Prevention of apoptosis averts glomerular tubular disconnection and podocyte loss in proteinuric kidney disease

Kidney International

Volumn 90, Issue 1, 2016, Pages 135-148

  Burlaka, Ievgeniia ^a   Nilsson, Linnéa M ^b   Scott, Lena ^a   Holtbäck, Ulla ^a   Eklöf, Ann Christine ^a   Fogo, Agnes B ^c   Brismar, Hjalmar ^a,b   Aperia, Anita ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

a tubular glomeruli; albuminuria; apoptosis; cell signaling; chronic kidney disease; ouabain; podocyte; proximal tubule; sodium potassium adenosine triphosphatase

Indexed keywords

ALBUMIN; COLLAGEN; OUABAIN; PROTEIN BAX; PROTEIN BCL XL; TRANSFORMING GROWTH FACTOR BETA1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BAX PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; CARDIOTONIC AGENT; PROTEIN BCL X;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL LOSS; CELL MEMBRANE DEPOLARIZATION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; EPITHELIUM CELL; GLOMERULAR TUBULAR DISCONNECTION; HEYMANN NEPHRITIS; KIDNEY DISEASE; KIDNEY FIBROSIS; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIC KIDNEY DISEASE; RAT; RENAL EPITHELIAL CELL; RENAL PROTECTION; UPREGULATION; ANIMAL; DRUG EFFECTS; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULUS; HUMAN; KIDNEY PROXIMAL TUBULE; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PRECLINICAL STUDY; PRIMARY CELL CULTURE; PROTEINURIA; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CARDIOTONIC AGENTS; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; GLOMERULONEPHRITIS, MEMBRANOUS; HUMANS; KIDNEY DISEASES; KIDNEY GLOMERULUS; KIDNEY TUBULES, PROXIMAL; MALE; OUABAIN; PODOCYTES; PRIMARY CELL CULTURE; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-POTASSIUM-EXCHANGING ATPASE; UP-REGULATION;

EID: 84988335957     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.03.026     Document Type: Article

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