Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection

Veterinary Research

Volumn 47, Issue 1, 2016, Pages

  Fu, Shulin ^a,b   Xu, Lei ^a   Li, Sali ^a   Qiu, Yinsheng ^a,b   Liu, Yu ^a,b   Wu, Zhongyuan ^a,b   Ye, Chun ^a,b   Hou, Yongqing ^a,b   Hu, Chien An Andy ^c  

^a WUHAN POLYTECHNIC UNIVERSITY   (China)

^b Hubei Collaborative Innovation Centre for Animal Nutrition and Feed Safety   (China)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BAICALIN; CRYOPYRIN; CYTOKINE; FLAVONOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; REACTIVE OXYGEN METABOLITE;

ANIMAL; APOPTOSIS; DRUG EFFECTS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS PARASUIS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MONOCYTE; PHYSIOLOGY; PIG; SIGNAL TRANSDUCTION; SWINE DISEASES; VETERINARY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CYTOKINES; FLAVONOIDS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS PARASUIS; INFLAMMASOMES; MONOCYTES; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SWINE; SWINE DISEASES;

EID: 84982946544     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1186/s13567-016-0359-4     Document Type: Article

References (56)

1. Oliveira S, Pijoan C (2004) Haemophilus parasuis: new trends on diagnosis, epidemiology and control. Vet Microbiol 99:1-12
2. Rapp-Gabrielson VJ, Kocur GJ, Clark JT, Muir SK (1997) Haemophilus parasuis: immunity in swine after vaccination. Vet Med 92:83-90
3. Kielstein P, Rapp-Gabrielson VJ (1992) Designation of 15 serovars of Haemophilus parasuis on the basis of immunodiffusion using heat-stable antigen extracts. J Clin Microbiol 30:862-865
4. Aragon V (2013) Exposing serum susceptibility in Haemophilus parasuis. Vet J 196:10-11
5. Costa-Hurtado M, Aragon V (2013) Advances in the quest for virulence factors of Haemophilus parasuis. Vet J 198:571-576
6. Costa-Hurtado M, Olvera A, Martinez-Moliner V, Galofré-Milà N, Martínez P, Dominguez J, Aragon V (2013) Changes in macrophage phenotype after infection of pigs with Haemophilus parasuis strains with different levels of virulence. Infect Immun 81:2327-2333
7. Bouchet B, Vanier G, Jacques M, Gottschalk M (2008) Interactions of Haemophilus parasuis and its LOS with porcine brain microvascular endothelial cells. Vet Res 39:42
8. Bouchet B, Vanier G, Jacques M, Auger E, Gottschalk M (2009) Studies on the interactions of Haemophilus parasuis with porcine epithelial tracheal cells: limited role of LOS in apoptosis and pro-inflammatory cytokine release. Microb Pathog 46:108-113
9. Chen Y, Jin H, Chen P, Li Z, Meng X, Liu M, Li S, Shi D, Xiao Y, Wang X, Zhou Z, Bi D, Zhou R (2012) Haemophilus parasuis infection activates the NF-κB pathway in PK-15 cells through IκB degradation. Vet Microbiol 160:259-263
10. Chen Y, Liu T, Langford P, Hua K, Zhou S, Zhai Y, Xiao H, Luo R, Bi D, Jin H, Zhou R (2015) Haemophilus parasuis induces activation of NF-κB and MAP kinase signaling pathways mediated by toll-like receptors. Mol Immunol 65:360-366
11. Vallabhapurapu S, Karin M (2009) Regulation and function of NF-κB transcription factors in the immune system. Annu Rev Immunol 27:693-733
12. Mussá T, Rodríguez-Cariño C, Sánchez-Chardi A, Baratelli M, Costa-Hurtado M, Fraile L, Domínguez J, Aragon V, Montoya M (2012) Differential interactions of virulent and non-virulent H. parasuis strains with naïve or swine influenza virus pre-infected dendritic cells. Vet Res 43:80
13. Lukens JR, Gross JM, Kanneganti TD (2012) IL-1 family cytokines trigger sterile inflammatory disease. Front Immunol 3:315
14. Latz E, Xiao TS, Stutz A (2013) Activation and regulation of the inflammasomes. Nat Rev Immunol 13:397-411
15. Liu P, Xie Q, Wei T, Chen Y, Chen H, Shen W (2015) Activation of the NLRP3 inflammasome induces vascular dysfunction in obese OLETF rats. Biochem Biophys Res Commun 468:319-325
