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Volumn 31, Issue 4, 2016, Pages 258-269

Aromatase: Contributions to physiology and disease in women and men

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; AROMATASE INHIBITOR; ESTROGEN;

EID: 84983805437     PISSN: 15489213     EISSN: 15489221     Source Type: Journal    
DOI: 10.1152/physiol.00054.2015     Document Type: Review
Times cited : (137)

References (169)
  • 1
    • 84938261759 scopus 로고    scopus 로고
    • Reduction in endometrioma size with three months of aromatase inhibition and progestin add-back
    • Agarwal SK, Foster WG. Reduction in endometrioma size with three months of aromatase inhibition and progestin add-back. Biomed Res (Tokyo) 2015: 878517, 2015.
    • (2015) Biomed Res (Tokyo) , vol.2015 , pp. 878517
    • Agarwal, S.K.1    Foster, W.G.2
  • 2
    • 0027315887 scopus 로고
    • Mechanistic studies on aromatase and related C-C bond cleaving P-450 enzymes
    • Akhtar M, Njar VC, Wright JN. Mechanistic studies on aromatase and related C-C bond cleaving P-450 enzymes. Steroid Biochem Mol Biol 44: 375-387, 1993.
    • (1993) Steroid Biochem Mol Biol , vol.44 , pp. 375-387
    • Akhtar, M.1    Njar, V.C.2    Wright, J.N.3
  • 5
    • 80052663463 scopus 로고    scopus 로고
    • Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: A systematic review and meta-analysis
    • Amir E, Seruga B, Niraula S, Carlsson L, Ocaña A. Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: A systematic review and meta-analysis. J Natl Cancer Inst 103: 1299-1309, 2011.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1299-1309
    • Amir, E.1    Seruga, B.2    Niraula, S.3    Carlsson, L.4    Ocaña, A.5
  • 8
    • 84875530244 scopus 로고    scopus 로고
    • Meta-analysis of breast cancer outcome and toxicity in adjuvant trials of aromatase inhibitors in postmenopausal women
    • Aydiner A. Meta-analysis of breast cancer outcome and toxicity in adjuvant trials of aromatase inhibitors in postmenopausal women. Breast 22: 121-129, 2013.
    • (2013) Breast , vol.22 , pp. 121-129
    • Aydiner, A.1
  • 9
    • 0031120062 scopus 로고    scopus 로고
    • Steroid control and sexual differentiation of brain aromatase
    • Balthazart J. Steroid control and sexual differentiation of brain aromatase. J Steroid Biochem 61: 323-339, 1997.
    • (1997) J Steroid Biochem , vol.61 , pp. 323-339
    • Balthazart, J.1
  • 10
    • 0032102369 scopus 로고    scopus 로고
    • New insights into the regulation and function of brain estrogen synthase (aromatase)
    • Balthazart GF, Ball J. New insights into the regulation and function of brain estrogen synthase (aromatase). Trends Neurosci 21: 243-248, 1998.
    • (1998) Trends Neurosci , vol.21 , pp. 243-248
    • Balthazart, G.F.1    Ball, J.2
  • 14
    • 0017147434 scopus 로고
    • Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats
    • Beyer C, Moralí G, Naftolin F, Larsson K, Pérez-palacios G. Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats. Horm Behav 7: 353-363, 1976.
    • (1976) Horm Behav , vol.7 , pp. 353-363
    • Beyer, C.1    Moralí, G.2    Naftolin, F.3    Larsson, K.4    Pérez-Palacios, G.5
  • 15
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Bjornstrom M, Sjoberg L. Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 19: 833-842, 2005.
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Bjornstrom, M.1    Sjoberg, L.2
  • 16
    • 84923138537 scopus 로고    scopus 로고
    • Extended adjuvant endocrine therapy in hormonereceptor positive early breast cancer: Current and future evidence
    • Blok EJ, Derks MG, van der Hoeven JJ, van de Velde CJ, Kroep JR. Extended adjuvant endocrine therapy in hormonereceptor positive early breast cancer: Current and future evidence. Cancer Treat Rev 41: 271-276, 2015.
    • (2015) Cancer Treat Rev , vol.41 , pp. 271-276
    • Blok, E.J.1    Derks, M.G.2    van der Hoeven, J.J.3    van de Velde, C.J.4    Kroep, J.R.5
  • 18
    • 13344260687 scopus 로고    scopus 로고
    • Molecular genetic analysis of clear cell adenocarcinomas of the vagina and cervix associated and unassociated with diethylstilbestrol exposure in utero
    • Boyd J, Takahashi H, Waggoner SE, Jones LA, Hajek RA, Wharton JT, Liu FS, Fujino T, Barrett JC, McLachlan JA. Molecular genetic analysis of clear cell adenocarcinomas of the vagina and cervix associated and unassociated with diethylstilbestrol exposure in utero. Cancer 77: 507-513, 1996.
    • (1996) Cancer , vol.77 , pp. 507-513
    • Boyd, J.1    Takahashi, H.2    Waggoner, S.E.3    Jones, L.A.4    Hajek, R.A.5    Wharton, J.T.6    Liu, F.S.7    Fujino, T.8    Barrett, J.C.9    McLachlan, J.A.10
  • 19
    • 24944546451 scopus 로고    scopus 로고
    • Aromatase inhibitors increase the sensitivity of human tumor cells to monocytemediated, antibody-dependent cellular cytotoxicity
    • Braun DP, Crist KA, Shaheen F, Staren ED, Andrews S, Parker J. Aromatase inhibitors increase the sensitivity of human tumor cells to monocytemediated, antibody-dependent cellular cytotoxicity. Am J Surg 190: 570-571, 2005.
    • (2005) Am J Surg , vol.190 , pp. 570-571
    • Braun, D.P.1    Crist, K.A.2    Shaheen, F.3    Staren, E.D.4    Andrews, S.5    Parker, J.6
  • 20
    • 57849152888 scopus 로고    scopus 로고
    • The Coffey Lecture: Steroidogenic enzyme inhibitors and hormone dependent cancer
    • Brodie A, Njar V, Macedo LF, Vasaitis TS, Sabnis G. The Coffey Lecture: Steroidogenic enzyme inhibitors and hormone dependent cancer. Urol Oncol 27: 53-63, 2009.
    • (2009) Urol Oncol , vol.27 , pp. 53-63
    • Brodie, A.1    Njar, V.2    Macedo, L.F.3    Vasaitis, T.S.4    Sabnis, G.5
  • 22
    • 84893441077 scopus 로고    scopus 로고
    • Aromatase and estrogen receptor alpha deficiency
    • Bulun SE. Aromatase and estrogen receptor alpha deficiency. Fertil Steril 101: 323-329, 2014.
