Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes

Clinical Epigenetics

Volumn 7, Issue 1, 2015, Pages

  Acevedo, Nathalie ^a,b   Reinius, Lovisa E ^b   Vitezic, Morana ^c   Fortino, Vittorio ^d   Söderhäll, Cilla ^b   Honkanen, Hanna ^e   Veijola, Riitta ^f   Simell, Olli ^g   Toppari, Jorma ^g   Ilonen, Jorma ^h   Knip, Mikael ^i,j,l   Scheynius, Annika ^a   Hyöty, Heikki ^e,k   Greco, Dario ^d   Kere, Juha ^b,l  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^e TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^f OULU UNIVERSITY HOSPITAL   (Finland)

^g TURKU UNIVERSITY HOSPITAL   (Finland)

^h UNIVERSITY OF TURKU   (Finland)

ⁱ UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^j TAMPERE UNIVERSITY HOSPITAL   (Finland)

^k FIMLAB LABORATORIES   (Finland)

^l UNIVERSITY OF HELSINKI   (Finland)

more..

Author keywords

Age modified CpG; Childhood; DNA methylation; Genes; Leukocytes; Longitudinal

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BETA ADRENERGIC RECEPTOR; CCAAT BINDING FACTOR; CLAUDIN 5; CONTACTIN 1; DECTIN 1; DEOXYRIBONUCLEASE I; DIACYLGLYCEROL KINASE; DISCOIDIN; E1A ASSOCIATED P300 PROTEIN; G PROTEIN COUPLED RECEPTOR KINASE 5; HISTONE DEACETYLASE 4; HLA DQ ANTIGEN; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; LEUCINE RICH REPEAT KINASE 2; MANNOSYLTRANSFERASE; NEUROGENIN 2; POLYCOMB GROUP PROTEIN; PROLINE RICH PROTEIN; PROTEIN MAD1; TENASCIN; TETRATRICOPEPTIDE REPEAT PROTEIN; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR YY1; TRIPARTITE MOTIF PROTEIN 5; TUBULIN; URIDINE PHOSPHORYLASE; ZINC FINGER PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; AGE; ANTIGEN PRESENTATION; ARID3A GENE; ARTICLE; BLOOD SAMPLING; CELL ADHESION; CELL LINEAGE; CELL MATURATION; CELL MEMBRANE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; CPG ISLAND; CYTOPLASM; DEMETHYLATION; DNA METHYLATION; DNA POLYMORPHISM; EPIGENETICS; FEMALE; FINLAND; GENE; GENE LOCUS; HAPLOTYPE; HDAC4 GENE; HISTONE MODIFICATION; HUMAN; HUMAN EXPERIMENT; INSULIN DEPENDENT DIABETES MELLITUS; IRF5 GENE; JARID2 GENE; KDM2A GENE; KDM2B GENE; LEUKOCYTE; MATERNAL SMOKING; NOD2 GENE; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROSPECTIVE STUDY; PROTEIN FOLDING; PTGER4 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SMARCD3 GENE; TRANSCRIPTION INITIATION SITE;

EID: 84983037030     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-015-0064-6     Document Type: Article

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