G-actin provides substrate-specificity to eukaryotic initiation factor2α holophosphatases

eLife

Volumn 2015, Issue 4, 2015, Pages

  Chen, Ruming ^a   Rato, Cláudia ^a   Yan, Yahui ^a   Crespillo Casado, Ana ^a   Clarke, Hanna J ^a   Harding, Heather P ^a   Marciniak, Stefan J ^a   Read, Randy J ^a   Ron, David ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b INSTITUTE OF METABOLIC SCIENCE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

G ACTIN; GLUTATHIONE TRANSFERASE; GLYCOGEN PHOSPHORYLASE; HOLOPHOSPHATASE; INITIATION FACTOR 2ALPHA; PLASMID VECTOR; UNCLASSIFIED DRUG; ACTIN; INITIATION FACTOR 2; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHINESE HAMSTER; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; FLOW CYTOMETRY; GEL PERMEATION CHROMATOGRAPHY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; MOLECULAR DOCKING; MUTAGENESIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; STRESS; X RAY DIFFRACTION; AMINO ACID SEQUENCE; ANIMAL; BOVINE; CHEMICAL STRUCTURE; CHO CELL LINE; CONSERVED SEQUENCE; CRICETULUS; GENETICS; HAMSTER; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PHOSPHORYLATION; RABBIT;

EUKARYOTA;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CATTLE; CHO CELLS; CONSERVED SEQUENCE; CRICETINAE; CRICETULUS; EUKARYOTIC INITIATION FACTOR-2; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; RABBITS; SUBSTRATE SPECIFICITY;

EID: 84984871098     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.04871     Document Type: Article

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