-
1
-
-
84943634474
-
United States life tables
-
Hyattsville, MD: National Center for Health Statistics
-
Arias E. United States life tables, 2011. In: National vital statistics reports. vol. 64. Hyattsville, MD: National Center for Health Statistics; 2015.
-
(2015)
National vital statistics reports
, vol.64
-
-
Arias, E.1
-
2
-
-
84866183226
-
Ageing as a risk factor for disease
-
Niccoli T, Partridge L. Ageing as a risk factor for disease. Curr Biol. 2012;22(17):R741-752.
-
(2012)
Curr Biol
, vol.22
, Issue.17
, pp. R741-752
-
-
Niccoli, T.1
Partridge, L.2
-
3
-
-
33644950249
-
Genetic influence on human lifespan and longevity
-
Hjelmborg JB, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, Kaprio J, Pedersen NL, Christensen K. Genetic influence on human lifespan and longevity. Hum Genet. 2006;119(3):312-21.
-
(2006)
Hum Genet
, vol.119
, Issue.3
, pp. 312-321
-
-
Hjelmborg, J.B.1
Iachine, I.2
Skytthe, A.3
Vaupel, J.W.4
McGue, M.5
Koskenvuo, M.6
Kaprio, J.7
Pedersen, N.L.8
Christensen, K.9
-
4
-
-
0030062815
-
The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900
-
Herskind AM, McGue M, Holm NV, Sorensen TI, Harvald B, Vaupel JW. The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900. Hum Genet. 1996;97(3):319-23.
-
(1996)
Hum Genet
, vol.97
, Issue.3
, pp. 319-323
-
-
Herskind, A.M.1
McGue, M.2
Holm, N.V.3
Sorensen, T.I.4
Harvald, B.5
Vaupel, J.W.6
-
5
-
-
0027482067
-
Longevity is moderately heritable in a sample of Danish twins born 1870-1880
-
McGue M, Vaupel JW, Holm N, Harvald B. Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J Gerontol. 1993;48(6):B237-244.
-
(1993)
J Gerontol
, vol.48
, Issue.6
, pp. B237-244
-
-
McGue, M.1
Vaupel, J.W.2
Holm, N.3
Harvald, B.4
-
6
-
-
84904741764
-
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
-
Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Hum Mol Genet. 2014;23(16):4420-32.
-
(2014)
Hum Mol Genet
, vol.23
, Issue.16
, pp. 4420-4432
-
-
Deelen, J.1
Beekman, M.2
Uh, H.W.3
Broer, L.4
Ayers, K.L.5
Tan, Q.6
Kamatani, Y.7
Bennet, A.M.8
Tamm, R.9
Trompet, S.10
-
7
-
-
84855955362
-
Genetic signatures of exceptional longevity in humans
-
Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, et al. Genetic signatures of exceptional longevity in humans. PLoS One. 2012;7(1), e29848.
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Sebastiani, P.1
Solovieff, N.2
Dewan, A.T.3
Walsh, K.M.4
Puca, A.5
Hartley, S.W.6
Melista, E.7
Andersen, S.8
Dworkis, D.A.9
Wilk, J.B.10
-
8
-
-
84959378751
-
Novel loci and pathways significantly associated with longevity
-
Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, et al. Novel loci and pathways significantly associated with longevity. Sci Rep. 2016;6:21243.
-
(2016)
Sci Rep
, vol.6
, pp. 21243
-
-
Zeng, Y.1
Nie, C.2
Min, J.3
Liu, X.4
Li, M.5
Chen, H.6
Xu, H.7
Wang, M.8
Ni, T.9
Li, Y.10
-
9
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013;45(12):1452-8.
-
(2013)
Nat Genet
, vol.45
, Issue.12
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
DeStafano, A.L.7
Bis, J.C.8
Beecham, G.W.9
Grenier-Boley, B.10
-
10
-
-
53749092728
-
Power for genetic association study of human longevity using the case-control design
-
Tan Q, Zhao JH, Zhang D, Kruse TA, Christensen K. Power for genetic association study of human longevity using the case-control design. Am J Epidemiol. 2008;168(8):890-6.
-
(2008)
Am J Epidemiol
, vol.168
, Issue.8
, pp. 890-896
-
-
Tan, Q.1
Zhao, J.H.2
Zhang, D.3
Kruse, T.A.4
Christensen, K.5
-
11
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard JK. Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet. 2001;69(1):124-37.
-
(2001)
Am J Hum Genet
, vol.69
, Issue.1
, pp. 124-137
-
-
Pritchard, J.K.1
-
12
-
-
67149095078
-
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip
-
Spencer CC, Su Z, Donnelly P, Marchini J. Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet. 2009;5(5), e1000477.
