Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

Toxicology and Applied Pharmacology

Volumn 292, Issue , 2016, Pages 85-93

  Kaphalia, Lata ^a   Kalita, Mridul ^a   Kaphalia, Bhupendra S ^a   Calhoun, William J ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Acetaldehyde; AMPK signaling; Cytokines; Ethanol; Fatty acid ethyl esters; Human airway smooth muscle cells

Indexed keywords

ALCOHOL; CYTOKINE;

BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; HUMAN; LUNG; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY; SMOOTH MUSCLE CELL;

CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HUMANS; LUNG; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS;

EID: 84953897754     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.12.011     Document Type: Article

References (43)

1. Berild D., Hasselbalch H. Survival after a blood alcohol of 1127mg/dL. Lancet 1981, 2:363.
2. Boé D.M., Vandivier R.W., Burnham E.L., Moss M. Alcohol abuse and pulmonary disease. J. Leukoc. Biol. 2009, 86:1097-1104.
3. Cederbaum A.I. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity. Digest Dis. 2010, 28:802-811.
4. Christoloupos G., Kirch E.R., Gearien J.E. Determination of ethanol in fresh and putrefied post mortem tissues. J. Chromatogr. 1973, 87:455-472.
5. Chung K.F. Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation. Eur. Respir. J. 2005, 15:961-968.
6. Cook R.T. Alcohol abuse, alcoholism, and damage to the immune system - a review. Alcohol. Clin. Exp. Res. 1998, 22:1927-1942.
7. D'Souza El-Guindy N.B., de Villiers W.J., Doherty D.E. Acute alcohol intake impairs lung inflammation by changing pro- and anti-inflammatory mediator balance. Alcohol 2007, 41:335-345.
8. García-Villafranca J., Guillén A.J., Me C. Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver. Biochimie 2008, 90:460-466.
9. Guedes A.G., Deshpande D.A., Dileepan M., Walseth T.F., Panettieri R.A., Subramanian S., Kannan M.S. CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models. Can. J. Physiol. Pharmacol. 2015, 93:145-153.
10. Hammond K.B., Rumack B.H., Rodgerson D.O. Blood ethanol. J. Am. Med. Assoc. 1973, 226:63-64.
11. Hawley S.A., Davison M., Woods A., Davies S.P., Beri R.K., Carling D., Hardie D.G. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J. Biol Chem. 1996, 271:27879-27887.
12. Howarth P.H., Knox A.J.Y., Amrani O., Tliba R.A., Panettieri R.A., Johnson M. Synthetic responses in airway smooth muscle. J. Allergy Clin. Immunol. 2004, 114:S32-S50.
13. Johnson S.R., Knox A.J. Synthetic functions of airway smooth muscle in asthma. Trends Pharmacol. Sci. 1997, 18:288-292.
14. Kalita M., Tian B., Gao B., Choudhary S., Wood T.G., Carmical J.R., Boldogh I., Mitra S., Minna J.D., Brasier A.R. Systems approaches to modeling chronic mucosal inflammation. Biomed. Res. Int. 2013, 505864.
15. Kaphalia L., Calhoun W.J. Alcoholic lung injury: metabolic, biochemical and immunological aspects. Toxicol. Lett. 2013, 222:171-179.
16. Kaphalia B.S., Cai P., Khan M.F., Okorodudu A.O., Ansari G.A.S. Fatty acid ethyl esters: markers of alcohol abuse and alcoholism. Alcohol 2004, 34:151-158.
17. Kaphalia L., Ju H., Kaphalia B.S., Calhoun W.J. Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding. Toxicol. Appl. Pharmacol. 2014, 277:109-117.
18. Lazaar A.L., Panettieri R.A. Airway smooth muscle: a modulator of airway remodeling in asthma. J. Allergy Clin. Immunol. 2005, 116:488-495.
19. Lieber C.S. Ethanol metabolism, cirrhosis and alcoholism. Clin. Chim. Acta 1997, 257:59-84.
20. Lindblad B., Olsson R. Unusually high levels of blood alcohol. J. Am. Med. Assoc. 1951, 236:1600-1602.
