메뉴 건너뛰기




Volumn 115, Issue 8, 2008, Pages 1087-1091

The Janus-face kynurenic acid

Author keywords

Electrophysiology; Hippocampus; Kynurenic acid; NMDA receptor

Indexed keywords

JANUS KINASE; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; TRYPTOPHAN;

EID: 49749101159     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-008-0052-5     Document Type: Article
Times cited : (103)

References (39)
  • 1
    • 2442714056 scopus 로고    scopus 로고
    • Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus
    • M Alkondon EF Pereira P Yu EZ Arruda LE Almeida P Guidetti 2004 Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus J. Neurosci 24 4635 4648
    • (2004) J. Neurosci , vol.24 , pp. 4635-4648
    • Alkondon, M.1    Pereira, E.F.2    Yu, P.3    Arruda, E.Z.4    Almeida, L.E.5    Guidetti, P.6
  • 2
    • 0033058001 scopus 로고    scopus 로고
    • Kynurenine metabolism in Alzheimer's disease
    • 2
    • H Baran K Jellinger L Deecke 1999 Kynurenine metabolism in Alzheimer's disease J Neural Transm 106 2 165 181
    • (1999) J Neural Transm , vol.106 , pp. 165-181
    • Baran, H.1    Jellinger, K.2    Deecke, L.3
  • 3
    • 0025161567 scopus 로고
    • Kynurenine pathway measurements in Huntington's disease striatum: Evidence for reduced formation of kynurenic acid
    • 4
    • MF Beal WR Matson KJ Swartz PH Gamache ED Bird 1990 Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid J Neurochem 55 4 1327 1339
    • (1990) J Neurochem , vol.55 , pp. 1327-1339
    • Beal, M.F.1    Matson, W.R.2    Swartz, K.J.3    Gamache, P.H.4    Bird, E.D.5
  • 4
    • 0036734822 scopus 로고    scopus 로고
    • Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures
    • 6
    • R Carpenedo E Meli F Peruginelli DE Pellegrini-Giampietro F Moroni 2002 Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures J Neurochem 82 6 1465 1471
    • (2002) J Neurochem , vol.82 , pp. 1465-1471
    • Carpenedo, R.1    Meli, E.2    Peruginelli, F.3    Pellegrini-Giampietro, D.E.4    Moroni, F.5
  • 7
    • 34250625265 scopus 로고    scopus 로고
    • Neuroprotective effect of l-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils
    • 1-3
    • G Gigler G Szenasi A Simo G Levay LG Harsing Jr K Sas L Vecsei J Toldi 2007 Neuroprotective effect of l-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils Eur J Pharmacol 564 1-3 116 122
    • (2007) Eur J Pharmacol , vol.564 , pp. 116-122
    • Gigler, G.1    Szenasi, G.2    Simo, A.3    Levay, G.4    Harsing Jr., L.G.5    Sas, K.6    Vecsei, L.7    Toldi, J.8
  • 8
    • 0037449906 scopus 로고    scopus 로고
    • Electrochemical and in vitro evaluation of the redox-properties of kynurenine species
    • 3
    • GI Giles CA Collins TW Stone C Jacob 2003 Electrochemical and in vitro evaluation of the redox-properties of kynurenine species Biochem Biophys Res Commun 300 3 719 724
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 719-724
    • Giles, G.I.1    Collins, C.A.2    Stone, T.W.3    Jacob, C.4
  • 9
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: Physiopathological implications
    • 19
    • C Hilmas EF Pereira M Alkondon A Rassoulpour R Schwarcz EX Albuquerque 2001 The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications J Neurosci 21 19 7463 7473
    • (2001) J Neurosci , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 10
    • 18344408121 scopus 로고    scopus 로고
    • Deficit of endogenous kynurenic acid in the frontal cortex of rats with a genetic form of absence epilepsy
    • 5
    • RM Kaminski E Zielinska A Dekundy G van Luijtelaar W Turski 2003 Deficit of endogenous kynurenic acid in the frontal cortex of rats with a genetic form of absence epilepsy Pol J Pharmacol 55 5 741 746
    • (2003) Pol J Pharmacol , vol.55 , pp. 741-746
    • Kaminski, R.M.1    Zielinska, E.2    Dekundy, A.3    Van Luijtelaar, G.4    Turski, W.5