-
(2009)
PLoS Genet
, vol.5
, Issue.5
-
-
Spencer, C.C.1
Su, Z.2
Donnelly, P.3
Marchini, J.4
-
13
-
-
84874770275
-
Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect
-
Thornton KR, Foran AJ, Long AD. Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect. PLoS Genet. 2013;9(2), e1003258.
-
(2013)
PLoS Genet
, vol.9
, Issue.2
-
-
Thornton, K.R.1
Foran, A.J.2
Long, A.D.3
-
14
-
-
84925852614
-
Promoting health and longevity through diet: from model organisms to humans
-
Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 2015;161(1):106-18.
-
(2015)
Cell
, vol.161
, Issue.1
, pp. 106-118
-
-
Fontana, L.1
Partridge, L.2
-
15
-
-
34547223572
-
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial
-
Fontana L, Villareal DT, Weiss EP, Racette SB, Steger-May K, Klein S, Holloszy JO, Washington University School of Medicine CG. Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab. 2007;293(1):E197-202.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, Issue.1
, pp. E197-202
-
-
Fontana, L.1
Villareal, D.T.2
Weiss, E.P.3
Racette, S.B.4
Steger-May, K.5
Klein, S.6
Holloszy, J.O.7
-
16
-
-
84953227268
-
Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle
-
Yang L, Licastro D, Cava E, Veronese N, Spelta F, Rizza W, Bertozzi B, Villareal DT, Hotamisligil GS, Holloszy JO, et al. Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle. Cell Rep. 2016;14(3):422-8.
-
(2016)
Cell Rep
, vol.14
, Issue.3
, pp. 422-428
-
-
Yang, L.1
Licastro, D.2
Cava, E.3
Veronese, N.4
Spelta, F.5
Rizza, W.6
Bertozzi, B.7
Villareal, D.T.8
Hotamisligil, G.S.9
Holloszy, J.O.10
-
17
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993;366(6454):461-4.
-
(1993)
Nature
, vol.366
, Issue.6454
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
18
-
-
0030813398
-
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science. 1997;277(5328):942-6.
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
19
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science. 2001;292(5514):104-6.
-
(2001)
Science
, vol.292
, Issue.5514
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
Hafen, E.6
Leevers, S.J.7
Partridge, L.8
-
20
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, et al. Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J. 2008;22(3):807-18.
-
(2008)
FASEB J
, vol.22
, Issue.3
, pp. 807-818
-
-
Selman, C.1
Lingard, S.2
Choudhury, A.I.3
Batterham, R.L.4
Claret, M.5
Clements, M.6
Ramadani, F.7
Okkenhaug, K.8
Schuster, E.9
Blanc, E.10
-
21
-
-
77957372576
-
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span
-
Magwire MM, Yamamoto A, Carbone MA, Roshina NV, Symonenko AV, Pasyukova EG, Morozova TV, Mackay TF. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. PLoS Genet. 2010;6(7), e1001037.
-
(2010)
PLoS Genet
, vol.6
, Issue.7
-
-
Magwire, M.M.1
Yamamoto, A.2
Carbone, M.A.3
Roshina, N.V.4
Symonenko, A.V.5
Pasyukova, E.G.6
Morozova, T.V.7
Mackay, T.F.8
-
22
-
-
84899492285
-
A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster
-
Nakayama M, Ishibashi T, Ishikawa HO, Sato H, Usui T, Okuda T, Yashiro H, Ishikawa H, Taikou Y, Minami A, et al. A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster. BMC Genet. 2014;15:46.
-
(2014)
BMC Genet
, vol.15
, pp. 46
-
-
Nakayama, M.1
Ishibashi, T.2
Ishikawa, H.O.3
Sato, H.4
Usui, T.5
Okuda, T.6
Yashiro, H.7
Ishikawa, H.8
Taikou, Y.9
Minami, A.10
-
23
-
-
69249113100
-
Dissecting the genetics of longevity in Drosophila melanogaster
-
Paaby AB, Schmidt PS. Dissecting the genetics of longevity in Drosophila melanogaster. Fly (Austin). 2009;3(1):29-38.
-
(2009)
Fly (Austin)
, vol.3
, Issue.1
, pp. 29-38
-
-
Paaby, A.B.1
Schmidt, P.S.2
-
24
-
-
0036132290
-
The nature of quantitative genetic variation for Drosophila longevity
-
Mackay TF. The nature of quantitative genetic variation for Drosophila longevity. Mech Ageing Dev. 2002;123(2-3):95-104.
