Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 37, 2016, Pages E5454-E5463

  Pageon, Sophie V ^a,b   Tabarin, Thibault ^a,b   Yamamoto, Yui ^a,b   Ma, Yuanqing ^a,b   Bridgeman, John S ^c,d   Cohnen, André ^e   Benzing, Carola ^a,b   Gao, Yijun ^a,b   Crowther, Michael D ^c   Tungatt, Katie ^c   Dolton, Garry ^c   Sewell, Andrew K ^c   Price, David A ^c,f   Acuto, Oreste ^e   Parton, Robert G ^g   Gooding, J Justin ^g,h   Rossy, Jérémie ^a,b   Rossjohn, Jamie ^c,i   Gaus, Katharina ^a,b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^d Cellular Therapeutics Ltd   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^g UNIVERSITY OF QUEENSLAND   (Australia)

^h UNIVERSITY OF NEW SOUTH WALES   (Australia)

ⁱ MONASH UNIVERSITY   (Australia)

Author keywords

Signal transduction; Single molecule localization microscopy; Tcr triggering

Indexed keywords

CD3 ANTIGEN; CD3 ZETA ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN RECOGNITION; COMPLEX FORMATION; CONFERENCE PAPER; CONTROLLED STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SINGLE MOLECULE LOCALIZATION MICROSCOPY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ADAPTIVE IMMUNITY; ANIMAL; GENETICS; HUMAN; IMMUNOLOGY; PHOSPHORYLATION; SINGLE MOLECULE IMAGING;

ADAPTIVE IMMUNITY; ANIMALS; ANTIGENS; CD3 COMPLEX; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; PEPTIDES; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SINGLE MOLECULE IMAGING;

EID: 84987667744     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1607436113     Document Type: Article

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