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Volumn 9, Issue 7, 2014, Pages

Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease models

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; SALVIANOLIC ACID B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; 1 METHYL 4 PHENYLPYRIDINIUM; BENZOFURAN DERIVATIVE; CYTOKINE; GDNF PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; NFE2L2 PROTEIN, MOUSE;

EID: 84903761080     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101668     Document Type: Article
Times cited : (57)

References (62)
  • 2
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • DOI 10.1016/S0896-6273(03)00568-3
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39: 889-909. (Pubitemid 37130207)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 3
    • 0032497504 scopus 로고    scopus 로고
    • Parkinson's disease
    • DOI 10.1056/NEJM199810083391506
    • Lang AE, Lozano AM(1998) Parkinson's disease. First of two parts. N Engl J Med 339: 1044-1053. (Pubitemid 28457867)
    • (1998) New England Journal of Medicine , vol.339 , Issue.15 , pp. 1044-1053
    • Lang, A.E.1    Lozano, A.M.2
  • 4
    • 68649126582 scopus 로고    scopus 로고
    • Targets for neuroprotection in Parkinson's disease
    • Yacoubian TA, Standaert DG (2009) Targets for neuroprotection in Parkinson's disease. Biochim Biophys Acta 1792: 676-687.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 676-687
    • Yacoubian, T.A.1    Standaert, D.G.2
  • 6
    • 77955105496 scopus 로고    scopus 로고
    • Astrocytes control breathing through pH-dependent release of ATP
    • Gourine AV, Kasymov V, Marina N, Tang F, Figueiredo MF, et al. (2010) Astrocytes control breathing through pH-dependent release of ATP. Science 329: 571-575.
    • (2010) Science , vol.329 , pp. 571-575
    • Gourine, A.V.1    Kasymov, V.2    Marina, N.3    Tang, F.4    Figueiredo, M.F.5
  • 7
    • 50549099422 scopus 로고    scopus 로고
    • D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration
    • Wolosker H, Dumin E, Balan L, Foltyn VN (2008) D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration. FEBS J 275: 3514-3526.
    • (2008) FEBS J , vol.275 , pp. 3514-3526
    • Wolosker, H.1    Dumin, E.2    Balan, L.3    Foltyn, V.N.4
  • 8
    • 70350346842 scopus 로고    scopus 로고
    • The influence of microglia on the pathogenesis of Parkinson's disease
    • Long-Smith CM, Sullivan AM, Nolan YM (2009) The influence of microglia on the pathogenesis of Parkinson's disease. Prog Neurobiol 89: 277-287.
    • (2009) Prog Neurobiol , vol.89 , pp. 277-287
    • Long-Smith, C.M.1    Sullivan, A.M.2    Nolan, Y.M.3
  • 9
    • 33748447845 scopus 로고    scopus 로고
    • Microglia, major player in the brain inflammation: The roles in the pathogenesis of Parkinson's disease
    • Kim YS, Joh TH (2006) Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease. Exp Mol Med 38: 333-347. (Pubitemid 44390511)
    • (2006) Journal of the Chinese Medical Association , vol.38 , Issue.4 , pp. 333-347
    • Kim, Y.S.1    Joh, T.H.2
  • 10
    • 14844311296 scopus 로고    scopus 로고
    • Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
    • Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, et al. (2005) Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 102: 216-222. (Pubitemid 43194069)
    • (2005) Journal of Neurosurgery , vol.102 , Issue.2 , pp. 216-222
    • Slevin, J.T.1    Gerhardt, G.A.2    Smith, C.D.3    Gash, D.M.4    Kryscio, R.5    Young, B.6
  • 11
    • 80955179603 scopus 로고    scopus 로고
    • Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GDNF in astroglia
    • corrected
    • Ossola B, Schendzielorz N, Chen SH, Bird GS, Tuominen RK, et al. (2011) Amantadine protects dopamine neurons by a dual action: reducing activation of microglia and inducing expression of GDNF in astroglia [corrected]. Neuropharmacology 61: 574-582.
