New insights into the regulation by RUNX1 and GFI1(s) proteins of the endothelial to hematopoietic transition generating primordial hematopoietic cells

Cell Cycle

Volumn 15, Issue 16, 2016, Pages 2108-2114

  Thambyrajah, Roshana ^a   Patel, Rahima ^a   Mazan, Milena ^a,b   Lie a Ling, Michael ^a   Lilly, Andrew ^a   Eliades, Alexia ^a   Menegatti, Sara ^a   Garcia Alegria, Eva ^a   Florkowska, Magdalena ^a,c   Batta, Kiran ^a   Kouskoff, Valerie ^a   Lacaud, Georges ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c Adaptimmune Ltd   (United Kingdom)

Author keywords

development; EHT (endothelial to hematopoietic transition); ES cells; GFI1; GFI1B; hematopoiesis; hemogenic endothelium; HSCs (Hematopoietic stem cells); reprogramming; RUNX1

Indexed keywords

CD31 ANTIGEN; GROWTH FACTOR INDEPENDENCE 1 PROTEIN; GROWTH FACTOR INDEPENDENCE 1B PROTEIN; REGULATOR PROTEIN; STEM CELL FACTOR; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; ZINC FINGER PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; AORTA; CELL TRANSFORMATION; ENDOTHELIAL TO HEMATOPOIETIC TRANSITION; ENDOTHELIUM CELL; HEMANGIOBLAST; HEMATOPOIETIC CELL; IN VIVO STUDY; MOUSE; NONHUMAN; NOTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; YOLK SAC; ANIMAL; BIOLOGICAL MODEL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; METABOLISM;

ANIMALS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; HEMANGIOBLASTS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MODELS, BIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 84979995627     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2016.1203491     Document Type: Note

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