)
Gastroenterology
, vol.138
, pp. 2246-2259
-
-
Chalasani, N.1
Björnsson, E.2
-
67
-
-
84944373283
-
Public health service study of Reye’s syndrome and medications. Report of the main study
-
E.S.Hurwitz, M.J.Barrett, D.Bregman, et al. Public health service study of Reye’s syndrome and medications. Report of the main study. JAMA. 1987;257:1905–1911.
-
(1987)
JAMA
, vol.257
, pp. 1905-1911
-
-
Hurwitz, E.S.1
Barrett, M.J.2
Bregman, D.3
-
68
-
-
0023789945
-
Fatal liver failure in 16 children with valproate therapy
-
D.Scheffner, S.König, I.Rauterberg-Ruland, et al. Fatal liver failure in 16 children with valproate therapy. Epilepsia. 1988;29:530–542.
-
(1988)
Epilepsia
, vol.29
, pp. 530-542
-
-
Scheffner, D.1
König, S.2
Rauterberg-Ruland, I.3
-
69
-
-
22244492630
-
Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: a 7-year evaluation from a public health tuberculosis clinic
-
F.F.Fountain, E.Tolley, C.R.Chrisman, et al. Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection:a 7-year evaluation from a public health tuberculosis clinic. Chest. 2005;128:116–123.
-
(2005)
Chest
, vol.128
, pp. 116-123
-
-
Fountain, F.F.1
Tolley, E.2
Chrisman, C.R.3
-
70
-
-
33750632721
-
Determinants of the clinical expression of amoxicillin-clavulanate hepatotoxicity: a prospective series from Spain
-
M.I.Lucena, R.J.Andrade, M.C.Fernández, et al. Determinants of the clinical expression of amoxicillin-clavulanate hepatotoxicity:a prospective series from Spain. Hepatology. 2006;44:850–856.
-
(2006)
Hepatology
, vol.44
, pp. 850-856
-
-
Lucena, M.I.1
Andrade, R.J.2
Fernández, M.C.3
-
71
-
-
75449112589
-
Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events
-
C.Lammert, E.Bjornsson, A.Niklasson, et al. Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events. Hepatology. 2010;51:615–620.
-
(2010)
Hepatology
, vol.51
, pp. 615-620
-
-
Lammert, C.1
Bjornsson, E.2
Niklasson, A.3
-
72
-
-
84879605416
-
High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury
-
M.Chen, J.Borlak, W.Tong. High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury. Hepatology. 2013;58:388–396.
-
(2013)
Hepatology
, vol.58
, pp. 388-396
-
-
Chen, M.1
Borlak, J.2
Tong, W.3
-
73
-
-
84879602720
-
Avoiding idiosyncratic DILI: two is better than one
-
N.Kaplowitz. Avoiding idiosyncratic DILI:two is better than one. Hepatology. 2013;58:15–17.
-
(2013)
Hepatology
, vol.58
, pp. 15-17
-
-
Kaplowitz, N.1
-
74
-
-
68149166599
-
Altered functions and expressions of drug transporters in liver, kidney and intestine in disorders of local and remote organs: possible role of oxidative stress in the pathogenesis
-
K.Ikemura, T.Iwamoto, M.Okuda. Altered functions and expressions of drug transporters in liver, kidney and intestine in disorders of local and remote organs:possible role of oxidative stress in the pathogenesis. Expert Opin Drug Metab Toxicol. 2009;5:907–920.
-
(2009)
Expert Opin Drug Metab Toxicol
, vol.5
, pp. 907-920
-
-
Ikemura, K.1
Iwamoto, T.2
Okuda, M.3
-
75
-
-
57049161412
-
Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction
-
R.K.Verbeeck. Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction. Eur J Clin Pharmacol. 2008;64:1147–1161.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 1147-1161
-
-
Verbeeck, R.K.1
-
76
-
-
84855908033
-
Genetic association studies in drug-induced liver injury
-
A.K.Daly, C.P.Day. Genetic association studies in drug-induced liver injury. Drug Metab Rev. 2012;44:116–126.
-
(2012)
Drug Metab Rev
, vol.44
, pp. 116-126
-
-
Daly, A.K.1
Day, C.P.2
-
77
-
-
78049516212
-
Polymerase gamma gene POLG determines the risk of sodium valproate-induced liver toxicity
-
J.D.Stewart, R.Horvath, E.Baruffini, et al. Polymerase gamma gene POLG determines the risk of sodium valproate-induced liver toxicity. Hepatology. 2010;52:1791–1796.