    • (2011) Neuropharmacology , vol.61 , pp. 574-582
    • Ossola, B.1    Schendzielorz, N.2    Chen, S.H.3    Bird, G.S.4    Tuominen, R.K.5
  • 12
    • 84862749712 scopus 로고    scopus 로고
    • Current progress of research on pharmacologic actions of salvianolic acid B
    • Cao W, Guo XW, Zheng HZ, Li DP, Jia GB, et al. (2012) Current progress of research on pharmacologic actions of salvianolic acid B. Chin J Integr Med 18: 316-320.
    • (2012) Chin J Integr Med , vol.18 , pp. 316-320
    • Cao, W.1    Guo, X.W.2    Zheng, H.Z.3    Li, D.P.4    Jia, G.B.5
  • 13
    • 0036628715 scopus 로고    scopus 로고
    • Effect of salvianolic acids from Radix Salviae miltiorrhizae on regional cerebral blood flow and platelet aggregation in rats
    • Tang MK, Ren DC, Zhang JT, Du GH (2002) Effect of salvianolic acids from Radix Salviae miltiorrhizae on regional cerebral blood flow and platelet aggregation in rats. Phytomedicine 9: 405-409.
    • (2002) Phytomedicine , vol.9 , pp. 405-409
    • Tang, M.K.1    Ren, D.C.2    Zhang, J.T.3    Du, G.H.4
  • 14
    • 79251607360 scopus 로고    scopus 로고
    • Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer
    • Zhao Y, Guo Y, Gu X (2011) Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer. J Oncol 2011: 534548.
    • (2011) J Oncol , vol.2011 , pp. 534548
    • Zhao, Y.1    Guo, Y.2    Gu, X.3
  • 15
    • 84885181935 scopus 로고    scopus 로고
    • Salvianolic acid B induces apoptosis in human glioma U87 cells through p38-mediated ROS generation
    • Wang ZS, Luo P, Dai SH, Liu ZB, Zheng XR, et al. (2013) Salvianolic acid B induces apoptosis in human glioma U87 cells through p38-mediated ROS generation. Cell Mol Neurobiol 33: 921-928.
    • (2013) Cell Mol Neurobiol , vol.33 , pp. 921-928
    • Wang, Z.S.1    Luo, P.2    Dai, S.H.3    Liu, Z.B.4    Zheng, X.R.5
  • 16
    • 82355181067 scopus 로고    scopus 로고
    • Salvianolic acid B suppresses IFN-gamma-induced JAK/STAT1 activation in endothelial cells
    • Chen SC, Lin YL, Huang B, Wang DL, Cheng JJ (2011) Salvianolic acid B suppresses IFN-gamma-induced JAK/STAT1 activation in endothelial cells. Thromb Res 128: 560-564.
    • (2011) Thromb Res , vol.128 , pp. 560-564
    • Chen, S.C.1    Lin, Y.L.2    Huang, B.3    Wang, D.L.4    Cheng, J.J.5
  • 17
    • 79451471769 scopus 로고    scopus 로고
    • Salvianolic acid B attenuates brain damage and inflammation after traumatic brain injury in mice
    • Chen T, Liu W, Chao X, Zhang L, Qu Y, et al. (2011) Salvianolic acid B attenuates brain damage and inflammation after traumatic brain injury in mice. Brain Res Bull 84: 163-168.
    • (2011) Brain Res Bull , vol.84 , pp. 163-168
    • Chen, T.1    Liu, W.2    Chao, X.3    Zhang, L.4    Qu, Y.5
  • 18
    • 71049180223 scopus 로고    scopus 로고
    • Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats
    • Tsai MK, Lin YL, Huang YT (2010) Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats. Toxicol Appl Pharmacol 242: 155-164.
