Ageing is associated with a decline in peripheral blood CD56bright NK cells

Immunity and Ageing

Volumn 3, Issue , 2006, Pages

  Chidrawar, Shivani M ^a   Khan, Naeem ^a   Chan, Y L Tracey ^a   Nayak, Laxman ^b   Moss, Paul A H ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b SELLY OAK HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; CYTOKINE;

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; CELLULAR IMMUNITY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; INNATE IMMUNITY; LYMPHOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; NATURAL KILLER CELL; PRIORITY JOURNAL; SENESCENCE;

EID: 33845625260     PISSN: 17424933     EISSN: None     Source Type: Journal    
DOI: 10.1186/1742-4933-3-10     Document Type: Article

References (26)

1. Robertson MJ, Ritz J: Biology and Clinical Relevance of Human Natural Killer Cell. Blood 1990, 76(12):2421-2438.
2. Papamichail M, Perez SO, Gritzapis AD, Baxevevanis CN: Natural Killer Lymphocytes: Biology, Development and Function. Cancer Immunology Immunotherapy 2004, 53:176-186.
3. Lanier LL, Corliss B, Phillips JH: Arousal and inhibition of human NK cells. Immunology Reviews 1997, 155:145-154.
4. Whiteside TL, Herberman RB: The role of natural killer cells in immune surveillance of cancer. Current Opinion in Immunology 1995, 7(5):704-710.
5. Miller GM, Andres ML, Gridley DS: NK cell depletion results in accelerated tumor growth and attenuates the antitumor effect of total body irradiation. International Journal of Oncology 2003, 6:1585-1592.
6. Kijima M, Saio M, Oyang GF, Suwa T, Miyauchi R, Kojima Y, Imai H, Nakagawa J. Nonaka K, Umemura N, Nishimura T, Takami T: Natural killer cells play a role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro. International Journal of Oncology 2005, 26(3):679-84.
7. Cerwenka A, Lanier LL: Natural Killer Cells, Viruses and Cancer. Nature Reviews Immunology 2001, 1:41-49.
8. Bukowski JF, Woda BA, Welsh RM: Pathogenesis of Murine Cytomegalovirus Infection in Natural Killer Depleted Mice. Journal of Virology 1984, 52(1):119-128.
9. Burkowski JF, Warner JF, Deenert D, Welsh RM: Adoptive transfer studies demonstrating the anti-viral effect of natural killer cells in vivo. Journal of Experimental Medicine 1985, 161(1):40-52.
10. Biron CA, Byron KS, Sullivan JL: Medical Intelligence. Severe herpesvirus infections in a adolescent girl without natural killer cells. New England Journal of Medicine 1989, 320(26):1731-1735.
11. Cooper MA, Fehniger TA, Caligiuri MA: The biology of human natural-killer subsets. Trends in immunology 2001, 22(11):633-640.
12. Castle SC: Clinical relevance of age-related immune dysfunction. Clinical Infectious Diseases 2000, 31:578-585.
13. Ramos-Casals M, Garcia-Carrasco M, Brito MP, Lopez-Soto A, Font J: Autoimmunity and geriatrics: clinical significance of autoimmune manifestations in the elderly. Lupus 2003, 12:341-355.
14. Denduluri N, Ershler WB: Ageing biology and cancer. Seminars in Oncology 2004, 31:137-148.
15. Simonsen L, Reichert TA, Viboud C, Blackwelder WC, Taylor RJ, Miller MA: Impact of influenza vaccination on seasonal mortality in the US elderly population. Archives of Internal Medicine 2005, 165:265-272.
16. Remarque E, Pawelec P: T cell immunosensescence and its clinical relevance in man. Reviews in Clinical Gerontology 1998, 8:5-14.
17. Facchini A, Mariani E, Mariani AR, Papa S, Vitale M, Manzoli FA: Increased number of circulating Leul 1 +(CD 16) large granular lymphocytes and decreased NK activity during human ageing. Clinical Experimental Immunology 1987, 68(2):340-347.
18. Sansoni P, Cossarizza A, Brianti V, Fagoni F, Snelli G, Monti D, Marcarto A, Passeri G, Ortolani C, Ford E: Lymphocyte subsets and natural killer cell activity in health people and centarians. Blood 1993, 82:2762773.
19. Krishnaraj R: Senescence and cytokines modulate the NK cell expression. Mechanisms of ageing and development 1997, 96(13):89-101.
20. Borrego F, Alonso MC, Galiani MD, Carracedo J, Ramirez R, Ostos B, Pena J, Solana R: NK Phenotypic markers and IL2 response in NK cells from elderly people. Experimental Gerontology 1999, 34:253-265.
21. Lanier LL, Le AM, Civin CI, Loken MR, Phillips JH: The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. Journal of Immunology 1989, 136:4480-4486.
22. Cooper MA, Fehniger TA, Turner SC, Kenneth S, Chen S, Bobak A, Shaheri TG, Carson WE, Caligiuri MA: Human natural killer cells; a unique innate immunoregulatory role for the CD56bright subset. Blood 2001, 97(10):3146-3151.
23. Nagler A: Comparative studies of human FcRIII- positive and -negative natural killer cells. Journal of Immunology 1989, 143:3183-3191.
24. Vitale M, Della Chiesa M, Carlomagno S, Romagnani C, Thiel A, Moretta L, Moretta A: The small subset of CD56brightCD16-natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells. European Journal of Immunology 2004, 34(6):1715-1722.
25. bright NK Cells are Enriched at Inflammatory Sites and Can Engage with Monocytes in a Reciprocal Programme of Activation. The Journal of Immunology 2004, 173:6418-6426.
26. Fehniger TA, Cooper MA, Nuovo GJ, Cella M, Faccetti F, Colonna M, Caligiuri MA: CD56bright natural killer cells are present in human lymph nodes and are activated by T cell derived IL-2: a potential new link between adaptive and innate immunity. Blood 2003, 101(8):3052-7.