-
1
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary, C., Kumar, C., Gnad, F., Nielsen, M.L., Rehman, M., Walther, T.C., Olsen, J.V. and Mann, M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-840
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
Olsen, J.V.7
Mann, M.8
-
2
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis
-
Allfrey, V.G., Faulkner, R. and Mirsky, A.E. (1964) Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc. Natl. Acad. Sci. U.S.A. 51, 786-794
-
(1964)
Proc. Natl. Acad. Sci. U.S.A.
, vol.51
, pp. 786-794
-
-
Allfrey, V.G.1
Faulkner, R.2
Mirsky, A.E.3
-
3
-
-
39749127166
-
The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men
-
Yang, X.J. and Seto, E. (2008) The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat. Rev. Mol. Cell Biol. 9, 206-218
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 206-218
-
-
Yang, X.J.1
Seto, E.2
-
4
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
Haberland, M., Montgomery, R.L. and Olson, E.N. (2009) The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet. 10, 32-42
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
5
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel, T., Deng, C.X. and Mostoslavsky, R. (2009) Recent progress in the biology and physiology of sirtuins. Nature 460, 587-591
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
6
-
-
34247174068
-
Factors affecting the substrate specificity of histone deacetylases
-
Riester, D., Hildmann, C., Grunewald, S., Beckers, T. and Schwienhorst, A. (2007) Factors affecting the substrate specificity of histone deacetylases. Biochem. Biophys. Res. Commun. 357, 439-445
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 439-445
-
-
Riester, D.1
Hildmann, C.2
Grunewald, S.3
Beckers, T.4
Schwienhorst, A.5
-
7
-
-
33846025127
-
Dynamic regulation of histone lysine methylation by demethylases
-
Shi, Y. and Whetstine, J.R. (2007) Dynamic regulation of histone lysine methylation by demethylases. Mol. Cell 25, 1-14
-
(2007)
Mol. Cell
, vol.25
, pp. 1-14
-
-
Shi, Y.1
Whetstine, J.R.2
-
8
-
-
0029856225
-
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription
-
Rundlett, S.E., Carmen, A.A., Kobayashi, R., Bavykin, S., Turner, B.M. and Grunstein, M. (1996) HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. U.S.A. 93, 14503-14508
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 14503-14508
-
-
Rundlett, S.E.1
Carmen, A.A.2
Kobayashi, R.3
Bavykin, S.4
Turner, B.M.5
Grunstein, M.6
-
9
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
Taunton, J., Hassig, C.A. and Schreiber, S.L. (1996) A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272, 408-411
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
10
-
-
0029850458
-
Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
-
Yang, W.M., Inouye, C., Zeng, Y., Bearss, D. and Seto, E. (1996) Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc. Natl. Acad. Sci. U.S.A. 93, 12845-12850
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 12845-12850
-
-
Yang, W.M.1
Inouye, C.2
Zeng, Y.3
Bearss, D.4
Seto, E.5
-
11
-
-
0024003456
-
A direct link between core histone acetylation and transcriptionally active chromatin
-
Hebbes, T.R., Thorne, A.W. and Crane-Robinson, C. (1988) A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J. 7, 1395-1402
-
(1988)
EMBO J.
, vol.7
, pp. 1395-1402
-
-
Hebbes, T.R.1
Thorne, A.W.2
Crane-Robinson, C.3
-
12
-
-
0025217826
-
Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin
-
Ridsdale, J.A., Hendzel, M.J., Delcuve, G.P. and Davie, J.R. (1990) Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin. J. Biol. Chem. 265, 5150-5156
