Neuroprotective effects of a novel non-receptor-binding estrogen analogue: In vitro and in vivo analysis

Stroke

Volumn 33, Issue 10, 2002, Pages 2485-2491

  Liu, Ran ^a   Yang, Shao Hua ^a   Perez, Evelyn ^a,b   Yi, Kun Don ^a   Wu, Samuel S ^c   Eberst, Kathleen ^b   Prokai, Laszlo ^b   Prokai Tatrai, Katalin ^b   Cai, Zu Yun ^d   Covey, Douglas F ^d   Day, Arthur L ^c   Simpkins, James W ^a,e  

^a UNIVERSITY OF NORTH FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d WASHINGTON UNIVERSITY   (United States)

^e UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Cerebral blood flow; Estrogens; Ischemia; Neuroprotection; Receptors, estrogen; Reperfusion injury

Indexed keywords

2 ADAMANTYLESTRA 1,3,5(10) TRIEN 3 OL 17 ONE; ESTRADIOL; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GLUTAMIC ACID; LIGAND; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG; ZYC 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; BINDING COMPETITION; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CELL ASSAY; CELL LINE; CELL VIABILITY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; FEMALE; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; HYDROGEN CLEARANCE; LIGAND BINDING; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; REPERFUSION; REPERFUSION INJURY; STAINING;

ADAMANTANE; ANIMALS; BINDING, COMPETITIVE; BLOOD FLOW VELOCITY; BRAIN; CELL LINE; CELL SURVIVAL; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; ESTRADIOL; ESTRADIOL CONGENERS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTRONE; FEMALE; GLUTAMIC ACID; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; LIGANDS; MICE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN;

EID: 0036790627     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000030317.43597.C8     Document Type: Article

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