-
(2002)
Mech Ageing Dev
, vol.123
, Issue.2-3
, pp. 95-104
-
-
Mackay, T.F.1
-
25
-
-
0043095549
-
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity
-
De Luca M, Roshina NV, Geiger-Thornsberry GL, Lyman RF, Pasyukova EG, Mackay TF. Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nat Genet. 2003;34(4):429-33.
-
(2003)
Nat Genet
, vol.34
, Issue.4
, pp. 429-433
-
-
Luca, M.1
Roshina, N.V.2
Geiger-Thornsberry, G.L.3
Lyman, R.F.4
Pasyukova, E.G.5
Mackay, T.F.6
-
26
-
-
0030967939
-
Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster
-
Nuzhdin SV, Pasyukova EG, Dilda CL, Zeng ZB, Mackay TF. Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1997;94(18):9734-9.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.18
, pp. 9734-9739
-
-
Nuzhdin, S.V.1
Pasyukova, E.G.2
Dilda, C.L.3
Zeng, Z.B.4
Mackay, T.F.5
-
27
-
-
84863880314
-
Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits
-
King EG, Macdonald SJ, Long AD. Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits. Genetics. 2012;191(3):935-49.
-
(2012)
Genetics
, vol.191
, Issue.3
, pp. 935-949
-
-
King, E.G.1
Macdonald, S.J.2
Long, A.D.3
-
28
-
-
84863868317
-
Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource
-
King EG, Merkes CM, McNeil CL, Hoofer SR, Sen S, Broman KW, Long AD, Macdonald SJ. Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource. Genome Res. 2012;22(8):1558-66.
-
(2012)
Genome Res
, vol.22
, Issue.8
, pp. 1558-1566
-
-
King, E.G.1
Merkes, C.M.2
McNeil, C.L.3
Hoofer, S.R.4
Sen, S.5
Broman, K.W.6
Long, A.D.7
Macdonald, S.J.8
-
29
-
-
0028151261
-
Empirical threshold values for quantitative trait mapping
-
Churchill GA, Doerge RW. Empirical threshold values for quantitative trait mapping. Genetics. 1994;138(3):963-71.
-
(1994)
Genetics
, vol.138
, Issue.3
, pp. 963-971
-
-
Churchill, G.A.1
Doerge, R.W.2
-
30
-
-
84876996918
-
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 2013;14(4):R36.
-
(2013)
Genome Biol
, vol.14
, Issue.4
, pp. R36
-
-
Kim, D.1
Pertea, G.2
Trapnell, C.3
Pimentel, H.4
Kelley, R.5
Salzberg, S.L.6
-
31
-
-
65449136284
-
TopHat: discovering splice junctions with RNA-Seq
-
Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics. 2009;25(9):1105-11.
-
(2009)
Bioinformatics
, vol.25
, Issue.9
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
32
-
-
79952709611
-
Improving RNA-Seq expression estimates by correcting for fragment bias
-
Roberts A, Trapnell C, Donaghey J, Rinn JL, Pachter L. Improving RNA-Seq expression estimates by correcting for fragment bias. Genome Biol. 2011;12(3):R22.
-
(2011)
Genome Biol
, vol.12
, Issue.3
, pp. R22
-
-
Roberts, A.1
Trapnell, C.2
Donaghey, J.3
Rinn, J.L.4
Pachter, L.5
-
33
-
-
84872198346
-
Differential analysis of gene regulation at transcript resolution with RNA-seq
-
Trapnell C, Hendrickson DG, Sauvageau M, Goff L, Rinn JL, Pachter L. Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat Biotechnol. 2013;31(1):46-53.
-
(2013)
Nat Biotechnol
, vol.31
, Issue.1
, pp. 46-53
-
-
Trapnell, C.1
Hendrickson, D.G.2
Sauvageau, M.3
Goff, L.4
Rinn, J.L.5
Pachter, L.6
-
34
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, Salzberg SL, Wold BJ, Pachter L. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol. 2010;28(5):511-5.
-
(2010)
Nat Biotechnol
, vol.28
, Issue.5
, pp. 511-515
-
-
Trapnell, C.1
Williams, B.A.2
Pertea, G.3
Mortazavi, A.4
Kwan, G.5
Baren, M.J.6
Salzberg, S.L.7
Wold, B.J.8
Pachter, L.9
-
35
-
-
84959432052
-
Longevity GWAS Using the Drosophila Genetic Reference Panel
-
Ivanov DK, Escott-Price V, Ziehm M, Magwire MM, Mackay TF, Partridge L, Thornton JM. Longevity GWAS Using the Drosophila Genetic Reference Panel. J Gerontol A Biol Sci Med Sci. 2015;70(12):1470-8.
