Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse

Psychopharmacology

Volumn 233, Issue 18, 2016, Pages 3449-3459

  Vengeliene, Valentina ^a,b   Cannella, Nazzareno ^a   Takahashi, Tatiane ^a   Spanagel, Rainer ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Cocaine; Craving; Ethanol; Kynurenic acid; Kynurenine 3 monooxygenase; Relapse

Indexed keywords

ALCOHOL; COCAINE; DRUGS USED IN THE TREATMENT OF ADDICTION; JM 6; KYNURENINE; OXYGENASE INHIBITOR; RO 618048; UNCLASSIFIED DRUG; 2-(3,4-DIMETHOXYBENZENESULFONYLAMINO)-4-(3-NITROPHENYL)-5-(PIPERIDIN-1-YL)METHYLTHIAZOLE; CENTRAL DEPRESSANT AGENT; DOPAMINE UPTAKE INHIBITOR; KYNURENINE 3 MONOOXYGENASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RO 61-8048; SULFONAMIDE; THIAZOLE DERIVATIVE;

ALCOHOL CONSUMPTION; ALCOHOL SEEKING BEHAVIOR; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ARTICLE; COCAINE SEEKING BEHAVIOR; CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG EFFECT; DRUG MECHANISM; DRUG SEEKING BEHAVIOR; MALE; METABOLIC SHIFT; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; RELAPSE; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; DRUG SELF ADMINISTRATION; RECURRENT DISEASE; WISTAR RAT;

ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COCAINE; DOPAMINE UPTAKE INHIBITORS; DRUG-SEEKING BEHAVIOR; ETHANOL; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; MALE; METABOLIC NETWORKS AND PATHWAYS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RECURRENCE; SELF ADMINISTRATION; SULFONAMIDES; THIAZOLES;

EID: 84980009679     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-016-4384-9     Document Type: Article

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