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Volumn 6, Issue , 2016, Pages

Analysis of gene repair tracts from Cas9/gRNA double-stranded breaks in the human CFTR gene

Author keywords

[No Author keywords available]

Indexed keywords

CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GUIDE RNA;

EID: 84983803081     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep32230     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 0021234022 scopus 로고
    • Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA
    • Kucherlapati, R. S., Eves, E. M., Song, K. Y., Morse, B. S. & Smithies, O. Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA. Proc Natl Acad Sci USA 81(10), 3153-3157 (1984).
    • (1984) Proc Natl Acad Sci USA , vol.81 , Issue.10 , pp. 3153-3157
    • Kucherlapati, R.S.1    Eves, E.M.2    Song, K.Y.3    Morse, B.S.4    Smithies, O.5
  • 2
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas, K. R. & Capecchi, M. R. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51(3), 503-512 (1987).
    • (1987) Cell , vol.51 , Issue.3 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 3
    • 0028061666 scopus 로고
    • Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease
    • Rouet, P., Smih, F. & Jasin, M. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol. 14(12), 8096-8106 (1994).
    • (1994) Mol Cell Biol. , vol.14 , Issue.12 , pp. 8096-8106
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 4
    • 0031962185 scopus 로고    scopus 로고
    • Gene conversion tracts from double-strand break repair in mammalian cells
    • Elliott, B., Richardson, C., Winderbaum, J., Nickoloff, J. A. & Jasin, M. Gene conversion tracts from double-strand break repair in mammalian cells. Mol Cell Biol. 18(1), 93-101 (1998).
    • (1998) Mol Cell Biol. , vol.18 , Issue.1 , pp. 93-101
    • Elliott, B.1    Richardson, C.2    Winderbaum, J.3    Nickoloff, J.A.4    Jasin, M.5
  • 5
    • 18944373328 scopus 로고    scopus 로고
    • Highly efficient endogenous human gene correction using designed zinc-finger nucleases
    • Urnov, F. D. et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435(7042), 646-651 (2005).
    • (2005) Nature , vol.435 , Issue.7042 , pp. 646-651
    • Urnov, F.D.1
  • 6
    • 45349107029 scopus 로고    scopus 로고
    • The 'cutting edge' of gene therapy ⋯ literally Zinc-finger exercises
    • Segal, D. J. The 'cutting edge' of gene therapy ⋯ literally Zinc-finger exercises. The Biochemist E-volution 30, 10-13 (2008).
    • (2008) The Biochemist E-volution , vol.30 , pp. 10-13
    • Segal, D.J.1
  • 7
    • 84887010498 scopus 로고    scopus 로고
    • Genome engineering using the CRISPR-Cas9 system
    • Ran, F. A. et al. Genome engineering using the CRISPR-Cas9 system. Nat Protoc. 8(11), 2281-2308 (2013).
    • (2013) Nat Protoc. , vol.8 , Issue.11 , pp. 2281-2308
    • Ran, F.A.1
  • 8
    • 84930923547 scopus 로고    scopus 로고
    • Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells
    • Byrne, S. M., Ortiz, L., Mali, P., Aach, J. & Church, G. M. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Res. 43(3), e21 2015).
    • (2015) Nucleic Acids Res. , vol.43 , Issue.3 , pp. e21
    • Byrne, S.M.1    Ortiz, L.2    Mali, P.3    Aach, J.4    Church, G.M.5
  • 10
    • 85054130139 scopus 로고    scopus 로고
    • Correction of the Δ F508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair
    • Lee, C. M., Flynn, R., Hollywood, J. A., Scallan, M. F. & Harrison, P. T. Correction of the Δ F508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair. Biores Open Access 1(3), 99-108 (2012).
    • (2012) Biores Open Access , vol.1 , Issue.3 , pp. 99-108
