메뉴 건너뛰기




Volumn 17, Issue 1, 2016, Pages

Genetic analysis of variation in lifespan using a multiparental advanced intercross Drosophila mapping population

Author keywords

Aging; Complex traits; Lifespan; Multiparental populations; QTL mapping; RNAseq

Indexed keywords

RNA;

EID: 84980385897     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/s12863-016-0419-9     Document Type: Article
Times cited : (20)

References (86)
  • 1
    • 84943634474 scopus 로고    scopus 로고
    • United States life tables
    • Hyattsville, MD: National Center for Health Statistics
    • Arias E. United States life tables, 2011. In: National vital statistics reports. vol. 64. Hyattsville, MD: National Center for Health Statistics; 2015.
    • (2015) National vital statistics reports , vol.64
    • Arias, E.1
  • 2
    • 84866183226 scopus 로고    scopus 로고
    • Ageing as a risk factor for disease
    • Niccoli T, Partridge L. Ageing as a risk factor for disease. Curr Biol. 2012;22(17):R741-752.
    • (2012) Curr Biol , vol.22 , Issue.17 , pp. R741-752
    • Niccoli, T.1    Partridge, L.2
  • 4
    • 0030062815 scopus 로고    scopus 로고
    • The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900
    • Herskind AM, McGue M, Holm NV, Sorensen TI, Harvald B, Vaupel JW. The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900. Hum Genet. 1996;97(3):319-23.
    • (1996) Hum Genet , vol.97 , Issue.3 , pp. 319-323
    • Herskind, A.M.1    McGue, M.2    Holm, N.V.3    Sorensen, T.I.4    Harvald, B.5    Vaupel, J.W.6
  • 5
    • 0027482067 scopus 로고
    • Longevity is moderately heritable in a sample of Danish twins born 1870-1880
    • McGue M, Vaupel JW, Holm N, Harvald B. Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J Gerontol. 1993;48(6):B237-244.
    • (1993) J Gerontol , vol.48 , Issue.6 , pp. B237-244
    • McGue, M.1    Vaupel, J.W.2    Holm, N.3    Harvald, B.4
  • 6
    • 84904741764 scopus 로고    scopus 로고
    • Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
    • Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Hum Mol Genet. 2014;23(16):4420-32.
    • (2014) Hum Mol Genet , vol.23 , Issue.16 , pp. 4420-4432
    • Deelen, J.1    Beekman, M.2    Uh, H.W.3    Broer, L.4    Ayers, K.L.5    Tan, Q.6    Kamatani, Y.7    Bennet, A.M.8    Tamm, R.9    Trompet, S.10
  • 10
    • 53749092728 scopus 로고    scopus 로고
    • Power for genetic association study of human longevity using the case-control design
    • Tan Q, Zhao JH, Zhang D, Kruse TA, Christensen K. Power for genetic association study of human longevity using the case-control design. Am J Epidemiol. 2008;168(8):890-6.
    • (2008) Am J Epidemiol , vol.168 , Issue.8 , pp. 890-896
    • Tan, Q.1    Zhao, J.H.2    Zhang, D.3    Kruse, T.A.4    Christensen, K.5
  • 11
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard JK. Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet. 2001;69(1):124-37.
    • (2001) Am J Hum Genet , vol.69 , Issue.1 , pp. 124-137
    • Pritchard, J.K.1
  • 12
    • 67149095078 scopus 로고    scopus 로고
    • Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip
    • Spencer CC, Su Z, Donnelly P, Marchini J. Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet. 2009;5(5), e1000477.
    • (2009) PLoS Genet , vol.5 , Issue.5
    • Spencer, C.C.1    Su, Z.2    Donnelly, P.3    Marchini, J.4
  • 13
    • 84874770275 scopus 로고    scopus 로고
    • Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect
    • Thornton KR, Foran AJ, Long AD. Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect. PLoS Genet. 2013;9(2), e1003258.
