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Volumn 24, Issue 9, 2013, Pages 1413-1423

Ouabain protects against shiga toxin-triggered apoptosis by reversing the imbalance between Bax and Bcl-xL

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; HELENALIN; OUABAIN; PROTEIN BAX; PROTEIN BCL XL; SHIGA TOXIN; TRANSCRIPTION FACTOR RELA; VEROTOXIN 2; VIRULENCE FACTOR;

EID: 84884297830     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012101044     Document Type: Article
Times cited : (35)

References (39)
  • 1
    • 79952087639 scopus 로고    scopus 로고
    • Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease
    • Obrig TG: Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease. Toxins (Basel) 2: 2769-2794, 2010
    • (2010) Toxins (Basel) , vol.2 , pp. 2769-2794
    • Obrig, T.G.1
  • 2
    • 77957588040 scopus 로고    scopus 로고
    • Pathophysiology of typical hemolytic uremic syndrome
    • Karpman D, Sartz L, Johnson S: Pathophysiology of typical hemolytic uremic syndrome. Semin Thromb Hemost 36: 575-585, 2010
    • (2010) Semin Thromb Hemost , vol.36 , pp. 575-585
    • Karpman, D.1    Sartz, L.2    Johnson, S.3
  • 7
    • 23344441474 scopus 로고    scopus 로고
    • Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism
    • Lee SY, Cherla RP, Caliskan I, Tesh VL: Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism. Infect Immun 73: 5115-5126, 2005
    • (2005) Infect Immun , vol.73 , pp. 5115-5126
    • Lee, S.Y.1    Cherla, R.P.2    Caliskan, I.3    Tesh, V.L.4
  • 9
    • 1442359881 scopus 로고    scopus 로고
    • Bcl-2 family members: Intracellular targeting, membrane-insertion, and changes in subcellular localization
    • Schinzel A, Kaufmann T, Borner C: Bcl-2 family members: Intracellular targeting, membrane-insertion, and changes in subcellular localization. Biochim Biophys Acta 1644: 95-105, 2004
    • (2004) Biochim Biophys Acta , vol.1644 , pp. 95-105
    • Schinzel, A.1    Kaufmann, T.2    Borner, C.3
  • 10
    • 0033828559 scopus 로고    scopus 로고
    • CD40 ligand, Bcl-2, and Bcl-xL spare group i Burkitt lymphoma cells from CD77-directed killing via Verotoxin-1 B chain but fail to protect against the holotoxin
    • Gordon J, Challa A, Levens JM,Gregory CD, Williams JM, Armitage RJ, Cook JP, Roberts LM, Lord JM: CD40 ligand, Bcl-2, and Bcl-xL spare group I Burkitt lymphoma cells from CD77-directed killing via Verotoxin-1 B chain but fail to protect against the holotoxin. Cell Death Differ 7: 785-794, 2000
    • (2000) Cell Death Differ , vol.7 , pp. 785-794
    • Gordon, J.1    Challa, A.2    Levens, J.M.3    Gregory, C.D.4    Williams, J.M.5    Armitage, R.J.6    Cook, J.P.7    Roberts, L.M.8    Lord, J.M.9
  • 12
    • 77957587756 scopus 로고    scopus 로고
    • Treatment of typical (enteropathic) hemolytic uremic syndrome
    • Bitzan M, Schaefer F, Reymond D: Treatment of typical (enteropathic) hemolytic uremic syndrome. Semin Thromb Hemost 36: 594-610, 2010
    • (2010) Semin Thromb Hemost , vol.36 , pp. 594-610
    • Bitzan, M.1    Schaefer, F.2    Reymond, D.3
  • 13
    • 84859341542 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome: New developments in pathogenesis and treatment
    • Boyer O, Niaudet P: Hemolytic uremic syndrome: New developments in pathogenesis and treatment. Int J Nephrol 2011: 908407, 2011
    • (2011) Int J Nephrol , vol.2011 , pp. 908407
    • Boyer, O.1    Niaudet, P.2
  • 14
    • 33846011388 scopus 로고    scopus 로고