    • (2014) Fertil Steril , vol.101 , pp. 323-329
    • Bulun, S.E.1
  • 23
  • 24
    • 0017223888 scopus 로고
    • Cytochrome P-450 and the aromatization of 16alpha-hydroxytestosterone and androstenedione by human placental microsomes
    • Canick JA, Ryan KJ. Cytochrome P-450 and the aromatization of 16alpha-hydroxytestosterone and androstenedione by human placental microsomes. Mol Cell Endocrinol 6: 105-115, 1976.
    • (1976) Mol Cell Endocrinol , vol.6 , pp. 105-115
    • Canick, J.A.1    Ryan, K.J.2
  • 25
    • 0032695247 scopus 로고    scopus 로고
    • Role of oestrogen in male sexual behavior: Insights from the natural model of aromatase deficiency
    • Carani C, Rochira V, Faustini-Fustini M, Balestrieri A, Granata AR. Role of oestrogen in male sexual behavior: Insights from the natural model of aromatase deficiency. Clin Endocrinol 51: 517-524, 1999.
    • (1999) Clin Endocrinol , vol.51 , pp. 517-524
    • Carani, C.1    Rochira, V.2    Faustini-Fustini, M.3    Balestrieri, A.4    Granata, A.R.5
  • 27
    • 0036798936 scopus 로고    scopus 로고
    • Estrogen modulation of endothelial nitric oxide synthase
    • Chambliss KL, Shaul PW. Estrogen modulation of endothelial nitric oxide synthase. Endocrinology 23: 665-686, 2002.
    • (2002) Endocrinology , vol.23 , pp. 665-686
    • Chambliss, K.L.1    Shaul, P.W.2
  • 29
    • 84938055350 scopus 로고    scopus 로고
    • Menopausal hormone therapy influence on breast cancer outcomes in the Women’s Health Initiative
    • Chlebowski RT, Aragaki AK, Anderson GL. Menopausal hormone therapy influence on breast cancer outcomes in the Women’s Health Initiative. J Natl Compr Canc Netw 13: 917-924, 2015.
    • (2015) J Natl Compr Canc Netw , vol.13 , pp. 917-924
    • Chlebowski, R.T.1    Aragaki, A.K.2    Anderson, G.L.3
  • 30
    • 0028153564 scopus 로고
    • Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNFinduced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1
    • Cid MC, Kleinman HK, Grant DS, Schnaper HW, Fauci AS, Hoffman GS. Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNFinduced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1. J Clin Invest 93: 17-25, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 17-25
    • Cid, M.C.1    Kleinman, H.K.2    Grant, D.S.3    Schnaper, H.W.4    Fauci, A.S.5    Hoffman, G.S.6
  • 31
    • 84874779493 scopus 로고    scopus 로고
    • Timing hypothesis for postmenopausal hormone therapy: Its origin, current status, and future
    • Clarkson TB, Meléndez GC, Appt SE. Timing hypothesis for postmenopausal hormone therapy:its origin, current status, and future. Menopause 20: 342-353, 2013.
    • (2013) Menopause , vol.20 , pp. 342-353
    • Clarkson, T.B.1    Meléndez, G.C.2    Appt, S.E.3
  • 32
    • 37349036467 scopus 로고    scopus 로고
    • Obesity in men: The hypogonadolestrogen receptor relationship and its effect on glucose homeostasis
    • Cohen PG. Obesity in men: The hypogonadolestrogen receptor relationship and its effect on glucose homeostasis. Med Hypotheses 70: 358-360, 2008.
    • (2008) Med Hypotheses , vol.70 , pp. 358-360
    • Cohen, P.G.1
  • 33
    • 0028298216 scopus 로고
    • A syndrome of female pseudohermaphrodism, hypergonadotropic hypogonadism and multicystic ovaries associated with missense mutations in the gene encoding aromatase (P450arom)
    • Conte FA, Grumbach MM, Ito Y, Fisher CR, Simpson ER. A syndrome of female pseudohermaphrodism, hypergonadotropic hypogonadism and multicystic ovaries associated with missense mutations in the gene encoding aromatase (P450arom). J Clin Endocrinol Metab 78: 1287-1292, 1994.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1287-1292
    • Conte, F.A.1    Grumbach, M.M.2    Ito, Y.3    Fisher, C.R.4    Simpson, E.R.5
  • 34
    • 0013806133 scopus 로고
    • The effect of progesterone on the human uterus
    • Csapo AI, Pinto-Dantas CA. The effect of progesterone on the human uterus. Proc Natl Acad Sci USA 54: 1069-1076, 1965.
    • (1965) Proc Natl Acad Sci USA , vol.54 , pp. 1069-1076
    • Csapo, A.I.1    Pinto-Dantas, C.A.2
  • 35
    • 84855416617 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) inhibition of monocyte binding by vascular endothelium is associated with sialylation of neural cell adhesion molecule
    • Curatola AM, Huang K, Naftolin F. Dehydroepiandrosterone (DHEA) inhibition of monocyte binding by vascular endothelium is associated with sialylation of neural cell adhesion molecule. Reprod Sci 19: 86-91, 2012.
    • (2012) Reprod Sci , vol.19 , pp. 86-91
    • Curatola, A.M.1    Huang, K.2    Naftolin, F.3
  • 36
    • 0033326235 scopus 로고    scopus 로고
    • Aromatase deficiency caused by a novel P450arom gene mutation: Impact of absent estrogen production on serum gonadotropin concentration in a boy
    • Deladoey J, Fluck C, Bex M, Yoshimura N, Harada N, Mullis PE. Aromatase deficiency caused by a novel P450arom gene mutation: Impact of absent estrogen production on serum gonadotropin concentration in a boy. J Clin Endocrinol Metab 84: 4050-4054, 1999.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4050-4054
    • Deladoey, J.1    Fluck, C.2    Bex, M.3    Yoshimura, N.4    Harada, N.5    Mullis, P.E.6
  • 37
    • 84888329808 scopus 로고    scopus 로고
    • Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS
    • Dey P1, Barros RP, Warner M, Ström A, Gustafsson JÅ. Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS. J Mol Endocrinol 51: 61-74, 2013.
    • (2013) J Mol Endocrinol , vol.51 , pp. 61-74
    • Dey, P.1    Barros, R.P.2    Warner, M.3    Ström, A.4    Jå, G.5
  • 39
    • 0032999125 scopus 로고    scopus 로고
    • Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects
    • Diano S, Horvath TL, Mor G, Register T, Adams M, Harada N, Naftolin F. Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects. Menopause 6: 21-28, 1999.
    • (1999) Menopause , vol.6 , pp. 21-28
    • Diano, S.1    Horvath, T.L.2    Mor, G.3    Register, T.4    Adams, M.5    Harada, N.6    Naftolin, F.7
  • 40
    • 0001569157 scopus 로고
    • Follicle-stimulating hormone stimulates estradiol-17beta synthesis in cultured sertoli cells
    • Dorrington JH, Armstrong DT. Follicle-stimulating hormone stimulates estradiol-17beta synthesis in cultured sertoli cells. Proc Natl Acad Sci USA 72: 2677-2681, 1975.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 2677-2681
    • Dorrington, J.H.1    Armstrong, D.T.2
  • 41
    • 33646708559 scopus 로고    scopus 로고
    • The role of steroids in follicular growth
    • Drummond AE. The role of steroids in follicular growth. Reprod Biol Endocrinol 4: 450, 2006.