    • Lee, C.M.1    Flynn, R.2    Hollywood, J.A.3    Scallan, M.F.4    Harrison, P.T.5
  • 11
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • Riordan, J. R. et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245(4922), 1066-1073 (1989).
    • (1989) Science , vol.245 , Issue.4922 , pp. 1066-1073
    • Riordan, J.R.1
  • 12
    • 84890033064 scopus 로고    scopus 로고
    • Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
    • Schwank, G. et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 13(6), 653-658 (2013).
    • (2013) Cell Stem Cell , vol.13 , Issue.6 , pp. 653-658
    • Schwank, G.1
  • 13
    • 84922059115 scopus 로고    scopus 로고
    • Nuclease-mediated double-strand break (DSB) enhancement of small fragment homologous recombination (SFHR) gene modification in human-induced pluripotent stem cells (hiPSCs)
    • Sargent, R. G., Suzuki, S. & Gruenert, D. C. Nuclease-mediated double-strand break (DSB) enhancement of small fragment homologous recombination (SFHR) gene modification in human-induced pluripotent stem cells (hiPSCs). Methods Mol Biol. 1114, 279-290 (2014).
    • (2014) Methods Mol Biol. , vol.1114 , pp. 279-290
    • Sargent, R.G.1    Suzuki, S.2    Gruenert, D.C.3
  • 14
    • 84933677842 scopus 로고    scopus 로고
    • Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells
    • Crane, A. M. et al. Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells. Stem Cell Reports. 4(4), 569-577 (2015).
    • (2015) Stem Cell Reports. , vol.4 , Issue.4 , pp. 569-577
    • Crane, A.M.1
  • 15
    • 84940793000 scopus 로고    scopus 로고
    • Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs
    • Firth, A. L. et al. Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs. Cell Rep. 12(9), 1385-1390 (2015).
    • (2015) Cell Rep. , vol.12 , Issue.9 , pp. 1385-1390
    • Firth, A.L.1
  • 16
    • 84975282868 scopus 로고    scopus 로고
    • Impact of gene editing on the study of cystic fibrosis
    • Epub ahead of print
    • Harrison, P. T., Sanz, D. J. & Hollywood, J. A. Impact of gene editing on the study of cystic fibrosis. Hum. Genet. Epub ahead of print, doi: 10.1007/s00439-016-1693-3 (2016).
    • (2016) Hum. Genet.
    • Harrison, P.T.1    Sanz, D.J.2    Hollywood, J.A.3
  • 17
    • 0027597730 scopus 로고
    • An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the delta F508 CFTR mutation
    • Kunzelmann, K. et al. An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the delta F508 CFTR mutation. Am J Respir Cell Mol Biol. 8(5), 522-529 (1993).
    • (1993) Am J Respir Cell Mol Biol. , vol.8 , Issue.5 , pp. 522-529
    • Kunzelmann, K.1
  • 18
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337(6096), 816-821 (2012).
    • (2012) Science , vol.337 , Issue.6096 , pp. 816-821
    • Jinek, M.1
  • 19
    • 84873734105 scopus 로고    scopus 로고
    • RNA-guided human genome engineering via Cas9
    • Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339(6121), 823-826 (2013).
    • (2013) Science , vol.339 , Issue.6121 , pp. 823-826
    • Mali, P.1
  • 20
    • 56649114274 scopus 로고    scopus 로고
    • A one pot, one step, precision cloning method with high throughput capability
    • Engler, C., Kandzia, R. & Marillonnet, S. A one pot, one step, precision cloning method with high throughput capability. PLoS One 3(11), e3647 (2008).
    • (2008) PLoS One , vol.3 , Issue.11
    • Engler, C.1    Kandzia, R.2    Marillonnet, S.3
  • 21
    • 84885157177 scopus 로고    scopus 로고
    • Optimization of scarless human stem cell genome editing
    • Yang, L. et al. Optimization of scarless human stem cell genome editing. Nucleic Acids Res. 41(19), 9049-9061 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , Issue.19 , pp. 9049-9061
