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Volumn 71, Issue 11, 2012, Pages 1015-1021

Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats

Author keywords

Alcoholism; chronic intermittent alcohol vapor exposure; glutamate glutamine cycle; human; neuroimaging; rat model

Indexed keywords

GLUTAMIC ACID; GLUTAMINE;

EID: 84861096333     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.07.034     Document Type: Article
Times cited : (160)

References (45)
  • 1
    • 67649985942 scopus 로고    scopus 로고
    • Alcoholism: A systems approach from molecular physiology to addictive behavior
    • R. Spanagel Alcoholism: A systems approach from molecular physiology to addictive behavior Physiol Rev 89 2009 649 705
    • (2009) Physiol Rev , vol.89 , pp. 649-705
    • Spanagel, R.1
  • 2
    • 0029119866 scopus 로고
    • Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum
    • Z.L. Rossetti, S. Carboni Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum Eur J Pharmacol 283 1995 177 183
    • (1995) Eur J Pharmacol , vol.283 , pp. 177-183
    • Rossetti, Z.L.1    Carboni, S.2
  • 3
    • 0038619059 scopus 로고    scopus 로고
    • Alcohol and withdrawal: From animal research to clinical issues
    • DOI 10.1016/S0149-7634(03)00030-7, PII S0149763403000307
    • P. De Witte, E. Pinto, M. Ansseau, P. Verbanck Alcohol and withdrawal: From animal research to clinical issues Neurosci Biobehav Rev 27 2003 189 197 (Pubitemid 36677428)
    • (2003) Neuroscience and Biobehavioral Reviews , vol.27 , Issue.3 , pp. 189-197
    • De Witte, Ph.1    Pinto, E.2    Ansseau, M.3    Verbanck, P.4
  • 4
    • 36849072543 scopus 로고    scopus 로고
    • Glutamatergic substrates of drug addiction and alcoholism
    • DOI 10.1016/j.bcp.2007.06.039, PII S0006295207004182, Addiction
    • J.T. Gass, M.F. Olive Glutamatergic substrates of drug addiction and alcoholism Biochem Pharmacol 75 2008 218 265 (Pubitemid 350235390)
    • (2008) Biochemical Pharmacology , vol.75 , Issue.1 , pp. 218-265
    • Gass, J.T.1    Olive, M.F.2
  • 6
    • 77956163875 scopus 로고    scopus 로고
    • Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development
    • K. Björk, A.C. Hansson, W.H. Sommer Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development Int Rev Neurobiol 91 2010 129 171
    • (2010) Int Rev Neurobiol , vol.91 , pp. 129-171
    • Björk, K.1    Hansson, A.C.2    Sommer, W.H.3
  • 7
    • 0036136686 scopus 로고    scopus 로고
    • Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol
    • DOI 10.1096/fj.01-0593com
    • R. Rimondini, C. Arlinde, W. Sommer, M. Heilig Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol FASEB J 16 2002 27 35 (Pubitemid 34027947)
    • (2002) FASEB Journal , vol.16 , Issue.1 , pp. 27-35
    • Rimondini, R.1    Arlinde, C.2    Sommer, W.3    Heilig, M.4
  • 8
    • 16844374405 scopus 로고    scopus 로고
    • Conceptual framework for the etiology of alcoholism: A "kindling" /stress hypothesis
    • DOI 10.1007/s00213-004-2016-2
    • G.R. Breese, D.H. Overstreet, D.J. Knapp Conceptual framework for the etiology of alcoholism: A "kindling"/stress hypothesis Psychopharmacology (Berl) 178 2005 367 380 (Pubitemid 40486977)
    • (2005) Psychopharmacology , vol.178 , Issue.4 , pp. 367-380
    • Breese, G.R.1    Overstreet, D.H.2    Knapp, D.J.3
  • 9
    • 76749117168 scopus 로고    scopus 로고
    • Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked?