-
(2010)
Hepatology
, vol.52
, pp. 1791-1796
-
-
Stewart, J.D.1
Horvath, R.2
Baruffini, E.3
-
78
-
-
79957523368
-
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles
-
M.I.Lucena, M.Molokhia, Y.Shen, et al. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology. 2011;141:338–347.
-
(2011)
Gastroenterology
, vol.141
, pp. 338-347
-
-
Lucena, M.I.1
Molokhia, M.2
Shen, Y.3
-
79
-
-
84879990042
-
HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity
-
C.Stephens, M.A.Lopez-Nevot, F.Ruiz-Cabello, et al. HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity. PLoS One. 2013;8:e68111.
-
(2013)
PLoS One
, vol.8
, pp. e68111
-
-
Stephens, C.1
Lopez-Nevot, M.A.2
Ruiz-Cabello, F.3
-
80
-
-
84932108291
-
Pharmacogenetics of isoniazid-induced hepatotoxicity
-
D.A.Perwitasari, J.Atthobari, B.Wilffert. Pharmacogenetics of isoniazid-induced hepatotoxicity. Drug Metab Rev. 2015;47:222–228.•• A review to clarify the role and the pharmacological mechanism of the genes involved in the isoniazid-induced hepatotoxicity, especially the pharmacological mechanism of some genes involved in the expression of reactive oxygen species (ROS).
-
(2015)
Drug Metab Rev
, vol.47
, pp. 222-228
-
-
Perwitasari, D.A.1
Atthobari, J.2
Wilffert, B.3
-
81
-
-
0036796798
-
Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment
-
S.K.Sharma, A.Balamurugan, P.K.Saha, et al. Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment. Am J Respir Crit Care Med. 2002;166:916–919.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 916-919
-
-
Sharma, S.K.1
Balamurugan, A.2
Saha, P.K.3
-
82
-
-
84879505702
-
Presentation and outcomes with clinically apparent interferon beta hepatotoxicity
-
R.J.Fontana, P.Hayashi, H.L.Bonkovsky, et al. Presentation and outcomes with clinically apparent interferon beta hepatotoxicity. Dig Dis Sci. 2013;58:1766–1775.
-
(2013)
Dig Dis Sci
, vol.58
, pp. 1766-1775
-
-
Fontana, R.J.1
Hayashi, P.2
Bonkovsky, H.L.3
-
83
-
-
70449109529
-
Biomarkers for the diagnosis and management of drug-induced liver injury
-
P.B.Watkins. Biomarkers for the diagnosis and management of drug-induced liver injury. Semin Liver Dis. 2009;29:393–399.
-
(2009)
Semin Liver Dis
, vol.29
, pp. 393-399
-
-
Watkins, P.B.1
-
84
-
-
84878075137
-
Herbal hepatotoxicity: challenges and pitfalls of causality assessment methods
-
R.Teschke, C.Frenzel, J.Schulze, et al. Herbal hepatotoxicity:challenges and pitfalls of causality assessment methods. World J Gastroenterol. 2013;19:2864–2882.
-
(2013)
World J Gastroenterol
, vol.19
, pp. 2864-2882
-
-
Teschke, R.1
Frenzel, C.2
Schulze, J.3
-
85
-
-
80054848088
-
Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury
-
T.J.Davern, N.Chalasani, R.J.Fontana, et al. Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. Gastroenterology. 2011;141:1665–1672; e1661–e1669.
-
(2011)
Gastroenterology
, vol.141
-
-
Davern, T.J.1
Chalasani, N.2
Fontana, R.J.3
-
86
-
-
40849149611
-
Evaluation of naranjo adverse drug reactions probability scale in causality assessment of drug-induced liver injury
-
M.García-Cortés, M.I.Lucena, K.Pachkoria, et al. Evaluation of naranjo adverse drug reactions probability scale in causality assessment of drug-induced liver injury. Aliment Pharmacol Ther. 2008;27:780–789.
-
(2008)
Aliment Pharmacol Ther
, vol.27
, pp. 780-789
-
-
García-Cortés, M.1
Lucena, M.I.2
Pachkoria, K.3
-
87
-
-
0035200244
-
Comparison of two clinical scales for causality assessment in hepatotoxicity
-
M.I.Lucena, R.Camargo, R.J.Andrade, et al. Comparison of two clinical scales for causality assessment in hepatotoxicity. Hepatology. 2001;33:123–130.
