NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart

Circulation Research

Volumn 119, Issue 5, 2016, Pages 596-606

  Matsuda, Takahisa ^a   Zhai, Peiyong ^a   Sciarretta, Sebastiano ^b,c   Zhang, Yu ^a   Jeong, Jae Im ^a   Ikeda, Shohei ^a   Park, Jiyeon ^a   Hsu, Chiao Po ^d   Tian, Bin ^a   Pan, Duojia ^e   Sadoshima, Junichi ^a   Del Re, Dominic P ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b IRCCS NEUROMED   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

apoptosis; cardiomyocyte; neurofibromin 2; oxidative stress; reperfusion injury

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; MAMMALIAN STERILE 20 LIKE KINASE 1; MERLIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PEPTIDES AND PROTEINS; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN; HIPPO PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; EX VIVO STUDY; GENE EXPRESSION REGULATION; GENE INACTIVATION; HIPPO SIGNALING; IN VIVO STUDY; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CELLS, CULTURED; HYDROGEN PEROXIDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NEUROFIBROMIN 2; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84980025187     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.308586     Document Type: Article

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