-
3
-
-
0024293278
-
Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms
-
Paterson A.H., et al. Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms. Nature 1988, 335:721-726.
-
(1988)
Nature
, vol.335
, pp. 721-726
-
-
Paterson, A.H.1
-
4
-
-
0024508964
-
Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
-
Lander E.S., Botstein D. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 1989, 121:185-199.
-
(1989)
Genetics
, vol.121
, pp. 185-199
-
-
Lander, E.S.1
Botstein, D.2
-
5
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678. Wellcome Trust Case Control Consortium.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
6
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter D., et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 2014, 42:D1001-D1006. 10.1093/nar/gkt1229.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D1001-D1006
-
-
Welter, D.1
-
7
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio T.A., et al. Finding the missing heritability of complex diseases. Nature 2009, 461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
8
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet. 2014, 46:234-244. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium.
-
(2014)
Nat. Genet.
, vol.46
, pp. 234-244
-
-
-
9
-
-
67149095078
-
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip
-
Spencer C.C.A., et al. Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet. 2009, 5:e1000477.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000477
-
-
Spencer, C.C.A.1
-
10
-
-
84863012360
-
The Drosophila melanogaster Genetic Reference Panel
-
Mackay T.F.C., et al. The Drosophila melanogaster Genetic Reference Panel. Nature 2012, 482:173-178.
-
(2012)
Nature
, vol.482
, pp. 173-178
-
-
Mackay, T.F.C.1
-
11
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N., Merikangas K. The future of genetic studies of complex human diseases. Science 1996, 273:1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
12
-
-
84904258306
-
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
-
Huang W., et al. Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Res. 2014, 24:1193-1208.
-
(2014)
Genome Res.
, vol.24
, pp. 1193-1208
-
-
Huang, W.1
-
13
-
-
68249120152
-
A multiparent advanced generation inter-cross to fine-map quantitative traits in Arabidopsis thaliana
-
Kover P.X., et al. A multiparent advanced generation inter-cross to fine-map quantitative traits in Arabidopsis thaliana. PLoS Genet. 2009, 5:e1000551.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000551
-
-
Kover, P.X.1
-
14
-
-
84863868317
-
Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource
-
King E.G., et al. Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource. Genome Res. 2012, 22:1558-1566.
-
(2012)
Genome Res.
, vol.22
, pp. 1558-1566
-
-
King, E.G.1
-
15
-
-
84863880314
-
Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits
-
King E.G., et al. Properties and power of the Drosophila Synthetic Population Resource for the routine dissection of complex traits. Genetics 2012, 191:935-949.
-
(2012)
Genetics
, vol.191
, pp. 935-949
-
-
King, E.G.1
-
16
-
-
33746540478
-
Genome-wide genetic association of complex traits in heterogeneous stock mice
-
Valdar W., et al. Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat. Genet. 2006, 38:879-887.
-
(2006)
Nat. Genet.
, vol.38
, pp. 879-887
-
-
Valdar, W.1
-
17
-
-
84879692177
-
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats
-
et al.
-
Rat Genome Sequencing and Mapping Consortium, et al. Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat. Genet. 2013, 45:767-775.
-
(2013)
Nat. Genet.
, vol.45
, pp. 767-775
-
-
-
18
-
-
0029391126
-
Statistical properties of segregating sites
-
Fu Y.X. Statistical properties of segregating sites. Theor. Popul. Biol. 1995, 48:172-197.
-
(1995)
Theor. Popul. Biol.
, vol.48
, pp. 172-197
-
-
Fu, Y.X.1
-
19
-
-
84863541347
-
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people
-
Nelson M.R., et al. An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science 2012, 337:100-104.
-
(2012)
Science
, vol.337
, pp. 100-104
-
-
Nelson, M.R.1
-
20
-
-
84863556835
-
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
-
Tennessen J.A., et al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 2012, 337:64-69.
-
(2012)
Science
, vol.337
, pp. 64-69
-
-
Tennessen, J.A.1
-
21
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard J.K. Are rare variants responsible for susceptibility to complex diseases?. Am. J. Hum. Genet. 2001, 69:124-137.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
22
-
-
84874770275
-
Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect
-
Thornton K.R., et al. Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect. PLoS Genet. 2013, 9:e1003258.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003258
-
-
Thornton, K.R.1
-
23
-
-
61449168010
-
A groupwise association test for rare mutations using a weighted sum statistic
-
Madsen B.E., Browning S.R. A groupwise association test for rare mutations using a weighted sum statistic. PLoS Genet. 2009, 5:e1000384.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000384
-
-
Madsen, B.E.1
Browning, S.R.2
-
24
-
-
80051499915
-
Rare-variant association testing for sequencing data with the sequence kernel association test
-
Wu M.C., et al. Rare-variant association testing for sequencing data with the sequence kernel association test. Am. J. Hum. Genet. 2011, 89:82-93.