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 5150-5156
-
-
Ridsdale, J.A.1
Hendzel, M.J.2
Delcuve, G.P.3
Davie, J.R.4
-
13
-
-
0033519641
-
Structure and ligand of a histone acetyltransferase bromodomain
-
Dhalluin, C., Carlson, J.E., Zeng, L., He, C., Aggarwal, A.K. and Zhou, M.M. (1999) Structure and ligand of a histone acetyltransferase bromodomain. Nature 399, 491-496
-
(1999)
Nature
, vol.399
, pp. 491-496
-
-
Dhalluin, C.1
Carlson, J.E.2
Zeng, L.3
He, C.4
Aggarwal, A.K.5
Zhou, M.M.6
-
14
-
-
0033601106
-
Sin meets NuRD and other tails of repression
-
Knoepfler, P.S. and Eisenman, R.N. (1999) Sin meets NuRD and other tails of repression. Cell 99, 447-450
-
(1999)
Cell
, vol.99
, pp. 447-450
-
-
Knoepfler, P.S.1
Eisenman, R.N.2
-
15
-
-
34547684065
-
HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination
-
Boyault, C., Sadoul, K., Pabion, M. and Khochbin, S. (2007) HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination. Oncogene 26, 5468-5476
-
(2007)
Oncogene
, vol.26
, pp. 5468-5476
-
-
Boyault, C.1
Sadoul, K.2
Pabion, M.3
Khochbin, S.4
-
16
-
-
36849004821
-
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases
-
Lahm, A., Paolini, C., Pallaoro, M., Nardi, M.C., Jones, P., Neddermann, P., Sambucini, S., Bottomley, M.J., Lo Surdo, P., Carfi, A. et al. (2007) Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proc. Natl. Acad. Sci. U.S.A. 104, 17335-17340
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 17335-17340
-
-
Lahm, A.1
Paolini, C.2
Pallaoro, M.3
Nardi, M.C.4
Jones, P.5
Neddermann, P.6
Sambucini, S.7
Bottomley, M.J.8
Lo Surdo, P.9
Carfi, A.10
-
17
-
-
84874399937
-
Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice
-
Dovey, O.M., Foster, C.T., Conte, N., Edwards, S.A., Edwards, J.M., Singh, R., Vassiliou, G., Bradley, A. and Cowley, S.M. (2013) Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice. Blood 121, 1335-1344
-
(2013)
Blood
, vol.121
, pp. 1335-1344
-
-
Dovey, O.M.1
Foster, C.T.2
Conte, N.3
Edwards, S.A.4
Edwards, J.M.5
Singh, R.6
Vassiliou, G.7
Bradley, A.8
Cowley, S.M.9
-
18
-
-
0033180082
-
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
-
Zhang, Y., Ng, H.H., Erdjument-Bromage, H., Tempst, P., Bird, A. and Reinberg, D. (1999) Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev. 13, 1924-1935
-
(1999)
Genes Dev.
, vol.13
, pp. 1924-1935
-
-
Zhang, Y.1
Ng, H.H.2
Erdjument-Bromage, H.3
Tempst, P.4
Bird, A.5
Reinberg, D.6
-
19
-
-
0030969516
-
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
-
Laherty, C.D., Yang, W.M., Sun, J.M., Davie, J.R., Seto, E. and Eisenman, R.N. (1997) Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89, 349-356
-
(1997)
Cell
, vol.89
, pp. 349-356
-
-
Laherty, C.D.1
Yang, W.M.2
Sun, J.M.3
Davie, J.R.4
Seto, E.5
Eisenman, R.N.6
-
20
-
-
22344435137
-
The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development
-
Cowley, S.M., Iritani, B.M., Mendrysa, S.M., Xu, T., Cheng, P.F., Yada, J., Liggitt, H.D. and Eisenman, R.N. (2005) The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development. Mol. Cell. Biol. 25, 6990-7004
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6990-7004
-
-
Cowley, S.M.1
Iritani, B.M.2
Mendrysa, S.M.3
Xu, T.4
Cheng, P.F.5
Yada, J.6
Liggitt, H.D.7
Eisenman, R.N.8
-
21
-
-
0035868824
-
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
-
Hendrich, B., Guy, J., Ramsahoye, B., Wilson, V.A. and Bird, A. (2001) Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes Dev. 15, 710-723
-
(2001)
Genes Dev.
