메뉴 건너뛰기




Volumn 537, Issue 7619, 2016, Pages 249-253

Insights from biochemical reconstitution into the architecture of human kinetochores

Author keywords

[No Author keywords available]

Indexed keywords

CENTROMERE PROTEIN A; CENTROMERE PROTEIN C; CENTROMERE PROTEIN N; CHIKMLN COMPLEX; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; AUTOANTIGEN; MULTIPROTEIN COMPLEX; NONHISTONE PROTEIN; NUCLEOSOME; PROTEIN SUBUNIT;

EID: 84986538938     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19333     Document Type: Article
Times cited : (125)

References (55)
  • 1
    • 84871530214 scopus 로고    scopus 로고
    • Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore
    • Foley, E. A., Kapoor, T. M. Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nature Rev. Mol. Cell Biol. 14, 25-37 (2013).
    • (2013) Nature Rev. Mol. Cell Biol. , vol.14 , pp. 25-37
    • Foley, E.A.1    Kapoor, T.M.2
  • 2
    • 84908218352 scopus 로고    scopus 로고
    • The centromere: Chromatin foundation for the kinetochore machinery
    • Fukagawa, T., Earnshaw, W. C. The centromere: chromatin foundation for the kinetochore machinery. Dev. Cell 30, 496-508 (2014).
    • (2014) Dev. Cell , vol.30 , pp. 496-508
    • Fukagawa, T.1    Earnshaw, W.C.2
  • 3
    • 33646740560 scopus 로고    scopus 로고
    • Comprehensive analysis of the ICEN (interphase centromere complex) components enriched in the CENP-A chromatin of human cells
    • Izuta, H. et al. Comprehensive analysis of the ICEN (interphase centromere complex) components enriched in the CENP-A chromatin of human cells. Genes Cells 11, 673-684 (2006).
    • (2006) Genes Cells , vol.11 , pp. 673-684
    • Izuta, H.1
  • 4
    • 33745004786 scopus 로고    scopus 로고
    • The human CENP-A centromeric nucleosome-associated complex
    • Foltz, D. R. et al. The human CENP-A centromeric nucleosome-associated complex. Nature Cell Biol. 8, 458-469 (2006).
    • (2006) Nature Cell Biol. , vol.8 , pp. 458-469
    • Foltz, D.R.1
  • 5
    • 57149129148 scopus 로고    scopus 로고
    • CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore
    • Hori, T. et al. CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore. Cell 135, 1039-1052 (2008).
    • (2008) Cell , vol.135 , pp. 1039-1052
    • Hori, T.1
  • 6
    • 33744970012 scopus 로고    scopus 로고
    • The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres
    • Okada, M. et al. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nature Cell Biol. 8, 446-457 (2006).
    • (2006) Nature Cell Biol. , vol.8 , pp. 446-457
    • Okada, M.1
  • 7
    • 33751227843 scopus 로고    scopus 로고
    • Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
    • DeLuca, J. G. et al. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 127, 969-982 (2006).
    • (2006) Cell , vol.127 , pp. 969-982
    • DeLuca, J.G.1
  • 8
    • 33751232957 scopus 로고    scopus 로고
    • The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
    • Cheeseman, I. M., Chappie, J. S., Wilson-Kubalek, E. M., Desai, A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127, 983-997 (2006).
    • (2006) Cell , vol.127 , pp. 983-997
    • Cheeseman, I.M.1    Chappie, J.S.2    Wilson-Kubalek, E.M.3    Desai, A.4
  • 9
    • 77954396194 scopus 로고    scopus 로고
    • Dual recognition of CENP-A nucleosomes is required for centromere assembly
    • Carroll, C. W., Milks, K. J., Straight, A. F. Dual recognition of CENP-A nucleosomes is required for centromere assembly. J. Cell Biol. 189, 1143-1155 (2010).
    • (2010) J. Cell Biol. , vol.189 , pp. 1143-1155
    • Carroll, C.W.1    Milks, K.J.2    Straight, A.F.3
  • 10
    • 67650065426 scopus 로고    scopus 로고
    • Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N
    • Carroll, C. W., Silva, M. C., Godek, K. M., Jansen, L. E., Straight, A. F. Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N. Nature Cell Biol. 11, 896-902 (2009).