-
(2015)
J Gerontol A Biol Sci Med Sci
, vol.70
, Issue.12
, pp. 1470-1478
-
-
Ivanov, D.K.1
Escott-Price, V.2
Ziehm, M.3
Magwire, M.M.4
Mackay, T.F.5
Partridge, L.6
Thornton, J.M.7
-
36
-
-
84966559388
-
FlyBase: establishing a Gene Group resource for Drosophila melanogaster
-
Attrill H, Falls K, Goodman JL, Millburn GH, Antonazzo G, Rey AJ, Marygold SJ, FlyBase C. FlyBase: establishing a Gene Group resource for Drosophila melanogaster. Nucleic Acids Res. 2016;44(D1):D786-792.
-
(2016)
Nucleic Acids Res
, vol.44
, Issue.D1
, pp. D786-792
-
-
Attrill, H.1
Falls, K.2
Goodman, J.L.3
Millburn, G.H.4
Antonazzo, G.5
Rey, A.J.6
Marygold, S.J.7
-
37
-
-
80053641483
-
Increased transsulfuration mediates longevity and dietary restriction in Drosophila
-
Kabil H, Kabil O, Banerjee R, Harshman LG, Pletcher SD. Increased transsulfuration mediates longevity and dietary restriction in Drosophila. Proc Natl Acad Sci U S A. 2011;108(40):16831-6.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.40
, pp. 16831-16836
-
-
Kabil, H.1
Kabil, O.2
Banerjee, R.3
Harshman, L.G.4
Pletcher, S.D.5
-
38
-
-
0036132117
-
Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila
-
Curtsinger JW, Khazaeli AA. Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila. Mech Ageing Dev. 2002;123(2-3):81-93.
-
(2002)
Mech Ageing Dev
, vol.123
, Issue.2-3
, pp. 81-93
-
-
Curtsinger, J.W.1
Khazaeli, A.A.2
-
39
-
-
80052268617
-
Quantitative trait loci for longevity in heat-stressed Drosophila melanogaster
-
Defays R, Gomez FH, Sambucetti P, Scannapieco AC, Loeschcke V, Norry FM. Quantitative trait loci for longevity in heat-stressed Drosophila melanogaster. Exp Gerontol. 2011;46(10):819-26.
-
(2011)
Exp Gerontol
, vol.46
, Issue.10
, pp. 819-826
-
-
Defays, R.1
Gomez, F.H.2
Sambucetti, P.3
Scannapieco, A.C.4
Loeschcke, V.5
Norry, F.M.6
-
40
-
-
5144234956
-
Quantitative trait loci affecting life span in replicated populations of Drosophila melanogaster. I. Composite interval mapping
-
Forbes SN, Valenzuela RK, Keim P, Service PM. Quantitative trait loci affecting life span in replicated populations of Drosophila melanogaster. I. Composite interval mapping. Genetics. 2004;168(1):301-11.
-
(2004)
Genetics
, vol.168
, Issue.1
, pp. 301-311
-
-
Forbes, S.N.1
Valenzuela, R.K.2
Keim, P.3
Service, P.M.4
-
41
-
-
1542328246
-
Quantitative trait loci affecting natural variation in Drosophila longevity
-
Geiger-Thornsberry GL, Mackay TF. Quantitative trait loci affecting natural variation in Drosophila longevity. Mech Ageing Dev. 2004;125(3):179-89.
-
(2004)
Mech Ageing Dev
, vol.125
, Issue.3
, pp. 179-189
-
-
Geiger-Thornsberry, G.L.1
Mackay, T.F.2
-
42
-
-
35848966967
-
Speed-mapping quantitative trait loci using microarrays
-
Lai CQ, Leips J, Zou W, Roberts JF, Wollenberg KR, Parnell LD, Zeng ZB, Ordovas JM, Mackay TF. Speed-mapping quantitative trait loci using microarrays. Nat Methods. 2007;4(10):839-41.
-
(2007)
Nat Methods
, vol.4
, Issue.10
, pp. 839-841
-
-
Lai, C.Q.1
Leips, J.2
Zou, W.3
Roberts, J.F.4
Wollenberg, K.R.5
Parnell, L.D.6
Zeng, Z.B.7
Ordovas, J.M.8
Mackay, T.F.9
-
43
-
-
0033870603
-
Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density
-
Leips J, Mackay TF. Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density. Genetics. 2000;155(4):1773-88.