    • New roles for an old enzyme: Na,K-ATPase emerges as an interesting drug target
    • Aperia A: New roles for an old enzyme: Na,K-ATPase emerges as an interesting drug target. J Intern Med 261: 44-52, 2007
    • (2007) J Intern Med , vol.261 , pp. 44-52
    • Aperia, A.1
  • 15
    • 33746839661 scopus 로고    scopus 로고
    • Distinct role of the N-terminal tail of the Na,K-ATPase catalytic subunit as a signal transducer
    • Zhang S, Malmersjö S, Li J, Ando H, Aizman O, Uhlén P, Mikoshiba K, Aperia A: Distinct role of the N-terminal tail of the Na,K-ATPase catalytic subunit as a signal transducer. J Biol Chem281: 21954-21962, 2006
    • (2006) J Biol Chem , vol.281 , pp. 21954-21962
    • Zhang, S.1    Malmersjö, S.2    Li, J.3    Ando, H.4    Aizman, O.5    Uhlén, P.6    Mikoshiba, K.7    Aperia, A.8
  • 16
    • 0346118913 scopus 로고    scopus 로고
    • Cell signalingmicrodomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations
    • Miyakawa-Naito A, Uhlén P, Lal M, Aizman O, Mikoshiba K, Brismar H, Zelenin S, Aperia A: Cell signalingmicrodomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations. J Biol Chem278: 50355-50361, 2003
    • (2003) J Biol Chem , vol.278 , pp. 50355-50361
    • Miyakawa-Naito, A.1    Uhlén, P.2    Lal, M.3    Aizman, O.4    Mikoshiba, K.5    Brismar, H.6    Zelenin, S.7    Aperia, A.8
  • 17
  • 18
    • 33745818598 scopus 로고    scopus 로고
    • Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activationofNF-kappaB
    • Li J, Zelenin S, Aperia A, Aizman O: Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activationofNF-kappaB.JAmSocNephrol 17: 1848-1857, 2006
    • (2006) JAmSocNephrol , vol.17 , pp. 1848-1857
    • Li, J.1    Zelenin, S.2    Aperia, A.3    Aizman, O.4
  • 20
    • 0345561544 scopus 로고    scopus 로고
    • Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons
    • Tamatani M, Che YH, Matsuzaoki H, Ogawa S, Okado H, Miyake S, Mizuno T, Tohyama M: Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J Biol Chem274: 8531-8538, 1999
    • (1999) J Biol Chem , vol.274 , pp. 8531-8538
    • Tamatani, M.1    Che, Y.H.2    Matsuzaoki, H.3    Ogawa, S.4    Okado, H.5    Miyake, S.6    Mizuno, T.7    Tohyama, M.8
  • 21
    • 33845243385 scopus 로고    scopus 로고
    • A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease
    • Keepers TR, Psotka MA, Gross LK, Obrig TG: A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease. J Am Soc Nephrol 17: 3404-3414, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3404-3414
    • Keepers, T.R.1    Psotka, M.A.2    Gross, L.K.3    Obrig, T.G.4
  • 22
    • 0023726625 scopus 로고
    • Dexamethasone-induced alterations in the glycosphingolipids of rat kidney
    • Dahiya R, Brasitus TA: Dexamethasone-induced alterations in the glycosphingolipids of rat kidney. Lipids 23: 863-868, 1988
    • (1988) Lipids , vol.23 , pp. 863-868
    • Dahiya, R.1    Brasitus, T.A.2
  • 25
    • 85190671618 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NFkappaB by directly targeting p65
    • 33508-335016
    • Lyss G, Knorre A, Schmidt TJ, Pahl HL,Merfort I: The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NFkappaB by directly targeting p65 J Biol Che 11: 273(50): 33508-335016, 1998.
    • (1998) J Biol Che , vol.11 , Issue.50 , pp. 273
    • Lyss, G.1    Knorre, A.2    Schmidt, T.J.3    Pahl, H.L.4    Merfort, I.5
  • 26
    • 0001112989 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NFkB by directly targeting p65
    • 33508-33516
