-
1
-
-
23044456776
-
Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans
-
Frasca D, Riley RL, Blomberg BB. Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans. Semin Immunol. 2005;17:378-84.
-
(2005)
Semin Immunol
, vol.17
, pp. 378-384
-
-
Frasca, D.1
Riley, R.L.2
Blomberg, B.B.3
-
2
-
-
84876535364
-
Understanding immunosenescence to improve responses to vaccines
-
Goronzy JJ, Weyand CM. Understanding immunosenescence to improve responses to vaccines. Nat Immunol. 2013;14:428-36.
-
(2013)
Nat Immunol
, vol.14
, pp. 428-436
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
3
-
-
33646546302
-
Aging of the immune system: how much can the adaptive immune system adapt?
-
Weng NP. Aging of the immune system: how much can the adaptive immune system adapt? Immunity. 2006;24:495-9.
-
(2006)
Immunity
, vol.24
, pp. 495-499
-
-
Weng, N.P.1
-
4
-
-
77957803871
-
Human NK cells display major phenotypic and functional changes over the life span
-
Le Garff-Tavernier M, Beziat V, Decocq J, Siguret V, Gandjbakhch F, Pautas E, et al. Human NK cells display major phenotypic and functional changes over the life span. Aging Cell. 2010;9:527-35.
-
(2010)
Aging Cell
, vol.9
, pp. 527-535
-
-
Garff-Tavernier, M.1
Beziat, V.2
Decocq, J.3
Siguret, V.4
Gandjbakhch, F.5
Pautas, E.6
-
5
-
-
0027381336
-
Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians
-
Sansoni P, Cossarizza A, Brianti V, Fagnoni F, Snelli G, Monti D, et al. Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood. 1993;82:2767-73.
-
(1993)
Blood
, vol.82
, pp. 2767-2773
-
-
Sansoni, P.1
Cossarizza, A.2
Brianti, V.3
Fagnoni, F.4
Snelli, G.5
Monti, D.6
-
7
-
-
0037397908
-
B cells in the aged: CD27, CD5, and CD40 expression
-
Colonna-Romano G, Bulati M, Aquino A, Scialabba G, Candore G, Lio D, et al. B cells in the aged: CD27, CD5, and CD40 expression. Mech Ageing Dev. 2003;124:389-93.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 389-393
-
-
Colonna-Romano, G.1
Bulati, M.2
Aquino, A.3
Scialabba, G.4
Candore, G.5
Lio, D.6
-
11
-
-
84940640942
-
Effects of aging on human leukocytes (part II): immunophenotyping of adaptive immune B and T cell subsets
-
Stervbo U, Bozzetti C, Baron U, Jurchott K, Meier S, Malzer JN, et al. Effects of aging on human leukocytes (part II): immunophenotyping of adaptive immune B and T cell subsets. Age (Dordr). 2015;37:93.
-
(2015)
Age (Dordr)
, vol.37
, pp. 93
-
-
Stervbo, U.1
Bozzetti, C.2
Baron, U.3
Jurchott, K.4
Meier, S.5
Malzer, J.N.6
-
12
-
-
84924925651
-
Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions
-
Lin Y, Damjanovic A, Metter EJ, Nguyen H, Truong T, Najarro K, et al. Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions. Clin Sci (Lond). 2015;128:367-77.
-
(2015)
Clin Sci (Lond)
, vol.128
, pp. 367-377
-
-
Lin, Y.1
Damjanovic, A.2
Metter, E.J.3
Nguyen, H.4
Truong, T.5
Najarro, K.6
-
14
-
-
33646397029
-
+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence
-
+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence. Clin Immunol. 2006;119:307-16.
-
(2006)
Clin Immunol
, vol.119
, pp. 307-316
-
-
Trzonkowski, P.1
Szmit, E.2
Mysliwska, J.3
Mysliwski, A.4
-
15
-
-
40849145398
-
T cell subset-specific susceptibility to aging
-
Czesnikiewicz-Guzik M, Lee WW, Cui D, Hiruma Y, Lamar DL, Yang ZZ, et al. T cell subset-specific susceptibility to aging. Clin Immunol. 2008;127:107-18.
-
(2008)
Clin Immunol
, vol.127
, pp. 107-118
-
-
Czesnikiewicz-Guzik, M.1
Lee, W.W.2
Cui, D.3
Hiruma, Y.4
Lamar, D.L.5
Yang, Z.Z.6
-
16
-
-
67649407892
-
CD28(-) T cells: their role in the age-associated decline of immune function
-
Weng NP, Akbar AN, Goronzy J. CD28(-) T cells: their role in the age-associated decline of immune function. Trends Immunol. 2009;30:306-12.