16. Shao BZ, Xu ZQ, Han BZ, Su DF, Liu C (2015) NLRP3 inflammasome and its inhibitors: a review. Front Pharmacol 6:262
17. Phongsisay V (2016) The immunobiology of Campylobacter jejuni: innate immunity and autoimmune diseases. Immunobiology 221:535-543
18. Liu Y, Yao W, Xu J, Qiu Y, Cao F, Li S, Yang S, Yang H, Wu Z, Hou Y (2015) The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes. Innate Immun 21:587-597
19. Ye C, Li S, Yao W, Xu L, Qiu Y, Liu Y, Wu Z, Hou Y (2016) The anti-inflammatory effects of baicalin through suppression of NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes. Innate Immun 22:196-224
20. Granata S, Masola V, Zoratti E, Scupoli MT, Baruzzi A, Messa M, Sallustio F, Gesualdo L, Lupo A, Zaza G (2015) NLRP3 inflammasome activation in dialyzed chronic kidney disease patients. PLoS One 10:e0122272
21. Zhong Z, Zhai Y, Liang S, Mori Y, Han R, Sutterwala FS, Qiao L (2013) TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun 4:1611
22. Guarda G, Zenger M, Yazdi AS, Schroder K, Ferrero I, Menu P, Tardivel A, Mattmann C, Tschopp J (2011) Differential expression of NLRP3 among hematopoietic cells. J Immunol 186:2529-2534
23. Wen H, Ting JP, O'Neill LA (2012) A role for the NLRP3 inflammasome in metabolic diseases-did Warburg miss inflammation? Nat Immunol 13:352-357
24. Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A, Muruve D, Shi Y, Munro F, Liapis H, Anders HJ (2013) Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion. J Clin Invest 123:236-246
25. Jeong HS, Gu GE, Jo AR, Bang JS, Yun HY, Baek KJ, Kwon NS, Park KC, Kim DS (2015) Baicalin-induced Akt activation decreases melanogenesis through downregulation of microphthalmia-associated transcription factor and tyrosinase. Eur J Pharmacol 761:19-27
26. Shieh DE, Liu LT, Lin CC (2000) Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res 20:2861-2865
27. Chen H, Xu Y, Wang J, Zhao W, Ruan H (2015) Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat. Int J Clin Exp Pathol 8:10139-10147
28. Chu M, Xu L, Zhang MB, Chu ZY, Wang YD (2015) Role of baicalin in anti-influenza virus A as a potent inducer of IFN-Gamma. Biomed Res Int 2015:263630
29. Moghaddam E, Teoh BT, Sam SS, Lani R, Hassandarvish P, Chik Z, Yueh A, Abubakar S, Zandi K (2014) Baicalin, a metabolite of baicalein with antiviral activity against dengue virus. Sci Rep 4:5452
30. Wang T, Shi G, Shao J, Wu D, Yan Y, Zhang M, Cui Y, Wang C (2015) In vitro antifungal activity of baicalin against Candida albicans biofilms via apoptotic induction. Microb Pathog 87:21-29
31. Yu Y, Pei M, Li L (2015) Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo. Int J Clin Exp Med 8:8958-8967
32. Dong SJ, Zhong YQ, Lu WT, Li GH, Jiang HL, Mao B (2015) Baicalin inhibits lipopolysaccharide-induced inflammation through signaling NF-κB pathway in HBE16 airway epithelial cells. Inflammation 38:1493-1501
33. Liu T, Dai W, Li C, Liu F, Chen Y, Weng D, Chen J (2015) Baicalin alleviates silica-induced lung inflammation and fibrosis by inhibiting the Th17 response in C57BL/6 mice. J Nat Prod 78:3049-3057
34. Min W, Ahmad I, Chang ME, Burns EM, Qian Q, Yusuf N (2015) Baicalin protects keratinocytes from toll-like receptor-4 mediated DNA damage and inflammation following ultraviolet irradiation. Photochem Photobiol 91:1435-1443
35. Chen G, Feng W, Zhang S, Bian K, Yang Y, Fang C, Chen M, Yang J, Zou X (2015) Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signaling. Am J Cancer Res 5:1423-1434
36. Shafagh M, Rahmani F, Delirezh N (2015) CuO nanoparticles induce cytotoxicity and apoptosis in human K562 cancer cell line via mitochondrial pathway, through reactive oxygen species and P53. Iran J Basic Med Sci 18:993-1000