-
(2011)
Am. J. Hum. Genet.
, vol.89
, pp. 82-93
-
-
Wu, M.C.1
-
25
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
Park J-H., et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 2010, 42:570-575.
-
(2010)
Nat. Genet.
, vol.42
, pp. 570-575
-
-
Park, J.-H.1
-
26
-
-
0026053091
-
Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster
-
Laurie C.C., et al. Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster. Genetics 1991, 129:489-499.
-
(1991)
Genetics
, vol.129
, pp. 489-499
-
-
Laurie, C.C.1
-
27
-
-
0028031431
-
The effect of an intronic polymorphism on alcohol dehydrogenase expression in Drosophila melanogaster
-
Laurie C.C., Stam L.F. The effect of an intronic polymorphism on alcohol dehydrogenase expression in Drosophila melanogaster. Genetics 1994, 138:379-385.
-
(1994)
Genetics
, vol.138
, pp. 379-385
-
-
Laurie, C.C.1
Stam, L.F.2
-
28
-
-
0030453209
-
Molecular dissection of a major gene effect on a quantitative trait: the level of alcohol dehydrogenase expression in Drosophila melanogaster
-
Stam L.F., Laurie C.C. Molecular dissection of a major gene effect on a quantitative trait: the level of alcohol dehydrogenase expression in Drosophila melanogaster. Genetics 1996, 144:1559-1564.
-
(1996)
Genetics
, vol.144
, pp. 1559-1564
-
-
Stam, L.F.1
Laurie, C.C.2
-
29
-
-
0023318482
-
Post-translational control of alcohol dehydrogenase levels in Drosophila melanogaster
-
King J.J., McDonald J.F. Post-translational control of alcohol dehydrogenase levels in Drosophila melanogaster. Genetics 1987, 115:693-699.
-
(1987)
Genetics
, vol.115
, pp. 693-699
-
-
King, J.J.1
McDonald, J.F.2
-
30
-
-
84907978425
-
Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation intercross population
-
Marriage T., et al. Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation intercross population. Genetics 2014, 198. 10.1534/genetics.114.162107.
-
(2014)
Genetics
, vol.198
-
-
Marriage, T.1
-
31
-
-
84883614860
-
The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans
-
Kislukhin G., et al. The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans. G3 2013, 3:1301-1310.
-
(2013)
G3
, vol.3
, pp. 1301-1310
-
-
Kislukhin, G.1
-
32
-
-
84908003427
-
Using Drosophila melanogaster to identify chemotherapy toxicity genes
-
King E.G., et al. Using Drosophila melanogaster to identify chemotherapy toxicity genes. Genetics 2014, 198. 10.1534/genetics.114.161968.
-
(2014)
Genetics
, vol.198
-
-
King, E.G.1
-
33
-
-
84901611017
-
Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity
-
King E.G., et al. Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity. PLoS Genet. 2014, 10:e1004322.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004322
-
-
King, E.G.1
-
34
-
-
62449248382
-
Cis-regulatory variation is typically polyallelic in Drosophila
-
Gruber J.D., Long A.D. Cis-regulatory variation is typically polyallelic in Drosophila. Genetics 2008, 181:661-670.
-
(2008)
Genetics
, vol.181
, pp. 661-670
-
-
Gruber, J.D.1
Long, A.D.2
-
35
-
-
79955556526
-
Genetic architecture of regulatory variation in Arabidopsis thaliana
-
Zhang X., et al. Genetic architecture of regulatory variation in Arabidopsis thaliana. Genome Res. 2011, 21:725-733.
-
(2011)
Genome Res.
, vol.21
, pp. 725-733
-
-
Zhang, X.1
-
36
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen T., et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 2013, 501:506-511.
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
-
37
-
-
84878475112
-
Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data
-
Powell J.E., et al. Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data. PLoS Genet. 2013, 9:e1003502.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003502
-
-
Powell, J.E.1
-
38
-
-
34250784724
-
Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster
-
Macdonald S.J., Long A.D. Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster. Genetics 2006, 176:1261-1281.
-
(2006)
Genetics
, vol.176
, pp. 1261-1281
-
-
Macdonald, S.J.1
Long, A.D.2
-
39
-
-
79957658264
-
Genetic analysis of complex traits in the emerging collaborative cross
-
Aylor D.L., et al. Genetic analysis of complex traits in the emerging collaborative cross. Genome Res. 2011, 21:1213-1222.