    • (2009) Nature Cell Biol. , vol.11 , pp. 896-902
    • Carroll, C.W.1    Silva, M.C.2    Godek, K.M.3    Jansen, L.E.4    Straight, A.F.5
  • 11
    • 84878363880 scopus 로고    scopus 로고
    • A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C
    • Kato, H. et al. A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. Science 340, 1110-1113 (2013).
    • (2013) Science , vol.340 , pp. 1110-1113
    • Kato, H.1
  • 12
    • 84878149050 scopus 로고    scopus 로고
    • Family matters: Structural and functional conservation of centromere-associated proteins from yeast to humans
    • Westermann, S., Schleiffer, A. Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans. Trends Cell Biol. 23, 260-269 (2013).
    • (2013) Trends Cell Biol. , vol.23 , pp. 260-269
    • Westermann, S.1    Schleiffer, A.2
  • 13
    • 84908151071 scopus 로고    scopus 로고
    • Signalling dynamics in the spindle checkpoint response
    • London, N., Biggins, S. Signalling dynamics in the spindle checkpoint response. Nature Rev. Mol. Cell Biol. 15, 736-748 (2014).
    • (2014) Nature Rev. Mol. Cell Biol. , vol.15 , pp. 736-748
    • London, N.1    Biggins, S.2
  • 14
    • 84885977964 scopus 로고    scopus 로고
    • Anarchic centromeres: Deciphering order from apparent chaos
    • Catania, S., Allshire, R. C. Anarchic centromeres: deciphering order from apparent chaos. Curr. Opin. Cell Biol. 26, 41-50 (2014).
    • (2014) Curr. Opin. Cell Biol. , vol.26 , pp. 41-50
    • Catania, S.1    Allshire, R.C.2
  • 15
    • 84885852996 scopus 로고    scopus 로고
    • An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation
    • Hinshaw, S. M., Harrison, S. C. An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. Cell Reports 5, 29-36 (2013).
    • (2013) Cell Reports , vol.5 , pp. 29-36
    • Hinshaw, S.M.1    Harrison, S.C.2
  • 16
    • 0032512794 scopus 로고    scopus 로고
    • New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning
    • Lowary, P. T., Widom, J. New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning. J. Mol. Biol. 276, 19-42 (1998).
    • (1998) J. Mol. Biol. , vol.276 , pp. 19-42
    • Lowary, P.T.1    Widom, J.2
  • 17
    • 84945907177 scopus 로고    scopus 로고
    • Dynamic changes in CCAN organization through CENP-C during cell-cycle progression
    • Nagpal, H. et al. Dynamic changes in CCAN organization through CENP-C during cell-cycle progression. Mol. Biol. Cell 26, 3768-3776 (2015).
    • (2015) Mol. Biol. Cell , vol.26 , pp. 3768-3776
    • Nagpal, H.1
  • 18
    • 84953638894 scopus 로고    scopus 로고
    • The CENP-L-N complex forms a critical node in an integrated meshwork of interactions at the centromere-kinetochore interface
    • McKinley, K. L. et al. The CENP-L-N complex forms a critical node in an integrated meshwork of interactions at the centromere-kinetochore interface. Mol. Cell 60, 886-898 (2015).
    • (2015) Mol. Cell , vol.60 , pp. 886-898
    • McKinley, K.L.1
  • 19
    • 84904052265 scopus 로고    scopus 로고
    • The pseudo GTPase CENP-M drives human kinetochore assembly
    • Basilico, F. et al. The pseudo GTPase CENP-M drives human kinetochore assembly. eLife 3, e02978 (2014).
    • (2014) ELife , vol.3 , pp. e02978
    • Basilico, F.1
  • 20
    • 84945921601 scopus 로고    scopus 로고
    • CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores
    • Klare, K. et al. CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores. J. Cell Biol. 210, 11-22 (2015).
    • (2015) J. Cell Biol. , vol.210 , pp. 11-22
    • Klare, K.1
  • 21
    • 84866095385 scopus 로고    scopus 로고
    • Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry
    • Herzog, F. et al. Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry. Science 337, 1348-1352 (2012).
    • (2012) Science , vol.337 , pp. 1348-1352
    • Herzog, F.1
  • 22
    • 79955539577 scopus 로고    scopus 로고
    • Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes
    • Gascoigne, K. E. et al. Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes. Cell 145, 410-422 (2011).
