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Volumn 24, Issue 11, 2014, Pages 1869-1880

Linking signaling pathways to transcriptional programs in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HIGH MOBILITY GROUP PROTEIN; INTERFERON REGULATORY FACTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN BCL 2; PROTEIN MSH6; SMAD4 PROTEIN; STAT5A PROTEIN; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR SOX9; ANTINEOPLASTIC AGENT; TRANSCRIPTION FACTOR;

EID: 84929456295     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.173039.114     Document Type: Article
Times cited : (52)

References (75)
  • 4
    • 30044450499 scopus 로고    scopus 로고
    • Antitumor effect of E1A in ovarian cancer by cytoplasmic sequestration of activated ERK by PEA15
    • Bartholomeusz C, Itamochi H, Nitta M, Saya H, Ginsberg MH, Ueno NT. 2006. Antitumor effect of E1A in ovarian cancer by cytoplasmic sequestration of activated ERK by PEA15. Oncogene 25: 79-90.
    • (2006) Oncogene , vol.25 , pp. 79-90
    • Bartholomeusz, C.1    Itamochi, H.2    Nitta, M.3    Saya, H.4    Ginsberg, M.H.5    Ueno, N.T.6
  • 5
    • 77949748262 scopus 로고    scopus 로고
    • PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase
    • Bartholomeusz C, Gonzalez-Angulo AM, Kazansky A, Krishnamurthy S, Liu P, Yuan LX, Yamasaki F, Liu S, Hayashi N, Zhang D, et al. 2010. PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase. Clin Cancer Res 16: 1802-1811.
    • (2010) Clin Cancer Res , vol.16 , pp. 1802-1811
    • Bartholomeusz, C.1    Gonzalez-Angulo, A.M.2    Kazansky, A.3    Krishnamurthy, S.4    Liu, P.5    Yuan, L.X.6    Yamasaki, F.7    Liu, S.8    Hayashi, N.9    Zhang, D.10
  • 6
    • 79959508436 scopus 로고    scopus 로고
    • Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer
    • Baselga J. 2011. Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer. Oncologist 16 (Suppl 1): 12-19.
    • (2011) Oncologist , vol.16 , pp. 12-19
    • Baselga, J.1
  • 9
    • 0030358586 scopus 로고    scopus 로고
    • High-mobility-group chromosomal proteins: Architectural components that facilitate chromatin function
    • Bustin M, Reeves R. 1996. High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function. Prog Nucleic Acid Res Mol Biol 54: 35-100.
    • (1996) Prog Nucleic Acid Res Mol Biol , vol.54 , pp. 35-100
    • Bustin, M.1    Reeves, R.2
  • 11
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • The Cancer Genome Atlas Network. 2012. Comprehensive molecular portraits of human breast tumours. Nature 490: 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 13
    • 78751475720 scopus 로고    scopus 로고
    • Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment
    • Chakravarty G, Rider B, Mondal D. 2011b. Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. Cancer Biol Ther 11: 71-83.
    • (2011) Cancer Biol Ther , vol.11 , pp. 71-83
    • Chakravarty, G.1    Rider, B.2    Mondal, D.3
  • 14
    • 77957357280 scopus 로고    scopus 로고
    • Differential response of triple-negative breast cancer to a docetaxel and carboplatin-based neoadjuvant treatment
    • Chang HR, Glaspy J, Allison MA, Kass FC, Elashoff R, Chung DU, Gornbein J. 2010. Differential response of triple-negative breast cancer to a docetaxel and carboplatin-based neoadjuvant treatment. Cancer 116: 4227-4237.
    • (2010) Cancer , vol.116 , pp. 4227-4237
    • Chang, H.R.1    Glaspy, J.2    Allison, M.A.3    Kass, F.C.4    Elashoff, R.5    Chung, D.U.6    Gornbein, J.7
  • 15
    • 0033064093 scopus 로고    scopus 로고
    • Interactions of high mobility group box proteins with DNA and chromatin
    • Churchill ME, Changela A, Dow LK, Krieg AJ. 1999. Interactions of high mobility group box proteins with DNA and chromatin. Methods Enzymol 304: 99-133.
    • (1999) Methods Enzymol , vol.304 , pp. 99-133
    • Churchill, M.E.1    Changela, A.2    Dow, L.K.3    Krieg, A.J.4
  • 20
    • 34250652449 scopus 로고    scopus 로고
    • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
    • Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, Haibe-Kains B, Viale G, Delorenzi M, Zhang Y, d'Assignies MS, et al. 2007. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13: 3207-3214.
    • (2007) Clin Cancer Res , vol.13 , pp. 3207-3214
    • Desmedt, C.1    Piette, F.2    Loi, S.3    Wang, Y.4    Lallemand, F.5    Haibe-Kains, B.6    Viale, G.7    Delorenzi, M.8    Zhang, Y.9    D'Assignies, M.S.10
  • 21
    • 84858381626 scopus 로고    scopus 로고
    • NICE guidance on rituximab for first-line treatment of symptomatic stage III-IV follicular lymphoma in previously untreated patients
    • Doss S, Garrett Z, Sutcliffe F, Stevens A. 2012. NICE guidance on rituximab for first-line treatment of symptomatic stage III-IV follicular lymphoma in previously untreated patients. Lancet Oncol 13: 128-130.