21. Manautou J.E., Carlson G.P. Ethanol-induced fatty acid ethyl ester formation in vivo and in vitro in rat lung. Toxicology 1991, 70:303-312.
22. Manautou J., Buss N., Carlson G.P. Oxidative and non-oxidative metabolism of ethanol by the rabbit lung. Toxicol. Lett. 1992, 62:93-99.
23. Moss M. Epidemiology of sepsis: race, sex, and chronic alcohol abuse. Clin. Infect. Dis. 2005, 41(Suppl. 7):S490-S497.
24. Moss M., Burnham E.L. Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction. Crit. Care Med. 2003, 31:S207-S212.
25. Moss M., Bucher B., Moore F.A., Moore E.E., Parsons P.E. The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults. J. Am. Med. Assoc. 1996, 275:50-54.
26. Nishiguchi M., Kinoshita H., Mostofa J., Taniguchi T., Ouchi H., Minami T., Hatake K., Utsumi T., Motomura H., Hishida S. Different blood acetaldehyde concentration following ethanol administration in a newly developed high alcohol preference and low alcohol preference rat model system. Alcohol Alcohol. 2002, 37:9-12.
27. Nuutinen H., Lindros K.O., Salaspuro M. Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics. Alcohol. Clin. Exp. Res. 1983, 7:163-168.
28. Oldenburg P.J., Wyatt T.A., Sission J.H. Ethanol attenuates contraction of primary cultured rat airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 2010, 43:539-545.
29. Panes J., Soler X., et al. Influence of liver disease on hepatic alcohol and aldehyde dehydrogenases. Gastroenterology 1989, 97:708-712.
30. Panes J., Caballeria J., et al. Determinants of ethanol and acetaldehyde metabolism in chronic alcoholics. Alcohol. Clin. Exp. Res. 1993, 17:48-53.
31. Rubenfeld G.D., Caldwell E., Peabody E., Weaver J., Martin D.P., Neff M., Stern E.J., Hudson L.D. Incidence and outcomes of acute lung injury. N. Engl. J. Med. 2005, 353:1685-1693.
32. Schmitt J.M., Wayman G.A., Nozaki N., Soderling T.R. Calcium activation of ERK mediated by calmodulin kinase I. J. Biol. Chem. 2004, 279:24064-24072.
33. Schug T.T., Li X. Sirtuin 1 in lipid metabolism and obesity. Ann. Med. 2011, 43:198-211.
34. Session J.H. Alcohol and airway function in health and disease. Alcohol 2007, 41:293-307.
35. Stoltz D.A., Nelson S., Kolls J.K., Zhang P., Bohm R.P., Murphey-Corb M., Bagby G.J. In vitro ethanol suppresses alveolar macrophage TNF-alpha during simian immunodeficiency virus infection. Am. J. Respir. Crit. Care Med. 2000, 161:135-140.
36. Szabo G., Catalano D., White B., Mandrekar P. Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells. Alcohol. Clin. Exp. Res. 2004, 28:824-828.
37. Tabak C., Smit H.A., Räsänen L., Fidanza F., Menotti A., Nissinen A., Feskens E.J., Heederik D., Kromhout D. Alcohol consumption in relation to 20-year COPD mortality and pulmonary function in middle-aged men from three European countries. Epidemiology 2001, 12(2):239-245.
38. Taieb J., Delarche C., Ethuin F., Saphia S., Poynard T. Ethanol-induced inhibition of cytokine release and protein degranulation in human neutrophils. J. Leukoc. Biol. 2002, 72:1142-1147.
39. Thorley A.J., Ford P.A., Giembycz M.A., Goldstraw P., Young A., Tanjore H. Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages. J. Immunol. 2007, 178:463-473.
40. 2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2005, 2:21-33.
41. Wu H., Ca P., Clemens D.L., Jerrells T.R., Ansari G.A.S., Kaphalia B.S. Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism. Toxicol. Appl. Pharmacol. 2006, 216:238-247.
42. You M., Matsumoto M., Pacold C.M., Cho W.K., Crabb D.W. The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology 2004, 127:1798-1808.
43. Zhao X., Zmijewsk J.W., Lorne E., Liu G., Park Y.J., Tsuruta Y., Abraham E. Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. Am. J. Physiol. Lung Cell Mol. 2008, 295:L497-L504.