    • (2011) Cell , vol.145 , pp. 410-422
    • Gascoigne, K.E.1
  • 23
    • 43049146221 scopus 로고    scopus 로고
    • Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex
    • Ciferri, C. et al. Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133, 427-439 (2008).
    • (2008) Cell , vol.133 , pp. 427-439
    • Ciferri, C.1
  • 24
    • 84861637392 scopus 로고    scopus 로고
    • CENP-T proteins are conserved centromere receptors of the Ndc80 complex
    • Schleiffer, A. et al. CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nature Cell Biol. 14, 604-613 (2012).
    • (2012) Nature Cell Biol. , vol.14 , pp. 604-613
    • Schleiffer, A.1
  • 25
    • 84941047044 scopus 로고    scopus 로고
    • A quantitative description of Ndc80 complex linkage to human kinetochores
    • Suzuki, A., Badger, B. L., Salmon, E. D. A quantitative description of Ndc80 complex linkage to human kinetochores. Nature Commun. 6, 8161 (2015).
    • (2015) Nature Commun. , vol.6 , pp. 8161
    • Suzuki, A.1    Badger, B.L.2    Salmon, E.D.3
  • 26
    • 84904431218 scopus 로고    scopus 로고
    • The quantitative architecture of centromeric chromatin
    • Bodor, D. L. et al. The quantitative architecture of centromeric chromatin. eLife 3, e02137 (2014).
    • (2014) ELife , vol.3 , pp. e02137
    • Bodor, D.L.1
  • 27
    • 84864205633 scopus 로고    scopus 로고
    • The split personality of CENP-A nucleosomes
    • Westhorpe, F. G., Straight, A. F. The split personality of CENP-A nucleosomes. Cell 150, 245-247 (2012).
    • (2012) Cell , vol.150 , pp. 245-247
    • Westhorpe, F.G.1    Straight, A.F.2
  • 28
    • 84866069395 scopus 로고    scopus 로고
    • The structure of purified kinetochores reveals multiple microtubule-attachment sites
    • Gonen, S. et al. The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nature Struct. Mol. Biol. 19, 925-929 (2012).
    • (2012) Nature Struct. Mol. Biol. , vol.19 , pp. 925-929
    • Gonen, S.1
  • 29
    • 78649476255 scopus 로고    scopus 로고
    • Tension directly stabilizes reconstituted kinetochoremicrotubule attachments
    • Akiyoshi, B. et al. Tension directly stabilizes reconstituted kinetochoremicrotubule attachments. Nature 468, 576-579 (2010).
    • (2010) Nature , vol.468 , pp. 576-579
    • Akiyoshi, B.1
  • 30
    • 80052849224 scopus 로고    scopus 로고
    • In vitro centromere and kinetochore assembly on defined chromatin templates
    • Guse, A., Carroll, C. W., Moree, B., Fuller, C. J., Straight, A. F. In vitro centromere and kinetochore assembly on defined chromatin templates. Nature 477, 354-358 (2011).
    • (2011) Nature , vol.477 , pp. 354-358
    • Guse, A.1    Carroll, C.W.2    Moree, B.3    Fuller, C.J.4    Straight, A.F.5
  • 31
    • 84856690548 scopus 로고    scopus 로고
    • MultiBac: Expanding the research toolbox for multiprotein complexes
    • Bieniossek, C., Imasaki, T., Takagi, Y., Berger, I. MultiBac: expanding the research toolbox for multiprotein complexes. Trends Biochem. Sci. 37, 49-57 (2012).
    • (2012) Trends Biochem. Sci. , vol.37 , pp. 49-57
    • Bieniossek, C.1    Imasaki, T.2    Takagi, Y.3    Berger, I.4
  • 32
    • 84859928855 scopus 로고    scopus 로고
    • Correction: BTI-Tnao38, a new cell line derived from Trichoplusia ni, is permissive for AcMNPV infection and produces high levels of recombinant proteins
    • Hashimoto, Y., Zhang, S., Zhang, S., Chen, Y. R., Blissard, G. W. Correction: BTI-Tnao38, a new cell line derived from Trichoplusia ni, is permissive for AcMNPV infection and produces high levels of recombinant proteins. BMC Biotechnol. 12, 12 (2012).