    • (2006) Reprod Biol Endocrinol , vol.4 , pp. 450
    • Drummond, A.E.1
  • 42
    • 0013935573 scopus 로고
    • Neutral C19-steroids and steroid sulfates in human pregnancy 2. Dehydroepiandrosterone sulfate, 16alpha-hydroxydehydroepiandrosterone, and 16alpha-hydroxydehydroepiandrosterone sulfate in maternal and fetal blood of pregnancies with anencephalic and normal fetuses
    • Easterling WK, Simmer HH, Dignam WJ, Frankland MV, Naftolin F. Neutral C19-steroids and steroid sulfates in human pregnancy 2. Dehydroepiandrosterone sulfate, 16alpha-hydroxydehydroepiandrosterone, and 16alpha-hydroxydehydroepiandrosterone sulfate in maternal and fetal blood of pregnancies with anencephalic and normal fetuses. Steroids 8: 157-178, 1992.
    • (1992) Steroids , vol.8 , pp. 157-178
    • Easterling, W.K.1    Simmer, H.H.2    Dignam, W.J.3    Frankland, M.V.4    Naftolin, F.5
  • 43
    • 0030042339 scopus 로고    scopus 로고
    • Reduced mortality associated with long-term postmenopausal estrogen therapy
    • Ettinger B, Friedman GD, Bush T, Quesenberry CP. Reduced mortality associated with long-term postmenopausal estrogen therapy. Obstet Gynecol 87: 6-12, 1996.
    • (1996) Obstet Gynecol , vol.87 , pp. 6-12
    • Ettinger, B.1    Friedman, G.D.2    Bush, T.3    Quesenberry, C.P.4
  • 44
    • 0023774895 scopus 로고
    • The effects of estradiol on blood lipids and lipoproteins in postmenopausal women
    • Fahraeus L. The effects of estradiol on blood lipids and lipoproteins in postmenopausal women. Obstet Gynecol 72: 18-22, 1988.
    • (1988) Obstet Gynecol , vol.72 , pp. 18-22
    • Fahraeus, L.1
  • 45
    • 0034521393 scopus 로고    scopus 로고
    • Relative contributions of testosterone and estrogen in regulating bone and resorption and formation in normal elderly men
    • Falahati-Nini A, Riggs BL, Atkinson EJ, O’fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone and resorption and formation in normal elderly men. J Clin Invest 106: 1553-1560, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 1553-1560
    • Falahati-Nini, A.1    Riggs, B.L.2    Atkinson, E.J.3    O’fallon, W.M.4    Eastell, R.5    Khosla, S.6
  • 47
    • 0020324229 scopus 로고
    • Biochemical mechanism of aromatization
    • Fishman J. Biochemical mechanism of aromatization. Cancer Res 42, Suppl 8: 3277-3280, 1982.
    • (1982) Cancer Res , vol.42 , pp. 3277-3280
    • Fishman, J.1
  • 48
    • 84923228849 scopus 로고    scopus 로고
    • Aromatase inhibitors for subfertile women with polycystic ovary syndrome: Summary of a Cochrane review
    • Franik S, Kremer JA, Nelen WL, Farquhar C, Marjoribanks J. Aromatase inhibitors for subfertile women with polycystic ovary syndrome: Summary of a Cochrane review. Fertil Steril 103: 353-355, 2015.
    • (2015) Fertil Steril , vol.103 , pp. 353-355
    • Franik, S.1    Kremer, J.A.2    Nelen, W.L.3    Farquhar, C.4    Marjoribanks, J.5
  • 49
    • 0041341792 scopus 로고    scopus 로고
    • Role of estrogen and androgen in pubertal skeletal physiology
    • Frank GR. Role of estrogen and androgen in pubertal skeletal physiology. Pediatr Blood Cancer 41: 217-221, 2003.
    • (2003) Pediatr Blood Cancer , vol.41 , pp. 217-221
    • Frank, G.R.1
  • 50
    • 36049013008 scopus 로고    scopus 로고
    • Polysialic acid-neural cell adhesion molecule in brain plasticity: From synapses to integration of new neurons
    • Gascon E, Vutskits L, Kiss JZ. Polysialic acid-neural cell adhesion molecule in brain plasticity: From synapses to integration of new neurons. Brain Res Rev 56: 101-118, 2007.
    • (2007) Brain Res Rev , vol.56 , pp. 101-118
    • Gascon, E.1    Vutskits, L.2    Kiss, J.Z.3
  • 51
    • 33845474784 scopus 로고    scopus 로고
    • Developments of low-dose reproductive hormone therapies in China
    • Ge Q, Tan Q, Tseng H, Naftolin F. Developments of low-dose reproductive hormone therapies in China. Gynecol Endocrinol 22: 636-645, 2006.
    • (2006) Gynecol Endocrinol , vol.22 , pp. 636-645
    • Ge, Q.1    Tan, Q.2    Tseng, H.3    Naftolin, F.4
  • 54
    • 53849088227 scopus 로고    scopus 로고
    • Transcriptional control of energy homeostasis by the estrogen-related receptors
    • Giguere V. Transcriptional control of energy homeostasis by the estrogen-related receptors. Endocr Rev 29: 677-696, 2008.
    • (2008) Endocr Rev , vol.29 , pp. 677-696
    • Giguere, V.1
  • 55
    • 0017254914 scopus 로고
    • Ovarian and adrenal steroid production in the postmenopausal woman
    • Greenblatt RB, Colle ML, Mahesh VB. Ovarian and adrenal steroid production in the postmenopausal woman. Obstet Gynecol 47: 383-387, 1976.
    • (1976) Obstet Gynecol , vol.47 , pp. 383-387
    • Greenblatt, R.B.1    Colle, M.L.2    Mahesh, V.B.3
  • 57
    • 84881326362 scopus 로고    scopus 로고
    • Pharmacophore modeling for ADME
    • Guner OF, Bowen JP. Pharmacophore modeling for ADME. Curr Top Med Chem 13: 1327-1342, 2013.
    • (2013) Curr Top Med Chem , vol.13 , pp. 1327-1342
    • Guner, O.F.1    Bowen, J.P.2
  • 58
    • 84899940165 scopus 로고    scopus 로고
    • The Women’s Health Initiative trial and related studies: 10 years later: A clinician’s view
    • Gurney EP, Nachtigall MJ, Nachtigall LE, Naftolin F. The Women’s Health Initiative trial and related studies: 10 years later: A clinician’s view. J Steroid Biochem 42: 4-11, 2014.