    • (2013) PLoS Genet , vol.9 , Issue.2
    • Thornton, K.R.1    Foran, A.J.2    Long, A.D.3
  • 14
    • 84925852614 scopus 로고    scopus 로고
    • Promoting health and longevity through diet: from model organisms to humans
    • Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 2015;161(1):106-18.
    • (2015) Cell , vol.161 , Issue.1 , pp. 106-118
    • Fontana, L.1    Partridge, L.2
  • 15
    • 34547223572 scopus 로고    scopus 로고
    • Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial
    • Fontana L, Villareal DT, Weiss EP, Racette SB, Steger-May K, Klein S, Holloszy JO, Washington University School of Medicine CG. Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab. 2007;293(1):E197-202.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , Issue.1 , pp. E197-202
    • Fontana, L.1    Villareal, D.T.2    Weiss, E.P.3    Racette, S.B.4    Steger-May, K.5    Klein, S.6    Holloszy, J.O.7
  • 17
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993;366(6454):461-4.
    • (1993) Nature , vol.366 , Issue.6454 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 18
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science. 1997;277(5328):942-6.
    • (1997) Science , vol.277 , Issue.5328 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 23
    • 69249113100 scopus 로고    scopus 로고
    • Dissecting the genetics of longevity in Drosophila melanogaster
    • Paaby AB, Schmidt PS. Dissecting the genetics of longevity in Drosophila melanogaster. Fly (Austin). 2009;3(1):29-38.
    • (2009) Fly (Austin) , vol.3 , Issue.1 , pp. 29-38
    • Paaby, A.B.1    Schmidt, P.S.2
  • 24
    • 0036132290 scopus 로고    scopus 로고
    • The nature of quantitative genetic variation for Drosophila longevity
    • Mackay TF. The nature of quantitative genetic variation for Drosophila longevity. Mech Ageing Dev. 2002;123(2-3):95-104.
    • (2002) Mech Ageing Dev , vol.123 , Issue.2-3 , pp. 95-104
    • Mackay, T.F.1
  • 27
    • 84863880314 scopus 로고    scopus 로고
    • Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits
    • King EG, Macdonald SJ, Long AD. Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits. Genetics. 2012;191(3):935-49.
    • (2012) Genetics , vol.191 , Issue.3 , pp. 935-949
    • King, E.G.1    Macdonald, S.J.2    Long, A.D.3
  • 29
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill GA, Doerge RW. Empirical threshold values for quantitative trait mapping. Genetics. 1994;138(3):963-71.
    • (1994) Genetics , vol.138 , Issue.3 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 30
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 2013;14(4):R36.
    • (2013) Genome Biol , vol.14 , Issue.4 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 31
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics. 2009;25(9):1105-11.
    • (2009) Bioinformatics , vol.25 , Issue.9 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 32
    • 79952709611 scopus 로고    scopus 로고
    • Improving RNA-Seq expression estimates by correcting for fragment bias
    • Roberts A, Trapnell C, Donaghey J, Rinn JL, Pachter L. Improving RNA-Seq expression estimates by correcting for fragment bias. Genome Biol. 2011;12(3):R22.
    • (2011) Genome Biol , vol.12 , Issue.3 , pp. R22
    • Roberts, A.1    Trapnell, C.2    Donaghey, J.3    Rinn, J.L.4    Pachter, L.5
  • 34
  • 37
    • 80053641483 scopus 로고    scopus 로고
    • Increased transsulfuration mediates longevity and dietary restriction in Drosophila
    • Kabil H, Kabil O, Banerjee R, Harshman LG, Pletcher SD. Increased transsulfuration mediates longevity and dietary restriction in Drosophila. Proc Natl Acad Sci U S A. 2011;108(40):16831-6.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.40 , pp. 16831-16836
    • Kabil, H.1    Kabil, O.2    Banerjee, R.3    Harshman, L.G.4    Pletcher, S.D.5
  • 38
    • 0036132117 scopus 로고    scopus 로고
    • Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila
    • Curtsinger JW, Khazaeli AA. Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila. Mech Ageing Dev. 2002;123(2-3):81-93.
