B cells in the aged: CD27, CD5, and CD40 expression

Mechanisms of Ageing and Development

Volumn 124, Issue 4, 2003, Pages 389-393

  Colonna Romano, Giuseppina ^a   Bulati, Matteo ^a   Aquino, Alessandra ^a   Scialabba, Giuseppe ^a   Candore, Giuseppina ^a   Lio, Domenico ^a   Motta, Massimo ^b   Malaguarnera, Mariano ^b   Caruso, Calogero ^c  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c NONE

Author keywords

CD27; CD40; CD5

Indexed keywords

AUTOANTIBODY; CD27 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD5 ANTIGEN;

ADULT; AGED; AGING; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN BINDING; ANTIGEN EXPRESSION; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CELLULAR IMMUNITY; CONFERENCE PAPER; GERONTOLOGY; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; NATURAL KILLER CELL; NORMAL HUMAN; PLASMA CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0037397908     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(03)00013-7     Document Type: Conference Paper

References (25)

1. Agematsu K., Hokibara S., Nagumo H., Komiyama A. CD27: a memory B-cell marker. Immunol. Today. 21:2000;204-206.
2. Baumgartner L. Qualitative changes in antisera associated with age. J. Immunol. 27:1934;407-416.
3. Blanca I.R., Bere E.W., Young H.A., Ortaldo J.R. Human B cell activation by autologous NK cells is regulated by CD40-CD40 ligand interaction: role of memory D cells and CD5+ B cells. J. Immunol. 167:2001;6132-6139.
4. Candore G., Di Lorenzo G., Mansueto P., Melluso M., Fradà G., Li Vecchi M., Esposito Pellitteri M., Di Salvo A., Caruso C. Prevalence of organ-specific and non-organ-specific autoantibodies in healthy centenarians. Mech. Aging Dev. 94:1997;183-190.
5. Colonna Romano G., Potestio M., Aquino A., Candore G., Lio D., Caruso C. Gamma/delta T lymphocytes are affected in the elderly. Exp. Gerontol. 37:2002;205-211.
6. Colonna Romano G., Cossarizza A., Aquino A., Scialabba G., Bulati M., Lio D., Candore G., Di Lorenzo G., Caruso C. Age- and sex-related values of lymphocyte subsets in subjects from North and South Italy. Arch. Gerontol. Geriatrics. 8:2002b;99-107.
7. Cossarizza A., Ortolani C., Paganelli R., Barbieri D., Monti D., Sansoni P., Fagiolo U., Castellani G., Bersani F., Londei M., Franceschi C. CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory. Mech. Aging Dev. 86:1996;173-195.
8. Cossarizza A., Ortolani C., Monti D., Franceschi C. Cytometric analysis of immunosenescence. Cytometry. 27:1997;297-313.
9. Effros R.B. Ageing and immune system. Novartis Found Symp. 235:2001;130-149.
10. Fagnoni F.P., Vescovili R., Passeri G., Bologna G., Pedrazzoni M., Lavagetto G., Casti A., Franceschi C., Passeri M., Sansoni P. Shortage of circulating naive CD8+ T cells provides new insights on immunodeficiency in aging. Blood. 95:2000;2860-2868.
11. Franceschi C., Monti D., Sansoni P., Cossarizza A. The immunology of exceptional individuals: the lesson of centenarians. Immunol. Today. 16:1995;12-16.
12. Franceschi C., BonafÌ M., Valensin S., Olivieri F., De Luca M., Ottavini E., De Benedictis G. Inflamm-aging: an evolutionary perspective of immunosenescence. Ann. NY Acad. Sci. 908:2000;244-254.
13. Grewal I.S., Flavell R.A. CD40 and CD154 in cell mediated immunity. Ann. Rev. Immunol. 16:1998;111-135.
14. Globerson A., Effros R.B. Ageing of lymphocytes and lymphocytes in the aged. Immunol. Today. 21:2000;515-521.
15. Le Maoult J., Szabo P., Weksler M.E. Effect of age on humoral immunity, selection of the B-cell repertoire and b-cell development. Immunol. Rev. 160:1997;115-126.
16. Listì, F., Modica, M.A., Botindari, C., Balistreri, C.R., Lio, D., Colonna Romano, G., Di Lorenzo, G., Candore, G., Franceschi, C., Caruso, C., 2002. Third International Conference on Basic Biology and Clinical Impact of Immunosenescence, Palermo, April 10-14, 2002.
17. Olsson J., Wikby A., Johansson B., Lofgren S., Nilsson B.O., Ferguson F.G. Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study. Mech. Aging Dev. 121:2000;187-201.
18. Pawelec G., Barnett Y., Forsey R., Frasca D., Globerson A., McLeod J., Caruso C., Franceschi C., Fulop T., Gupta S., Mariani E., Mocchegiani E., Solana R. T cells and aging, january 2002 update. Front Biosci. 7:2002;D1056-1183.
19. Potestio M., Pawelec G., Di Lorenzo G., Candore G., D'Anna C., Gervasi F., Lio D., Tranchida G., Caruso C., Colonna-Romano G. Age-related changes in the expression of CD95 (APO1/FAS) on blood lymphocytes. Exp. Gerontol. 34:1999;659-673.
20. Rodriguez M.A., Blanca I., Baroja M.L., Arama S., Leon-Ponte M., Abadi I., Bianco N.E. Helper activity by human large granular lymphocytes in in vitro immunoglobulin synthesis. J. Clin. Immunol. 7:1987;356-364.
21. Solana R., Mariani E. NK and NK/T cells in human senescence. Vaccine. 18:2000;1613-1620.
22. Song H., Price P.W., Cerny J. Age-related changes in antibody repertoire: contribution from T cells. Immunol. Rev. 160:1997;55-62.
23. Weksler M.E. Changes in B cell repertoire with age. Vaccine. 18:2000;1624-1628.
24. Weksler M.E., Szabo P. The effect of age on the B-cell repertoire. J. Clin. Immunol. 20:2000;240-249.
25. Wikby A., Maxson P., Olsson J., Johansson B., Ferguson F.G. Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO immune study. Mech. Aging Dev. 102:1998;187-198.