A general method to improve fluorophores for live-cell and single-molecule microscopy

Nature Methods

Volumn 12, Issue 3, 2015, Pages 244-250

  Grimm, Jonathan B ^a   English, Brian P ^a   Chen, Jiji ^a   Slaughter, Joel P ^a   Zhang, Zhengjian ^a   Revyakin, Andrey ^a,b   Patel, Ronak ^a   Macklin, John J ^a   Normanno, Davide ^a,c   Singer, Robert H ^a,d   Lionnet, Timothée ^a   Lavis, Luke D ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c INSTITUT CURIE   (France)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CARBOXYFLUORESCEIN; ACRIDINE DERIVATIVE; AZETIDINE; AZIRIDINE DERIVATIVE; COUMARIN DERIVATIVE; DNA BINDING PROTEIN; FLUORESCENT DYE; NAPHTHALIMIDE DERIVATIVE; RHODAMINE 110; TETRAALKYLRHODAMINE DYE; TETRAMETHYLRHODAMINE; UNCLASSIFIED DRUG; AZETIDINE DERIVATIVE; COUMARIN; FLUORESCEIN; RHODAMINE;

ALKYLATION; AQUEOUS SOLUTION; ARTICLE; BRIGHTNESS; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHROMATIN STRUCTURE; ELECTRON TRANSPORT; FEMALE; FLUORESCENCE MICROSCOPY; HELA CELL LINE; HUMAN; HUMAN CELL; MOLECULAR MODEL; PHOTON; PRIORITY JOURNAL; QUANTUM YIELD; SPECTRUM; TRANSIENT TRANSFECTION; U2OS CELL LINE; ULTRAVIOLET RADIATION; CHEMISTRY; MOLECULAR IMAGING; PROCEDURES; QUANTUM THEORY; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ULTRAVIOLET MICROSCOPY; ULTRAVIOLET SPECTROPHOTOMETRY;

AZETIDINES; CHEMISTRY TECHNIQUES, SYNTHETIC; COUMARINS; FLUORESCEIN; FLUORESCENT DYES; HELA CELLS; HUMANS; MICROSCOPY, ULTRAVIOLET; MODELS, MOLECULAR; MOLECULAR IMAGING; QUANTUM THEORY; RHODAMINES; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84923803017     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3256     Document Type: Article

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