    • Yang, L.1
  • 22
    • 84878127369 scopus 로고    scopus 로고
    • CFTR2: How will it help care?
    • Castellani, C. and CFTR2 team. CFTR2: How will it help care? Paediatr Respir Rev. 14 Suppl 1, 2-5 (2013).
    • (2013) Paediatr Respir Rev. , vol.14 , pp. 2-5
    • Castellani, C.1
  • 23
    • 14944374438 scopus 로고    scopus 로고
    • Distributions of exons and introns in the human genome
    • Sakharkar, M. K., Chow, V. T. & Kangueane, P. Distributions of exons and introns in the human genome. In Silico Biol. 4(4), 387-393 (2004).
    • (2004) Silico Biol. , vol.4 , Issue.4 , pp. 387-393
    • Sakharkar, M.K.1    Chow, V.T.2    Kangueane, P.3
  • 24
    • 84938836171 scopus 로고    scopus 로고
    • A genome-wide analysis of Cas9 binding specificity using ChIPseq and targeted sequence capture
    • O'Geen, H., Henry, I. M., Bhakta, M. S., Meckler, J. F. & Segal, D. J. A genome-wide analysis of Cas9 binding specificity using ChIPseq and targeted sequence capture. Nucleic Acids Res. 43(6), 3389-3404 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , Issue.6 , pp. 3389-3404
    • O'Geen, H.1    Henry, I.M.2    Bhakta, M.S.3    Meckler, J.F.4    Segal, D.J.5
  • 25
    • 84927514894 scopus 로고    scopus 로고
    • In vivo genome editing using Staphylococcus aureus Cas9
    • Ran, F. A. et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520(7546), 186-191 (2015).
    • (2015) Nature. , vol.520 , Issue.7546 , pp. 186-191
    • Ran, F.A.1
  • 26
    • 84884663630 scopus 로고    scopus 로고
    • Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
    • Hou, Z. et al. Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci USA 110, 15644-15649 (2013).
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 15644-15649
    • Hou, Z.1
  • 27
    • 84880581726 scopus 로고    scopus 로고
    • Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in
    • Popplewell, L. et al. Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in. Hum Gene Ther. 24(7), 692-701 (2013).
    • (2013) Hum Gene Ther. , vol.24 , Issue.7 , pp. 692-701
    • Popplewell, L.1
  • 28
    • 0028197257 scopus 로고
    • Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair
    • Nassif, N., Penney, J., Pal, S., Engels, W. R. & Gloor, G. B. Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair. Mol Cell Biol. 14(3), 1613-1625 (1994).
    • (1994) Mol Cell Biol. , vol.14 , Issue.3 , pp. 1613-1625
    • Nassif, N.1    Penney, J.2    Pal, S.3    Engels, W.R.4    Gloor, G.B.5
  • 29
    • 0028286906 scopus 로고
    • One-sided invasion events in homologous recombination at double-strand breaks
    • Belmaaza, A. & Chartrand, P. One-sided invasion events in homologous recombination at double-strand breaks. Mutat Res. 314(3), 199-208 (1994).
    • (1994) Mutat Res. , vol.314 , Issue.3 , pp. 199-208
    • Belmaaza, A.1    Chartrand, P.2
  • 30
    • 33847682924 scopus 로고    scopus 로고
    • Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
    • Moehle, E. A. et al. Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. Proc Natl Acad Sci USA 104(9), 3055-3060 (2007).
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.9 , pp. 3055-3060
    • Moehle, E.A.1
  • 31
    • 0032840461 scopus 로고    scopus 로고
    • Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast
    • Nickoloff, J. A., Sweetser, D. B., Clikeman, J. A., Khalsa, G. J. & Wheeler, S. L. Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast. Genetics 153(2), 665-679 (1999).
    • (1999) Genetics , vol.153 , Issue.2 , pp. 665-679
    • Nickoloff, J.A.1    Sweetser, D.B.2    Clikeman, J.A.3    Khalsa, G.J.4    Wheeler, S.L.5
  • 32
    • 38949107602 scopus 로고    scopus 로고
    • DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension
    • Maloisel, L., Fabre, F. & Gangloff, S. DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension. Mol Cell Biol. 28(4), 1373-1382 (2008).
    • (2008) Mol Cell Biol. , vol.28 , Issue.4 , pp. 1373-1382
    • Maloisel, L.1    Fabre, F.2    Gangloff, S.3
  • 33
    • 84924787370 scopus 로고    scopus 로고
    • Mismatch repair during homologous and homeologous recombination
    • Spies, M. & Fishel, R. Mismatch repair during homologous and homeologous recombination. Cold Spring Harb Perspect Biol. 7(3), a022657, doi: 10.1101/cshperspect.a022657 (2015).
    • (2015) Cold Spring Harb Perspect Biol. , vol.7 , Issue.3 , pp. a022657
    • Spies, M.1    Fishel, R.2
  • 34
    • 84964434798 scopus 로고    scopus 로고
    • Mechanism and regulation of DNA end resection in eukaryotes
    • Symington, L. S. Mechanism and regulation of DNA end resection in eukaryotes. Crit Rev Biochem Mol Biol. 51(3), 195-212 (2016).
    • (2016) Crit Rev Biochem Mol Biol. , vol.51 , Issue.3 , pp. 195-212
    • Symington, L.S.1
  • 35
    • 84896267457 scopus 로고    scopus 로고
    • Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair
    • Davis, L. & Maizels, N. Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair. Proc Natl Acad Sci USA 111(10), E924-E932 (2014).
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.10 , pp. E924-E932
    • Davis, L.1    Maizels, N.2
  • 36
    • 84896733529 scopus 로고    scopus 로고
    • Crystal structure of Cas9 in complex with guide RNA and target DNA
    • Nishimasu, H. et al. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell 156(5), 935-949 (2014).
    • (2014) Cell , vol.156 , Issue.5 , pp. 935-949
    • Nishimasu, H.1
  • 37
    • 84895871173 scopus 로고    scopus 로고
    • DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
    • Sternberg, S. H., Redding, S., Jinek, M., Greene, E. C. & Doudna, J. A. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.Nature 507(7490), 62-67 (2014).
    • (2014) Nature , vol.507 , Issue.7490 , pp. 62-67
    • Sternberg, S.H.1    Redding, S.2    Jinek, M.3    Greene, E.C.4    Doudna, J.A.5
  • 38
    • 84893157352 scopus 로고    scopus 로고
    • Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
    • Jinek, M. et al. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science 343(6176), 1247997 (2014).
    • (2014) Science , vol.343 , Issue.6176 , pp. 1247997
    • Jinek, M.1
  • 39
    • 84928948209 scopus 로고    scopus 로고
    • Genome Editing Technologies: Defining a Path to Clinic
    • Corrigan-Curay, J. et al. Genome Editing Technologies: Defining a Path to Clinic Molecular Therapy 23(5), 796-806 (2015).
    • (2015) Molecular Therapy , vol.23 , Issue.5 , pp. 796-806
    • Corrigan-Curay, J.1
  • 40
    • 1842366037 scopus 로고    scopus 로고
    • Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae
    • Pâques, F. & Haber, J. E. Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol. 17(11), 6765-6771 (1997).
    • (1997) Mol Cell Biol. , vol.17 , Issue.11 , pp. 6765-6771
    • Pâques, F.1    Haber, J.E.2
  • 41
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Pâques, F. & Haber, J. E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 63(2), 349-404 (1999).
    • (1999) Microbiol Mol Biol Rev. , vol.63 , Issue.2 , pp. 349-404
    • Pâques, F.1    Haber, J.E.2
  • 42
    • 36448991500 scopus 로고    scopus 로고
    • ClustalW and ClustalX version 2
    • Larkin, M. A. et al. ClustalW and ClustalX version 2. Bioinformatics 23(21), 2947-2948 (2007).
    • (2007) Bioinformatics , vol.23 , Issue.21 , pp. 2947-2948
    • Larkin, M.A.1


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