Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover

Aging Cell

Volumn 14, Issue 2, 2015, Pages 219-227

  Westera, Liset ^a   van Hoeven, Vera ^a   Drylewicz, Julia ^a,b   Spierenburg, Gerrit ^a   van Velzen, Jeroen F ^a   de Boer, Rob J ^b   Tesselaar, Kiki ^a   Borghans, José A M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Healthy aging; Homeostasis; Lymphocyte turnover; Mathematical modeling; Stable isotope labeling; Thymus involution

Indexed keywords

DEUTERIUM; GENOMIC DNA; WATER;

AGED; ARTICLE; B LYMPHOCYTE; BODY WATER; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL AGING; CELL ISOLATION; CELL SELECTION; CELL TURNOVER; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTOPOIESIS; MALE; MASS FRAGMENTOGRAPHY; MEMORY CELL; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMUS; TURNOVER TIME; VERY ELDERLY; AGING; CHEMISTRY; CYTOLOGY; HOMEOSTASIS; IMMUNOLOGY; PHYSIOLOGY; YOUNG ADULT;

AGED; AGING; DEUTERIUM; FEMALE; FLOW CYTOMETRY; HOMEOSTASIS; HUMANS; MALE; T-LYMPHOCYTES; WATER; YOUNG ADULT;

EID: 84924266729     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12311     Document Type: Article

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