    • (2010) Toxicol Appl Pharmacol , vol.242 , pp. 155-164
    • Tsai, M.K.1    Lin, Y.L.2    Huang, Y.T.3
  • 19
    • 39049123781 scopus 로고    scopus 로고
    • Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents 6-hydroxydopamine induced apoptosis in SH-SY5Y cells
    • Tian LL, Wang XJ, Sun YN, Li CR, Xing YL, et al. (2008) Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents 6-hydroxydopamine induced apoptosis in SH-SY5Y cells. Int J Biochem Cell Biol 40: 409-422.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 409-422
    • Tian, L.L.1    Wang, X.J.2    Sun, Y.N.3    Li, C.R.4    Xing, Y.L.5
  • 20
    • 77956132036 scopus 로고    scopus 로고
    • Salvianolic acid B protects SH-SY5Y neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptosis
    • Zeng G, Tang T, Wu HJ, You WH, Luo JK, et al. (2010) Salvianolic acid B protects SH-SY5Y neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptosis. Biol Pharm Bull 33: 1337-1342.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1337-1342
    • Zeng, G.1    Tang, T.2    Wu, H.J.3    You, W.H.4    Luo, J.K.5
  • 21
    • 0036316772 scopus 로고    scopus 로고
    • Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease
    • DOI 10.1046/j.1471-4159.2002.00928.x
    • Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, et al. (2002) Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. J Neurochem 81: 1285-1297. (Pubitemid 34809262)
    • (2002) Journal of Neurochemistry , vol.81 , Issue.6 , pp. 1285-1297
    • Gao, H.-M.1    Jiang, J.2    Wilson, B.3    Zhang, W.4    Hong, J.-S.5    Liu, B.6
  • 22
    • 84884737609 scopus 로고    scopus 로고
    • Homer1 knockdown protects dopamine neurons through regulating calcium homeostasis in an in vitro model of Parkinson's disease
    • Chen T, Yang YF, Luo P, Liu W, Dai SH, et al. (2013) Homer1 knockdown protects dopamine neurons through regulating calcium homeostasis in an in vitro model of Parkinson's disease. Cell Signal 25: 2863-2870.
    • (2013) Cell Signal , vol.25 , pp. 2863-2870
    • Chen, T.1    Yang, Y.F.2    Luo, P.3    Liu, W.4    Dai, S.H.5
  • 23
    • 0036470165 scopus 로고    scopus 로고
    • Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons
    • Gao HM, Hong JS, Zhang W, Liu B (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci 22: 782-790. (Pubitemid 34141759)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 782-790
    • Gao, H.-M.1    Hong, J.-S.2    Zhang, W.3    Liu, B.4
  • 24
    • 77549087710 scopus 로고    scopus 로고
    • Preventative effects of 1,3-dimethyl- and 1,3-dimethyl-N-propargyl-1,2,3, 4-tetrahydroisoquinoline on MPTP-induced Parkinson's disease-like symptoms in mice
    • Katagiri N, Chida S, Abe K, Nojima H, Kitabatake M, et al. (2010) Preventative effects of 1,3-dimethyl- and 1,3-dimethyl-N-propargyl-1,2,3,4- tetrahydroisoquinoline on MPTP-induced Parkinson's disease-like symptoms in mice. Brain Res 1321: 133-142.
    • (2010) Brain Res , vol.1321 , pp. 133-142
    • Katagiri, N.1    Chida, S.2    Abe, K.3    Nojima, H.4    Kitabatake, M.5
  • 25
    • 80053118896 scopus 로고    scopus 로고
    • S-Allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice
    • Rojas P, Serrano-Garcia N, Medina-Campos ON, Pedraza-Chaverri J, Maldonado PD, et al. (2011) S-Allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice. J Nutr Biochem 22: 937-944.
    • (2011) J Nutr Biochem , vol.22 , pp. 937-944
    • Rojas, P.1    Serrano-Garcia, N.2    Medina-Campos, O.N.3    Pedraza-Chaverri, J.4    Maldonado, P.D.5
  • 27
    • 82055208103 scopus 로고    scopus 로고
    • L-Dopa prodrugs: An overview of trends for improving Parkinson's disease treatment
    • Di Stefano A, Sozio P, Cerasa LS, Iannitelli A (2011) L-Dopa prodrugs: an overview of trends for improving Parkinson's disease treatment. Curr Pharm Des 17: 3482-3493.
    • (2011) Curr Pharm des , vol.17 , pp. 3482-3493
    • Di Stefano, A.1    Sozio, P.2    Cerasa, L.S.3    Iannitelli, A.4
  • 28
    • 79960244516 scopus 로고    scopus 로고
    • L-DOPA: A scapegoat for accelerated neurodegeneration in Parkinson's disease?
    • Lipski J, Nistico R, Berretta N, Guatteo E, Bernardi G, et al. (2011) L-DOPA: a scapegoat for accelerated neurodegeneration in Parkinson's disease? Prog Neurobiol 94: 389-407.
