메뉴 건너뛰기




Volumn 3, Issue 1, 2013, Pages 13-17

MTOR inhibition alleviates L-DOPA-induced dyskinesia in parkinsonian rats

Author keywords

dyskinesia; mTOR inhibition; Parkinson's disease

Indexed keywords

LEVODOPA; MAMMALIAN TARGET OF RAPAMYCIN; TEMSIROLIMUS;

EID: 84880243271     PISSN: 18777171     EISSN: 1877718X     Source Type: Journal    
DOI: 10.3233/JPD-120155     Document Type: Article
Times cited : (43)

References (14)
  • 1
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodoparelated dyskinesias and motor fluctuations as estimated from the cumulative literature
    • Ahlskog JE, & Muenter MD (2001) Frequency of levodoparelated dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord, 16, 448-458.
    • (2001) Mov Disord , vol.16 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 2
    • 0037096360 scopus 로고    scopus 로고
    • D1 dopamine receptor supersensitivity in the dopaminedepleted striatum results from a switch in the regulation of ERK1/2/MAP kinase
    • Gerfen CR, Miyachi S, Paletzki R, & Brown P (2002) D1 dopamine receptor supersensitivity in the dopaminedepleted striatum results from a switch in the regulation of ERK1/2/MAP kinase. J Neurosci, 22, 5042-5054.
    • (2002) J Neurosci , vol.22 , pp. 5042-5054
    • Gerfen, C.R.1    Miyachi, S.2    Paletzki, R.3    Brown, P.4
  • 3
    • 70349572635 scopus 로고    scopus 로고
    • Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia
    • Santini E, Heiman M, Greengard P, Valjent E, & Fisone G (2009) Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia. Sci Signal, 2, ra36.
    • (2009) Sci Signal , vol.2
    • Santini, E.1    Heiman, M.2    Greengard, P.3    Valjent, E.4    Fisone, G.5
  • 4
  • 6
    • 80155142474 scopus 로고    scopus 로고
    • Rapamycin passes the torch: A new generation of mTOR inhibitors
    • Benjamin D, Colombi M, Moroni C, & Hall MN (2011) Rapamycin passes the torch: A new generation of mTOR inhibitors. Nat Rev Drug Discov, 10, 868-880.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 868-880
    • Benjamin, D.1    Colombi, M.2    Moroni, C.3    Hall, M.N.4
  • 7
    • 77956860980 scopus 로고    scopus 로고
    • MTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter
    • Santini E, Valjent E, & Fisone G (2010) mTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter. Cell Cycle, 9, 2713-2718.
    • (2010) Cell Cycle , vol.9 , pp. 2713-2718
    • Santini, E.1    Valjent, E.2    Fisone, G.3
  • 8
    • 84859889965 scopus 로고    scopus 로고
    • Comparison of the behavioural and histological characteristics of the 6-OHDAand alpha-synuclein rat models of Parkinson's disease
    • Decressac M, Mattsson B,&Bj̈orklundA(2012) Comparison of the behavioural and histological characteristics of the 6-OHDAand alpha-synuclein rat models of Parkinson's disease. Exp Neurol, 235, 306-315.
    • (2012) Exp Neurol , vol.235 , pp. 306-315
    • Decressac, M.1    Mattsson, B.2    Bj̈orklund, A.3
  • 10
    • 0033932460 scopus 로고    scopus 로고
    • Embryonic ventral mesencephalic grafts improve levodopainduced dyskinesia in a rat model of Parkinson's disease
    • Lee CS, Cenci MA, Schulzer M, & Bj̈orklund A (2000) Embryonic ventral mesencephalic grafts improve levodopainduced dyskinesia in a rat model of Parkinson's disease. Brain, 123(Pt 7), 1365-1379.
    • (2000) Brain , vol.123 , Issue.PART 7 , pp. 1365-1379
    • Lee, C.S.1    Cenci, M.A.2    Schulzer, M.3    Bj̈orklund, A.4
  • 11
    • 0036459952 scopus 로고    scopus 로고
    • Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
    • Lundblad M, Andersson M,Winkler C, Kirik D,Wierup N,& Cenci MA (2002) Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. Eur J Neurosci, 15, 120-132.
    • (2002) Eur J Neurosci , vol.15 , pp. 120-132
    • Lundblad, M.1    Andersson, M.2    Winkler, C.3    Kirik, D.4    Wierup, N.5    Cenci, M.A.6
  • 14
    • 77954630538 scopus 로고    scopus 로고
    • Recent advances in the development of selective, ATP-competitive inhibitors of mTOR
    • Richard DJ, Verheijen JC, & Zask A (2010) Recent advances in the development of selective, ATP-competitive inhibitors of mTOR. Curr Opin Drug Discov Devel, 13, 428-440.
    • (2010) Curr Opin Drug Discov Devel , vol.13 , pp. 428-440
    • Richard, D.J.1    Verheijen, J.C.2    Zask, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.