-
(2001)
Hepatology
, vol.33
, pp. 123-130
-
-
Lucena, M.I.1
Camargo, R.2
Andrade, R.J.3
-
88
-
-
84893656508
-
Drug induced liver injury: accuracy of diagnosis in published reports
-
R.Teschke, C.Frenzel, A.Wolff, et al. Drug induced liver injury:accuracy of diagnosis in published reports. Ann Hepatol. 2014;13:248–255.
-
(2014)
Ann Hepatol
, vol.13
, pp. 248-255
-
-
Teschke, R.1
Frenzel, C.2
Wolff, A.3
-
89
-
-
0033547542
-
Accuracy of hepatic adverse drug reaction reporting in one English health region
-
G.P.Aithal, M.D.Rawlins, C.P.Day. Accuracy of hepatic adverse drug reaction reporting in one English health region. BMJ. 1999;319:1541.
-
(1999)
BMJ
, vol.319
, pp. 1541
-
-
Aithal, G.P.1
Rawlins, M.D.2
Day, C.P.3
-
90
-
-
0029552748
-
Morphologic spectrum of drug-induced hepatic disease
-
K.G.Ishak, H.J.Zimmerman. Morphologic spectrum of drug-induced hepatic disease. Gastroenterol Clin North Am. 1995;24:759–786.
-
(1995)
Gastroenterol Clin North Am
, vol.24
, pp. 759-786
-
-
Ishak, K.G.1
Zimmerman, H.J.2
-
91
-
-
57249086242
-
Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States
-
1934; e1921–e1924
-
N.Chalasani, R.J.Fontana, H.L.Bonkovsky, et al. Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology. 2008;135:1924–1934, 1934; e1921–e1924.
-
(2008)
Gastroenterology
, vol.135
, pp. 1924-1934
-
-
Chalasani, N.1
Fontana, R.J.2
Bonkovsky, H.L.3
-
92
-
-
80052023773
-
The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury
-
A.Suzuki, E.M.Brunt, D.E.Kleiner, et al. The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury. Hepatology. 2011;54:931–939.
-
(2011)
Hepatology
, vol.54
, pp. 931-939
-
-
Suzuki, A.1
Brunt, E.M.2
Kleiner, D.E.3
-
93
-
-
70449124654
-
The pathology of drug-induced liver injury
-
D.E.Kleiner. The pathology of drug-induced liver injury. Semin Liver Dis. 2009;29:364–372.
-
(2009)
Semin Liver Dis
, vol.29
, pp. 364-372
-
-
Kleiner, D.E.1
-
94
-
-
47149112922
-
Simplified criteria for the diagnosis of autoimmune hepatitis
-
E.M.Hennes, M.Zeniya, A.J.Czaja, et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology. 2008;48:169–176.
-
(2008)
Hepatology
, vol.48
, pp. 169-176
-
-
Hennes, E.M.1
Zeniya, M.2
Czaja, A.J.3
-
95
-
-
70449103048
-
Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use
-
K.Raja, S.N.Thung, M.I.Fiel, et al. Drug-induced steatohepatitis leading to cirrhosis:long-term toxicity of amiodarone use. Semin Liver Dis. 2009;29:423–428.
-
(2009)
Semin Liver Dis
, vol.29
, pp. 423-428
-
-
Raja, K.1
Thung, S.N.2
Fiel, M.I.3
-
96
-
-
67649221506
-
Histological patterns in drug-induced liver disease
-
R.Ramachandran, S.Kakar. Histological patterns in drug-induced liver disease. J Clin Pathol. 2009;62:481–492.
-
(2009)
J Clin Pathol
, vol.62
, pp. 481-492
-
-
Ramachandran, R.1
Kakar, S.2
-
97
-
-
0014854624
-
Tetracycline-associated fatty liver in the male. Report of an autopsied case
-
M.J.Robinson, A.M.Rywlin. Tetracycline-associated fatty liver in the male. Report of an autopsied case. Am J Dig Dis. 1970;15:857–862.
-
(1970)
Am J Dig Dis
, vol.15
, pp. 857-862
-
-
Robinson, M.J.1
Rywlin, A.M.2
-
98
-
-
34247203727
-
Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver
-
I.Larosche, P.Lettéron, B.Fromenty, et al. Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver. J Pharmacol Exp Ther. 2007;321:526–535.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 526-535
-
-
Larosche, I.1
Lettéron, P.2
Fromenty, B.3
-
99
-
-
0033792939
-
Hepatic steatosis and lactic acidosis caused by stavudine in an HIV-infected patient
-
C.P.Bleeker-Rovers, S.W.Kadir, R.Van Leusen, et al. Hepatic steatosis and lactic acidosis caused by stavudine in an HIV-infected patient. Neth J Med. 2000;57:190–193.