    • (2011) Prog Neurobiol , vol.94 , pp. 389-407
    • Lipski, J.1    Nistico, R.2    Berretta, N.3    Guatteo, E.4    Bernardi, G.5
  • 29
    • 0027486512 scopus 로고
    • Experimental Parkinson's disease in monkeys. Effect of ergot alkaloid derivative on lipid peroxidation in different brain areas
    • DOI 10.1007/BF00966691
    • Marzatico F, Cafe C, Taborelli M, Benzi G (1993) Experimental Parkinson's disease in monkeys. Effect of ergot alkaloid derivative on lipid peroxidation in different brain areas. Neurochem Res 18: 1101-1106. (Pubitemid 23309276)
    • (1993) Neurochemical Research , vol.18 , Issue.10 , pp. 1101-1106
    • Marzatico, F.1    Cafe, C.2    Taborelli, M.3    Benzi, G.4
  • 30
    • 79551664192 scopus 로고    scopus 로고
    • The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson's disease
    • Campos HC, da Rocha MD, Viegas FP, Nicastro PC, Fossaluzza PC, et al. (2011) The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson's disease. CNS Neurol Disord Drug Targets 10: 239-250.
    • (2011) CNS Neurol Disord Drug Targets , vol.10 , pp. 239-250
    • Campos, H.C.1    Da Rocha, M.D.2    Viegas, F.P.3    Nicastro, P.C.4    Fossaluzza, P.C.5
  • 31
    • 20944441667 scopus 로고    scopus 로고
    • Natural products and derivatives affecting neurotransmission relevant to Alzheimer's and Parkinson's disease
    • DOI 10.1159/000085382
    • Houghton PJ, Howes MJ (2005) Natural products and derivatives affecting neurotransmission relevant to Alzheimer's and Parkinson's disease. Neurosignals 14: 6-22. (Pubitemid 40868980)
    • (2005) NeuroSignals , vol.14 , Issue.1-2 , pp. 6-22
    • Houghton, P.J.1    Howes, M.-J.2
  • 32
    • 33745447134 scopus 로고    scopus 로고
    • The pharmacological effects of Salvia species on the central nervous system
    • DOI 10.1002/ptr.1898
    • Imanshahidi M, Hosseinzadeh H (2006) The pharmacological effects of Salvia species on the central nervous system. Phytother Res 20: 427-437. (Pubitemid 43953393)
    • (2006) Phytotherapy Research , vol.20 , Issue.6 , pp. 427-437
    • Imanshahidi, M.1    Hosseinzadeh, H.2
  • 33
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
    • DOI 10.1177/0091270005282630
    • Zhou L, Zuo Z, Chow MS (2005) Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 45: 1345-1359. (Pubitemid 41643896)
    • (2005) Journal of Clinical Pharmacology , vol.45 , Issue.12 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.S.3
  • 34
    • 79955776388 scopus 로고    scopus 로고
    • Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection
    • Ho JH, Hong CY (2011) Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection. J Biomed Sci 18: 30.
    • (2011) J Biomed Sci , vol.18 , pp. 30
    • Ho, J.H.1    Hong, C.Y.2
  • 35
    • 0023911192 scopus 로고
    • MPTP toxicity: Implications for research in Parkinson's disease
    • Kopin IJ, Markey SP (1988) MPTP toxicity: implications for research in Parkinson's disease. Annu Rev Neurosci 11: 81-96. (Pubitemid 18081034)
    • (1988) Annual Review of Neuroscience , vol.11 , pp. 81-96
    • Kopin, I.J.1    Markey, S.P.2
  • 37
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton KF, Singer TP (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J Neurochem 61: 1191-1206. (Pubitemid 23285075)
    • (1993) Journal of Neurochemistry , vol.61 , Issue.4 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 39
    • 0037394420 scopus 로고    scopus 로고
    • +)-induced apoptosis and mitochondrial oxidant generation: Role of transferrin-receptor-dependent iron and hydrogen peroxide
    • DOI 10.1042/BJ20021525
    • Kalivendi SV, Kotamraju S, Cunningham S, Shang T, Hillard CJ, et al. (2003) 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. Biochem J 371: 151-164. (Pubitemid 36458089)
    • (2003) Biochemical Journal , vol.371 , Issue.1 , pp. 151-164
    • Kalivendi, S.V.1    Kotamraju, S.2    Cunningham, S.3    Shang, T.4    Hillard, C.J.5    Kalyanaraman, B.6
  • 40
    • 79951499176 scopus 로고    scopus 로고
    • Glia: Initiators and progressors of pathology in Parkinson's disease
    • Halliday GM, Stevens CH (2011) Glia: initiators and progressors of pathology in Parkinson's disease. Mov Disord 26: 6-17.