  • 11
    • 0024564076 scopus 로고
    • A glycine site associated with N-methyl-d-aspartic acid receptors: Characterization and identification of a new class of antagonists
    • 4
    • M Kessler T Terramani G Lynch M Baudry 1989 A glycine site associated with N-methyl-d-aspartic acid receptors: characterization and identification of a new class of antagonists J Neurochem 52 4 1319 1328
    • (1989) J Neurochem , vol.52 , pp. 1319-1328
    • Kessler, M.1    Terramani, T.2    Lynch, G.3    Baudry, M.4
  • 12
    • 1342300601 scopus 로고    scopus 로고
    • Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex
    • 1-2
    • C Kiss PD Shepard F Bari R Schwarcz 2004 Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex Brain Res 1002 1-2 129 135
    • (2004) Brain Res , vol.1002 , pp. 129-135
    • Kiss, C.1    Shepard, P.D.2    Bari, F.3    Schwarcz, R.4
  • 13
    • 0347024127 scopus 로고    scopus 로고
    • Kynurenines in neurodegenerative disorders: Therapeutic consideration
    • P Klivenyi J Toldi L Vecsei 2004 Kynurenines in neurodegenerative disorders: therapeutic consideration Adv Exp Med Biol 541 169 183
    • (2004) Adv Exp Med Biol , vol.541 , pp. 169-183
    • Klivenyi, P.1    Toldi, J.2    Vecsei, L.3
  • 14
    • 17944399946 scopus 로고    scopus 로고
    • Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) treatment
    • 4
    • E Knyihar-Csillik B Csillik M Pakaski B Krisztin-Peva E Dobo E Okuno L Vecsei 2004 Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) treatment Neuroscience 126 4 899 914
    • (2004) Neuroscience , vol.126 , pp. 899-914
    • Knyihar-Csillik, E.1    Csillik, B.2    Pakaski, M.3    Krisztin-Peva, B.4    Dobo, E.5    Okuno, E.6    Vecsei, L.7
  • 15
    • 36849072696 scopus 로고    scopus 로고
    • N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus
    • 16
    • E Luccini V Musante E Neri M Raiteri A Pittaluga 2007 N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus J Neurosci Res 85 16 3657 3665
    • (2007) J Neurosci Res , vol.85 , pp. 3657-3665
    • Luccini, E.1    Musante, V.2    Neri, E.3    Raiteri, M.4    Pittaluga, A.5
  • 16
    • 0041529913 scopus 로고    scopus 로고
    • Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus
    • 3
    • E Luchowska P Luchowski A Sarnowska M Wielosz WA Turski EM Urbanska 2003 Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus Pol J Pharmacol 55 3 443 447
    • (2003) Pol J Pharmacol , vol.55 , pp. 443-447
    • Luchowska, E.1    Luchowski, P.2    Sarnowska, A.3    Wielosz, M.4    Turski, W.A.5    Urbanska, E.M.6
  • 17
    • 0016138218 scopus 로고
    • Kynurenine pyruvate transaminase in rat brain
    • 1
    • Y Minatogawa T Noguchi R Kido 1974 Kynurenine pyruvate transaminase in rat brain J Neurochem 23 1 271 272
    • (1974) J Neurochem , vol.23 , pp. 271-272
    • Minatogawa, Y.1    Noguchi, T.2    Kido, R.3
  • 18
    • 0033056044 scopus 로고    scopus 로고
    • Tryptophan metabolism and brain function: Focus on kynurenine and other indole metabolites
    • 1-3
    • F Moroni 1999 Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites Eur J Pharmacol 375 1-3 87 100
    • (1999) Eur J Pharmacol , vol.375 , pp. 87-100
    • Moroni, F.1
  • 21
    • 22144432194 scopus 로고    scopus 로고
    • Role of kynurenines in the central and peripheral nervous systems
    • 3
    • H Nemeth J Toldi L Vecsei 2005 Role of kynurenines in the central and peripheral nervous systems Curr Neurovasc Res 2 3 249 260
    • (2005) Curr Neurovasc Res , vol.2 , pp. 249-260
    • Nemeth, H.1    Toldi, J.2    Vecsei, L.3
  • 25
    • 0028343956 scopus 로고
    • Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase
    • 5
    • R Pellicciari B Natalini G Costantino MR Mahmoud L Mattoli BM Sadeghpour F Moroni A Chiarugi R Carpenedo 1994 Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase J Med Chem 37 5 647 655
