Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore

Current Biology

Volumn 21, Issue 5, 2011, Pages 391-398

  Screpanti, Emanuela ^a   De Antoni, Anna ^a   Alushin, Gregory M ^b   Petrovic, Arsen ^a   Melis, Tiziana ^a   Nogales, Eva ^b,c   Musacchio, Andrea ^a,d  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CENTROMERE PROTEIN C; GREEN FLUORESCENT PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MIS12 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; NONHISTONE PROTEIN;

ARTICLE; CENTROMERE; CHROMOSOME SEGREGATION; ELECTRON MICROSCOPY; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GEL CHROMATOGRAPHY; GENETICS; HELA CELL; HUMAN; IMAGE PROCESSING; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS;

CHROMATOGRAPHY, GEL; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOBLOTTING; KINETOCHORES; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; MULTIPROTEIN COMPLEXES; PLASMIDS;

EID: 79952364478     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.12.039     Document Type: Article

References (40)

1. S. Santaguida, and A. Musacchio The life and miracles of kinetochores EMBO J. 28 2009 2511 2531
2. S. Trazzi, R. Bernardoni, D. Diolaiti, V. Politi, W.C. Earnshaw, G. Perini, and G. Della Valle In vivo functional dissection of human inner kinetochore protein CENP-C J. Struct. Biol. 140 2002 39 48 (Pubitemid 36139845)
3. S. Trazzi, G. Perini, R. Bernardoni, M. Zoli, J.C. Reese, A. Musacchio, and G. Della Valle The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation PLoS ONE 4 2009 e5832
4. R.L. Cohen, C.W. Espelin, P. De Wulf, P.K. Sorger, S.C. Harrison, and K.T. Simons Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein Mol. Biol. Cell 19 2008 4480 4491
5. C.W. Carroll, K.J. Milks, and A.F. Straight Dual recognition of CENP-A nucleosomes is required for centromere assembly J. Cell Biol. 189 2010 1143 1155
6. K. Song, B. Gronemeyer, W. Lu, E. Eugster, and J.E. Tomkiel Mutational analysis of the central centromere targeting domain of human centromere protein C, (CENP-C) Exp. Cell Res. 275 2002 81 91
7. P.B. Meluh, and D. Koshland Budding yeast centromere composition and assembly as revealed by in vivo cross-linking Genes Dev. 11 1997 3401 3412 (Pubitemid 28023962)
8. K. Sugimoto, H. Yata, Y. Muro, and M. Himeno Human centromere protein C (CENP-C) is a DNA-binding protein which possesses a novel DNA-binding motif J. Biochem. 116 1994 877 881 (Pubitemid 24323672)
9. C.H. Yang, J. Tomkiel, H. Saitoh, D.H. Johnson, and W.C. Earnshaw Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetochore protein CENP-C Mol. Cell. Biol. 16 1996 3576 3586 (Pubitemid 26199877)
10. L. Lanini, and F. McKeon Domains required for CENP-C assembly at the kinetochore Mol. Biol. Cell 6 1995 1049 1059
11. C.W. Carroll, M.C. Silva, K.M. Godek, L.E. Jansen, and A.F. Straight Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N Nat. Cell Biol. 11 2009 896 902
12. H. Saitoh, J. Tomkiel, C.A. Cooke, H. Ratrie 3rd, M. Maurer, N.F. Rothfield, and W.C. Earnshaw CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate Cell 70 1992 115 125
13. I.M. Cheeseman, S. Niessen, S. Anderson, F. Hyndman, J.R. Yates 3rd, K. Oegema, and A. Desai A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension Genes Dev. 18 2004 2255 2268 (Pubitemid 39209574)
14. S. Westermann, I.M. Cheeseman, S. Anderson, J.R. Yates 3rd, D.G. Drubin, and G. Barnes Architecture of the budding yeast kinetochore reveals a conserved molecular core J. Cell Biol. 163 2003 215 222 (Pubitemid 37363122)
15. P. De Wulf, A.D. McAinsh, and P.K. Sorger Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes Genes Dev. 17 2003 2902 2921 (Pubitemid 37523155)
16. B.A. Pinsky, S.Y. Tatsutani, K.A. Collins, and S. Biggins An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase Dev. Cell 5 2003 735 745 (Pubitemid 37362217)
17. A. Desai, S. Rybina, T. Müller-Reichert, A. Shevchenko, A. Shevchenko, A. Hyman, and K. Oegema KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans Genes Dev. 17 2003 2421 2435 (Pubitemid 37214790)