    • (2011) Mov Disord , vol.26 , pp. 6-17
    • Halliday, G.M.1    Stevens, C.H.2
  • 41
    • 70349958031 scopus 로고    scopus 로고
    • The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease
    • Ciesielska A, Joniec I, Kurkowska-Jastrzebska I, Cudna A, Przybylkowski A, et al. (2009) The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease. Inflamm Res 58: 747-753.
    • (2009) Inflamm Res , vol.58 , pp. 747-753
    • Ciesielska, A.1    Joniec, I.2    Kurkowska-Jastrzebska, I.3    Cudna, A.4    Przybylkowski, A.5
  • 42
    • 84871529499 scopus 로고    scopus 로고
    • In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease
    • Iannaccone S, Cerami C, Alessio M, Garibotto V, Panzacchi A, et al. (2013) In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease. Parkinsonism Relat Disord 19: 47-52.
    • (2013) Parkinsonism Relat Disord , vol.19 , pp. 47-52
    • Iannaccone, S.1    Cerami, C.2    Alessio, M.3    Garibotto, V.4    Panzacchi, A.5
  • 43
    • 0037366093 scopus 로고    scopus 로고
    • Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: Implications for Parkinson's disease
    • Wilms H, Rosenstiel P, Sievers J, Deuschl G, Zecca L, et al. (2003) Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J 17: 500-502.
    • (2003) FASEB J , vol.17 , pp. 500-502
    • Wilms, H.1    Rosenstiel, P.2    Sievers, J.3    Deuschl, G.4    Zecca, L.5
  • 44
    • 25144468525 scopus 로고    scopus 로고
    • To be or not to be (inflamed) - Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
    • DOI 10.1016/j.tips.2005.08.007, PII S0165614705002051
    • Marchetti B, Abbracchio MP (2005) To be or not to be (inflamed)-is that the question in anti-inflammatory drug therapy of neurodegenerative disorders? Trends Pharmacol Sci 26: 517-525. (Pubitemid 41338562)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.10 , pp. 517-525
    • Marchetti, B.1    Abbracchio, M.P.2
  • 45
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit WJ (2002) Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40: 133-139.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 46
    • 4444328360 scopus 로고    scopus 로고
    • Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra
    • DOI 10.1016/j.brainres.2004.07.012, PII S0006899304011266
    • Stanic D, Tripanichkul W, Drago J, Finkelstein DI, Horne MK (2004) Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra. Brain Res 1023: 83-91. (Pubitemid 39195337)
    • (2004) Brain Research , vol.1023 , Issue.1 , pp. 83-91
    • Stanic, D.1    Tripanichkul, W.2    Drago, J.3    Finkelstein, D.I.4    Horne, M.K.5
  • 47
    • 0032102358 scopus 로고    scopus 로고
    • Microglia-specific localisation of a novel calcium binding protein, Iba1
    • DOI 10.1016/S0169-328X(98)00040-0, PII S0169328X98000400
    • Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, et al. (1998) Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Res Mol Brain Res 57: 1-9. (Pubitemid 28279554)
    • (1998) Molecular Brain Research , vol.57 , Issue.1 , pp. 1-9
    • Ito, D.1    Imai, Y.2    Ohsawa, K.3    Nakajima, K.4    Fukuuchi, Y.5    Kohsaka, S.6
  • 49
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson's disease: Role for cytokines
    • DOI 10.2174/1381612053381620
    • Nagatsu T, Sawada M (2005) Inflammatory process in Parkinson's disease: role for cytokines. Curr Pharm Des 11: 999-1016. (Pubitemid 40331301)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.8 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 50
    • 0037007647 scopus 로고    scopus 로고
    • Astroglia induce neurogenesis from adult neural stem cells
    • DOI 10.1038/417039a
    • Song H, Stevens CF, Gage FH (2002) Astroglia induce neurogenesis from adult neural stem cells. Nature 417: 39-44. (Pubitemid 34498810)
    • (2002) Nature , vol.417 , Issue.6884 , pp. 39-44
    • Song, H.1    Stevens, C.F.2    Gage, F.H.3
  • 51
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • DOI 10.1016/S0092-8674(00)80783-7
    • Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97: 703-716. (Pubitemid 29278045)
    • (1999) Cell , vol.97 , Issue.6 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 52
    • 21344434089 scopus 로고    scopus 로고
    • Astrocytes as targets for neuroprotective drugs
    • Darlington CL (2005) Astrocytes as targets for neuroprotective drugs. Curr Opin Investig Drugs 6: 700-703.