    • M. Heilig, M. Egli, J.C. Crabbe, H.C. Becker Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked? Addict Biol 15 2010 169 184
    • (2010) Addict Biol , vol.15 , pp. 169-184
    • Heilig, M.1    Egli, M.2    Crabbe, J.C.3    Becker, H.C.4
  • 10
    • 57349099215 scopus 로고    scopus 로고
    • Identifying the neural circuitry of alcohol craving and relapse vulnerability
    • A. Heinz, A. Beck, S.M. Grusser, A.A. Grace, J. Wrase Identifying the neural circuitry of alcohol craving and relapse vulnerability Addict Biol 14 2009 108 118
    • (2009) Addict Biol , vol.14 , pp. 108-118
    • Heinz, A.1    Beck, A.2    Grusser, S.M.3    Grace, A.A.4    Wrase, J.5
  • 11
    • 0342546475 scopus 로고    scopus 로고
    • Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study
    • DOI 10.1016/S0006-3223(99)00159-6, PII S0006322399001596
    • D.P. Auer, B. Putz, E. Kraft, B. Lipinski, J. Schill, F. Holsboer Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study Biol Psychiatry 47 2000 305 313 (Pubitemid 30109243)
    • (2000) Biological Psychiatry , vol.47 , Issue.4 , pp. 305-313
    • Auer, D.P.1    Putz, B.2    Kraft, E.3    Lipinski, B.4    Schill, J.5    Holsboer, F.6
  • 12
    • 33846877408 scopus 로고    scopus 로고
    • Reduced prefrontal glutamate/glutamine and γ-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy
    • DOI 10.1001/archpsyc.64.2.193
    • G. Hasler, J.W. van der Veen, T. Tumonis, N. Meyers, J. Shen, W.C. Drevets Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy Arch Gen Psychiatry 64 2007 193 200 (Pubitemid 46220776)
    • (2007) Archives of General Psychiatry , vol.64 , Issue.2 , pp. 193-200
    • Hasler, G.1    Van Der Veen, J.W.2    Tumonis, T.3    Meyers, N.4    Shen, J.5    Drevets, W.C.6
  • 13
    • 79952576240 scopus 로고    scopus 로고
    • Ventromedial prefrontal spectroscopic abnormalities over the course of depression: A comparison among first episode, remitted recurrent and chronic patients
    • M.J. Portella, J. de Diego-Adelino, B. Gomez-Anson, R. Morgan-Ferrando, Y. Vives, D. Puigdemont Ventromedial prefrontal spectroscopic abnormalities over the course of depression: A comparison among first episode, remitted recurrent and chronic patients J Psychiatr Res 45 2011 427 434
    • (2011) J Psychiatr Res , vol.45 , pp. 427-434
    • Portella, M.J.1    De Diego-Adelino, J.2    Gomez-Anson, B.3    Morgan-Ferrando, R.4    Vives, Y.5    Puigdemont, D.6
  • 15
    • 81055140613 scopus 로고    scopus 로고
    • Involvement of glutamate in rest-stimulus interaction between perigenual and supragenual anterior cingulate cortex: A combined fMRI-MRS study
    • [published online ahead of print February 8]
    • N.W. Duncan, B. Enzi, C. Wiebking, G. Northoff Involvement of glutamate in rest-stimulus interaction between perigenual and supragenual anterior cingulate cortex: A combined fMRI-MRS study [published online ahead of print February 8] Hum Brain Mapp 2011
    • (2011) Hum Brain Mapp
    • Duncan, N.W.1    Enzi, B.2    Wiebking, C.3    Northoff, G.4
  • 16
    • 77956381514 scopus 로고    scopus 로고
    • Correlation of glutamate levels in the anterior cingulate cortex with self-reported impulsivity in patients with borderline personality disorder and healthy controls
    • M. Hoerst, W. Weber-Fahr, N. Tunc-Skarka, M. Ruf, M. Bohus, C. Schmahl, G. Ende Correlation of glutamate levels in the anterior cingulate cortex with self-reported impulsivity in patients with borderline personality disorder and healthy controls Arch Gen Psychiatry 67 2010 946 954
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 946-954
    • Hoerst, M.1    Weber-Fahr, W.2    Tunc-Skarka, N.3    Ruf, M.4    Bohus, M.5    Schmahl, C.6    Ende, G.7
  • 17
    • 77951619603 scopus 로고    scopus 로고
    • Increased activation of the ACC during a spatial working memory task in alcohol-dependence versus heavy social drinking
