Distinctive topology of age-associated epigenetic drift in the human interactome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 35, 2013, Pages 14138-14143

  West, James ^a,b,c   Widschwendter, Martin ^a   Teschendorff, Andrew E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Department of Computer Science ^*  (United Kingdom)

^c Centre for Mathematics and Physics in the Life Sciences and Experimental Biology   (United Kingdom)

Author keywords

Aging; Biological networks; Epigenomics; Network topology

Indexed keywords

AGE DISTRIBUTION; AGING; ARTICLE; CELL FUNCTION; DISEASE PREDISPOSITION; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC DRIFT; HUMAN; INTERACTOME; LONGEVITY; MOLECULAR INTERACTION; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; STEM CELL; TRANSCRIPTION INITIATION SITE; 3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; GENETIC EPIGENESIS; GENETICS; METABOLISM;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; DNA METHYLATION; EPIGENESIS, GENETIC; GENETIC DRIFT; HUMANS; LONGEVITY; TRANSCRIPTION FACTORS;

EID: 84883321286     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1307242110     Document Type: Article

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