메뉴 건너뛰기




Volumn 58, Issue 1, 2013, Pages 15-17

Avoiding idiosyncratic DILI: Two is better than one

Author keywords

[No Author keywords available]

Indexed keywords

BILE SALT; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUMIRACOXIB; OCTANOL; TUMOR NECROSIS FACTOR;

EID: 84879602720     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26295     Document Type: Article
Times cited : (46)

References (18)
  • 1
    • 84882668867 scopus 로고    scopus 로고
    • Drug-Induced Liver Injury: Introduction and Overview in Drug-Induced Liver Disease. Kaplowitz N, DeLeve L, eds. New York: Elsevier; 2013, Chapter 1
    • Kaplowitz N. Drug-Induced Liver Injury: Introduction and Overview in Drug-Induced Liver Disease. Kaplowitz N, DeLeve L, eds. New York: Elsevier; 2013, Chapter 1, p 3-14.
    • Kaplowitz, N.1
  • 2
    • 84879605416 scopus 로고    scopus 로고
    • High lipophilicity and high daily dose of oral medication are associated with signicant risk for drug-induced liver injury
    • Chen M, Borlak J, Tong W. High lipophilicity and high daily dose of oral medication are associated with signicant risk for drug-induced liver injury. HEPATOLOGY 2013; 58: 388-396.
    • (2013) HEPATOLOGY , vol.58 , pp. 388-396
    • Chen, M.1    Borlak, J.2    Tong, W.3
  • 4
    • 46249118651 scopus 로고    scopus 로고
    • Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals
    • Lammert C, Einarsson S, Saha C, Niklasson A, Bjornsson E, Chalasani N. Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals. HEPATOLOGY 2008; 47: 2003-2009.
    • (2008) HEPATOLOGY , vol.47 , pp. 2003-2009
    • Lammert, C.1    Einarsson, S.2    Saha, C.3    Niklasson, A.4    Bjornsson, E.5    Chalasani, N.6
  • 6
    • 65549132575 scopus 로고    scopus 로고
    • Pharmacological promiscuity: dependence on compound properties and target specificity in a set of recent Roche compounds
    • Peters JU, Schnider P, Mattei P, Kansy M. Pharmacological promiscuity: dependence on compound properties and target specificity in a set of recent Roche compounds. Chem Med Chem 2009; 4: 680-686.
    • (2009) Chem Med Chem , vol.4 , pp. 680-686
    • Peters, J.U.1    Schnider, P.2    Mattei, P.3    Kansy, M.4
  • 7
    • 65449179589 scopus 로고    scopus 로고
    • Defining optimum lipophilicity and molecular weight ranges for drug candidates. Molecular weight dependent lower logD limits based on permeability
    • Waring MJ. Defining optimum lipophilicity and molecular weight ranges for drug candidates. Molecular weight dependent lower logD limits based on permeability. Bioorg Med Chem Lett 2009; 19: 2844-2851.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 2844-2851
    • Waring, M.J.1
  • 8
    • 75449112589 scopus 로고    scopus 로고
    • Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events
    • Lammert C, Bjornsson E, Niklasson A, Chalasani N. Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events. HEPATOLOGY 2010; 51: 615-20.
    • (2010) HEPATOLOGY , vol.51 , pp. 615-620
    • Lammert, C.1    Bjornsson, E.2    Niklasson, A.3    Chalasani, N.4
  • 9
    • 84879602665 scopus 로고    scopus 로고
    • Micropatterned co-cultures increase the ability to detect compounds that cause drug induced liver injury in humans over sandwich cultures
    • Khetani S, Kanchagar C, Krzyzewski C, Krzyzewski S, Moore A, Shi J, et al. Micropatterned co-cultures increase the ability to detect compounds that cause drug induced liver injury in humans over sandwich cultures. Toxicol Sci [published online] 2012.
    • (2012) Toxicol Sci [published online]
    • Khetani, S.1    Kanchagar, C.2    Krzyzewski, C.3    Krzyzewski, S.4    Moore, A.5    Shi, J.6
