Environmental changes bridge evolutionary valleys

Science Advances

Volumn 2, Issue 1, 2016, Pages

  Steinberg, Barrett ^a,b   Ostermeier, Marc ^a  

^a Johns Hopkins University   (United States)

^b EDITAS MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; EVOLUTIONARY ALGORITHMS; GENES; MOLECULAR BIOLOGY;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC RESISTANCE GENES; ENVIRONMENTAL CHANGE; EVOLUTIONARY HISTORY; EVOLUTIONARY MECHANISMS; EVOLUTIONARY PATHWAY; EVOLUTIONARY STRATEGIES; MOLECULAR EVOLUTION;

DNA SEQUENCES;

ANTIINFECTIVE AGENT; BETA LACTAMASE; TEM-15 BETA-LACTAMASE;

ALLELE; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; ENVIRONMENT; EPISTASIS; ESCHERICHIA COLI; GENETIC SELECTION; GENETICS; MOLECULAR EVOLUTION; MUTATION; REPRODUCTIVE FITNESS;

ALLELES; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DRUG RESISTANCE, MICROBIAL; ENVIRONMENT; EPISTASIS, GENETIC; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENETIC FITNESS; MUTATION; SELECTION, GENETIC;

EID: 84987617523     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1500921     Document Type: Article

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