Changes in macrophage phenotype after infection of pigs with haemophilus parasuis strains with different levels of virulence

Infection and Immunity

Volumn 81, Issue 7, 2013, Pages 2327-2333

  Costa Hurtado, Mar ^a   Olvera, Alexandre ^a,b,e   Martinez Moliner, Verónica ^a   Galofré Milà, Nuria ^a   Martínez, Paloma ^c   Dominguez, Javier ^c   Aragon, Virginia ^a,d  

^a CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INIA   (Spain)

^d IRTA   (Spain)

^e HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD14 ANTIGEN; CD163 ANTIGEN; INTERLEUKIN 8; SIALOADHESIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; CONTROLLED STUDY; HAEMOPHILUS INFECTION; HAEMOPHILUS PARASUIS; HOST PATHOGEN INTERACTION; INOCULATION; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; NOSE CAVITY; PHAGOCYTOSIS; PHENOTYPE; PIGLET; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL SHAPE; CHO CELLS; CRICETINAE; DISEASE MODELS, ANIMAL; HAEMOPHILUS INFECTIONS; HAEMOPHILUS PARASUIS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HOST-PATHOGEN INTERACTIONS; INTERFERON-ALPHA; INTERLEUKIN-8; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; PHENOTYPE; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIALIC ACID BINDING IG-LIKE LECTIN 1; SWINE; SWINE DISEASES; VIRULENCE;

EID: 84879456412     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00056-13     Document Type: Article

References (32)