-
(2000)
Neth J Med
, vol.57
, pp. 190-193
-
-
Bleeker-Rovers, C.P.1
Kadir, S.W.2
Van Leusen, R.3
-
100
-
-
1542327565
-
Drug-induced liver injury
-
N.Kaplowitz. Drug-induced liver injury. Clin Infect Dis. 2004;38(Suppl 2):S44–S48.
-
(2004)
Clin Infect Dis
, vol.38
, pp. S44-S48
-
-
Kaplowitz, N.1
-
101
-
-
57149108312
-
Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury
-
M.P.Holt, L.Cheng, C.Ju. Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury. J Leukoc Biol. 2008;84:1410–1421.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1410-1421
-
-
Holt, M.P.1
Cheng, L.2
Ju, C.3
-
102
-
-
68949100230
-
Prolonged intrahepatic cholestasis and renal failure secondary to anabolic androgenic steroid-enriched dietary supplements
-
P.V.Krishnan, -Z.-Z.Feng, S.C.Gordon. Prolonged intrahepatic cholestasis and renal failure secondary to anabolic androgenic steroid-enriched dietary supplements. J Clin Gastroenterol. 2009;43:672–675.
-
(2009)
J Clin Gastroenterol
, vol.43
, pp. 672-675
-
-
Krishnan, P.V.1
Feng, Z.Z.2
Gordon, S.C.3
-
103
-
-
84865130101
-
Liver injury due to chemotherapy-induced sinusoidal obstruction syndrome is associated with sinusoidal capillarization
-
M.Narita, E.Oussoultzoglou, M.-P.Chenard, et al. Liver injury due to chemotherapy-induced sinusoidal obstruction syndrome is associated with sinusoidal capillarization. Ann Surg Oncol. 2012;19:2230–2237.
-
(2012)
Ann Surg Oncol
, vol.19
, pp. 2230-2237
-
-
Narita, M.1
Oussoultzoglou, E.2
Chenard, M.-P.3
-
104
-
-
84865637635
-
Oxaliplatin-induced hepatocellular injury and ototoxicity: a review of the literature and report of unusual side effects of a commonly used chemotherapeutic agent
-
N.O.Vietor, B.J.George. Oxaliplatin-induced hepatocellular injury and ototoxicity:a review of the literature and report of unusual side effects of a commonly used chemotherapeutic agent. J Oncol Pharm Pract. 2012;18:355–359.
-
(2012)
J Oncol Pharm Pract
, vol.18
, pp. 355-359
-
-
Vietor, N.O.1
George, B.J.2
-
106
-
-
0033045249
-
The natural history of histologically proved drug induced liver disease
-
P.G.Aithal, C.P.Day The natural history of histologically proved drug induced liver disease. Gut. 1999;44:731–735.
-
(1999)
Gut
, vol.44
, pp. 731-735
-
-
Aithal, P.G.1
Day, C.P.2
-
107
-
-
1642272235
-
Drug- and chemical-induced cholestasis
-
R.Mohi-ud-din, J.H.Lewis. Drug- and chemical-induced cholestasis. Clin Liver Dis. 2004;8:95–132, vii.
-
(2004)
Clin Liver Dis
, vol.8
, pp. 95-132, vii
-
-
Mohi-ud-din, R.1
Lewis, J.H.2
-
108
-
-
33845666885
-
Outcome of acute idiosyncratic drug-induced liver injury: long-term follow-up in a hepatotoxicity registry
-
R.J.Andrade, M.I.Lucena, N.Kaplowitz, et al. Outcome of acute idiosyncratic drug-induced liver injury:long-term follow-up in a hepatotoxicity registry. Hepatology. 2006;44:1581–1588.
-
(2006)
Hepatology
, vol.44
, pp. 1581-1588
-
-
Andrade, R.J.1
Lucena, M.I.2
Kaplowitz, N.3
-
109
-
-
84880595486
-
Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics
-
N.T.Ventham, N.A.Kennedy, E.R.Nimmo, et al. Beyond gene discovery in inflammatory bowel disease:the emerging role of epigenetics. Gastroenterology. 2013;145:293–308.
-
(2013)
Gastroenterology
, vol.145
, pp. 293-308
-
-
Ventham, N.T.1
Kennedy, N.A.2
Nimmo, E.R.3
|