    • (2012) BMC Biotechnol. , vol.12 , pp. 12
    • Hashimoto, Y.1    Zhang, S.2    Zhang, S.3    Chen, Y.R.4    Blissard, G.W.5
  • 33
    • 1542334851 scopus 로고    scopus 로고
    • Reconstitution of nucleosome core particles from recombinant histones and DNA
    • Dyer, P. N. et al. Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods Enzymol. 375, 23-44 (2004).
    • (2004) Methods Enzymol. , vol.375 , pp. 23-44
    • Dyer, P.N.1
  • 34
    • 84870051852 scopus 로고    scopus 로고
    • A cell-free system for functional centromere and kinetochore assembly
    • Guse, A., Fuller, C. J., Straight, A. F. A cell-free system for functional centromere and kinetochore assembly. Nature Protocols 7, 1847-1869 (2012).
    • (2012) Nature Protocols , vol.7 , pp. 1847-1869
    • Guse, A.1    Fuller, C.J.2    Straight, A.F.3
  • 35
    • 84863084595 scopus 로고    scopus 로고
    • Polycistronic coexpression and nondenaturing purification of histone octamers
    • Shim, Y., Duan, M. R., Chen, X., Smerdon, M. J., Min, J. H. Polycistronic coexpression and nondenaturing purification of histone octamers. Anal. Biochem. 427, 190-192 (2012).
    • (2012) Anal. Biochem. , vol.427 , pp. 190-192
    • Shim, Y.1    Duan, M.R.2    Chen, X.3    Smerdon, M.J.4    Min, J.H.5
  • 36
    • 67349270900 scopus 로고    scopus 로고
    • Enzymatic assembly of DNA molecules up to several hundred kilobases
    • Gibson, D. G. et al. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nature Methods 6, 343-345 (2009).
    • (2009) Nature Methods , vol.6 , pp. 343-345
    • Gibson, D.G.1
  • 37
    • 84979856632 scopus 로고    scopus 로고
    • XVis: A web server for the schematic visualization and interpretation of crosslink-derived spatial restraints
    • Grimm, M., Zimniak, T., Kahraman, A., Herzog, F. xVis: a web server for the schematic visualization and interpretation of crosslink-derived spatial restraints. Nucleic Acids Res. 43 (W1), W362-W369 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , Issue.W1 , pp. W362-W369
    • Grimm, M.1    Zimniak, T.2    Kahraman, A.3    Herzog, F.4
  • 38
    • 33744809773 scopus 로고    scopus 로고
    • Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation
    • Brown, P. H., Schuck, P. Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation. Biophys. J. 90, 4651-4661 (2006).
    • (2006) Biophys. J. , vol.90 , pp. 4651-4661
    • Brown, P.H.1    Schuck, P.2
  • 39
    • 3242884785 scopus 로고    scopus 로고
    • Structural determinants for generating centromeric chromatin
    • Black, B. E. et al. Structural determinants for generating centromeric chromatin. Nature 430, 578-582 (2004).
    • (2004) Nature , vol.430 , pp. 578-582
    • Black, B.E.1
  • 40
    • 79952360863 scopus 로고    scopus 로고
    • CENP-C is a structural platform for kinetochore assembly
    • Przewloka, M. R. et al. CENP-C is a structural platform for kinetochore assembly. Curr. Biol. 21, 399-405 (2011).
    • (2011) Curr. Biol. , vol.21 , pp. 399-405
    • Przewloka, M.R.1
  • 41
    • 79952364478 scopus 로고    scopus 로고
    • Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore
    • Screpanti, E. et al. Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. Curr. Biol. 21, 391-398 (2011).
    • (2011) Curr. Biol. , vol.21 , pp. 391-398
    • Screpanti, E.1
  • 42
    • 55349136473 scopus 로고    scopus 로고
    • Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein
    • Cohen, R. L. et al. Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein. Mol. Biol. Cell 19, 4480-4491 (2008).
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4480-4491
    • Cohen, R.L.1
  • 43
    • 84860201576 scopus 로고    scopus 로고
    • CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin
    • Dambacher, S. et al. CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin. Nucleus 3, 101-110 (2012).
