Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model

Circulation Research

Volumn 115, Issue 3, 2014, Pages 354-363

  Lin, Zhiqiang ^a   Von Gise, Alexander ^c   Zhou, Pingzhu ^a   Gu, Fei ^a   Ma, Qing ^a   Jiang, Jianming ^b   Yau, Allan L ^a   Buck, Jessica N ^a   Gouin, Katryna A ^a   Van Gorp, Pim R R ^d   Zhou, Bin ^a,f   Chen, Jinghai ^a   Seidman, Jonathan G ^b   Wang, Da Zhi ^e   Pu, William T ^a,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e HARVARD STEM CELL INSTITUTE   (United States)

^f Chinese Academy of Sciences   (China)

Author keywords

heart failure; myocardial infarction; regeneration; survival

Indexed keywords

DOXYCYCLINE; PROTEIN; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN;

ADENO ASSOCIATED VIRUS; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION PROFILING; GENE THERAPY; HEART EJECTION FRACTION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; LONG TERM CARE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

HEART FAILURE; MYOCARDIAL INFARCTION; REGENERATION; SURVIVAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CARDIOMEGALY; CELL PROLIFERATION; CELL SURVIVAL; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; PHOSPHOPROTEINS; REGENERATION; SURVIVAL RATE; TRANSCRIPTOME;

EID: 84904746093     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.303632     Document Type: Article

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