    • (1994) J Med Chem , vol.37 , pp. 647-655
    • Pellicciari, R.1    Natalini, B.2    Costantino, G.3    Mahmoud, M.R.4    Mattoli, L.5    Sadeghpour, B.M.6    Moroni, F.7    Chiarugi, A.8    Carpenedo, R.9
  • 26
    • 33646780229 scopus 로고    scopus 로고
    • Kynurenic acid has a dual action on AMPA receptor responses
    • 1-2
    • C Prescott AM Weeks KJ Staley KM Partin 2006 Kynurenic acid has a dual action on AMPA receptor responses Neurosci Lett 402 1-2 108 112
    • (2006) Neurosci Lett , vol.402 , pp. 108-112
    • Prescott, C.1    Weeks, A.M.2    Staley, K.J.3    Partin, K.M.4
  • 27
    • 18844388707 scopus 로고    scopus 로고
    • Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus
    • 1-2
    • H Robotka H Nemeth C Somlai L Vecsei J Toldi 2005 Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus Eur J Pharmacol 513 1-2 75 80
    • (2005) Eur J Pharmacol , vol.513 , pp. 75-80
    • Robotka, H.1    Nemeth, H.2    Somlai, C.3    Vecsei, L.4    Toldi, J.5
  • 28
    • 0036784518 scopus 로고    scopus 로고
    • Manipulation of brain kynurenines: Glial targets, neuronal effects, and clinical opportunities
    • 1
    • R Schwarcz R Pellicciari 2002 Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities J Pharmacol Exp Ther 303 1 1 10
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 1-10
    • Schwarcz, R.1    Pellicciari, R.2
  • 31
    • 0027132491 scopus 로고
    • Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury
    • 12
    • DH Smith K Okiyama MJ Thomas TK McIntosh 1993 Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury J Neurosci 13 12 5383 5392
    • (1993) J Neurosci , vol.13 , pp. 5383-5392
    • Smith, D.H.1    Okiyama, K.2    Thomas, M.J.3    McIntosh, T.K.4
  • 32
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • 3
    • TW Stone 1993 Neuropharmacology of quinolinic and kynurenic acids Pharmacol Rev 45 3 309 379
    • (1993) Pharmacol Rev , vol.45 , pp. 309-379
    • Stone, T.W.1
  • 33
    • 0035066870 scopus 로고    scopus 로고
    • Kynurenic acid antagonists and kynurenine pathway inhibitors
    • 4
    • TW Stone 2001 Kynurenic acid antagonists and kynurenine pathway inhibitors Expert Opin Investig Drugs 10 4 633 645
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 633-645
    • Stone, T.W.1
  • 34
    • 0025482465 scopus 로고
    • Cerebral synthesis and release of kynurenic acid: An endogenous antagonist of excitatory amino acid receptors
    • 9
    • KJ Swartz MJ During A Freese MF Beal 1990 Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors J Neurosci 10 9 2965 2973
    • (1990) J Neurosci , vol.10 , pp. 2965-2973
    • Swartz, K.J.1    During, M.J.2    Freese, A.3    Beal, M.F.4
  • 35
    • 0342592253 scopus 로고    scopus 로고
    • Huntington's disease, behavioral disturbances, and kynurenines: Preclinical findings and therapeutic perspectives
    • 12
    • L Vecsei MF Beal 1996 Huntington's disease, behavioral disturbances, and kynurenines: preclinical findings and therapeutic perspectives Biol Psychiatry 39 12 1061 1063
    • (1996) Biol Psychiatry , vol.39 , pp. 1061-1063
    • Vecsei, L.1    Beal, M.F.2
  • 37
    • 0016367590 scopus 로고
    • Studies on tryptophan metabolism in man
    • H Wolf 1974 Studies on tryptophan metabolism in man Scan J Clin Lab Invest 136S 1 186
    • (1974) Scan J Clin Lab Invest , vol.136 , pp. 1-186
    • Wolf, H.1
  • 39
    • 0028783959 scopus 로고
    • Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children
    • 5
    • H Yamamoto H Murakami K Horiguchi B Egawa 1995 Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children Brain Dev 17 5 327 329
    • (1995) Brain Dev , vol.17 , pp. 327-329
    • Yamamoto, H.1    Murakami, H.2    Horiguchi, K.3    Egawa, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.