    • (2012) Nucleus , vol.3 , pp. 101-110
    • Dambacher, S.1
  • 44
    • 70350234658 scopus 로고    scopus 로고
    • Dissection of CENP-C-directed centromere and kinetochore assembly
    • Milks, K. J., Moree, B., Straight, A. F. Dissection of CENP-C-directed centromere and kinetochore assembly. Mol. Biol. Cell 20, 4246-4255 (2009).
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4246-4255
    • Milks, K.J.1    Moree, B.2    Straight, A.F.3
  • 45
    • 33846100785 scopus 로고    scopus 로고
    • The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment
    • Wei, R. R., Al-Bassam, J., Harrison, S. C. The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nature Struct. Mol. Biol. 14, 54-59 (2007).
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 54-59
    • Wei, R.R.1    Al-Bassam, J.2    Harrison, S.C.3
  • 46
    • 77949755046 scopus 로고    scopus 로고
    • Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes
    • Kiyomitsu, T., Iwasaki, O., Obuse, C., Yanagida, M. Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes. J. Cell Biol. 188, 791-807 (2010).
    • (2010) J. Cell Biol. , vol.188 , pp. 791-807
    • Kiyomitsu, T.1    Iwasaki, O.2    Obuse, C.3    Yanagida, M.4
  • 47
    • 84894260637 scopus 로고    scopus 로고
    • Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization
    • Petrovic, A. et al. Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization. Mol. Cell 53, 591-605 (2014).
    • (2014) Mol. Cell , vol.53 , pp. 591-605
    • Petrovic, A.1
  • 48
    • 78650856481 scopus 로고    scopus 로고
    • Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex
    • Hornung, P. et al. Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. J. Mol. Biol. 405, 548-559 (2011).
    • (2011) J. Mol. Biol. , vol.405 , pp. 548-559
    • Hornung, P.1
  • 49
    • 77956378429 scopus 로고    scopus 로고
    • The MIS12 complex is a protein interaction hub for outer kinetochore assembly
    • Petrovic, A. et al. The MIS12 complex is a protein interaction hub for outer kinetochore assembly. J. Cell Biol. 190, 835-852 (2010).
    • (2010) J. Cell Biol. , vol.190 , pp. 835-852
    • Petrovic, A.1
  • 50
    • 77956361304 scopus 로고    scopus 로고
    • Molecular architecture and assembly of the yeast kinetochore MIND complex
    • Maskell, D. P., Hu, X. W., Singleton, M. R. Molecular architecture and assembly of the yeast kinetochore MIND complex. J. Cell Biol. 190, 823-834 (2010).
    • (2010) J. Cell Biol. , vol.190 , pp. 823-834
    • Maskell, D.P.1    Hu, X.W.2    Singleton, M.R.3
  • 52
    • 80053934686 scopus 로고    scopus 로고
    • CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly
    • Moree, B., Meyer, C. B., Fuller, C. J., Straight, A. F. CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly. J. Cell Biol. 194, 855-871 (2011).
    • (2011) J. Cell Biol. , vol.194 , pp. 855-871
    • Moree, B.1    Meyer, C.B.2    Fuller, C.J.3    Straight, A.F.4
  • 53
    • 4544275776 scopus 로고    scopus 로고
    • Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres
    • Hayashi, T. et al. Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell 118, 715-729 (2004).
    • (2004) Cell , vol.118 , pp. 715-729
    • Hayashi, T.1
  • 54
    • 33947274529 scopus 로고    scopus 로고
    • Propagation of centromeric chromatin requires exit from mitosis
    • Jansen, L. E., Black, B. E., Foltz, D. R., Cleveland, D. W. Propagation of centromeric chromatin requires exit from mitosis. J. Cell Biol. 176, 795-805 (2007).
    • (2007) J. Cell Biol. , vol.176 , pp. 795-805
    • Jansen, L.E.1    Black, B.E.2    Foltz, D.R.3    Cleveland, D.W.4
  • 55
    • 84855956123 scopus 로고    scopus 로고
    • H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G1 phase
    • Dunleavy, E. M., Almouzni, G., Karpen, G. H. H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G1 phase. Nucleus 2, 146-157 (2011).
    • (2011) Nucleus , vol.2 , pp. 146-157
    • Dunleavy, E.M.1    Almouzni, G.2    Karpen, G.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.