Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zhou, Qian ^a   Chen, Bin ^b   Wang, Xindong ^a   Wu, Lixin ^a   Yang, Yang ^a,c   Cheng, Xiaolan ^a,c   Hu, Zhengli ^a   Cai, Xueting ^a,c   Yang, Jie ^a,c   Sun, Xiaoyan ^a,c   Lu, Wuguang ^a,c   Yan, Huaijiang ^a,c   Chen, Jiao ^a,c   Ye, Juan ^a,c   Shen, Jianping ^a   Cao, Peng ^a,c  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Nanjing Institute for Comprehensive Utilization of Wild Plant   (China)

^c Jiangsu Province Academy of Traditional Chinese Medicine   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; ISOTHIOCYANIC ACID DERIVATIVE; MTOR PROTEIN, MOUSE; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; ROTENONE; SULFORAFAN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; AUTOPHAGY; BAGG ALBINO MOUSE; CELL LINE; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DRUG EFFECT; HUMAN; MALE; METABOLISM; PARKINSON DISEASE; PATHOLOGY; TOXICITY AND INTOXICATION;

ANIMALS; AUTOPHAGY; CELL LINE; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; GLUTATHIONE; HUMANS; ISOTHIOCYANATES; MALE; MICE, INBRED BALB C; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; NF-E2-RELATED FACTOR 2; PARKINSON DISEASE; ROTENONE; TOR SERINE-THREONINE KINASES;

EID: 84984677275     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep32206     Document Type: Article

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