-
(2011)
Genome Res.
, vol.21
, pp. 1213-1222
-
-
Aylor, D.L.1
-
40
-
-
0036741796
-
GAL4 system in Drosophila: a fly geneticist's swiss army knife
-
Duffy J.B. GAL4 system in Drosophila: a fly geneticist's swiss army knife. Genesis 2002, 34:1-15.
-
(2002)
Genesis
, vol.34
, pp. 1-15
-
-
Duffy, J.B.1
-
41
-
-
84900458436
-
Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila
-
Gratz S.J., et al. Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila. Genetics 2014, 196:961-971.
-
(2014)
Genetics
, vol.196
, pp. 961-971
-
-
Gratz, S.J.1
-
42
-
-
0016669094
-
Evolution at two levels in humans and chimpanzees
-
King M.C., Wilson A.C. Evolution at two levels in humans and chimpanzees. Science 1975, 188:107-116.
-
(1975)
Science
, vol.188
, pp. 107-116
-
-
King, M.C.1
Wilson, A.C.2
-
43
-
-
26444519157
-
The quantitative genetics of transcription
-
Gibson G., Weir B. The quantitative genetics of transcription. Trends Genet. 2005, 21:616-623.
-
(2005)
Trends Genet.
, vol.21
, pp. 616-623
-
-
Gibson, G.1
Weir, B.2
-
44
-
-
47249142778
-
Revealing the architecture of gene regulation: the promise of eQTL studies
-
Gilad Y., et al. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008, 24:408-415.
-
(2008)
Trends Genet.
, vol.24
, pp. 408-415
-
-
Gilad, Y.1
-
45
-
-
84857111200
-
DNase I sensitivity QTLs are a major determinant of human expression variation
-
Degner J.F., et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 2012, 482:390-394.
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
-
46
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression QTLs
-
Gaffney D.J., et al. Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012, 13:R7.
-
(2012)
Genome Biol.
, vol.13
, pp. R7
-
-
Gaffney, D.J.1
-
47
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J., King M-C. Genetic heterogeneity in human disease. Cell 2010, 141:210-217.
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.-C.2
-
48
-
-
79952719931
-
Analysis of natural allelic variation in Arabidopsis using a multiparent recombinant inbred line population
-
Huang X., et al. Analysis of natural allelic variation in Arabidopsis using a multiparent recombinant inbred line population. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:4488-4493.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 4488-4493
-
-
Huang, X.1
-
49
-
-
84857433366
-
Ten years of the Collaborative Cross
-
Threadgill D.W., Churchill G.A. Ten years of the Collaborative Cross. Genetics 2012, 190:291-294.
-
(2012)
Genetics
, vol.190
, pp. 291-294
-
-
Threadgill, D.W.1
Churchill, G.A.2
-
50
-
-
84886099953
-
High-resolution mapping of complex traits with a four-parent advanced intercross yeast population
-
Cubillos F.A., et al. High-resolution mapping of complex traits with a four-parent advanced intercross yeast population. Genetics 2013, 195:1141-1155.
-
(2013)
Genetics
, vol.195
, pp. 1141-1155
-
-
Cubillos, F.A.1
-
51
-
-
68449094455
-
Genetic properties of the maize nested association mapping population
-
McMullen M.D., et al. Genetic properties of the maize nested association mapping population. Science 2009, 325:737-740.
-
(2009)
Science
, vol.325
, pp. 737-740
-
-
McMullen, M.D.1
-
52
-
-
84888588595
-
Abundance and distribution of transposable elements in two Drosophila QTL mapping resources
-
Cridland J.M., et al. Abundance and distribution of transposable elements in two Drosophila QTL mapping resources. Mol. Biol. Evol. 2013, 30:2311-2327.
-
(2013)
Mol. Biol. Evol.
, vol.30
, pp. 2311-2327
-
-
Cridland, J.M.1
-
53
-
-
54449098752
-
Rapid SNP discovery and genetic mapping using sequenced RAD markers
-
Baird N.A., et al. Rapid SNP discovery and genetic mapping using sequenced RAD markers. PLoS ONE 2008, 3:e3376.
-
(2008)
PLoS ONE
, vol.3
, pp. e3376
-
-
Baird, N.A.1
-
54
-
-
84863115856
-
The genome architecture of the Collaborative Cross mouse genetic reference population
-
Collaborative Cross Consortium
-
The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics 2012, 190:389-401. Collaborative Cross Consortium.
-
(2012)
Genetics
, vol.190
, pp. 389-401
-
-
|