    • (2002) Mech Ageing Dev , vol.123 , Issue.2-3 , pp. 81-93
    • Curtsinger, J.W.1    Khazaeli, A.A.2
  • 40
    • 5144234956 scopus 로고    scopus 로고
    • Quantitative trait loci affecting life span in replicated populations of Drosophila melanogaster. I. Composite interval mapping
    • Forbes SN, Valenzuela RK, Keim P, Service PM. Quantitative trait loci affecting life span in replicated populations of Drosophila melanogaster. I. Composite interval mapping. Genetics. 2004;168(1):301-11.
    • (2004) Genetics , vol.168 , Issue.1 , pp. 301-311
    • Forbes, S.N.1    Valenzuela, R.K.2    Keim, P.3    Service, P.M.4
  • 41
    • 1542328246 scopus 로고    scopus 로고
    • Quantitative trait loci affecting natural variation in Drosophila longevity
    • Geiger-Thornsberry GL, Mackay TF. Quantitative trait loci affecting natural variation in Drosophila longevity. Mech Ageing Dev. 2004;125(3):179-89.
    • (2004) Mech Ageing Dev , vol.125 , Issue.3 , pp. 179-189
    • Geiger-Thornsberry, G.L.1    Mackay, T.F.2
  • 43
    • 0033870603 scopus 로고    scopus 로고
    • Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density
    • Leips J, Mackay TF. Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density. Genetics. 2000;155(4):1773-88.
    • (2000) Genetics , vol.155 , Issue.4 , pp. 1773-1788
    • Leips, J.1    Mackay, T.F.2
  • 44
    • 0036791332 scopus 로고    scopus 로고
    • The complex genetic architecture of Drosophila life span
    • Leips J, Mackay TF. The complex genetic architecture of Drosophila life span. Exp Aging Res. 2002;28(4):361-90.
    • (2002) Exp Aging Res , vol.28 , Issue.4 , pp. 361-390
    • Leips, J.1    Mackay, T.F.2
  • 45
    • 22144454658 scopus 로고    scopus 로고
    • Survival analysis of life span quantitative trait loci in Drosophila melanogaster
    • Nuzhdin SV, Khazaeli AA, Curtsinger JW. Survival analysis of life span quantitative trait loci in Drosophila melanogaster. Genetics. 2005;170(2):719-31.
    • (2005) Genetics , vol.170 , Issue.2 , pp. 719-731
    • Nuzhdin, S.V.1    Khazaeli, A.A.2    Curtsinger, J.W.3
  • 46
    • 0037004596 scopus 로고    scopus 로고
    • Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes
    • Reiwitch SG, Nuzhdin SV. Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes. Genet Res. 2002;80(3):225-30.
    • (2002) Genet Res , vol.80 , Issue.3 , pp. 225-230
    • Reiwitch, S.G.1    Nuzhdin, S.V.2
  • 47
    • 0033979887 scopus 로고    scopus 로고
    • Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster
    • Vieira C, Pasyukova EG, Zeng ZB, Hackett JB, Lyman RF, Mackay TF. Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster. Genetics. 2000;154(1):213-27.
    • (2000) Genetics , vol.154 , Issue.1 , pp. 213-227
    • Vieira, C.1    Pasyukova, E.G.2    Zeng, Z.B.3    Hackett, J.B.4    Lyman, R.F.5    Mackay, T.F.6
  • 48
    • 13844286030 scopus 로고    scopus 로고
    • Environment-dependent survival of Drosophila melanogaster: a quantitative genetic analysis
    • Wang MH, Lazebny O, Harshman LG, Nuzhdin SV. Environment-dependent survival of Drosophila melanogaster: a quantitative genetic analysis. Aging Cell. 2004;3(3):133-40.
    • (2004) Aging Cell , vol.3 , Issue.3 , pp. 133-140
    • Wang, M.H.1    Lazebny, O.2    Harshman, L.G.3    Nuzhdin, S.V.4
  • 49
    • 33746458528 scopus 로고    scopus 로고
    • High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster
    • Wilson RH, Morgan TJ, Mackay TF. High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. Genetics. 2006;173(3):1455-63.