    • (2014) J Steroid Biochem , vol.42 , pp. 4-11
    • Gurney, E.P.1    Nachtigall, M.J.2    Nachtigall, L.E.3    Naftolin, F.4
  • 59
    • 0036253315 scopus 로고    scopus 로고
    • Progesterone receptor localization and isoforms in myometrium, decidua, and fetal membranes from rhesus macaques: Evidence for functional progesterone withdrawal at parturition
    • Haluska GJ, Wells TR, Hirst JJ, Brenner RM, Sadowsky DW, Novy MJ. Progesterone receptor localization and isoforms in myometrium, decidua, and fetal membranes from rhesus macaques:evidence for functional progesterone withdrawal at parturition. J Soc Gynecol Investig 9: 125-136, 2002.
    • (2002) J Soc Gynecol Investig , vol.9 , pp. 125-136
    • Haluska, G.J.1    Wells, T.R.2    Hirst, J.J.3    Brenner, R.M.4    Sadowsky, D.W.5    Novy, M.J.6
  • 60
    • 80052538267 scopus 로고    scopus 로고
    • Diverse roles for sex hormonebinding globulin reproduction
    • Hammond GL. Diverse roles for sex hormonebinding globulin reproduction. Biol Reprod 85:431-441, 2011.
    • (2011) Biol Reprod , vol.85 , pp. 431-441
    • Hammond, G.L.1
  • 63
    • 41349094340 scopus 로고    scopus 로고
    • Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial)
    • Hodis HN, St John JA, Xiang M, Cushman M, Lobo RA, Mack WJ. Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial). Am J Cardiol 101: 1131-1133, 2009.
    • (2009) Am J Cardiol , vol.101 , pp. 1131-1133
    • Hodis, H.N.1    St John, J.A.2    Xiang, M.3    Cushman, M.4    Lobo, R.A.5    Mack, W.J.6
  • 65
    • 84923165652 scopus 로고    scopus 로고
    • Molecular mechanisms of tamoxifen-associated endometrial cancer
    • Hu R, Hilakivi-Clarke L, Clarke R. Molecular mechanisms of tamoxifen-associated endometrial cancer. Oncol Lett 9: 1495-1501, 2015.
    • (2015) Oncol Lett , vol.9 , pp. 1495-1501
    • Hu, R.1    Hilakivi-Clarke, L.2    Clarke, R.3
  • 66
    • 0021711226 scopus 로고
    • The myometrium and uterine cervix in normal and preterm labor
    • Huszar G, Naftolin F. The myometrium and uterine cervix in normal and preterm labor. N Engl J Med 311: 571-581, 1984.
    • (1984) N Engl J Med , vol.311 , pp. 571-581
    • Huszar, G.1    Naftolin, F.2
  • 67
  • 68
    • 0033304698 scopus 로고    scopus 로고
    • Regulation of angiogenci growth factors in the female reproductive tract by estrogens and progestins
    • Hyder GM, Stancel SM. Regulation of angiogenci growth factors in the female reproductive tract by estrogens and progestins. Mol Endocrinol 13:806-811, 1999.
    • (1999) Mol Endocrinol , vol.13 , pp. 806-811
    • Hyder, G.M.1    Stancel, S.M.2
  • 69
    • 84883402514 scopus 로고    scopus 로고
    • Postmenopausal women with hormone receptor-positive breast cancer: Balancing benefit and toxicity from aromatase inhibitors
    • Ingle JN. Postmenopausal women with hormone receptor-positive breast cancer: balancing benefit and toxicity from aromatase inhibitors. Breast 22, Suppl 2: S180-S183, 2013.
    • (2013) Breast , vol.22 , pp. S180-S183
    • Ingle, J.N.1
  • 72
    • 0036779856 scopus 로고    scopus 로고
    • Sex hormones and neural mechanisms
    • Keefe DL. Sex hormones and neural mechanisms. Arch Sex Behav 31: 401-403, 2002.
    • (2002) Arch Sex Behav , vol.31 , pp. 401-403
    • Keefe, D.L.1
  • 73
    • 0031756218 scopus 로고    scopus 로고
    • Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen 1
    • Khosla S, Melton LJ, Atkinson EJ, O’fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen 1. J Clin Endocrinol Metab 83: 2266-2274, 1998.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2266-2274
    • Khosla, S.1    Melton, L.J.2    Atkinson, E.J.3    O’fallon, W.M.4    Klee, G.G.5    Riggs, B.L.6
  • 74
    • 0141645490 scopus 로고    scopus 로고
    • Communication in neuronal networks
    • Laughlin TJ, Sejnowski SB. Communication in neuronal networks. Science 301: 1870-1874, 2003.
    • (2003) Science , vol.301 , pp. 1870-1874
    • Laughlin, T.J.1    Sejnowski, S.B.2
  • 76
    • 84908006101 scopus 로고    scopus 로고
    • Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: A prospective non-randomized study
    • Leone Roberti Maggiore U, Scala C, Venturini PL, Ferrero S. Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: A prospective non-randomized study. Eur J Obstet Gynecol Reprod Biol 181: 157-162, 2014.
    • (2014) Eur J Obstet Gynecol Reprod Biol , vol.181 , pp. 157-162
    • Leone Roberti Maggiore, U.1    Scala, C.2    Venturini, P.L.3    Ferrero, S.4
  • 77
    • 74049104166 scopus 로고    scopus 로고
    • Estrogen regulation of apoptosis: How can one hormone stimulate and inhibit?
    • Lewis-Wambi JS, Jordan VC. Estrogen regulation of apoptosis: How can one hormone stimulate and inhibit? Breast Cancer Res 11: 206-218, 2009.
    • (2009) Breast Cancer Res , vol.11 , pp. 206-218
    • Lewis-Wambi, J.S.1    Jordan, V.C.2
  • 78
    • 0035902456 scopus 로고    scopus 로고
    • Current concepts of the pathogenesis of the acute coronary syndroms
    • Libby P. Current concepts of the pathogenesis of the acute coronary syndroms. Circulation 104:365-372, 2001.
    • (2001) Circulation , vol.104 , pp. 365-372
    • Libby, P.1
  • 79
    • 84921961337 scopus 로고    scopus 로고
    • Inflammation and immunity in diseases of the arterial tree: Players and layers
    • Libby P, Hansson GK. Inflammation and immunity in diseases of the arterial tree: Players and layers. Circ Res 116: 307-311, 2015.
    • (2015) Circ Res , vol.116 , pp. 307-311
    • Libby, P.1    Hansson, G.K.2
  • 81
    • 84877706065 scopus 로고    scopus 로고
    • Where are we 10 years after the Women’s Health Initiative?
