Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking

Neuron

Volumn 59, Issue 3, 2008, Pages 497-508

  Engblom, David ^a   Bilbao, Ainhoa ^b   Sanchis Segura, Carles ^b   Dahan, Lionel ^c   Perreau Lenz, Stéphanie ^b   Balland, Bénédicte ^c   Parkitna, Jan Rodriguez ^a   Luján, Rafael ^e   Halbout, Briac ^b   Mameli, Manuel ^c   Parlato, Rosanna ^a   Sprengel, Rolf ^f   Lüscher, Christian ^c,d   Schütz, Günther ^a   Spanagel, Rainer ^b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^e UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^f MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

HUMDISEASE; PROTEINS; SYSNEURO

Indexed keywords

COCAINE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COCAINE DEPENDENCE; DOPAMINERGIC NERVE CELL; LOCOMOTION; MALE; MESENCEPHALON; MOUSE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SYNAPSE;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; DOPAMINE; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURONAL PLASTICITY; NEURONS; PATCH-CLAMP TECHNIQUES; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS; VALINE; VENTRAL TEGMENTAL AREA;

EID: 48749122087     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2008.07.010     Document Type: Article

References (47)

1. Abarca C., Albrecht U., and Spanagel R. Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc. Natl. Acad. Sci. USA 99 (2002) 9026-9030
2. Adesnik H., Li G., During M.J., Pleasure S.J., and Nicoll R.A. NMDA receptors inhibit synapse unsilencing during brain development. Proc. Natl. Acad. Sci. USA 105 (2008) 5597-5602
3. Bellone C., and Lüscher C. Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression. Nat. Neurosci. 9 (2006) 636-641
4. Borgland S.L., Malenka R.C., and Bonci A. Acute and chronic cocaine-induced potentiation of synaptic strength in the ventral tegmental area: electrophysiological and behavioral correlates in individual rats. J. Neurosci. 24 (2004) 7482-7490
5. Carlezon Jr. W.A., and Nestler E.J. Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse?. Trends Neurosci. 25 (2002) 610-615
6. Carlezon Jr. W.A., Boundy V.A., Haile C.N., Lane S.B., Kalb R.G., Neve R.L., and Nestler E.J. Sensitization to morphine induced by viral-mediated gene transfer. Science 277 (1997) 812-814
7. Churchill L., Swanson C.J., Urbina M., and Kalivas P.W. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. J. Neurochem. 72 (1999) 2397-2403
8. Di Chiara G., and Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. USA 85 (1988) 5274-5278
9. Dong Y., Saal D., Thomas M., Faust R., Bonci A., Robinson T., and Malenka R.C. Cocaine-induced potentiation of synaptic strength in dopamine neurons: behavioral correlates in GluRA(-/-) mice. Proc. Natl. Acad. Sci. USA 101 (2004) 14282-14287
10. Erdmann G., Schutz G., and Berger S. Inducible gene inactivation in neurons of the adult mouse forebrain. BMC Neurosci. 8 (2007) 63
11. Feil R., Wagner J., Metzger D., and Chambon P. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun. 237 (1997) 752-757
12. Fitzgerald L.W., Ortiz J., Hamedani A.G., and Nestler E.J. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. J. Neurosci. 16 (1996) 274-282
13. Giros B., Jaber M., Jones S.R., Wightman R.M., and Caron M.G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379 (1996) 606-612
14. Grignaschi G., Burbassi S., Zennaro E., Bendotti C., and Cervo L. A single high dose of cocaine induces behavioural sensitization and modifies mRNA encoding GluR1 and GAP-43 in rats. Eur. J. Neurosci. 20 (2004) 2833-2837
15. Hall B.J., Ripley B., and Ghosh A. NR2B signaling regulates the development of synaptic AMPA receptor current. J. Neurosci. 27 (2007) 13446-13456
16. Harris G.C., and Aston-Jones G. Critical role for ventral tegmental GLU in preference for a cocaine-conditioned environment. Neuropsychopharmacology 28 (2003) 73-76
17. Heusner C.L., and Palmiter R.D. Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference. J. Neurosci. 25 (2005) 6651-6657
18. Itzhak Y., and Martin J.L. Cocaine-induced conditioned place preference in mice: induction, extinction and reinstatement by related psychostimulants. Neuropsychopharmacology 26 (2002) 130-134
19. Kalivas P.W., and Alesdatter J.E. Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine. J. Pharmacol. Exp. Ther. 267 (1993) 486-495