-
(2000)
Genetics
, vol.155
, Issue.4
, pp. 1773-1788
-
-
Leips, J.1
Mackay, T.F.2
-
44
-
-
0036791332
-
The complex genetic architecture of Drosophila life span
-
Leips J, Mackay TF. The complex genetic architecture of Drosophila life span. Exp Aging Res. 2002;28(4):361-90.
-
(2002)
Exp Aging Res
, vol.28
, Issue.4
, pp. 361-390
-
-
Leips, J.1
Mackay, T.F.2
-
45
-
-
22144454658
-
Survival analysis of life span quantitative trait loci in Drosophila melanogaster
-
Nuzhdin SV, Khazaeli AA, Curtsinger JW. Survival analysis of life span quantitative trait loci in Drosophila melanogaster. Genetics. 2005;170(2):719-31.
-
(2005)
Genetics
, vol.170
, Issue.2
, pp. 719-731
-
-
Nuzhdin, S.V.1
Khazaeli, A.A.2
Curtsinger, J.W.3
-
46
-
-
0037004596
-
Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes
-
Reiwitch SG, Nuzhdin SV. Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes. Genet Res. 2002;80(3):225-30.
-
(2002)
Genet Res
, vol.80
, Issue.3
, pp. 225-230
-
-
Reiwitch, S.G.1
Nuzhdin, S.V.2
-
47
-
-
0033979887
-
Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster
-
Vieira C, Pasyukova EG, Zeng ZB, Hackett JB, Lyman RF, Mackay TF. Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster. Genetics. 2000;154(1):213-27.
-
(2000)
Genetics
, vol.154
, Issue.1
, pp. 213-227
-
-
Vieira, C.1
Pasyukova, E.G.2
Zeng, Z.B.3
Hackett, J.B.4
Lyman, R.F.5
Mackay, T.F.6
-
48
-
-
13844286030
-
Environment-dependent survival of Drosophila melanogaster: a quantitative genetic analysis
-
Wang MH, Lazebny O, Harshman LG, Nuzhdin SV. Environment-dependent survival of Drosophila melanogaster: a quantitative genetic analysis. Aging Cell. 2004;3(3):133-40.
-
(2004)
Aging Cell
, vol.3
, Issue.3
, pp. 133-140
-
-
Wang, M.H.1
Lazebny, O.2
Harshman, L.G.3
Nuzhdin, S.V.4
-
49
-
-
33746458528
-
High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster
-
Wilson RH, Morgan TJ, Mackay TF. High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. Genetics. 2006;173(3):1455-63.
-
(2006)
Genetics
, vol.173
, Issue.3
, pp. 1455-1463
-
-
Wilson, R.H.1
Morgan, T.J.2
Mackay, T.F.3
-
50
-
-
84892492038
-
Genome-wide association study of extreme longevity in Drosophila melanogaster
-
Burke MK, King EG, Shahrestani P, Rose MR, Long AD. Genome-wide association study of extreme longevity in Drosophila melanogaster. Genome Biol Evol. 2014;6(1):1-11.
-
(2014)
Genome Biol Evol
, vol.6
, Issue.1
, pp. 1-11
-
-
Burke, M.K.1
King, E.G.2
Shahrestani, P.3
Rose, M.R.4
Long, A.D.5
-
51
-
-
84927509365
-
Dissecting complex traits using the Drosophila Synthetic Population Resource
-
Long AD, Macdonald SJ, King EG. Dissecting complex traits using the Drosophila Synthetic Population Resource. Trends Genet. 2014;30(11):488-95.
-
(2014)
Trends Genet
, vol.30
, Issue.11
, pp. 488-495
-
-
Long, A.D.1
Macdonald, S.J.2
King, E.G.3
-
52
-
-
84937881471
-
Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus
-
Lu HL, Wang JB, Brown MA, Euerle C, St Leger RJ. Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus. Sci Rep. 2015;5:12350.
-
(2015)
Sci Rep
, vol.5
, pp. 12350
-
-
Lu, H.L.1
Wang, J.B.2
Brown, M.A.3
Euerle, C.4
St Leger, R.J.5
-
53
-
-
47249142778
-
Revealing the architecture of gene regulation: the promise of eQTL studies
-
Gilad Y, Rifkin SA, Pritchard JK. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008;24(8):408-15.
-
(2008)
Trends Genet
, vol.24
, Issue.8
, pp. 408-415
-
-
Gilad, Y.1
Rifkin, S.A.2
Pritchard, J.K.3
-
54
-
-
84922282349
-
Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait
-
Torres JM, Gamazon ER, Parra EJ, Below JE, Valladares-Salgado A, Wacher N, Cruz M, Hanis CL, Cox NJ. Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. Am J Hum Genet. 2014;95(5):521-34.