    • S. Vollstadt-Klein, D. Hermann, J. Rabinstein, S. Wichert, O. Klein, G. Ende, K. Mann Increased activation of the ACC during a spatial working memory task in alcohol-dependence versus heavy social drinking Alcohol Clin Exp Res 34 2010 771 776
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 771-776
    • Vollstadt-Klein, S.1    Hermann, D.2    Rabinstein, J.3    Wichert, S.4    Klein, O.5    Ende, G.6    Mann, K.7
  • 18
    • 84861095342 scopus 로고    scopus 로고
    • MR spectroscopy in opiate maintenance therapy: Association of glutamate with the number of previous withdrawals in the anterior cingulate cortex
    • [published online ahead of print February 11]
    • D. Hermann, U. Frischknecht, M. Heinrich, M. Hoerst, C. Vollmert, S. Vollstadt-Klein MR spectroscopy in opiate maintenance therapy: Association of glutamate with the number of previous withdrawals in the anterior cingulate cortex [published online ahead of print February 11] Addict Biol 2011
    • (2011) Addict Biol
    • Hermann, D.1    Frischknecht, U.2    Heinrich, M.3    Hoerst, M.4    Vollmert, C.5    Vollstadt-Klein, S.6
  • 19
    • 0024417684 scopus 로고
    • Assessment of alcohol withdrawal: The revised Clinical Institute Withdrawal Assessment for Alcohol scale (CIWA-Ar)
    • J.T. Sullivan, K. Sykora, J. Schneiderman, C.A. Naranjo, E.M. Sellers Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar) Br J Addict 84 1989 1353 1357 (Pubitemid 19281139)
    • (1989) British Journal of Addiction , vol.84 , Issue.11 , pp. 1353-1357
    • Sullivan, J.T.1    Sykora, K.2    Schneiderman, J.3    Naranjo, C.A.4    Sellers, E.M.5
  • 20
    • 1842504496 scopus 로고    scopus 로고
    • Glutamate concentrations in human brain using single voxel proton magnetic resonance spectroscopy at 3 Tesla
    • DOI 10.1016/j.neuroimage.2003.11.014, PII S1053811903007353
    • F. Schubert, J. Gallinat, F. Seifert, H. Rinneberg Glutamate concentrations in human brain using single voxel proton magnetic resonance spectroscopy at 3 Tesla Neuroimage 21 2004 1762 1771 (Pubitemid 38446596)
    • (2004) NeuroImage , vol.21 , Issue.4 , pp. 1762-1771
    • Schubert, F.1    Gallinat, J.2    Seifert, F.3    Rinneberg, H.4
  • 21
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • DOI 10.1002/mrm.1910300604
    • S.W. Provencher Estimation of metabolite concentrations from localized in vivo proton NMR spectra Magn Reson Med 30 1993 672 679 (Pubitemid 23360802)
    • (1993) Magnetic Resonance in Medicine , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 22
    • 37349041024 scopus 로고    scopus 로고
    • Upregulation of Voluntary Alcohol Intake, Behavioral Sensitivity to Stress, and Amygdala Crhr1 Expression Following a History of Dependence
    • DOI 10.1016/j.biopsych.2007.01.010, PII S0006322307000704
    • W.H. Sommer, R. Rimondini, A.C. Hansson, P.A. Hipskind, D.R. Gehlert, C.S. Barr, M. Heilig Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala Crhr1 expression following a history of dependence Biol Psychiatry 63 2008 139 145 (Pubitemid 350299311)
    • (2008) Biological Psychiatry , vol.63 , Issue.2 , pp. 139-145
    • Sommer, W.H.1    Rimondini, R.2    Hansson, A.C.3    Hipskind, P.A.4    Gehlert, D.R.5    Barr, C.S.6    Heilig, M.A.7
  • 23
    • 78650273136 scopus 로고    scopus 로고
    • Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues
    • M. Heilig, A. Thorsell, W.H. Sommer, A.C. Hansson, V.A. Ramchandani, D.T. George Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues Neurosci Biobehav Rev 35 2010 332 344
    • (2010) Neurosci Biobehav Rev , vol.35 , pp. 332-344
    • Heilig, M.1    Thorsell, A.2    Sommer, W.H.3    Hansson, A.C.4    Ramchandani, V.A.5    George, D.T.6
  • 24
    • 70350302198 scopus 로고    scopus 로고