    • (2012) Lancet Oncol , vol.13 , pp. 128-130
    • Doss, S.1    Garrett, Z.2    Sutcliffe, F.3    Stevens, A.4
  • 24
    • 33845348883 scopus 로고    scopus 로고
    • Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma
    • Francis LK, Alsayed Y, Leleu X, Jia X, Singha UK, Anderson J, Timm M, Ngo H, Lu G, Huston A, et al. 2006. Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma. Clin Cancer Res 12: 6826-6835.
    • (2006) Clin Cancer Res , vol.12 , pp. 6826-6835
    • Francis, L.K.1    Alsayed, Y.2    Leleu, X.3    Jia, X.4    Singha, U.K.5    Anderson, J.6    Timm, M.7    Ngo, H.8    Lu, G.9    Huston, A.10
  • 25
    • 77950537175 scopus 로고    scopus 로고
    • Regularization paths for generalized linear models via coordinate descent
    • Friedman J, Hastie T, Tibshirani R. 2010. Regularization paths for generalized linear models via coordinate descent. J Stat Softw 33: 1-22.
    • (2010) J Stat Softw , vol.33 , pp. 1-22
    • Friedman, J.1    Hastie, T.2    Tibshirani, R.3
  • 26
    • 84865202387 scopus 로고    scopus 로고
    • 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner
    • Gagliardi PA, di Blasio L, Orso F, Seano G, Sessa R, Taverna D, Bussolino F, Primo L. 2012. 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner. Neoplasia 14: 719-731.
    • (2012) Neoplasia , vol.14 , pp. 719-731
    • Gagliardi, P.A.1    Di Blasio, L.2    Orso, F.3    Seano, G.4    Sessa, R.5    Taverna, D.6    Bussolino, F.7    Primo, L.8
  • 27
    • 84856265603 scopus 로고    scopus 로고
    • Pharmacologic inhibition of mTOR improves lapatinib sensitivity in HER2-overexpressing breast cancer cells with primary trastuzumab resistance
    • Gayle SS, Arnold SL, O'Regan RM, Nahta R. 2012. Pharmacologic inhibition of mTOR improves lapatinib sensitivity in HER2-overexpressing breast cancer cells with primary trastuzumab resistance. Anticancer Agents Med Chem 12: 151-162.
    • (2012) Anticancer Agents Med Chem , vol.12 , pp. 151-162
    • Gayle, S.S.1    Arnold, S.L.2    O'Regan, R.M.3    Nahta, R.4
  • 33
    • 77951115122 scopus 로고    scopus 로고
    • International network of cancer genome projects
    • The International Cancer Genome Consortium. 2010. International network of cancer genome projects. Nature 464: 993-998.
    • (2010) Nature , vol.464 , pp. 993-998
  • 36
    • 84861123691 scopus 로고    scopus 로고
    • Ten years of pathway analysis: Current approaches and outstanding challenges
    • Khatri P, Sirota M, Butte AJ. 2012. Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput Biol 8: e1002375.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002375
    • Khatri, P.1    Sirota, M.2    Butte, A.J.3
  • 40
    • 79960008610 scopus 로고    scopus 로고
    • ResponseNet: Revealing signaling and regulatory networks linking genetic and transcriptomic screening data
    • Lan A, Smoly IY, Rapaport G, Lindquist S, Fraenkel E, Yeger-Lotem E. 2011. ResponseNet: revealing signaling and regulatory networks linking genetic and transcriptomic screening data. Nucleic Acids Res 39: W424-429.
    • (2011) Nucleic Acids Res , vol.39 , pp. W424-429
    • Lan, A.1    Smoly, I.Y.2    Rapaport, G.3    Lindquist, S.4    Fraenkel, E.5    Yeger-Lotem, E.6
  • 44
    • 27544508293 scopus 로고    scopus 로고
    • The transcription factor Ets-1 in breast cancer
    • Lincoln DW 2nd, Bove K. 2005. The transcription factor Ets-1 in breast cancer. Front Biosci 10: 506-511.
    • (2005) Front Biosci , vol.10 , pp. 506-511
    • Lincoln, D.W.1    Bove, K.2
  • 45
    • 70350514636 scopus 로고    scopus 로고
    • NFAT proteins: Emerging roles in cancer progression
    • Mancini M, Toker A. 2009. NFAT proteins: emerging roles in cancer progression. Nat Rev Cancer 9: 810-820.