-
(2009)
Trends Immunol
, vol.30
, pp. 306-312
-
-
Weng, N.P.1
Akbar, A.N.2
Goronzy, J.3
-
17
-
-
84885402793
-
The effect of age on thymic function
-
Palmer DB. The effect of age on thymic function. Front Immunol. 2013;4:316.
-
(2013)
Front Immunol
, vol.4
, pp. 316
-
-
Palmer, D.B.1
-
18
-
-
84921634186
-
Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories
-
Nikolich-Zugich J. Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories. J Immunol. 2014;193:2622-9.
-
(2014)
J Immunol
, vol.193
, pp. 2622-2629
-
-
Nikolich-Zugich, J.1
-
21
-
-
33845625260
-
Ageing is associated with a decline in peripheral blood CD56bright NK cells
-
Chidrawar SM, Khan N, Chan YL, Nayak L, Moss PA. Ageing is associated with a decline in peripheral blood CD56bright NK cells. Immun Ageing. 2006;3:10.
-
(2006)
Immun Ageing
, vol.3
, pp. 10
-
-
Chidrawar, S.M.1
Khan, N.2
Chan, Y.L.3
Nayak, L.4
Moss, P.A.5
-
22
-
-
79959669679
-
Immunosenescence of human natural killer cells
-
Gayoso I, Sanchez-Correa B, Campos C, Alonso C, Pera A, Casado JG, et al. Immunosenescence of human natural killer cells. J Innate Immun. 2011;3:337-43.
-
(2011)
J Innate Immun
, vol.3
, pp. 337-343
-
-
Gayoso, I.1
Sanchez-Correa, B.2
Campos, C.3
Alonso, C.4
Pera, A.5
Casado, J.G.6
-
23
-
-
0037398104
-
Survival in a population sample is predicted by proportions of lymphocyte subsets
-
Huppert FA, Pinto EM, Morgan K, Brayne C. Survival in a population sample is predicted by proportions of lymphocyte subsets. Mech Ageing Dev. 2003;124:449-51.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 449-451
-
-
Huppert, F.A.1
Pinto, E.M.2
Morgan, K.3
Brayne, C.4
-
24
-
-
20544476197
-
An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans
-
Wikby A, Ferguson F, Forsey R, Thompson J, Strindhall J, Lofgren S, et al. An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans. J Gerontol A Biol Sci Med Sci. 2005;60:556-65.
-
(2005)
J Gerontol A Biol Sci Med Sci
, vol.60
, pp. 556-565
-
-
Wikby, A.1
Ferguson, F.2
Forsey, R.3
Thompson, J.4
Strindhall, J.5
Lofgren, S.6
-
25
-
-
84982269201
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B. 1995;57:289-300.
-
(1995)
J R Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
26
-
-
0034679070
-
Distinct categories of immunologic changes in frail elderly
-
Fahey JL, Schnelle JF, Boscardin J, Thomas JK, Gorre ME, Aziz N, et al. Distinct categories of immunologic changes in frail elderly. Mech Ageing Dev. 2000;115:1-20.
-
(2000)
Mech Ageing Dev
, vol.115
, pp. 1-20
-
-
Fahey, J.L.1
Schnelle, J.F.2
Boscardin, J.3
Thomas, J.K.4
Gorre, M.E.5
Aziz, N.6
-
28
-
-
84857416171
-
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
-
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mogling R, de Boer AB, et al. Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity. 2012;36:288-97.
-
(2012)
Immunity
, vol.36
, pp. 288-297
-
-
Braber, I.1
Mugwagwa, T.2
Vrisekoop, N.3
Westera, L.4
Mogling, R.5
Boer, A.B.6
-
29
-
-
84896501298
-
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans
-
Wertheimer AM, Bennett MS, Park B, Uhrlaub JL, Martinez C, Pulko V, et al. Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans. J Immunol. 2014;192:2143-55.
-
(2014)
J Immunol
, vol.192
, pp. 2143-2155
-
-
Wertheimer, A.M.1
Bennett, M.S.2
Park, B.3
Uhrlaub, J.L.4
Martinez, C.5
Pulko, V.6
-
31
-
-
15844364600
-
+ T cells throughout life, from newborns to centenarians: implications for T cell memory
-
+ T cells throughout life, from newborns to centenarians: implications for T cell memory. Mech Ageing Dev. 1996;86:173-95.
-
(1996)
Mech Ageing Dev
, vol.86
, pp. 173-195
-
-
Cossarizza, A.1
Ortolani, C.2
Paganelli, R.3
Barbieri, D.4
Monti, D.5
Sansoni, P.6
-
32
-
-
0029925555
-
Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age
-
Rea IM, Stewart M, Campbell P, Alexander HD, Crockard AD, Morris TC. Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age. Gerontology. 1996;42:69-78.