    • Lobo RA. Where are we 10 years after the Women’s Health Initiative? J Clin Endocrinol Metab 98: 1771-1780, 2013.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1771-1780
    • Lobo, R.A.1
  • 82
    • 0022637802 scopus 로고
    • Androgen and estrogen metabolism: Relationship to obesity
    • Longcope C, Baker R, Johnston CC. Androgen and estrogen metabolism: Relationship to obesity. Metabolism 35: 235-237, 1986.
    • (1986) Metabolism , vol.35 , pp. 235-237
    • Longcope, C.1    Baker, R.2    Johnston, C.C.3
  • 83
    • 0019797807 scopus 로고
    • Sexual differentiation of the central nervous system
    • MacLusky NJ, Naftolin F. Sexual differentiation of the central nervous system. Science 211:1294-1302, 1981.
    • (1981) Science , vol.211 , pp. 1294-1302
    • MacLusky, N.J.1    Naftolin, F.2
  • 86
    • 84878632677 scopus 로고    scopus 로고
    • The role of estrogens in control of energy balance and glucose homeostasis
    • Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev 34: 309-338, 2013.
    • (2013) Endocr Rev , vol.34 , pp. 309-338
    • Mauvais-Jarvis, F.1    Clegg, D.J.2    Hevener, A.L.3
  • 87
    • 0141535178 scopus 로고    scopus 로고
    • Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection
    • McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD. Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. J Neurosci 23: 8701-8705, 2003.
    • (2003) J Neurosci , vol.23 , pp. 8701-8705
    • McCullough, L.D.1    Blizzard, K.2    Simpson, E.R.3    Oz, O.K.4    Hurn, P.D.5
  • 88
    • 0018547573 scopus 로고
    • The production of progesterone, androgens, and estrogens by granulosa cells, thecal tissue, and stromal tissue from human ovaries in vitro
    • McNatty KP, Makris A, Degrazia C, Rapin O, Ryan KJ. The production of progesterone, androgens, and estrogens by granulosa cells, thecal tissue, and stromal tissue from human ovaries in vitro. J Clin Endocrinol Metab 49: 687-699, 1979.
    • (1979) J Clin Endocrinol Metab , vol.49 , pp. 687-699
    • McNatty, K.P.1    Makris, A.2    Degrazia, C.3    Rapin, O.4    Ryan, K.J.5
  • 89
    • 79952515594 scopus 로고    scopus 로고
    • Progesterone receptors in the human pregnancy uterus: Do they hold the key to birth timing?
    • Mesiano M, Wang Y, Norwitz ER. Progesterone receptors in the human pregnancy uterus: Do they hold the key to birth timing? Reprod Sci 18:6-19, 2011.
    • (2011) Reprod Sci , vol.18 , pp. 6-19
    • Mesiano, M.1    Wang, Y.2    Norwitz, E.R.3
  • 90
    • 84963702655 scopus 로고    scopus 로고
    • Longitudinal effects of menopausal hormone treatments on platelet characteristics and cell-derived microvesicles
    • Miller VM, Lahr BD, Bailey KR, Heit JA, Harman SM, Jayachandran M. Longitudinal effects of menopausal hormone treatments on platelet characteristics and cell-derived microvesicles. Platelets 9: 1-11, 2015.
    • (2015) Platelets , vol.9 , pp. 1-11
    • Miller, V.M.1    Lahr, B.D.2    Bailey, K.R.3    Heit, J.A.4    Harman, S.M.5    Jayachandran, M.6
  • 95
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 80: 3689-3698, 1995.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 96
    • 0344980592 scopus 로고    scopus 로고
    • Differential regulation of estrogen receptor alpha and beta mRNAs in the rat uterus during pregnancy and labor: Possible involvement of estrogen receptors in oxytocin receptor regulation
    • Murata T, Narita K, Honda K, Matsukawa S, Higuchi T. Differential regulation of estrogen receptor alpha and beta mRNAs in the rat uterus during pregnancy and labor: Possible involvement of estrogen receptors in oxytocin receptor regulation. Endocrine 50: 579-587, 2003.
    • (2003) Endocrine , vol.50 , pp. 579-587
    • Murata, T.1    Narita, K.2    Honda, K.3    Matsukawa, S.4    Higuchi, T.5
  • 97
    • 0028267115 scopus 로고
    • Brain aromatization of androgens
    • Naftolin F. Brain aromatization of androgens. J Reprod Med 39: 257-261, 1994.
    • (1994) J Reprod Med , vol.39 , pp. 257-261
    • Naftolin, F.1
  • 98
    • 0030030338 scopus 로고    scopus 로고
    • Aromatase immunoreactivity in axon terminals of the vertebrate brain: An immunocytochemical study on qual, rat, monkey and human tissues
    • Naftolin F, Horvath TL, Jakab RL, Leranth C, Harada N, Balthazart J. Aromatase immunoreactivity in axon terminals of the vertebrate brain: An immunocytochemical study on qual, rat, monkey and human tissues. Neuroendocrinology 63:149-155, 1996.
    • (1996) Neuroendocrinology , vol.63 , pp. 149-155
    • Naftolin, F.1    Horvath, T.L.2    Jakab, R.L.3    Leranth, C.4    Harada, N.5    Balthazart, J.6
  • 100
    • 0015579446 scopus 로고
    • Pulsatile patterns of gonadotropins and testosterone in man: The effects of clomiphene, with and without testosterone added
    • Naftolin F, Judd HL, Yen SS. Pulsatile patterns of gonadotropins and testosterone in man: The effects of clomiphene, with and without testosterone added. J Clin Endocrinol Metab 36: 285-288, 1973.
    • (1973) J Clin Endocrinol Metab , vol.36 , pp. 285-288
    • Naftolin, F.1    Judd, H.L.2    Yen, S.S.3
  • 102
    • 0015256896 scopus 로고
    • Aromatization of androstenedione by the anterior hypothalamus of adult male and female rats
    • Naftolin F, Ryan KJ, Petro Z. Aromatization of androstenedione by the anterior hypothalamus of adult male and female rats. Endocrinology 90:295-298, 1971.
    • (1971) Endocrinology , vol.90 , pp. 295-298
    • Naftolin, F.1    Ryan, K.J.2    Petro, Z.3
  • 104
    • 0034858481 scopus 로고    scopus 로고
    • Estrogen production and action
    • Nelson LR, Bulun SE. Estrogen production and action. J Am Acad Dermatol 45: S116-S124, 2001.
    • (2001) J Am Acad Dermatol , vol.45 , pp. S116-S124
    • Nelson, L.R.1    Bulun, S.E.2
  • 105
    • 4544253891 scopus 로고    scopus 로고
    • Mitochondria as therapeutic targets of estrogen action in the central nervous system
    • Nilsen J, Brinton RD. Mitochondria as therapeutic targets of estrogen action in the central nervous system. Curr Drug Targets CNS Neurol Disord 3: 297-313, 2004.