    • (2009) Nat Rev Cancer , vol.9 , pp. 810-820
    • Mancini, M.1    Toker, A.2
  • 48
    • 0038018480 scopus 로고    scopus 로고
    • Expression of the CCAAT/enhancer-binding proteins C/EBPa, C/EBPb and C/EBPd in breast cancer: Correlations with clinicopathologic parameters and cell-cycle regulatory proteins
    • Milde-Langosch K, Loning T, Bamberger AM. 2003. Expression of the CCAAT/enhancer-binding proteins C/EBPa, C/EBPb and C/EBPd in breast cancer: correlations with clinicopathologic parameters and cell-cycle regulatory proteins. Breast Cancer Res Treat 79: 175-185.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 175-185
    • Milde-Langosch, K.1    Loning, T.2    Bamberger, A.M.3
  • 56
    • 77952849736 scopus 로고    scopus 로고
    • High-mobility group A (HMGA) proteins and breast cancer
    • Peluso S, Chiappetta G. 2010. High-mobility group A (HMGA) proteins and breast cancer. Breast Care (Basel) 5: 81-85.
    • (2010) Breast Care (Basel) , vol.5 , pp. 81-85
    • Peluso, S.1    Chiappetta, G.2
  • 58
    • 78650380858 scopus 로고    scopus 로고
    • Thyroid transcription factor-1 expression in breast carcinomas
    • Robens J, Goldstein L, Gown AM, Schnitt SJ. 2010. Thyroid transcription factor-1 expression in breast carcinomas. Am J Surg Pathol 34: 1881-1885.
    • (2010) Am J Surg Pathol , vol.34 , pp. 1881-1885
    • Robens, J.1    Goldstein, L.2    Gown, A.M.3    Schnitt, S.J.4
  • 59
    • 6944244084 scopus 로고    scopus 로고
    • A module map showing conditional activity of expression modules in cancer
    • Segal E, Friedman N, Koller D, Regev A. 2004. A module map showing conditional activity of expression modules in cancer. Nat Genet 36: 1090-1098.
    • (2004) Nat Genet , vol.36 , pp. 1090-1098
    • Segal, E.1    Friedman, N.2    Koller, D.3    Regev, A.4
  • 62
    • 0037028211 scopus 로고    scopus 로고
    • Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival inbreast cancer
    • Span PN, Manders P, Heuvel JJ, Thomas CM, Bosch RR, Beex LV, Sweep CG. 2002. Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival inbreast cancer. Oncogene 21: 8506-8509.
    • (2002) Oncogene , vol.21 , pp. 8506-8509
    • Span, P.N.1    Manders, P.2    Heuvel, J.J.3    Thomas, C.M.4    Bosch, R.R.5    Beex, L.V.6    Sweep, C.G.7
  • 63
    • 84866022996 scopus 로고    scopus 로고
    • Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer
    • Switzer CH, Cheng RY, Ridnour LA, Glynn SA, Ambs S, Wink DA. 2012. Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer. Breast Cancer Res 14: R125.
    • (2012) Breast Cancer Res , vol.14 , pp. R125
    • Switzer, C.H.1    Cheng, R.Y.2    Ridnour, L.A.3    Glynn, S.A.4    Ambs, S.5    Wink, D.A.6
  • 66
    • 84858701995 scopus 로고    scopus 로고
    • Targeting EGFR in triple negative breast cancer
    • Ueno NT, Zhang D. 2011. Targeting EGFR in triple negative breast cancer. J Cancer 2: 324-328.
    • (2011) J Cancer , vol.2 , pp. 324-328
    • Ueno, N.T.1    Zhang, D.2
  • 68
    • 77954195272 scopus 로고    scopus 로고
    • Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM
    • Vaske CJ, Benz SC, Sanborn JZ, Earl D, Szeto C, Zhu J, Haussler D, Stuart JM. 2010. Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM. Bioinformatics 26: i237-i245.
    • (2010) Bioinformatics , vol.26 , pp. i237-i245
    • Vaske, C.J.1    Benz, S.C.2    Sanborn, J.Z.3    Earl, D.4    Szeto, C.5    Zhu, J.6    Haussler, D.7    Stuart, J.M.8
  • 71
    • 45949110405 scopus 로고    scopus 로고
    • Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor a pathway
    • Wilson BJ, Giguere V. 2008. Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor a pathway. Mol Cancer 7: 49.
    • (2008) Mol Cancer , vol.7 , pp. 49
    • Wilson, B.J.1    Giguere, V.2
  • 73
    • 33744948986 scopus 로고    scopus 로고
    • NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2
    • Yiu GK, Toker A. 2006. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. J Biol Chem 281: 12210-12217.
    • (2006) J Biol Chem , vol.281 , pp. 12210-12217
    • Yiu, G.K.1    Toker, A.2
  • 75
    • 65349107367 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein b: Its role in breast cancer and associations with receptor tyrosine kinases
    • Zahnow CA. 2009. CCAAT/enhancer-binding protein b: its role in breast cancer and associations with receptor tyrosine kinases. Expert Rev Mol Med 11: e12.
    • (2009) Expert Rev Mol Med , vol.11 , pp. e12
    • Zahnow, C.A.1


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