    • (2005) Curr Opin Investig Drugs , vol.6 , pp. 700-703
    • Darlington, C.L.1
  • 53
    • 7244253081 scopus 로고    scopus 로고
    • Nrf2-Keap1 defines a physiologically important stress response mechanism
    • DOI 10.1016/j.molmed.2004.09.003, PII S1471491404002357
    • Motohashi H, Yamamoto M (2004) Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol Med 10: 549-557. (Pubitemid 39433824)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.11 , pp. 549-557
    • Motohashi, H.1    Yamamoto, M.2
  • 54
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, et al. (1999) Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13: 76-86. (Pubitemid 29045117)
    • (1999) Genes and Development , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 55
    • 58849090439 scopus 로고    scopus 로고
    • Transcribe to survive: Transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease
    • Clark J, Simon DK (2009) Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxid Redox Signal 11: 509-528.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 509-528
    • Clark, J.1    Simon, D.K.2
  • 56
    • 0035963293 scopus 로고    scopus 로고
    • Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
    • DOI 10.1038/sj.onc.1204506
    • Dhakshinamoorthy S, Jaiswal AK (2001) Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: quinone oxidoreductase1 gene. Oncogene 20: 3906-3917. (Pubitemid 32646201)
    • (2001) Oncogene , vol.20 , Issue.29 , pp. 3906-3917
    • Dhakshinamoorthy, S.1    Jaiswal, A.K.2
  • 58
    • 79955057180 scopus 로고    scopus 로고
    • The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease
    • Tufekci KU, Civi Bayin E, Genc S, Genc K (2011) The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease. Parkinsons Dis 2011: 314082.
    • (2011) Parkinsons Dis , vol.2011 , pp. 314082
    • Tufekci, K.U.1    Civi Bayin, E.2    Genc, S.3    Genc, K.4
  • 59
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2- mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
    • Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, et al. (2009) Nrf2- mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A 106: 2933-2938.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5
  • 60
    • 32544455798 scopus 로고    scopus 로고
    • Astrocytes induce hemeoxygenase-1 expression in microglia: A feasible mechanism for preventing excessive brain inflammation
    • DOI 10.1523/JNEUROSCI.3696-05.2006
    • Min KJ, Yang MS, Kim SU, Jou I, Joe EH (2006) Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation. J Neurosci 26: 1880-1887. (Pubitemid 43237001)
    • (2006) Journal of Neuroscience , vol.26 , Issue.6 , pp. 1880-1887
    • Min, K.-J.1    Yang, M.-S.2    Kim, S.-U.3    Jou, I.4    Joe, E.-H.5
  • 61
    • 84890109914 scopus 로고    scopus 로고
    • Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases
    • Kumar H, Kim IS, More SV, Kim BW, Choi DK (2014) Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases. Nat Prod Rep 31: 109-139.
    • (2014) Nat Prod Rep , vol.31 , pp. 109-139
    • Kumar, H.1    Kim, I.S.2    More, S.V.3    Kim, B.W.4    Choi, D.K.5
  • 62
    • 84894233729 scopus 로고    scopus 로고
    • Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling
    • Zhang H, Liu YY, Jiang Q, Li KR, Zhao YX, et al. (2014) Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling. Free Radic Biol Med 69: 219-228.
    • (2014) Free Radic Biol Med , vol.69 , pp. 219-228
    • Zhang, H.1    Liu, Y.Y.2    Jiang, Q.3    Li, K.R.4    Zhao, Y.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.