    • (2006) Genetics , vol.173 , Issue.3 , pp. 1455-1463
    • Wilson, R.H.1    Morgan, T.J.2    Mackay, T.F.3
  • 50
    • 84892492038 scopus 로고    scopus 로고
    • Genome-wide association study of extreme longevity in Drosophila melanogaster
    • Burke MK, King EG, Shahrestani P, Rose MR, Long AD. Genome-wide association study of extreme longevity in Drosophila melanogaster. Genome Biol Evol. 2014;6(1):1-11.
    • (2014) Genome Biol Evol , vol.6 , Issue.1 , pp. 1-11
    • Burke, M.K.1    King, E.G.2    Shahrestani, P.3    Rose, M.R.4    Long, A.D.5
  • 51
    • 84927509365 scopus 로고    scopus 로고
    • Dissecting complex traits using the Drosophila Synthetic Population Resource
    • Long AD, Macdonald SJ, King EG. Dissecting complex traits using the Drosophila Synthetic Population Resource. Trends Genet. 2014;30(11):488-95.
    • (2014) Trends Genet , vol.30 , Issue.11 , pp. 488-495
    • Long, A.D.1    Macdonald, S.J.2    King, E.G.3
  • 52
    • 84937881471 scopus 로고    scopus 로고
    • Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus
    • Lu HL, Wang JB, Brown MA, Euerle C, St Leger RJ. Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus. Sci Rep. 2015;5:12350.
    • (2015) Sci Rep , vol.5 , pp. 12350
    • Lu, H.L.1    Wang, J.B.2    Brown, M.A.3    Euerle, C.4    St Leger, R.J.5
  • 53
    • 47249142778 scopus 로고    scopus 로고
    • Revealing the architecture of gene regulation: the promise of eQTL studies
    • Gilad Y, Rifkin SA, Pritchard JK. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008;24(8):408-15.
    • (2008) Trends Genet , vol.24 , Issue.8 , pp. 408-415
    • Gilad, Y.1    Rifkin, S.A.2    Pritchard, J.K.3
  • 56
    • 84946735654 scopus 로고    scopus 로고
    • Gene Ontology Consortium: going forward
    • Consortium GO. Gene Ontology Consortium: going forward. Nucleic Acids Res. 2015;43(Database issue):D1049-1056.
    • (2015) Nucleic Acids Res , vol.43 , Issue.DATABASE ISSUE , pp. D1049-1056
    • Consortium, G.O.1
  • 58
    • 33846858644 scopus 로고    scopus 로고
    • Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping
    • Lai CQ, Parnell LD, Lyman RF, Ordovas JM, Mackay TF. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev. 2007;128(3):237-49.
    • (2007) Mech Ageing Dev , vol.128 , Issue.3 , pp. 237-249
    • Lai, C.Q.1    Parnell, L.D.2    Lyman, R.F.3    Ordovas, J.M.4    Mackay, T.F.5
  • 61
    • 34547631266 scopus 로고    scopus 로고
    • Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster
    • Zhan M, Yamaza H, Sun Y, Sinclair J, Li H, Zou S. Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster. Genome Res. 2007;17(8):1236-43.
    • (2007) Genome Res , vol.17 , Issue.8 , pp. 1236-1243
    • Zhan, M.1    Yamaza, H.2    Sun, Y.3    Sinclair, J.4    Li, H.5    Zou, S.6
  • 63
    • 84948174122 scopus 로고    scopus 로고
    • Efficient Test and Visualization of Multi-Set Intersections
    • Wang M, Zhao Y, Zhang B. Efficient Test and Visualization of Multi-Set Intersections. Sci Rep. 2015;5:16923.
    • (2015) Sci Rep , vol.5 , pp. 16923
    • Wang, M.1    Zhao, Y.2    Zhang, B.3
  • 65
    • 34547440528 scopus 로고    scopus 로고
    • Increased internal and external bacterial load during Drosophila aging without life-span trade-off
    • Ren C, Webster P, Finkel SE, Tower J. Increased internal and external bacterial load during Drosophila aging without life-span trade-off. Cell Metab. 2007;6(2):144-52.