-
(1996)
Gerontology
, vol.42
, pp. 69-78
-
-
Rea, I.M.1
Stewart, M.2
Campbell, P.3
Alexander, H.D.4
Crockard, A.D.5
Morris, T.C.6
-
33
-
-
67249088372
-
+ T lymphocytes with naive or memory phenotype and their association with mortality in the elderly
-
+ T lymphocytes with naive or memory phenotype and their association with mortality in the elderly. Gerontology. 2009;55:314-21.
-
(2009)
Gerontology
, vol.55
, pp. 314-321
-
-
Provinciali, M.1
Moresi, R.2
Donnini, A.3
Lisa, R.M.4
-
34
-
-
0028839467
-
Immune parameters in a longitudinal study of a very old population of Swedish people: a comparison between survivors and nonsurvivors
-
Ferguson FG, Wikby A, Maxson P, Olsson J, Johansson B. Immune parameters in a longitudinal study of a very old population of Swedish people: a comparison between survivors and nonsurvivors. J Gerontol A Biol Sci Med Sci. 1995;50:B378-82.
-
(1995)
J Gerontol A Biol Sci Med Sci
, vol.50
, pp. B378-B382
-
-
Ferguson, F.G.1
Wikby, A.2
Maxson, P.3
Olsson, J.4
Johansson, B.5
-
35
-
-
0036644685
-
Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'
-
Pawelec G, Ouyang Q, Colonna-Romano G, Candore G, Lio D, Caruso C. Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'. Trends Immunol. 2002;23:330-2.
-
(2002)
Trends Immunol
, vol.23
, pp. 330-332
-
-
Pawelec, G.1
Ouyang, Q.2
Colonna-Romano, G.3
Candore, G.4
Lio, D.5
Caruso, C.6
-
36
-
-
0033026570
-
NK phenotypic markers and IL2 response in NK cells from elderly people
-
Borrego F, Alonso MC, Galiani MD, Carracedo J, Ramirez R, Ostos B, et al. NK phenotypic markers and IL2 response in NK cells from elderly people. Exp Gerontol. 1999;34:253-65.
-
(1999)
Exp Gerontol
, vol.34
, pp. 253-265
-
-
Borrego, F.1
Alonso, M.C.2
Galiani, M.D.3
Carracedo, J.4
Ramirez, R.5
Ostos, B.6
-
37
-
-
0037012021
-
Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study
-
Wikby A, Johansson B, Olsson J, Lofgren S, Nilsson BO, Ferguson F. Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Exp Gerontol. 2002;37:445-53.
-
(2002)
Exp Gerontol
, vol.37
, pp. 445-453
-
-
Wikby, A.1
Johansson, B.2
Olsson, J.3
Lofgren, S.4
Nilsson, B.O.5
Ferguson, F.6
-
38
-
-
84924266729
-
Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover
-
Westera L, van Hoeven V, Drylewicz J, Spierenburg G, van Velzen JF, De Boer RJ, et al. Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover. Aging Cell. 2015;14:219-27.
-
(2015)
Aging Cell
, vol.14
, pp. 219-227
-
-
Westera, L.1
Hoeven, V.2
Drylewicz, J.3
Spierenburg, G.4
Velzen, J.F.5
Boer, R.J.6
-
39
-
-
0036960253
-
IL-15 is a growth factor and an activator of CD8 memory T cells
-
Weng NP, Liu K, Catalfamo M, Li Y, Henkart PA. IL-15 is a growth factor and an activator of CD8 memory T cells. Ann N Y Acad Sci. 2002;975:46-56.
-
(2002)
Ann N Y Acad Sci
, vol.975
, pp. 46-56
-
-
Weng, N.P.1
Liu, K.2
Catalfamo, M.3
Li, Y.4
Henkart, P.A.5
-
40
-
-
0034029896
-
gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression
-
Patke CL, Shearer WT. gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression. J Allergy Clin Immunol. 2000;105:975-82.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 975-982
-
-
Patke, C.L.1
Shearer, W.T.2
-
41
-
-
83255176850
-
B cell immunosenescence: different features of naive and memory B cells in elderly
-
Buffa S, Bulati M, Pellicano M, Dunn-Walters DK, Wu YC, Candore G, et al. B cell immunosenescence: different features of naive and memory B cells in elderly. Biogerontology. 2011;12:473-83.
-
(2011)
Biogerontology
, vol.12
, pp. 473-483
-
-
Buffa, S.1
Bulati, M.2
Pellicano, M.3
Dunn-Walters, D.K.4
Wu, Y.C.5
Candore, G.6
-
43
-
-
84874209670
-
Advances in human B cell phenotypic profiling
-
Kaminski DA, Wei C, Qian Y, Rosenberg AF, Sanz I. Advances in human B cell phenotypic profiling. Front Immunol. 2012;3:302.
-
(2012)
Front Immunol
, vol.3
, pp. 302
-
-
Kaminski, D.A.1
Wei, C.2
Qian, Y.3
Rosenberg, A.F.4
Sanz, I.5
|