18. K.J. Milks, B. Moree, and A.F. Straight Dissection of CENP-C-directed centromere and kinetochore assembly Mol. Biol. Cell 20 2009 4246 4255
19. S.T. Liu, J.B. Rattner, S.A. Jablonski, and T.J. Yen Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells J. Cell Biol. 175 2006 41 53 (Pubitemid 44537197)
20. M.S. Kwon, T. Hori, M. Okada, and T. Fukagawa CENP-C is involved in chromosome segregation, mitotic checkpoint function, and kinetochore assembly Mol. Biol. Cell 18 2007 2155 2168 (Pubitemid 46911367)
21. M.R. Przewloka, W. Zhang, P. Costa, V. Archambault, P.P. D'Avino, K.S. Lilley, E.D. Laue, A.D. McAinsh, and D.M. Glover Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster PLoS ONE 2 2007 e478
22. B. Orr, and C.E. Sunkel Drosophila CENP-C is essential for centromere identity Chromosoma 120 2011 83 96
23. K. Tanaka, H.L. Chang, A. Kagami, and Y. Watanabe CENP-C functions as a scaffold for effectors with essential kinetochore functions in mitosis and meiosis Dev. Cell 17 2009 334 343
24. C. Ciferri, S. Pasqualato, E. Screpanti, G. Varetti, S. Santaguida, G. Dos Reis, A. Maiolica, J. Polka, J.G. De Luca, and P. De Wulf Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex Cell 133 2008 427 439 (Pubitemid 351622013)
25. A. Petrovic, S. Pasqualato, P. Dube, V. Krenn, S. Santaguida, D. Cittaro, S. Monzani, L. Massimiliano, J. Keller, and A. Tarricone The MIS12 complex is a protein interaction hub for outer kinetochore assembly J. Cell Biol. 190 2010 835 852
26. K. Johnston, A. Joglekar, T. Hori, A. Suzuki, T. Fukagawa, and E.D. Salmon Vertebrate kinetochore protein architecture: Protein copy number J. Cell Biol. 189 2010 937 943
27. A.D. McAinsh, P. Meraldi, V.M. Draviam, A. Toso, and P.K. Sorger The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation EMBO J. 25 2006 4033 4049 (Pubitemid 44338745)
28. A.P. Joglekar, K. Bloom, and E.D. Salmon In vivo protein architecture of the eukaryotic kinetochore with nanometer scale accuracy Curr. Biol. 19 2009 694 699
29. R.B. Schittenhelm, S. Heeger, F. Althoff, A. Walter, S. Heidmann, K. Mechtler, and C.F. Lehner Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes Chromosoma 116 2007 385 402 (Pubitemid 46995577)
30. X. Wan, R.P. O'Quinn, H.L. Pierce, A.P. Joglekar, W.E. Gall, J.G. DeLuca, C.W. Carroll, S.T. Liu, T.J. Yen, and B.F. McEwen Protein architecture of the human kinetochore microtubule attachment site Cell 137 2009 672 684
31. M.R. Przewloka, Z. Venkei, V.M. Bolanos-Garcia, J. Debski, M. Dadlez, and D.M. Glover CENP-C is a structural platform for kinetochore assembly Curr. Biol. 20 2011 399 405 this issue
32. S.L. Kline, I.M. Cheeseman, T. Hori, T. Fukagawa, and A. Desai The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation J. Cell Biol. 173 2006 9 17
33. I.M. Cheeseman, T. Hori, T. Fukagawa, and A. Desai KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates Mol. Biol. Cell 19 2008 587 594 (Pubitemid 351272147)
34. T. Kiyomitsu, C. Obuse, and M. Yanagida Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1 Dev. Cell 13 2007 663 676 (Pubitemid 350019284)
35. T. Hori, M. Okada, K. Maenaka, and T. Fukagawa CENP-O class proteins form a stable complex and are required for proper kinetochore function Mol. Biol. Cell 19 2008 843 854 (Pubitemid 351481802)
36. T. Hori, M. Amano, A. Suzuki, C.B. Backer, J.P. Welburn, Y. Dong, B.F. McEwen, W.H. Shang, E. Suzuki, and K. Okawa CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore Cell 135 2008 1039 1052
37. G. Vader, and S.M. Lens Chromosome segregation: Taking the passenger seat Curr. Biol. 20 2010 R879 R881
38. T. Kiyomitsu, O. Iwasaki, C. Obuse, and M. Yanagida Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes J. Cell Biol. 188 2010 791 807
39. D.P. Maskell, X.W. Hu, and M.R. Singleton Molecular architecture and assembly of the yeast kinetochore MIND complex J. Cell Biol. 190 2010 823 834
40. P. Hornung, M. Maier, G.M. Alushin, G.C. Lander, E. Nogales, and S. Westermann Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex J. Mol. Biol. 405 2011 548 559