    • (2007) Cell Metab , vol.6 , Issue.2 , pp. 144-152
    • Ren, C.1    Webster, P.2    Finkel, S.E.3    Tower, J.4
  • 66
    • 80053424095 scopus 로고    scopus 로고
    • The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
    • Wang JW, Brent JR, Tomlinson A, Shneider NA, McCabe BD. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011;121(10):4118-26.
    • (2011) J Clin Invest , vol.121 , Issue.10 , pp. 4118-4126
    • Wang, J.W.1    Brent, J.R.2    Tomlinson, A.3    Shneider, N.A.4    McCabe, B.D.5
  • 67
    • 23844531242 scopus 로고    scopus 로고
    • The hangover gene defines a stress pathway required for ethanol tolerance development
    • Scholz H, Franz M, Heberlein U. The hangover gene defines a stress pathway required for ethanol tolerance development. Nature. 2005;436(7052):845-7.
    • (2005) Nature , vol.436 , Issue.7052 , pp. 845-847
    • Scholz, H.1    Franz, M.2    Heberlein, U.3
  • 68
    • 0141865686 scopus 로고    scopus 로고
    • Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus
    • Symphorien S, Woodruff RC. Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus. J Gerontol A Biol Sci Med Sci. 2003;58(9):B782-787.
    • (2003) J Gerontol A Biol Sci Med Sci , vol.58 , Issue.9 , pp. B782-787
    • Symphorien, S.1    Woodruff, R.C.2
  • 69
    • 0032582489 scopus 로고    scopus 로고
    • Extended life-span and stress resistance in the Drosophila mutant methuselah
    • Lin YJ, Seroude L, Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science. 1998;282(5390):943-6.
    • (1998) Science , vol.282 , Issue.5390 , pp. 943-946
    • Lin, Y.J.1    Seroude, L.2    Benzer, S.3
  • 70
    • 84908432541 scopus 로고    scopus 로고
    • Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells
    • Homem CC, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA. Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 2014;158(4):874-88.
    • (2014) Cell , vol.158 , Issue.4 , pp. 874-888
    • Homem, C.C.1    Steinmann, V.2    Burkard, T.R.3    Jais, A.4    Esterbauer, H.5    Knoblich, J.A.6
  • 71
    • 34250728186 scopus 로고    scopus 로고
    • Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
    • Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD. Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. Genetics. 2007;176(2):1283-97.
    • (2007) Genetics , vol.176 , Issue.2 , pp. 1283-1297
    • Simonsen, A.1    Cumming, R.C.2    Lindmo, K.3    Galaviz, V.4    Cheng, S.5    Rusten, T.E.6    Finley, K.D.7
  • 74
    • 35448970692 scopus 로고    scopus 로고
    • Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes
    • Li A, Xie Z, Dong Y, McKay KM, McKee ML, Tanzi RE. Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet. 2007;16(21):2626-39.
    • (2007) Hum Mol Genet , vol.16 , Issue.21 , pp. 2626-2639
    • Li, A.1    Xie, Z.2    Dong, Y.3    McKay, K.M.4    McKee, M.L.5    Tanzi, R.E.6
  • 75
    • 57749094923 scopus 로고    scopus 로고
    • Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster
    • Legan SK, Rebrin I, Mockett RJ, Radyuk SN, Klichko VI, Sohal RS, Orr WC. Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster. J Biol Chem. 2008;283(47):32492-9.
    • (2008) J Biol Chem , vol.283 , Issue.47 , pp. 32492-32499
    • Legan, S.K.1    Rebrin, I.2    Mockett, R.J.3    Radyuk, S.N.4    Klichko, V.I.5    Sohal, R.S.6    Orr, W.C.7
  • 76
    • 0034622645 scopus 로고    scopus 로고
    • Disruption of the microsomal glutathione S-transferase-like gene reduces life span of Drosophila melanogaster
    • Toba G, Aigaki T. Disruption of the microsomal glutathione S-transferase-like gene reduces life span of Drosophila melanogaster. Gene. 2000;253(2):179-87.