    • LyßG, Knorre A, Schmidt TJ, Pahl HL,Merfort I: The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NFkB by directly targeting p65. J Biol Chem 273: 50: 33508-33516, 1998
    • (1998) J Biol Chem , vol.273 , pp. 50
    • Lyß, G.1    Knorre, A.2    Schmidt, T.J.3    Pahl, H.L.4    Merfort, I.5
  • 28
    • 53649099970 scopus 로고    scopus 로고
    • Mouse model of hemolytic-uremic syndrome caused by endotoxinfree Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody
    • Sauter KAD,Melton-Celsa AR, Larkin K, TroxellML,O'Brien AD,Magun BE:Mouse model of hemolytic-uremic syndrome caused by endotoxinfree Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody. Infect Immun 76: 4469-4478, 2008
    • (2008) Infect Immun , vol.76 , pp. 4469-4478
    • Sauter, K.A.D.1    Melton-Celsa, A.R.2    Larkin, K.3    Troxell, M.L.4    O'brien, A.D.5    Magun, B.E.6
  • 29
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • Elmore S: Apoptosis: A review of programmed cell death. Toxicol Pathol 35: 495-516, 2007
    • (2007) Toxicol Pathol , vol.35 , pp. 495-516
    • Elmore, S.1
  • 30
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer G, Galluzzi L, Brenner C: Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163, 2007
    • (2007) Physiol Rev , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 31
    • 77952290131 scopus 로고    scopus 로고
    • Intracerebroventricular Shiga toxin 2 increases the expression of its receptor globotriaosylceramide and causes dendritic abnormalities
    • Tironi-Farinati C, Loidl CF, Boccoli J, Parma Y, Fernandez-Miyakawa ME, Goldstein J: Intracerebroventricular Shiga toxin 2 increases the expression of its receptor globotriaosylceramide and causes dendritic abnormalities. J Neuroimmunol 222: 48-61, 2010
    • (2010) J Neuroimmunol , vol.222 , pp. 48-61
    • Tironi-Farinati, C.1    Loidl, C.F.2    Boccoli, J.3    Parma, Y.4    Fernandez-Miyakawa, M.E.5    Goldstein, J.6
  • 32
    • 0034663779 scopus 로고    scopus 로고
    • The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes
    • Khoshnan A, Tindell C, Laux I, Bae D, Bennett B, Nel AE: The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J Immunol 165: 1743-1754, 2000
    • (2000) J Immunol , vol.165 , pp. 1743-1754
    • Khoshnan, A.1    Tindell, C.2    Laux, I.3    Bae, D.4    Bennett, B.5    Nel, A.E.6
  • 33
    • 0037207471 scopus 로고    scopus 로고
    • Cell biology of the glomerular podocyte
    • Pavenstädt H, Kriz W, Kretzler M: Cell biology of the glomerular podocyte. Physiol Rev 83: 253-307, 2003
    • (2003) Physiol Rev , vol.83 , pp. 253-307
    • Pavenstädt, H.1    Kriz, W.2    Kretzler, M.3
  • 36
    • 39049085896 scopus 로고    scopus 로고
    • Generation and evolution of atubular glomeruli in theprogressionof renaldisorders
    • Chevalier RL, Forbes MS: Generation and evolution of atubular glomeruli in theprogressionof renaldisorders. JAmSocNephrol 19: 197-206, 2008
    • (2008) JAmSocNephrol , vol.19 , pp. 197-206
    • Chevalier, R.L.1    Forbes, M.S.2
  • 37
    • 0034642988 scopus 로고    scopus 로고
    • Reduced Pax2 gene dosage increases apoptosis and slows the progression of renal cystic disease
    • Ostrom L, Tang MJ, Gruss P, Dressler GR: Reduced Pax2 gene dosage increases apoptosis and slows the progression of renal cystic disease. Dev Biol 219: 250-258, 2000
    • (2000) Dev Biol , vol.219 , pp. 250-258
    • Ostrom, L.1    Tang, M.J.2    Gruss, P.3    Dressler, G.R.4


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