-
(2014)
Am J Hum Genet
, vol.95
, Issue.5
, pp. 521-534
-
-
Torres, J.M.1
Gamazon, E.R.2
Parra, E.J.3
Below, J.E.4
Valladares-Salgado, A.5
Wacher, N.6
Cruz, M.7
Hanis, C.L.8
Cox, N.J.9
-
55
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000;25(1):25-9.
-
(2000)
Nat Genet
, vol.25
, Issue.1
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
Cherry, J.M.6
Davis, A.P.7
Dolinski, K.8
Dwight, S.S.9
Eppig, J.T.10
-
56
-
-
84946735654
-
Gene Ontology Consortium: going forward
-
Consortium GO. Gene Ontology Consortium: going forward. Nucleic Acids Res. 2015;43(Database issue):D1049-1056.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.DATABASE ISSUE
, pp. D1049-1056
-
-
Consortium, G.O.1
-
57
-
-
0037197870
-
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster
-
Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, Goldstein DB, Partridge L. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr Biol. 2002;12(9):712-23.
-
(2002)
Curr Biol
, vol.12
, Issue.9
, pp. 712-723
-
-
Pletcher, S.D.1
Macdonald, S.J.2
Marguerie, R.3
Certa, U.4
Stearns, S.C.5
Goldstein, D.B.6
Partridge, L.7
-
58
-
-
33846858644
-
Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping
-
Lai CQ, Parnell LD, Lyman RF, Ordovas JM, Mackay TF. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev. 2007;128(3):237-49.
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.3
, pp. 237-249
-
-
Lai, C.Q.1
Parnell, L.D.2
Lyman, R.F.3
Ordovas, J.M.4
Mackay, T.F.5
-
59
-
-
33746621756
-
Transcriptional profiling of aging in human muscle reveals a common aging signature
-
Zahn JM, Sonu R, Vogel H, Crane E, Mazan-Mamczarz K, Rabkin R, Davis RW, Becker KG, Owen AB, Kim SK. Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet. 2006;2(7), e115.
-
(2006)
PLoS Genet
, vol.2
, Issue.7
-
-
Zahn, J.M.1
Sonu, R.2
Vogel, H.3
Crane, E.4
Mazan-Mamczarz, K.5
Rabkin, R.6
Davis, R.W.7
Becker, K.G.8
Owen, A.B.9
Kim, S.K.10
-
60
-
-
2442719045
-
Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster
-
Landis GN, Abdueva D, Skvortsov D, Yang J, Rabin BE, Carrick J, Tavare S, Tower J. Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2004;101(20):7663-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.20
, pp. 7663-7668
-
-
Landis, G.N.1
Abdueva, D.2
Skvortsov, D.3
Yang, J.4
Rabin, B.E.5
Carrick, J.6
Tavare, S.7
Tower, J.8
-
61
-
-
34547631266
-
Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster
-
Zhan M, Yamaza H, Sun Y, Sinclair J, Li H, Zou S. Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster. Genome Res. 2007;17(8):1236-43.
-
(2007)
Genome Res
, vol.17
, Issue.8
, pp. 1236-1243
-
-
Zhan, M.1
Yamaza, H.2
Sun, Y.3
Sinclair, J.4
Li, H.5
Zou, S.6
-
62
-
-
84978460023
-
Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster
-
Carlson KA, Gardner K, Pashaj A, Carlson DJ, Yu F, Eudy JD, Zhang C, Harshman LG. Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster. Genet Res Int. 2015;2015:835624.
-
(2015)
Genet Res Int
, vol.2015
, pp. 835624
-
-
Carlson, K.A.1
Gardner, K.2
Pashaj, A.3
Carlson, D.J.4
Yu, F.5
Eudy, J.D.6
Zhang, C.7
Harshman, L.G.8
-
63
-
-
84948174122
-
Efficient Test and Visualization of Multi-Set Intersections
-
Wang M, Zhao Y, Zhang B. Efficient Test and Visualization of Multi-Set Intersections. Sci Rep. 2015;5:16923.
-
(2015)
Sci Rep
, vol.5
, pp. 16923
-
-
Wang, M.1
Zhao, Y.2
Zhang, B.3
-
64
-
-
84941177208
-
Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality
-
Clark RI, Salazar A, Yamada R, Fitz-Gibbon S, Morselli M, Alcaraz J, Rana A, Rera M, Pellegrini M, Ja WW, et al. Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality. Cell Rep. 2015;12(10):1656-67.