1. Aragon V, Segales J, Oliveira S. 2012. Glässer's disease, p 760-769. In Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, StevensonGW(ed), Diseases of swine, 10th ed. Wiley-Blackwell, Ames, Iowa.
2. Holtkamp D, Rotto H, Garcia R. 2007. Economic cost of major health challenges in large US swine production systems. Swine News 30:85- 89.
3. Vahle JL, Haynes JS, Andrews JJ. 1995. Experimental reproduction of Haemophilus parasuis infection in swine: clinical, bacteriological, and morphologic findings. J. Vet. Diagn. Invest. 7:476-480.
4. Rosenberger CM, Finlay BB. 2003. Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nat. Rev. Mol. Cell Biol. 4:385-396.
5. Chamorro S, Revilla C, Alvarez B, Lopez-Fuertes L, Ezquerra A, Dominguez J. 2000. Phenotypic characterization of monocyte subpopulations in the pig. Immunobiology 202:82-93.
6. Ezquerra A, Revilla C, Alvarez B, Perez C, Alonso F, Dominguez J. 2009. Porcine myelomonocytic markers and cell populations. Dev. Comp. Immunol. 33:284 -298.
7. Rutherford MS, Witsell A, Schook LB. 1993. Mechanisms generating functionally heterogeneous macrophages: chaos revisited. J. Leukoc. Biol. 53:602- 618.
8. Olvera A, Ballester M, Nofrarias M, Sibila M, Aragon V. 2009. Differences in phagocytosis susceptibility in Haemophilus parasuis strains. Vet. Res. 40:24.
9. Wang Y, Liu C, Fang Y, Liu X, Li W, Liu S, Liu Y, Liu Y, Charreyre C, Audonnet JC, Chen P, He Q. 2012. Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis. BMC Genomics 13:68.
10. Wilkinson JM, Sargent CA, Galina-Pantoja L, Tucker AW. 2010. Gene expression profiling in the lungs of pigs with different susceptibilities to Glasser's disease. BMC Genomics 11:455.
11. Aragon V, Cerda-Cuellar M, Fraile L, Mombarg M, Nofrarias M, Olvera A, Sibila M, Solanes D, Segales J. 2010. Correlation between clinicopathological outcome and typing of Haemophilus parasuis field strains. Vet. Microbiol. 142:387-393.
12. Kielstein P, Rapp-Gabrielson VJ. 1992. Designation of 15 serovars of Haemophilus parasuis on the basis of immunodiffusion using heat-stable antigen extracts. J. Clin. Microbiol. 30:862- 865.
13. Martínez-Moliner V, Soler-Llorens P, Moleres J, Garmendia J, Aragon V. 2012. Distribution of genes involved in sialic acid utilization in strains of Haemophilus parasuis. Microbiology 158:2117-2124.
14. Fabriek BO, van Bruggen R, Deng DM, Ligtenberg AJ, Nazmi K, Schornagel K, Vloet RP, Dijkstra CD, van den Berg TK. 2009. The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria. Blood 113:887- 892.
15. Oldenborg PA, Gresham HD, Lindberg FP. 2001. CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. J. Exp. Med. 193:855- 862.
16. Taylor PR, Martinez-Pomares L, Stacey M, Lin HH, Brown GD, Gordon S. 2005. Macrophage receptors and immune recognition. Annu. Rev. Immunol. 23:901-944.
17. Van Amersfoort ES, Van Berkel TJ, Kuiper J. 2003. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin. Microbiol. Rev. 16:379-414.
18. Chamorro S, Revilla C, Alvarez B, Alonso F, Ezquerra A, Dominguez J. 2005. Phenotypic and functional heterogeneity of porcine blood monocytes and its relation with maturation. Immunology 114:63-71.
19. Feng L, Zhou X, Su LX, Feng D, Jia YH, Xie LX. 2012. Clinical significance of soluble hemoglobin scavenger receptor CD163 (sCD163) in sepsis, a prospective study. PLoS One 7:e38400. doi:10.1371/journal .pone.0038400.
20. Perez C, Ortuño E, Gomez N, García-Briones M, Alvarez B, Martínez de la Riva P, Alonso F, Revilla C, Domínguez J, Ezquerra A. 2008. Cloning and expression of porcine CD163: its use for characterization of monoclonal antibodies to porcine CD163 and development of an ELISA to measure soluble CD163 in biological fluids. Span. J. Agric. Res. 6:59 -72.
21. González-Navajas JM, Lee J, David M, Raz E. 2012. Immunomodulatory functions of type I interferons. Nat. Rev. Immunol. 12:125-135.
22. Diaz de Arce H, Artursson K, L'Haridon R, Perers A, La Bonnardiere C, Alm GV. 1992. A sensitive immunoassay for porcine interferon-alpha. Vet. Immunol. Immunopathol. 30:319 -327.
23. Guzylack-Piriou L, Balmelli C, McCullough KC, Summerfield A. 2004. Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-alpha, tumour necrosis factoralpha and interleukin-12. Immunology 112:28 -37.
24. Costa-Hurtado M, Ballester M, Galofre-Mila N, Darji A, Aragon V. 2012. VtaA8 and VtaA9 from Haemophilus parasuis delay phagocytosis by alveolar macrophages. Vet. Res. 43:57.
25. Celli J, Finlay BB. 2002. Bacterial avoidance of phagocytosis. Trends Microbiol. 10:232-237.
26. Sharma A, Qadri A. 2004. Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses. Proc. Natl. Acad. Sci. U. S. A. 101: 17492-17497.
27. Martín de la Fuente AJ, Gutierrez-Martin CB, Rodriguez-Barbosa JI, Martinez-Martinez S, Frandoloso R, Tejerina F, Rodriguez-Ferri EF. 2009. Blood cellular immune response in pigs immunized and challenged with Haemophilus parasuis. Res. Vet. Sci. 86:230 -234.
28. Møller HJ. 2012. Soluble CD163. Scand. J. Clin. Lab. Invest. 72:1-13.
29. Davis BH, Zarev PV. 2005. Human monocyte CD163 expression inversely correlates with soluble CD163 plasma levels. Cytometry B Clin. Cytom. 63:16 -22.
30. Hintz KA, Rassias AJ, Wardwell K, Moss ML, Morganelli PM, Pioli PA, Givan AL, Wallace PK, Yeager MP, Guyre PM. 2002. Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163. J. Leukoc. Biol. 72:711-717.
31. Weaver LK, Hintz-Goldstein KA, Pioli PA, Wardwell K, Qureshi N, Vogel SN, Guyre PM. 2006. Pivotal advance: activation of cell surface Toll-like receptors causes shedding of the hemoglobin scavenger receptor CD163. J. Leukoc. Biol. 80:26 -35.
32. Theofilopoulos AN, Baccala R, Beutler B, Kono DH. 2005. Type I interferons (alpha/beta) in immunity and autoimmunity. Annu. Rev. Immunol. 23:307-336.