Histone deacetylase 6 structure and molecular basis of catalysis and inhibition

Nature Chemical Biology

Volumn 12, Issue 9, 2016, Pages 741-747

  Hai, Yang ^a   Christianson, David W ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BELINOSTAT; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; N HYDROXY 4 [2 [(2 HYDROXYETHYL)(PHENYL)AMINO] 2 OXOETHYL]BENZAMIDE; PANOBINOSTAT; UNCLASSIFIED DRUG; ZEBRAFISH PROTEIN; ZEBRAFISH PROTEIN CD1; ZEBRAFISH PROTEIN CD2; HISTONE DEACETYLASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZEBRA FISH; ANIMAL; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOCATALYSIS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; ZEBRAFISH;

EID: 84980383714     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2134     Document Type: Article

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