20. Kauer J.A., and Malenka R.C. Synaptic plasticity and addiction. Nat. Rev. Neurosci. 8 (2007) 844-858
21. Liu Q.S., Pu L., and Poo M.M. Repeated cocaine exposure in vivo facilitates LTP induction in midbrain dopamine neurons. Nature 437 (2005) 1027-1031
22. Lu W., Monteggia L.M., and Wolf M.E. Repeated administration of amphetamine or cocaine does not alter AMPA receptor subunit expression in the rat midbrain. Neuropsychopharmacology 26 (2002) 1-13
23. Lüscher C., and Ungless M.A. The mechanistic classification of addictive drugs. PLoS Med. 3 (2006) e437 10.1371/journal.pmed.0030437
24. Lüscher C., and Bellone C. Cocaine-induced synaptic plasticity: a key to addiction. Nat. Neurosci. 11 (2008) 737-738
25. Mameli M., Balland B., Luján R., and Lüscher C. Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area. Science 317 (2007) 530-533
26. Mead A.N., Brown G., Le Merrer J., and Stephens D.N. Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice. Psychopharmacology (Berl.) 179 (2005) 164-171
27. Niewoehner B., Single F.N., Hvalby O., Jensen V., Borgloh S.M., Seeburg P.H., Rawlins J.N., Sprengel R., and Bannerman D.M. Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus. Eur. J. Neurosci. 25 (2007) 837-846
28. Parlato R., Rieker C., Turiault M., Tronche F., and Schutz G. Survival of DA neurons is independent of CREM upregulation in absence of CREB. Genesis 44 (2006) 454-464
29. Ramsey A.J., Laakso A., Cyr M., Sotnikova T.D., Salahpour A., Medvedev I.O., Dykstra L.A., Gainetdinov R.R., and Caron M.G. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology, (2008) 10.1038/sj.npp.1301663 in press. Published online January 9, 2008
30. Saal D., Dong Y., Bonci A., and Malenka R.C. Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron 37 (2003) 577-582
31. Sanchis-Segura C., and Spanagel R. Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict. Biol. 11 (2006) 2-38
32. Schmidt H.D., Anderson S.M., Famous K.R., Kumaresan V., and Pierce R.C. Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seeking. Eur. J. Pharmacol. 526 (2005) 65-76
33. Shaham Y., Shalev U., Lu L., De Wit H., and Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl.) 168 (2003) 3-20
34. Shimshek D.R., Jensen V., Celikel T., Geng Y., Schupp B., Bus T., Mack V., Marx V., Hvalby O., Seeburg P.H., and Sprengel R. Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation. J. Neurosci. 26 (2006) 8428-8440
35. Spanagel R., and Weiss F. The dopamine hypothesis of reward: past and current status. Trends Neurosci. 22 (1999) 521-527
36. Spielewoy C., Roubert C., Hamon M., Nosten-Bertrand M., Betancur C., and Giros B. Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice. Behav. Pharmacol. 11 (2000) 279-290
37. Stephens D.N., and Mead A.N. What role do GluR1 subunits play in drug abuse?. Trends Neurosci. 26 (2003) 181-182
38. Thomas M.J., Kalivas P.W., and Shaham Y. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br. J. Pharmacol. 154 (2008) 327-342
39. Turrigiano G. Homeostatic signaling: the positive side of negative feedback. Curr. Opin. Neurobiol. 17 (2007) 318-324
40. Tzschentke T.M. Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict. Biol. 12 (2007) 227-462
41. Ungless M.A., Whistler J.L., Malenka R.C., and Bonci A. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature 411 (2001) 583-587
42. Vogt M.A., Chourbaji S., Brandwein C., Dormann C., Sprengel R., and Gass P. Suitability of tamoxifen-induced mutagenesis for behavioral phenotyping. Exp. Neurol. 211 (2008) 25-33
43. Wang H., Hu Y., and Tsien J.Z. Molecular and systems mechanisms of memory consolidation and storage. Prog. Neurobiol. 79 (2006) 123-135
44. Yamaguchi T., Sheen W., and Morales M. Glutamatergic neurons are present in the rat ventral tegmental area. Eur. J. Neurosci. 25 (2007) 106-118
45. Zamanillo D., Sprengel R., Hvalby O., Jensen V., Burnashev N., Rozov A., Kaiser K.M., Koster H.J., Borchardt T., Worley P., et al. Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science 284 (1999) 1805-1811
46. Zhuang X., Masson J., Gingrich J.A., Rayport S., and Hen R. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. J. Neurosci. Methods 143 (2005) 27-32
47. Zushida K., Sakurai M., Wada K., and Sekiguchi M. Facilitation of extinction learning for contextual fear memory by PEPA: a potentiator of AMPA receptors. J. Neurosci. 27 (2007) 158-166