-
1
-
-
0033485979
-
Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations
-
Gutmann, D. H., Haipek, C. A. & Hoang Lu, K. Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations. J. Neurosci. Res. 58, 706-716 (1999).
-
(1999)
J. Neurosci. Res
, vol.58
, pp. 706-716
-
-
Gutmann, D.H.1
Haipek, C.A.2
Hoang Lu, K.3
-
2
-
-
0033607687
-
Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF
-
Gonzalez-Agosti, C., Wiederhold, T., Herndon, M. E., Gusella, J. & Ramesh, V. Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF. J. Biol. Chem. 274, 34438-34442 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 34438-34442
-
-
Gonzalez-Agosti, C.1
Wiederhold, T.2
Herndon, M.E.3
Gusella, J.4
Ramesh, V.5
-
3
-
-
0034670030
-
Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between marlin and ezrin, suggests modulation of ERM proteins by merlin
-
Meng, J. J. et al. Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between marlin and ezrin, suggests modulation of ERM proteins by merlin. J. Neurosci. Res. 62, 491-502 (2000).
-
(2000)
J. Neurosci. Res
, vol.62
, pp. 491-502
-
-
Meng, J.J.1
-
4
-
-
0037155916
-
Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization
-
Kissil, J. L., Johnson, K. C., Eckman, M. S. & Jacks, T. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. J. Biol. Chem. 277, 10394-10399 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 10394-10399
-
-
Kissil, J.L.1
Johnson, K.C.2
Eckman, M.S.3
Jacks, T.4
-
5
-
-
0037059807
-
p21-activated kinase links Rac/Cdc42 signaling to merlin
-
Xiao, G. H., Beeser, A., Chernoff, J. & Testa, J. R. p21-activated kinase links Rac/Cdc42 signaling to merlin. J. Biol. Chem. 277 883-886 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 883-886
-
-
Xiao, G.H.1
Beeser, A.2
Chernoff, J.3
Testa, J.R.4
-
6
-
-
0035871299
-
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
-
Morrison, H. et al. The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. Genes Dev. 15, 968-980 (2001).
-
(2001)
Genes Dev
, vol.15
, pp. 968-980
-
-
Morrison, H.1
-
7
-
-
9144234897
-
Serine 518 phosphorylation modulates marlin intramolecular association and binding to critical effectors important for NF2 growth suppression
-
Rong, R., Surace, E. I., Haipek, C. A., Gutmann, D. H. & Ye, K. Serine 518 phosphorylation modulates marlin intramolecular association and binding to critical effectors important for NF2 growth suppression. Oncogene 23, 8447-8454 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 8447-8454
-
-
Rong, R.1
Surace, E.I.2
Haipek, C.A.3
Gutmann, D.H.4
Ye, K.5
-
8
-
-
0032571272
-
Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli
-
Shaw, R. J., McClatchey, A. I. & Jacks, T. Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli. J. Biol. Chem. 273, 7757-7764 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 7757-7764
-
-
Shaw, R.J.1
McClatchey, A.I.2
Jacks, T.3
-
9
-
-
33746722720
-
Tumorigenic transformation by CPI-17 through inhibition at a merlin phosphatase
-
Jin, H., Sperka, T., Herrlich, P. & Morrison, H. Tumorigenic transformation by CPI-17 through inhibition at a merlin phosphatase. Nature 442, 576-579 (2006).
-
(2006)
Nature
, vol.442
, pp. 576-579
-
-
Jin, H.1
Sperka, T.2
Herrlich, P.3
Morrison, H.4
-
10
-
-
27144446343
-
Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation
-
Hu, Y. et al. Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation. EMBO J. 24, 3543-3554 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 3543-3554
-
-
Hu, Y.1
-
11
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB 'by the rictor-mTOR complex
-
Sarbassov, D. D., Guertin, D. A., Ali, S. M. & Sabatini, D. M. Phosphorylation and regulation of Akt/PKB 'by the rictor-mTOR complex. Science 307, 1098-1101 (2005).
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
12
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassav, D. D. et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell 22, 159-168 (2006).
-
(2006)
Mol. Cell
, vol.22
, pp. 159-168
-
-
Sarbassav, D.D.1
-
13
-
-
33748950810
-
Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability
-
Shiota, C., Woo, J. T., Lindner, J., Shelton, K. D. & Magnuson, M. A. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability Dev. Cell 11, 583-589 (2006).
-
(2006)
Dev. Cell
, vol.11
, pp. 583-589
-
-
Shiota, C.1
Woo, J.T.2
Lindner, J.3
Shelton, K.D.4
Magnuson, M.A.5
-
14
-
-
33751348056
-
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
-
Guertin, D. A. et al. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev. Cell 11, 859-871 (2006).