    • (2000) Gene , vol.253 , Issue.2 , pp. 179-187
    • Toba, G.1    Aigaki, T.2
  • 77
    • 79959380753 scopus 로고    scopus 로고
    • Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo
    • Liu J, Wu Q, He D, Ma T, Du L, Dui W, Guo X, Jiao R. Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo. J Genet Genomics. 2011;38(6):225-34.
    • (2011) J Genet Genomics , vol.38 , Issue.6 , pp. 225-234
    • Liu, J.1    Wu, Q.2    He, D.3    Ma, T.4    Du, L.5    Dui, W.6    Guo, X.7    Jiao, R.8
  • 78
    • 84898663884 scopus 로고    scopus 로고
    • Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function
    • Cuartero S, Fresan U, Reina O, Planet E, Espinas ML. Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function. EMBO J. 2014;33(6):637-47.
    • (2014) EMBO J , vol.33 , Issue.6 , pp. 637-647
    • Cuartero, S.1    Fresan, U.2    Reina, O.3    Planet, E.4    Espinas, M.L.5
  • 79
    • 0034919060 scopus 로고    scopus 로고
    • High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span
    • Landis G, Bhole D, Lu L, Tower J. High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span. Genetics. 2001;158(3):1167-76.
    • (2001) Genetics , vol.158 , Issue.3 , pp. 1167-1176
    • Landis, G.1    Bhole, D.2    Lu, L.3    Tower, J.4
  • 80
    • 84877095701 scopus 로고    scopus 로고
    • The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia
    • Petersen AJ, Katzenberger RJ, Wassarman DA. The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia. Genetics. 2013;194(1):133-42.
    • (2013) Genetics , vol.194 , Issue.1 , pp. 133-142
    • Petersen, A.J.1    Katzenberger, R.J.2    Wassarman, D.A.3
  • 81
    • 84941317162 scopus 로고    scopus 로고
    • Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species
    • Yu S, Jang Y, Paik D, Lee E, Park JJ. Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species. Biochem Biophys Res Commun. 2015;465(4):845-50.
    • (2015) Biochem Biophys Res Commun , vol.465 , Issue.4 , pp. 845-850
    • Yu, S.1    Jang, Y.2    Paik, D.3    Lee, E.4    Park, J.J.5
  • 82
    • 79251471784 scopus 로고    scopus 로고
    • Genetics and genomics of human ageing
    • Wheeler HE, Kim SK. Genetics and genomics of human ageing. Philos T R Soc B. 2011;366(1561):43-50.
    • (2011) Philos T R Soc B , vol.366 , Issue.1561 , pp. 43-50
    • Wheeler, H.E.1    Kim, S.K.2
  • 83
    • 48149112576 scopus 로고    scopus 로고
    • Diet and aging
    • Piper MD, Bartke A. Diet and aging. Cell Metab. 2008;8(2):99-104.
    • (2008) Cell Metab , vol.8 , Issue.2 , pp. 99-104
    • Piper, M.D.1    Bartke, A.2
  • 84
    • 0042422245 scopus 로고    scopus 로고
    • Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background
    • Spencer CC, Howell CE, Wright AR, Promislow DE. Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background. Aging Cell. 2003;2(2):123-30.
    • (2003) Aging Cell , vol.2 , Issue.2 , pp. 123-130
    • Spencer, C.C.1    Howell, C.E.2    Wright, A.R.3    Promislow, D.E.4
  • 85
    • 84901645732 scopus 로고    scopus 로고
    • GxGxE for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity
    • Zhu CT, Ingelmo P, Rand DM. GxGxE for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity. PLoS Genet. 2014;10(5), e1004354.
    • (2014) PLoS Genet , vol.10 , Issue.5
    • Zhu, C.T.1    Ingelmo, P.2    Rand, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.