RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

EMBO Journal

Volumn 31, Issue 22, 2012, Pages 4318-4333

  Lichtinger, Monika ^a,g   Ingram, Richard ^a   Hannah, Rebecca ^b   Müller, Dorothee ^a   Clarke, Deborah ^a   Assi, Salam A ^c   Lie A Ling, Michael ^d   Noailles, Laura ^a,g   Vijayabaskar, M S ^c   Wu, Mengchu ^e   Tenen, Daniel G ^e,f   Westhead, David R ^c   Kouskoff, Valerie ^d   Lacaud, Georges ^d   Göttgens, Berthold ^b   Bonifer, Constanze ^a,g  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b Cambridge Institute of Molecular Medicine   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e HARVARD STEM CELL INSTITUTE   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Cell fate decisions; endothelial haematopoietic transition; haematopoiesis; RUNX1; transcriptional programming of chromatin

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CIS ACTING ELEMENT; HISTONE H3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FLI1; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL SHAPE; CONTROLLED STUDY; EPIGENETICS; GENE CONTROL; GENE INTERACTION; GENE TARGETING; GENOME ANALYSIS; HEMANGIOBLAST; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HISTONE ACETYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; BASE SEQUENCE; CELL LINE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; EMBRYONIC STEM CELLS; EPIGENESIS, GENETIC; HEMATOPOIESIS; HISTONES; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 84869232815     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.275     Document Type: Article

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