    • Biochemistry and anatomy of transmitter glutamate
    • O.P. Ottersen, J. Storm-Mathisen, Elsevier Amsterdam
    • J. Broman, B. Hassel, E. Rinvik, O.P. Ottersen Biochemistry and anatomy of transmitter glutamate O.P. Ottersen, J. Storm-Mathisen, Glutamate 2000 Elsevier Amsterdam 1 44
    • (2000) Glutamate , pp. 1-44
    • Broman, J.1    Hassel, B.2    Rinvik, E.3    Ottersen, O.P.4
  • 26
    • 77957690685 scopus 로고    scopus 로고
    • Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: A randomized controlled experimental medicine study
    • J.C. Umhau, R. Momenan, M.L. Schwandt, E. Singley, M. Lifshitz, L. Doty Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: A randomized controlled experimental medicine study Arch Gen Psychiatry 67 2010 1069 1077
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 1069-1077
    • Umhau, J.C.1    Momenan, R.2    Schwandt, M.L.3    Singley, E.4    Lifshitz, M.5    Doty, L.6
  • 27
    • 0031763827 scopus 로고    scopus 로고
    • Synthesis of glutamate and its regulation
    • E. Kvamme Synthesis of glutamate and its regulation Prog Brain Res 116 1998 73 85 (Pubitemid 28526929)
    • (1998) Progress in Brain Research , vol.116 , pp. 73-85
    • Kvamme, E.1
  • 28
    • 0038650885 scopus 로고    scopus 로고
    • In vivo NMR Studies of the Glutamate Neurotransmitter Flux and Neuroenergetics: Implications for Brain Function
    • DOI 10.1146/annurev.physiol.65.092101.142131
    • D.L. Rothman, K.L. Behar, F. Hyder, R.G. Shulman In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: Implications for brain function Annu Rev Physiol 65 2003 401 427 (Pubitemid 38249161)
    • (2003) Annual Review of Physiology , vol.65 , pp. 401-427
    • Rothman, D.L.1    Behar, K.L.2    Hyder, F.3    Shulman, R.G.4
  • 29
    • 0346888682 scopus 로고    scopus 로고
    • 13C-NMR
    • C. Zwingmann, D. Leibfritz Regulation of glial metabolism studied by 13C-NMR NMR Biomed 16 2003 370 399 (Pubitemid 38008364)
    • (2003) NMR in Biomedicine , vol.16 , Issue.6-7 , pp. 370-399
    • Zwingmann, C.1    Leibfritz, D.2
  • 30
    • 0026544324 scopus 로고
    • Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
    • O.P. Ottersen, N. Zhang, F. Walberg Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum Neuroscience 46 1992 519 534
    • (1992) Neuroscience , vol.46 , pp. 519-534
    • Ottersen, O.P.1    Zhang, N.2    Walberg, F.3
  • 31
    • 33750481898 scopus 로고    scopus 로고
    • The glutamate-glutamine cycle as an inducible, protective face of macrophage activation
    • DOI 10.1189/jlb.0306153
    • G. Gras, F. Porcheray, B. Samah, C. Leone The glutamate-glutamine cycle as an inducible, protective face of macrophage activation J Leukoc Biol 80 2006 1067 1075 (Pubitemid 44646312)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.5 , pp. 1067-1075
    • Gras, G.1    Porcheray, F.2    Samah, B.3    Leone, C.4
  • 33
    • 62449319441 scopus 로고    scopus 로고
    • Counting the number of releasable synaptic vesicles in a presynaptic terminal
    • K. Ikeda, J.M. Bekkers Counting the number of releasable synaptic vesicles in a presynaptic terminal Proc Natl Acad Sci U S A 106 2009 2945 2950
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2945-2950
    • Ikeda, K.1    Bekkers, J.M.2
  • 34
    • 65649143541 scopus 로고    scopus 로고
    • Synapse-to-synapse variation in mean synaptic vesicle size and its relationship with synaptic morphology and function
    • L. Qu, Y. Akbergenova, Y. Hu, T. Schikorski Synapse-to-synapse variation in mean synaptic vesicle size and its relationship with synaptic morphology and function J Comp Neurol 514 2009 343 352
    • (2009) J Comp Neurol , vol.514 , pp. 343-352
    • Qu, L.1    Akbergenova, Y.2    Hu, Y.3    Schikorski, T.4
  • 35
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • P.W. Kalivas The glutamate homeostasis hypothesis of addiction Nat Rev Neurosci 10 2009 561 572
