Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens

PLoS Computational Biology

Volumn 12, Issue 7, 2016, Pages

  Chasman, Deborah ^a   Walters, Kevin B ^b,g   Lopes, Tiago J S ^b   Eisfeld, Amie J ^b   Kawaoka, Yoshihiro ^b,c,d   Roy, Sushmita ^a,e,f  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c THE UNIVERSITY OF TOKYO   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e University of Wisconsin   (United States)

^f UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^g Southern Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIGITAL STORAGE; DISEASES; INTERFERONS; MAMMALS; TRANSCRIPTION; VIRUSES;

COMPLEX REGULATORY NETWORK; HOST RESPONSE; INFECTIOUS AGENTS; MAMMALIAN HOSTS; NETWORK MODELS; PATHOGENIC INFECTIONS; PROTEOMICS; REGULATORY NETWORK; REGULATORY PROTEIN; TRANSCRIPTOMICS;

CELL DEATH;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 7; JANUS KINASE; NMI PROTEIN; PEPTIDES AND PROTEINS; PROTEOME; STAT1 PROTEIN; TCEB1 PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE CLUSTER; GENE EXPRESSION; GENE REGULATORY NETWORK; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; RNA SPLICING; SIGNAL TRANSDUCTION; VALIDATION PROCESS; VIRUS DNA CELL DNA INTERACTION; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BIOLOGICAL MODEL; GENE EXPRESSION PROFILING; GENETICS; HOST PATHOGEN INTERACTION; INFLUENZA; PROCEDURES; PROTEOMICS; SYSTEMS BIOLOGY;

ANIMALS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA, HUMAN; MICE; MODELS, BIOLOGICAL; PROTEOME; PROTEOMICS; SYSTEMS BIOLOGY; TRANSCRIPTOME;

EID: 84980043254     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1005013     Document Type: Article

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