-
(2006)
Dev. Cell
, vol.11
, pp. 859-871
-
-
Guertin, D.A.1
-
15
-
-
11144229268
-
Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE.-L
-
Rong, R., Tang, X., Gutmann, D. H. & Ye, K. Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE.-L. Proc. Natl Acad. Sci. USA 101, 18200-18205 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 18200-18205
-
-
Rong, R.1
Tang, X.2
Gutmann, D.H.3
Ye, K.4
-
16
-
-
0034724536
-
Structure of the ERM protein moesin reveals the FEBM domain fold masked by an extended artin binding-tail domain
-
Pearson, M. A., Reczek, D., Bretscher, A. & Karplus, P. A. Structure of the ERM protein moesin reveals the FEBM domain fold masked by an extended artin binding-tail domain. Cell 101, 259-270 (2000).
-
(2000)
Cell
, vol.101
, pp. 259-270
-
-
Pearson, M.A.1
Reczek, D.2
Bretscher, A.3
Karplus, P.A.4
-
17
-
-
10744229026
-
Merlin neutralizes the inhibitory effect of Mdm2 on p53
-
Kim, H. et al. Merlin neutralizes the inhibitory effect of Mdm2 on p53. J. Biol. Chem. 279, 7812-7818 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7812-7818
-
-
Kim, H.1
-
18
-
-
33644527303
-
Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein
-
Lee, J. Y. et al. Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein. Oncogene 25, 1143-1152 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 1143-1152
-
-
Lee, J.Y.1
-
19
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
Zhou, B. P. et al. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nature Cell Biol. 3, 973-982 (2001).
-
(2001)
Nature Cell Biol
, vol.3
, pp. 973-982
-
-
Zhou, B.P.1
-
20
-
-
0036849331
-
PKB binding proteins. Getting in on the Akt
-
Brazil, D. P., Park, J. & Hemmings, B. A. PKB binding proteins. Getting in on the Akt. Cell 111, 293-303 (2002).
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
21
-
-
0037199912
-
Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway
-
Gautreau, A. et al. Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway. J. Biol. Chem. 277, 31279-31282 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 31279-31282
-
-
Gautreau, A.1
-
22
-
-
2442629479
-
Cyclic AMP-dependent protein kinase phosphorylates Merlin at serine 518 independently of P21-activated kinase and promotes Merlin-Ezrin heterodimerization
-
Alfthan, K., Heiska, L., Gronholm, M., Renkema, G. H. & Carpen, O. Cyclic AMP-dependent protein kinase phosphorylates Merlin at serine 518 independently of P21-activated kinase and promotes Merlin-Ezrin heterodimerization. J. Biol. Chem. (2004).
-
(2004)
J. Biol. Chem
-
-
Alfthan, K.1
Heiska, L.2
Gronholm, M.3
Renkema, G.H.4
Carpen, O.5
-
23
-
-
0031896691
-
Neurofibromatosis 2 tumour suppressor schwannomin interacts with betall-spectrin
-
Scoles, D. R. et al. Neurofibromatosis 2 tumour suppressor schwannomin interacts with betall-spectrin. Nature Genet. 18 354-359 (1998).
-
(1998)
Nature Genet
, vol.18
, pp. 354-359
-
-
Scoles, D.R.1
-
24
-
-
0035884301
-
Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is regulated by association between merlin domains
-
Neill, G.W. & Crompton, M. R. Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is regulated by association between merlin domains. Biochem. J. 358, 727-735 (2001).
-
(2001)
Biochem. J
, vol.358
, pp. 727-735
-
-
Neill, G.W.1
Crompton, M.R.2
-
25
-
-
0034808728
-
A novel isoform of beta-spectrin II localizes to cerebellar Purkinje-cell bodies and interacts with neurofibromatosis type 2 gene product schwannomin
-
Chen, Y., Yu, P., Lu, D., Tagle, D. A. & Cai, T. A novel isoform of beta-spectrin II localizes to cerebellar Purkinje-cell bodies and interacts with neurofibromatosis type 2 gene product schwannomin. J. Mol. Neurosci. 17, 59-70 (2001).
-
(2001)
J. Mol. Neurosci
, vol.17
, pp. 59-70
-
-
Chen, Y.1
Yu, P.2
Lu, D.3
Tagle, D.A.4
Cai, T.5
-
26
-
-
0035949431
-
Erythrocyte spectrin is an E2 ubiquitin conjugating enzyme
-
Kakhniashvili, D. G. et al. Erythrocyte spectrin is an E2 ubiquitin conjugating enzyme. Biochemistry 40, 11630-11642 (2001).
-
(2001)
Biochemistry
, vol.40
, pp. 11630-11642
-
-
Kakhniashvili, D.G.1
-
27
-
-
0037443055
-
Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor
-
Cichowski, K., Santiago, S., Jardim, M., Johnson, B. W. & Jacks, T. Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor. Genes Dev. 17, 449-454 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 449-454
-
-
Cichowski, K.1
Santiago, S.2
Jardim, M.3
Johnson, B.W.4
Jacks, T.5
-
28
-
-
33646759590
-
Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase
-
Ahn, J. Y. et al. Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J. 25, 2083-2095 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 2083-2095
-
-
Ahn, J.Y.1
|