    • (2009) Nat Rev Neurosci , vol.10 , pp. 561-572
    • Kalivas, P.W.1
  • 36
    • 64949163211 scopus 로고    scopus 로고
    • In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage
    • N.M. Zahr, D. Mayer, S. Vinco, J. Orduna, R. Luong, E.V. Sullivan, A. Pfefferbaum In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage Neuropsychopharmacology 34 2009 1427 1442
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1427-1442
    • Zahr, N.M.1    Mayer, D.2    Vinco, S.3    Orduna, J.4    Luong, R.5    Sullivan, E.V.6    Pfefferbaum, A.7
  • 37
    • 77950369644 scopus 로고    scopus 로고
    • Brain injury and recovery following binge ethanol: Evidence from in vivo magnetic resonance spectroscopy
    • N.M. Zahr, D. Mayer, T. Rohlfing, M.P. Hasak, O. Hsu, S. Vinco Brain injury and recovery following binge ethanol: Evidence from in vivo magnetic resonance spectroscopy Biol Psychiatry 67 2010 846 854
    • (2010) Biol Psychiatry , vol.67 , pp. 846-854
    • Zahr, N.M.1    Mayer, D.2    Rohlfing, T.3    Hasak, M.P.4    Hsu, O.5    Vinco, S.6
  • 38
    • 84925315114 scopus 로고    scopus 로고
    • Chronic alcohol consumption, abstinence and relapse: Brain proton magnetic resonance spectroscopy studies in animals and humans
    • W.H. Sommer, R. Spanagel, Springer New York
    • D.J. Meyerhoff, T.C. Durazzo, G. Ende Chronic alcohol consumption, abstinence and relapse: Brain proton magnetic resonance spectroscopy studies in animals and humans W.H. Sommer, R. Spanagel, Behavioral Neurobiology of Alcohol Addiction 2010 Springer New York
    • (2010) Behavioral Neurobiology of Alcohol Addiction
    • Meyerhoff, D.J.1    Durazzo, T.C.2    Ende, G.3
  • 39
    • 78649470803 scopus 로고    scopus 로고
    • An integrated genome research network for studying the genetics of alcohol addiction
    • R. Spanagel, D. Bartsch, B. Brors, N. Dahmen, J. Deussing, R. Eils An integrated genome research network for studying the genetics of alcohol addiction Addict Biol 15 2010 369 379
    • (2010) Addict Biol , vol.15 , pp. 369-379
    • Spanagel, R.1    Bartsch, D.2    Brors, B.3    Dahmen, N.4    Deussing, J.5    Eils, R.6
  • 40
    • 0020144613 scopus 로고
    • Alcohol dependence syndrome: M0000easurement and validation
    • H.A. Skinner, B.A. Allen Alcohol dependence syndrome: M0000easurement and validation J Abnorm Psychol 91 1982 199 209
    • (1982) J Abnorm Psychol , vol.91 , pp. 199-209
    • Skinner, H.A.1    Allen, B.A.2
  • 41
    • 0027154845 scopus 로고
    • Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption II
    • J.B. Saunders, O.G. Aasland, T.F. Babor, J.R. Delafuente, M. Grant Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption - II Addiction 88 1993 791 804 (Pubitemid 23194530)
    • (1993) Addiction , vol.88 , Issue.6 , pp. 791-804
    • Saunders, J.B.1    Aasland, O.G.2    Babor, T.F.3    De La Fuente, J.R.4    Grant, M.5
  • 43
    • 0025923219 scopus 로고
    • The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerstrom Tolerance Questionnaire
    • T.F. Heatherton, L.T. Kozlowski, R.C. Frecker, K.O. Fagerstrom The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerstrom Tolerance Questionnaire Br J Addict 86 1991 1119 1127
    • (1991) Br J Addict , vol.86 , pp. 1119-1127
    • Heatherton, T.F.1    Kozlowski, L.T.2    Frecker, R.C.3    Fagerstrom, K.O.4
  • 44
    • 0034080504 scopus 로고    scopus 로고
    • Die OCDS-G: Psychomaterische kennwerte der Deutschen version der Obsessive Compulsive Drinking Scale
    • K. Mann, K. Ackermann The OCDS-G: Psychometric Characteristics of the German Version of the Obsessive Drinking Scale Sucht 46 2000 90 100 (Pubitemid 30387287)
    • (2000) Sucht , vol.46 , Issue.2 , pp. 90-100
    • Mann, K.1    Ackermann, K.2


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