    • (2004) Curr Drug Targets CNS Neurol Disord , vol.3 , pp. 297-313
    • Nilsen, J.1    Brinton, R.D.2
  • 106
    • 0034068441 scopus 로고    scopus 로고
    • Estrogen-regulated developmental neuronal apoptosis is determined by estrogen receptor subtype and the Fas/Fas ligand system
    • Nilsen J, Mor G, Naftolin F. Estrogen-regulated developmental neuronal apoptosis is determined by estrogen receptor subtype and the Fas/Fas ligand system. J Neurobiol 43: 64-78, 2000.
    • (2000) J Neurobiol , vol.43 , pp. 64-78
    • Nilsen, J.1    Mor, G.2    Naftolin, F.3
  • 107
    • 0027314085 scopus 로고
    • Multiple functions of aromatase and the active site structure; aromatase is the placental estrogen 2-hydroxylase
    • Osawa Y, Higashiyama T, Shimizu Y, Yarborough C. Multiple functions of aromatase and the active site structure; aromatase is the placental estrogen 2-hydroxylase. J Steroid Biochem 44: 469-480, 1993.
    • (1993) J Steroid Biochem , vol.44 , pp. 469-480
    • Osawa, Y.1    Higashiyama, T.2    Shimizu, Y.3    Yarborough, C.4
  • 108
    • 0031120071 scopus 로고    scopus 로고
    • Diverse function of aromatase and the N-terminal sequence deleted form
    • Osawa Y, Higashiyama T, Toma Y, Yarborough C. Diverse function of aromatase and the N-terminal sequence deleted form. J Steroid Biochem 61: 117-126, 1997.
    • (1997) J Steroid Biochem , vol.61 , pp. 117-126
    • Osawa, Y.1    Higashiyama, T.2    Toma, Y.3    Yarborough, C.4
  • 109
    • 78650080294 scopus 로고    scopus 로고
    • Estradiol regulates expression of polysialated neural cell adhesion molecule by human vascular endothelial cells
    • Park H, Pagan L, Tan O, Fadiel A, Demir N, Huang K, Mittal K, Naftolin F. Estradiol regulates expression of polysialated neural cell adhesion molecule by human vascular endothelial cells. Reprod Sci 17: 1090-1098, 2010.
    • (2010) Reprod Sci , vol.17 , pp. 1090-1098
    • Park, H.1    Pagan, L.2    Tan, O.3    Fadiel, A.4    Demir, N.5    Huang, K.6    Mittal, K.7    Naftolin, F.8
  • 110
    • 67651100633 scopus 로고    scopus 로고
    • Use of the aromatase inhibitor letrozole to treat male infertility
    • Patry G, Jarvi K, Grober ED, Lo KC. Use of the aromatase inhibitor letrozole to treat male infertility. Fertil Steril 92: E1-e2, 2009.
    • (2009) Fertil Steril , vol.92 , pp. e1-e2
    • Patry, G.1    Jarvi, K.2    Grober, E.D.3    Lo, K.C.4
  • 111
    • 84870380514 scopus 로고    scopus 로고
    • Aromatase inhibitors for the treatment of endometriosis
    • Pavone ME, Bulun SE. Aromatase inhibitors for the treatment of endometriosis. Fertil Steril 98:1370-1379, 2012.
    • (2012) Fertil Steril , vol.98 , pp. 1370-1379
    • Pavone, M.E.1    Bulun, S.E.2
  • 112
    • 70349607263 scopus 로고    scopus 로고
    • Cardiovascular risk in menopausal women and prevalent related co-morbid conditions: Facing the post-Women’s health inititiave era
    • Perez-Lopez FR, Chedraui P, Gilbert JJ, Perez-Roncero G. Cardiovascular risk in menopausal women and prevalent related co-morbid conditions:facing the post-Women’s health inititiave era. Fertil Steril 92: 1171-1186, 2009.
    • (2009) Fertil Steril , vol.92 , pp. 1171-1186
    • Perez-Lopez, F.R.1    Chedraui, P.2    Gilbert, J.J.3    Perez-Roncero, G.4
  • 114
    • 0343221442 scopus 로고
    • Action of estradiol 17-beta upon uterine contractility and the milk-ejecting effect in the pregnant woman
    • Pinto RM, Fisch L, Schwarcz Rl Montuori E. Action of estradiol 17-beta upon uterine contractility and the milk-ejecting effect in the pregnant woman. Am J Obstet Gynecol 90: 99-107, 1964.
    • (1964) Am J Obstet Gynecol , vol.90 , pp. 99-107
    • Pinto, R.M.1    Fisch, L.2    Schwarcz Rl Montuori, E.3
  • 116
    • 0036144667 scopus 로고    scopus 로고
    • Aromatase inhibitors for male infertility
    • Raman Schlegal PN JD. Aromatase inhibitors for male infertility. J Urol 167: 624-629, 2002.
    • (2002) J Urol , vol.167 , pp. 624-629
    • Raman Schlegal, P.N.J.D.1
  • 117
    • 0025990208 scopus 로고
    • Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: Deformylation with olefin formation
    • Roberts ES, Vaz AD, Coon MJ. Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: Deformylation with olefin formation. Proc Natl Acad Sci USA 88:8963-8966, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8963-8966
    • Roberts, E.S.1    Vaz, A.D.2    Coon, M.J.3
  • 119
    • 84905388729 scopus 로고    scopus 로고
    • Estradiol binds to insulin and insulin receptor decreasing insulin binding in vitro
    • Root-Bernstein R, Podufaly A, Dillon PF. Estradiol binds to insulin and insulin receptor decreasing insulin binding in vitro. Front Endocrinol 5: 1-13, 2014.
    • (2014) Front Endocrinol , vol.5 , pp. 1-13
    • Root-Bernstein, R.1    Podufaly, A.2    Dillon, P.F.3
  • 120
    • 0025343003 scopus 로고
    • The functions of corticosteroid-binding globulin and sex hormone-binding globulin: Recent advances
    • Rosner W. The functions of corticosteroid-binding globulin and sex hormone-binding globulin:recent advances. Endocr Rev 11: 80-91, 1990.
    • (1990) Endocr Rev , vol.11 , pp. 80-91
    • Rosner, W.1
  • 121
    • 84862013849 scopus 로고    scopus 로고
    • Age ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion
    • Ross JJ, Howlett SE. Age ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion. PLos One 6: E38425, 2012.
    • (2012) PLos One , vol.6
    • Ross, J.J.1    Howlett, S.E.2
  • 122
    • 84912132943 scopus 로고    scopus 로고
    • Reconciling the divergent findings from clinical trials and observational studies of menopausal hormone therapy for prevention of coronary heart disease
    • Rossouw JE. Reconciling the divergent findings from clinical trials and observational studies of menopausal hormone therapy for prevention of coronary heart disease. Semin Reprod Med 32:426-432, 2014.