37. Kavanová L, Prodělalová J, Nedbalcová K, Matiašovic J, Volf J, Faldyna M, Salát J (2015) Immune response of porcine alveolar macrophages to a concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in vitro. Vet Microbiol 180:28-35
38. Macedo N, Rovira A, Torremorell M (2015) Haemophilus parasuis: infection, immunity and enrofloxacin. Vet Res 46:128
39. Liu C, Wang Y, Zhang H, Cheng S, Charreyre C, Audonnet JC, Chen P, He Q (2014) Porcine coronin 1A contributes to nuclear factor-kappa B (NF-κB) inactivation during Haemophilus parasuis infection. PLoS One 9:e103904
40. Chen Y, Zhou S, Hua K, Xiao H, Li Z, Liu M, Luo R, Bi D, Zhou R, Jin H (2015) Haemophilus parasuis infection activates chemokine RANTES in PK-15 cells. Mol Immunol 67:661-666
41. Zhou S, He X, Xu C, Zhang B, Feng S, Zou Y, Li J, Liao M (2014) The outer membrane protein P2 (OmpP2) of Haemophilus parasuis induces proinflammatory cytokine mRNA expression in porcine alveolar macrophages. Vet J 199:461-464
42. Frandoloso R, Pivato M, Martínez-Martínez S, Rodríguez-Ferri EF, Kreutz LC, Martín CB (2013) Differences in Haemophilus parasuis adherence to and invasion of AOC-45 porcine aorta endothelial cells. BMC Vet Res 9:207
43. Verstrepen L, Bekaert T, Chau TL, Tavernier J, Chariot A, Beyaert R (2008) TLR-4, IL-1R and TNF-R signaling to NF-kappa B: variations on a common theme. Cell Mol Life Sci 65:2964-2978
44. Ka SM, Kuoping Chao L, Lin JC, Chen ST, Li WT, Lin CN, Cheng JC, Jheng HL, Chen A, Hua KF (2016) A low toxicity synthetic cinnamaldehyde derivative ameliorates renal inflammation in mice by inhibiting NLRP3 inflammasome and its related signaling pathways. Free Radic Biol Med 91:10-24
45. Li W, Suwanwela NC, Patumraj S (2016) Curcumin by down regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R. Microvasc Res 106:117-127
46. Kaphalia L, Kalita M, Kaphalia BS, Calhoun WJ (2016) Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells. Toxicol Appl Pharmacol 292:85-93
47. Broz P (2015) Inflammasome assembly: the wheels are turning. Cell Res 25:1277-1278
48. Benetti E, Chiazza F, Patel NS, Collino M (2013) The NLRP3 inflammasome as a novel player of the intercellular crosstalk in metabolic disorders. Mediators Inflamm 2013:678627
49. Xiang Y, Wang X, Yan C, Gao Q, Li SA, Liu J, Zhou K, Guo X, Lee W, Zhang Y (2013) Adenosine-5′-triphosphate (ATP) protects mice against bacterial infection by activation of the NLRP3 inflammasome. PLoS One 8:e63759
50. Weinheimer-Haus EM, Mirza RE, Koh TJ (2015) Nod-like receptor protein-3 inflammasome plays an important role during early stages of wound healing. PLoS One 10:e0119106
51. Qiao J, Huang Y, Xia Y, Chu P, Yao H, Xu L, Qi K, Liu Y, Xu K, Zeng L (2015) Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation. Sci Rep 5:17828
52. Filardy AA, He J, Bennink J, Yewdell J, Kelsall BL (2016) Posttranscriptional control of NLRP3 inflammasome activation in colonic macrophages. Mucosal Immunol 9:850-858
53. Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, Ojcius DM (2007) ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem 282:2871-2879
54. Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, Franchi L, Uematsu S, Sagara J, Taniguchi S, Tsutsui H, Akira S, Tschopp J, Núñez G, Suzuki T (2010) Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling. J Immunol 184:5287-5297
55. Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, Zhao H, Ren Z, Xu J (2012) Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1β in human macrophages and EHEC-induced IL-1β required activation of NLRP3 inflammasome. PLoS One 7:e50288
56. Bouwman LI, de Zoete MR, Bleumink-Pluym NM, Flavell RA, van Putten JP (2014) Inflammasome activation by Campylobacter jejuni. J Immunol 193:4548-4557