-
(2015)
Cell Rep
, vol.12
, Issue.10
, pp. 1656-1667
-
-
Clark, R.I.1
Salazar, A.2
Yamada, R.3
Fitz-Gibbon, S.4
Morselli, M.5
Alcaraz, J.6
Rana, A.7
Rera, M.8
Pellegrini, M.9
Ja, W.W.10
-
65
-
-
34547440528
-
Increased internal and external bacterial load during Drosophila aging without life-span trade-off
-
Ren C, Webster P, Finkel SE, Tower J. Increased internal and external bacterial load during Drosophila aging without life-span trade-off. Cell Metab. 2007;6(2):144-52.
-
(2007)
Cell Metab
, vol.6
, Issue.2
, pp. 144-152
-
-
Ren, C.1
Webster, P.2
Finkel, S.E.3
Tower, J.4
-
66
-
-
80053424095
-
The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
-
Wang JW, Brent JR, Tomlinson A, Shneider NA, McCabe BD. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011;121(10):4118-26.
-
(2011)
J Clin Invest
, vol.121
, Issue.10
, pp. 4118-4126
-
-
Wang, J.W.1
Brent, J.R.2
Tomlinson, A.3
Shneider, N.A.4
McCabe, B.D.5
-
67
-
-
23844531242
-
The hangover gene defines a stress pathway required for ethanol tolerance development
-
Scholz H, Franz M, Heberlein U. The hangover gene defines a stress pathway required for ethanol tolerance development. Nature. 2005;436(7052):845-7.
-
(2005)
Nature
, vol.436
, Issue.7052
, pp. 845-847
-
-
Scholz, H.1
Franz, M.2
Heberlein, U.3
-
68
-
-
0141865686
-
Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus
-
Symphorien S, Woodruff RC. Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus. J Gerontol A Biol Sci Med Sci. 2003;58(9):B782-787.
-
(2003)
J Gerontol A Biol Sci Med Sci
, vol.58
, Issue.9
, pp. B782-787
-
-
Symphorien, S.1
Woodruff, R.C.2
-
69
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin YJ, Seroude L, Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science. 1998;282(5390):943-6.
-
(1998)
Science
, vol.282
, Issue.5390
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
70
-
-
84908432541
-
Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells
-
Homem CC, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA. Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 2014;158(4):874-88.
-
(2014)
Cell
, vol.158
, Issue.4
, pp. 874-888
-
-
Homem, C.C.1
Steinmann, V.2
Burkard, T.R.3
Jais, A.4
Esterbauer, H.5
Knoblich, J.A.6
-
71
-
-
34250728186
-
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
-
Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD. Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. Genetics. 2007;176(2):1283-97.
-
(2007)
Genetics
, vol.176
, Issue.2
, pp. 1283-1297
-
-
Simonsen, A.1
Cumming, R.C.2
Lindmo, K.3
Galaviz, V.4
Cheng, S.5
Rusten, T.E.6
Finley, K.D.7
-
72
-
-
70349782312
-
Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain
-
Copeland JM, Cho J, Lo Jr T, Hur JH, Bahadorani S, Arabyan T, Rabie J, Soh J, Walker DW. Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain. Curr Biol. 2009;19(19):1591-8.
-
(2009)
Curr Biol
, vol.19
, Issue.19
, pp. 1591-1598
-
-
Copeland, J.M.1
Cho, J.2
Lo, T.3
Hur, J.H.4
Bahadorani, S.5
Arabyan, T.6
Rabie, J.7
Soh, J.8
Walker, D.W.9
-
73
-
-
84929501322
-
The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila
-
Merkling SH, Bronkhorst AW, Kramer JM, Overheul GJ, Schenck A, Van Rij RP. The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila. PLoS Pathog. 2015;11(4), e1004692.
-
(2015)
PLoS Pathog
, vol.11
, Issue.4
-
-
Merkling, S.H.1
Bronkhorst, A.W.2
Kramer, J.M.3
Overheul, G.J.4
Schenck, A.5
Rij, R.P.6
-
74
-
-
35448970692
-
Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes
-
Li A, Xie Z, Dong Y, McKay KM, McKee ML, Tanzi RE. Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet. 2007;16(21):2626-39.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.21
, pp. 2626-2639
-
-
Li, A.1
Xie, Z.2
Dong, Y.3
McKay, K.M.4
McKee, M.L.5
Tanzi, R.E.6
-
75
-
-
57749094923
-
Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster
-
Legan SK, Rebrin I, Mockett RJ, Radyuk SN, Klichko VI, Sohal RS, Orr WC. Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster. J Biol Chem. 2008;283(47):32492-9.
