Aging and peripheral lipopolysaccharide can modulate epigenetic regulators and decrease IL-1β promoter DNA methylation in microglia

Neurobiology of Aging

Volumn 47, Issue , 2016, Pages 1-9

  Matt, Stephanie M ^a   Lawson, Marcus A ^a   Johnson, Rodney W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Aging; DNA methylation; Interleukin 1 beta; Microglia; Neuroinflammation

Indexed keywords

CRYOPYRIN; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; HISTONE DEACETYLASE 1; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; AZACITIDINE; IL1B PROTEIN, MOUSE;

ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASP1 GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA METHYLATION; EPIGENETICS; GENE; GENE EXPRESSION; IL 1RN GENE; ILLNESS BEHAVIOR; MICROGLIA; MOUSE; NLRP3 GENE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

AGING; ANIMALS; AZACITIDINE; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE, INBRED C57BL; MICROGLIA; PROMOTER REGIONS, GENETIC;

EID: 84982733749     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.07.006     Document Type: Article

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