    • (2014) Semin Reprod Med , vol.32 , pp. 426-432
    • Rossouw, J.E.1
  • 123
    • 7144255732 scopus 로고
    • Estrogen formation by the human placenta: Studies on the mechanism of steroid aromatization by mammalian tissue
    • Ryan KJ. Estrogen formation by the human placenta:studies on the mechanism of steroid aromatization by mammalian tissue. Acta Endocrinol 35: 697-698, 1960.
    • (1960) Acta Endocrinol , vol.35 , pp. 697-698
    • Ryan, K.J.1
  • 124
    • 0016362969 scopus 로고
    • Placental biosynthesis and metabolism of steroid hormones in primates
    • Ryan KJ, Hopper BR. Placental biosynthesis and metabolism of steroid hormones in primates. Contrib Primatol 3: 258-283, 1974.
    • (1974) Contrib Primatol , vol.3 , pp. 258-283
    • Ryan, K.J.1    Hopper, B.R.2
  • 125
    • 0000340894 scopus 로고
    • Biogenesis of steroid hormones in the human ovary
    • Ryan KJ, Smith OW. Biogenesis of steroid hormones in the human ovary. Recent Prog Horm Res 21: 367-409, 1965.
    • (1965) Recent Prog Horm Res , vol.21 , pp. 367-409
    • Ryan, K.J.1    Smith, O.W.2
  • 126
    • 0021919589 scopus 로고
    • Gap junctions and myometrial steroid hormone receptors in pregnant and postpartum rats: A possible cellular bases for progesterone withdrawal hypothesis
    • Saito Y, Sakamoto H, MacLusky NJ, Naftolin F. Gap junctions and myometrial steroid hormone receptors in pregnant and postpartum rats: A possible cellular bases for progesterone withdrawal hypothesis. Am J Obstet Gynecol 151:805-812, 1985.
    • (1985) Am J Obstet Gynecol , vol.151 , pp. 805-812
    • Saito, Y.1    Sakamoto, H.2    MacLusky, N.J.3    Naftolin, F.4
  • 128
    • 67449136137 scopus 로고    scopus 로고
    • History of aromatase: Saga of an important biological mediator and therapeutic target
    • Santen RJ, Brodie H, Simpson ER, Siiteri PK, Brodie A. History of aromatase: Saga of an important biological mediator and therapeutic target. Endocr Rev 30: 343-375, 2009.
    • (2009) Endocr Rev , vol.30 , pp. 343-375
    • Santen, R.J.1    Brodie, H.2    Simpson, E.R.3    Siiteri, P.K.4    Brodie, A.5
  • 129
    • 0017704570 scopus 로고
    • Kinetic, hormonal and clinical studies with amnioglutethimide in breast cancer
    • Santen RJ, Samojlik E, Lipton A,. Kinetic, hormonal and clinical studies with amnioglutethimide in breast cancer. Cancer 39: S2948-S2958, 1977.
    • (1977) Cancer , vol.39 , pp. S2948-S2958
    • Santen, R.J.1    Samojlik, E.2    Lipton, A.3
  • 130
    • 84881489557 scopus 로고    scopus 로고
    • The mortality toll of estrogen avoidance: An analysis of excess deaths among hysterectomized women aged 50 to 59 years
    • Sarrel PM, Njike VY, Vinante V, Katz DL. The mortality toll of estrogen avoidance: An analysis of excess deaths among hysterectomized women aged 50 to 59 years. Am J Public Health 103: 1583-1588, 2013.
    • (2013) Am J Public Health , vol.103 , pp. 1583-1588
    • Sarrel, P.M.1    Njike, V.Y.2    Vinante, V.3    Katz, D.L.4
  • 135
    • 84858705877 scopus 로고    scopus 로고
    • Estrogen and cognitive functioning in women: Lessons we have learned
    • Sherwin BB. Estrogen and cognitive functioning in women: Lessons we have learned. Behav Neurosci 126: 123-127, 2012.
    • (2012) Behav Neurosci , vol.126 , pp. 123-127
    • Sherwin, B.B.1
  • 136
    • 0027295265 scopus 로고
    • Competitive product inhibition of aromatase by natural estrogens
    • Shimizu Y, Yarborough C, Osawa Y. Competitive product inhibition of aromatase by natural estrogens. J Steroid Biochem 44: 651-656, 1993.
    • (1993) J Steroid Biochem , vol.44 , pp. 651-656
    • Shimizu, Y.1    Yarborough, C.2    Osawa, Y.3
  • 137
    • 0025772011 scopus 로고
    • A new cause of female pseudohermaphroditism: Placental aromatase deficiency
    • Shozu M, Akasofu K, Harada T, Kubota Y. A new cause of female pseudohermaphroditism: Placental aromatase deficiency. J Clin Endocrinol Metab 72: 560-566, 1990.
    • (1990) J Clin Endocrinol Metab , vol.72 , pp. 560-566
    • Shozu, M.1    Akasofu, K.2    Harada, T.3    Kubota, Y.4
  • 139
  • 140
    • 0035961223 scopus 로고    scopus 로고
    • Estrogen and the aging brain
    • Silva I, Mor G, Naftolin F. Estrogen and the aging brain. Maturitas 38: 95-101, 2001.
    • (2001) Maturitas , vol.38 , pp. 95-101
    • Silva, I.1    Mor, G.2    Naftolin, F.3
  • 141
    • 84883888232 scopus 로고    scopus 로고
    • Brain health and cognitive and mood disorders in ageing women
    • Silva I, Naftolin F. Brain health and cognitive and mood disorders in ageing women. Best Pract Res Clin Obstet Gynaecol 27: 661-672, 2013.
    • (2013) Best Pract Res Clin Obstet Gynaecol , vol.27 , pp. 661-672
    • Silva, I.1    Naftolin, F.2
  • 142
    • 0242457714 scopus 로고    scopus 로고
    • Sources of estrogen and their importance
    • Simpson ER. Sources of estrogen and their importance. J Steroid Biochem 86: 225-230, 2003.
    • (2003) J Steroid Biochem , vol.86 , pp. 225-230
    • Simpson, E.R.1
  • 146
    • 0038210242 scopus 로고    scopus 로고
    • Aromatase inhibitors in breast cancer
    • Smith IE, Dowsett M. Aromatase inhibitors in breast cancer. N Engl J Med 348: 2431-2442, 2003.
    • (2003) N Engl J Med , vol.348 , pp. 2431-2442
    • Smith, I.E.1    Dowsett, M.2
  • 147
    • 0027459108 scopus 로고
    • Influence of age and menopause on serum lipids and lipoproteins in healthy women
    • Stevenson JC, Crook D, Godsland IF. Influence of age and menopause on serum lipids and lipoproteins in healthy women. Atherosclerosis 98: 83-90, 1993.
