The anti-inflammatory effects of acetaminophen and N -acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes

Innate Immunity

Volumn 21, Issue 6, 2015, Pages 587-597

  Liu, Yu ^a,b   Yao, Wenxu ^a   Xu, Jun ^a   Qiu, Yinsheng ^a,b   Cao, Fangyuan ^a   Li, Sali ^a   Yang, Sheng ^a   Yang, Hailan ^a   Wu, Zhongyuan ^a   Hou, Yongqing ^a,b  

^a WUHAN POLYTECHNIC UNIVERSITY   (China)

^b Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety   (China)

Author keywords

Acetaminophen; anti inflammation; caspase 1; N acetylcysteine; NLRP3 inflammasome

Indexed keywords

ACETYLCYSTEINE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; PARACETAMOL; ANTIINFLAMMATORY AGENT; CARRIER PROTEIN; DRUG COMBINATION;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; IN VITRO STUDY; INFLAMMATION; MONONUCLEAR PHAGOCYTE; NONHUMAN; PIGLET; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG COMBINATION; DRUG EFFECTS; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PIG;

ACETAMINOPHEN; ACETYLCYSTEINE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; DRUG COMBINATIONS; DRUG SYNERGISM; GENE EXPRESSION REGULATION; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MONONUCLEAR PHAGOCYTE SYSTEM; SWINE;

EID: 84936139455     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425914566205     Document Type: Article

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