-
(2008)
J Biol Chem
, vol.283
, Issue.47
, pp. 32492-32499
-
-
Legan, S.K.1
Rebrin, I.2
Mockett, R.J.3
Radyuk, S.N.4
Klichko, V.I.5
Sohal, R.S.6
Orr, W.C.7
-
76
-
-
0034622645
-
Disruption of the microsomal glutathione S-transferase-like gene reduces life span of Drosophila melanogaster
-
Toba G, Aigaki T. Disruption of the microsomal glutathione S-transferase-like gene reduces life span of Drosophila melanogaster. Gene. 2000;253(2):179-87.
-
(2000)
Gene
, vol.253
, Issue.2
, pp. 179-187
-
-
Toba, G.1
Aigaki, T.2
-
77
-
-
79959380753
-
Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo
-
Liu J, Wu Q, He D, Ma T, Du L, Dui W, Guo X, Jiao R. Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo. J Genet Genomics. 2011;38(6):225-34.
-
(2011)
J Genet Genomics
, vol.38
, Issue.6
, pp. 225-234
-
-
Liu, J.1
Wu, Q.2
He, D.3
Ma, T.4
Du, L.5
Dui, W.6
Guo, X.7
Jiao, R.8
-
78
-
-
84898663884
-
Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function
-
Cuartero S, Fresan U, Reina O, Planet E, Espinas ML. Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function. EMBO J. 2014;33(6):637-47.
-
(2014)
EMBO J
, vol.33
, Issue.6
, pp. 637-647
-
-
Cuartero, S.1
Fresan, U.2
Reina, O.3
Planet, E.4
Espinas, M.L.5
-
79
-
-
0034919060
-
High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span
-
Landis G, Bhole D, Lu L, Tower J. High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span. Genetics. 2001;158(3):1167-76.
-
(2001)
Genetics
, vol.158
, Issue.3
, pp. 1167-1176
-
-
Landis, G.1
Bhole, D.2
Lu, L.3
Tower, J.4
-
80
-
-
84877095701
-
The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia
-
Petersen AJ, Katzenberger RJ, Wassarman DA. The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia. Genetics. 2013;194(1):133-42.
-
(2013)
Genetics
, vol.194
, Issue.1
, pp. 133-142
-
-
Petersen, A.J.1
Katzenberger, R.J.2
Wassarman, D.A.3
-
81
-
-
84941317162
-
Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species
-
Yu S, Jang Y, Paik D, Lee E, Park JJ. Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species. Biochem Biophys Res Commun. 2015;465(4):845-50.
-
(2015)
Biochem Biophys Res Commun
, vol.465
, Issue.4
, pp. 845-850
-
-
Yu, S.1
Jang, Y.2
Paik, D.3
Lee, E.4
Park, J.J.5
-
82
-
-
79251471784
-
Genetics and genomics of human ageing
-
Wheeler HE, Kim SK. Genetics and genomics of human ageing. Philos T R Soc B. 2011;366(1561):43-50.
-
(2011)
Philos T R Soc B
, vol.366
, Issue.1561
, pp. 43-50
-
-
Wheeler, H.E.1
Kim, S.K.2
-
83
-
-
48149112576
-
Diet and aging
-
Piper MD, Bartke A. Diet and aging. Cell Metab. 2008;8(2):99-104.
-
(2008)
Cell Metab
, vol.8
, Issue.2
, pp. 99-104
-
-
Piper, M.D.1
Bartke, A.2
-
84
-
-
0042422245
-
Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background
-
Spencer CC, Howell CE, Wright AR, Promislow DE. Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background. Aging Cell. 2003;2(2):123-30.
-
(2003)
Aging Cell
, vol.2
, Issue.2
, pp. 123-130
-
-
Spencer, C.C.1
Howell, C.E.2
Wright, A.R.3
Promislow, D.E.4
-
85
-
-
84901645732
-
GxGxE for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity
-
Zhu CT, Ingelmo P, Rand DM. GxGxE for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity. PLoS Genet. 2014;10(5), e1004354.
-
(2014)
PLoS Genet
, vol.10
, Issue.5
-
-
Zhu, C.T.1
Ingelmo, P.2
Rand, D.M.3
-
86
-
-
84894614543
-
A holidic medium for Drosophila melanogaster
-
Piper MD, Blanc E, Leitao-Goncalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, et al. A holidic medium for Drosophila melanogaster. Nat Methods. 2014;11(1):100-5.
-
(2014)
Nat Methods
, vol.11
, Issue.1
, pp. 100-105
-
-
Piper, M.D.1
Blanc, E.2
Leitao-Goncalves, R.3
Yang, M.4
He, X.5
Linford, N.J.6
Hoddinott, M.P.7
Hopfen, C.8
Soultoukis, G.A.9
Niemeyer, C.10
|