    • (1993) Atherosclerosis , vol.98 , pp. 83-90
    • Stevenson, J.C.1    Crook, D.2    Godsland, I.F.3
  • 148
    • 83655202585 scopus 로고    scopus 로고
    • Tissue physiology and pathology of aromatase
    • Stocco C. Tissue physiology and pathology of aromatase. Steroids 77: 27-35, 2012.
    • (2012) Steroids , vol.77 , pp. 27-35
    • Stocco, C.1
  • 149
  • 150
    • 0024253862 scopus 로고
    • Aromatase and nonaromatizing 10-demethylase activity of adrenal cortex mitochondrial P450(11)beta
    • Suhara K, Ohashi K, Takahashi K, Katagiri M. Aromatase and nonaromatizing 10-demethylase activity of adrenal cortex mitochondrial P450(11)beta. Arch Biochem Biophys 267: 31-37, 1988.
    • (1988) Arch Biochem Biophys , vol.267 , pp. 31-37
    • Suhara, K.1    Ohashi, K.2    Takahashi, K.3    Katagiri, M.4
  • 152
    • 67649472801 scopus 로고    scopus 로고
    • What can we learn from design faults in the Women’s Health Initiative randomized clinical trial?
    • Tan O, Harman SM, Naftolin F. What can we learn from design faults in the Women’s Health Initiative randomized clinical trial? Bull NYU Hosp Joint Dis 67: 226, 2009.
    • (2009) Bull NYU Hosp Joint Dis , vol.67 , pp. 226
    • Tan, O.1    Harman, S.M.2    Naftolin, F.3
  • 154
    • 0029794787 scopus 로고    scopus 로고
    • Diverse functions of aromatase: O-deethylation of 7-ethoxycoumarin
    • Toma Y, Higashiyama T, Yarborough C, Osawa Y. Diverse functions of aromatase: O-deethylation of 7-ethoxycoumarin. Endocrinology 137: 3791-3796, 1996.
    • (1996) Endocrinology , vol.137 , pp. 3791-3796
    • Toma, Y.1    Higashiyama, T.2    Yarborough, C.3    Osawa, Y.4
  • 155
    • 7544250772 scopus 로고    scopus 로고
    • Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans
    • Trösken ER, Scholz K, Lutz RW, Völkel W, Zarn JA, Lutz WK. Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res 30: 387-394, 2004.
    • (2004) Endocr Res , vol.30 , pp. 387-394
    • Trösken, E.R.1    Scholz, K.2    Lutz, R.W.3    Völkel, W.4    Zarn, J.A.5    Lutz, W.K.6
  • 157
    • 84938204297 scopus 로고    scopus 로고
    • Bariatric surgery and risk of postoperative endometrial cancer: A systematic review and meta-analysis
    • Upala S, Sanguankeo A. Bariatric surgery and risk of postoperative endometrial cancer: A systematic review and meta-analysis. Surg Obes Relat Dis 11: 949-955, 2015.
    • (2015) Surg Obes Relat Dis , vol.11 , pp. 949-955
    • Upala, S.1    Sanguankeo, A.2
  • 160
    • 84923205376 scopus 로고    scopus 로고
    • Kathleen Cuningham Foundation Consortium for Research into Familial Breast cancer, Lo C., Simpson E.R, Brown KA. Prostaglandin E2 inhibits P43 in human breast adipose stromal cells: A novel mechanism for the regulation of aromatase in obesity and breast cancer
    • Wang X, Docanto MM, Sasano H,. Kathleen Cuningham Foundation Consortium for Research into Familial Breast cancer, Lo C., Simpson E.R, Brown KA. Prostaglandin E2 inhibits P43 in human breast adipose stromal cells: A novel mechanism for the regulation of aromatase in obesity and breast cancer. Cancer Res 75: 645-655, 2015.
    • (2015) Cancer Res , vol.75 , pp. 645-655
    • Wang, X.1    Docanto, M.M.2    Sasano, H.3
  • 161
    • 84941190426 scopus 로고    scopus 로고
    • Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer
    • Wang X, Simpson ER, Brown KA. Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer. J Steroid Biochem 153: 35-44, 2015.
    • (2015) J Steroid Biochem , vol.153 , pp. 35-44
    • Wang, X.1    Simpson, E.R.2    Brown, K.A.3
  • 162
    • 0141480526 scopus 로고
    • The fate of the nontreated postmenopausal woman: A plea for the maintenance of adequate estrogen from puberty to the grave
    • Wilson RA, Wilson TA. The fate of the nontreated postmenopausal woman: A plea for the maintenance of adequate estrogen from puberty to the grave. J Am Geriatr Soc 11: 347-362, 1963.
    • (1963) J Am Geriatr Soc , vol.11 , pp. 347-362
    • Wilson, R.A.1    Wilson, T.A.2
  • 163
    • 0027987251 scopus 로고
    • Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism
    • Wooley CS, McEwen BS. Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. J Neurosci 14: 7680-7687, 1994.
    • (1994) J Neurosci , vol.14 , pp. 7680-7687
    • Wooley, C.S.1    McEwen, B.S.2
  • 164
    • 84930802617 scopus 로고    scopus 로고
    • Sex hormones and metabolic function
    • Yanase T, Tanabe M, Nomiyama T. Sex hormones and metabolic function. Nihon Rinsho 73: 571-575, 2015.
    • (2015) Nihon Rinsho , vol.73 , pp. 571-575
    • Yanase, T.1    Tanabe, M.2    Nomiyama, T.3
  • 165
  • 166
    • 0037381219 scopus 로고    scopus 로고
    • Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine
    • Yu AM, Idle JR, Krausz KW, Küpfer A, Gonzalez FJ. Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine. J Pharmacol Exp Ther 305: 315-322, 2003.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 315-322
    • Yu, A.M.1    Idle, J.R.2    Krausz, K.W.3    Küpfer, A.4    Gonzalez, F.J.5
  • 167
    • 0037024311 scopus 로고    scopus 로고
    • Steroid receptor coactivator-3 is required for inhabitation of neointima formation by estrogen
    • Yuan Y, Liao L, Tulis DA, Xu J. Steroid receptor coactivator-3 is required for inhabitation of neointima formation by estrogen. Circulation 105:2653-2659, 2002.
    • (2002) Circulation , vol.105 , pp. 2653-2659
    • Yuan, Y.1    Liao, L.2    Tulis, D.A.3    Xu, J.4
  • 168
    • 84943165102 scopus 로고    scopus 로고
    • Comparative study on individual aromatase inhibitors on cardiovascular safety profile: A network metaanalysis
    • Zhao Z, Liu L, Li K, Li W, Zhao L, Zou H. Comparative study on individual aromatase inhibitors on cardiovascular safety profile: A network metaanalysis. Onco Targets Ther 8: 2721-2730, 2015.
    • (2015) Onco Targets Ther , vol.8 , pp. 2721-2730
    • Zhao, Z.1    Liu, L.2    Li, K.3    Li, W.4    Zhao, L.5    Zou, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.