  • 10
    • 84866596506 scopus 로고    scopus 로고
    • Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria
    • Porceddu M, Buron N, Roussel C, Labbe G, Fromenty B, Borgne_Sanchez A. Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Toxicol Sci 2012; 129: 332-345.
    • (2012) Toxicol Sci , vol.129 , pp. 332-345
    • Porceddu, M.1    Buron, N.2    Roussel, C.3    Labbe, G.4    Fromenty, B.5    Borgne-Sanchez, A.6
  • 11
    • 78549248177 scopus 로고    scopus 로고
    • Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development
    • Morgan RE, Trauner M, van Staden CJ, Lee PH, Ramachandran B, Eschenberg M, et al. Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicol Sci 2010; 118: 485-500.
    • (2010) Toxicol Sci , vol.118 , pp. 485-500
    • Morgan, R.E.1    Trauner, M.2    van Staden, C.J.3    Lee, P.H.4    Ramachandran, B.5    Eschenberg, M.6
  • 12
    • 84455171488 scopus 로고    scopus 로고
    • In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans
    • Dawson S, Stahl S, Paul N, Barber J, Kenna JG. In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug Metab Dispos 2012; 40: 130-138.
    • (2012) Drug Metab Dispos , vol.40 , pp. 130-138
    • Dawson, S.1    Stahl, S.2    Paul, N.3    Barber, J.4    Kenna, J.G.5
  • 14
    • 84879606015 scopus 로고    scopus 로고
    • HLA-B*57:01-restricted activation of drug-specific T-cells provides the immunological basis for flucloxacillin-induced liver injury
    • Epub ahead of print.
    • Monshi M, Faulkner L, Gibson A, Jenkins RE, Farrell J, Earnshaw CJ, et al. HLA-B*57:01-restricted activation of drug-specific T-cells provides the immunological basis for flucloxacillin-induced liver injury. HEPATOLOGY 2012 [Epub ahead of print].
    • (2012) HEPATOLOGY
    • Monshi, M.1    Faulkner, L.2    Gibson, A.3    Jenkins, R.E.4    Farrell, J.5    Earnshaw, C.J.6
  • 15
    • 84863721147 scopus 로고    scopus 로고
    • Abacavir induces loading of novel self-peptides into HLA-B*57:01: an auto immune model for HLA-associated drug hypersensitivity
    • Norcross M, Luo S, Lu L, Boyne MT, Gomarteli M, Rennels AD, et al. Abacavir induces loading of novel self-peptides into HLA-B*57:01: an auto immune model for HLA-associated drug hypersensitivity. AIDS 2012; 26: F21-F29.
    • (2012) AIDS , vol.26
    • Norcross, M.1    Luo, S.2    Lu, L.3    Boyne, M.T.4    Gomarteli, M.5    Rennels, A.D.6
  • 16
    • 33746073706 scopus 로고    scopus 로고
    • Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis
    • Han D, Hanawa N, Saberi B, Kaplowitz N. Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis. Free Radic Biol Med 2006; 41: 627-639.
    • (2006) Free Radic Biol Med , vol.41 , pp. 627-639
    • Han, D.1    Hanawa, N.2    Saberi, B.3    Kaplowitz, N.4
  • 17
    • 35748961980 scopus 로고    scopus 로고
    • Glutathione depletion down-regulates TNFα-induced NF-kB activity via IKK-dependent and independent mechanisms
    • Lou H, Kaplowitz N. Glutathione depletion down-regulates TNFα-induced NF-kB activity via IKK-dependent and independent mechanisms. J Biol Chem 2007; 282: 29470-29481.
    • (2007) J Biol Chem , vol.282 , pp. 29470-29481
    • Lou, H.1    Kaplowitz, N.2
  • 18
    • 77955082302 scopus 로고    scopus 로고
    • A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
    • Singer JB, Lewitzky S, Leroy E, Yang F, Zhao X, Klickstein L, et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet 2010; 42: 711-714.
    • (2010) Nat Genet , vol.42 , pp. 711-714
    • Singer, J.B.1    Lewitzky, S.2    Leroy, E.3    Yang, F.4    Zhao, X.5    Klickstein, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.