, vol.15
, pp. 710-723
-
-
Hendrich, B.1
Guy, J.2
Ramsahoye, B.3
Wilson, V.A.4
Bird, A.5
-
22
-
-
34247348215
-
Opposing LSD1 complexes function in developmental gene activation and repression programmes
-
Wang, J., Scully, K., Zhu, X., Cai, L., Zhang, J., Prefontaine, G.G., Krones, A., Ohgi, K.A., Zhu, P., Garcia-Bassets, I. et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446, 882-887
-
(2007)
Nature
, vol.446
, pp. 882-887
-
-
Wang, J.1
Scully, K.2
Zhu, X.3
Cai, L.4
Zhang, J.5
Prefontaine, G.G.6
Krones, A.7
Ohgi, K.A.8
Zhu, P.9
Garcia-Bassets, I.10
-
23
-
-
0032252209
-
NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
-
Xue, Y., Wong, J., Moreno, G.T., Young, M.K., Cote, J. and Wang, W. (1998) NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell 2, 851-861
-
(1998)
Mol. Cell
, vol.2
, pp. 851-861
-
-
Xue, Y.1
Wong, J.2
Moreno, G.T.3
Young, M.K.4
Cote, J.5
Wang, W.6
-
24
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
Lee, M.G., Wynder, C., Cooch, N. and Shiekhattar, R. (2005) An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437, 432-435
-
(2005)
Nature
, vol.437
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
Shiekhattar, R.4
-
25
-
-
0038642016
-
Identification and characterization of three new components of the mSin3A corepressor complex
-
Fleischer, T.C., Yun, U.J. and Ayer, D.E. (2003) Identification and characterization of three new components of the mSin3A corepressor complex. Mol. Cell. Biol. 23, 3456-3467
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3456-3467
-
-
Fleischer, T.C.1
Yun, U.J.2
Ayer, D.E.3
-
26
-
-
33747808580
-
Functional interplay between histone demethylase and deacetylase enzymes
-
Lee, M.G., Wynder, C., Bochar, D.A., Hakimi, M.A., Cooch, N. and Shiekhattar, R. (2006) Functional interplay between histone demethylase and deacetylase enzymes. Mol. Cell. Biol. 26, 6395-6402
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6395-6402
-
-
Lee, M.G.1
Wynder, C.2
Bochar, D.A.3
Hakimi, M.A.4
Cooch, N.5
Shiekhattar, R.6
-
27
-
-
84855984763
-
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
-
Watson, P.J., Fairall, L., Santos, G.M. and Schwabe, J.W. (2012) Structure of HDAC3 bound to co-repressor and inositol tetraphosphate. Nature 481, 335-340
-
(2012)
Nature
, vol.481
, pp. 335-340
-
-
Watson, P.J.1
Fairall, L.2
Santos, G.M.3
Schwabe, J.W.4
-
28
-
-
0036207977
-
Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex
-
Alland, L., David, G., Shen-Li, H., Potes, J., Muhle, R., Lee, H.C., Hou, Jr, H., Chen, K. and DePinho, R.A. (2002) Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex. Mol. Cell. Biol. 22, 2743-2750
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2743-2750
-
-
Alland, L.1
David, G.2
Shen-Li, H.3
Potes, J.4
Muhle, R.5
Lee, H.C.6
Hou Jr., H.7
Chen, K.8
Depinho, R.A.9
-
29
-
-
77649115437
-
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression
-
Yamaguchi, T., Cubizolles, F., Zhang, Y., Reichert, N., Kohler, H., Seiser, C. and Matthias, P. (2010) Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 24, 455-469
-
(2010)
Genes Dev.
, vol.24
, pp. 455-469
-
-
Yamaguchi, T.1
Cubizolles, F.2
Zhang, Y.3
Reichert, N.4
Kohler, H.5
Seiser, C.6
Matthias, P.7
-
30
-
-
0035917322
-
Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1
-
Taplick, J., Kurtev, V., Kroboth, K., Posch, M., Lechner, T. and Seiser, C. (2001) Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. J. Mol. Biol. 308, 27-38
-
(2001)
J. Mol. Biol.
, vol.308
, pp. 27-38
-
-
Taplick, J.1
Kurtev, V.2
Kroboth, K.3
Posch, M.4
Lechner, T.5
Seiser, C.6
-
31
-
-
41949128063
-
Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation
-
David, G., Grandinetti, K.B., Finnerty, P.M., Simpson, N., Chu, G.C. and Depinho, R.A. (2008) Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation. Proc. Natl. Acad. Sci. U.S.A. 105, 4168-4172
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 4168-4172
-
-
David, G.1
Grandinetti, K.B.2
Finnerty, P.M.3
Simpson, N.4
Chu, G.C.5
Depinho, R.A.6
-
32
-
-
27744577727
-
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription
-
Carrozza, M.J., Li, B., Florens, L., Suganuma, T., Swanson, S.K., Lee, K.K., Shia, W.J., Anderson, S., Yates, J., Washburn, M.P. and Workman, J.L. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123, 581-592
-
(2005)
Cell
, vol.123
, pp. 581-592
-
-
Carrozza, M.J.1
Li, B.2
Florens, L.3
Suganuma, T.4
Swanson, S.K.5
Lee, K.K.6
Shia, W.J.7
Anderson, S.8
Yates, J.9
Washburn, M.P.10
Workman, J.L.11
-
33
-
-
0034610367
-
Genomewide studies of histone deacetylase function in yeast
-
Bernstein, B.E., Tong, J.K. and Schreiber, S.L. (2000) Genomewide studies of histone deacetylase function in yeast. Proc. Natl. Acad. Sci. U.S.A. 97, 13708-13713
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13708-13713
-
-
Bernstein, B.E.1
Tong, J.K.2
Schreiber, S.L.3
-
34
-
-
34447511648
-
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility
-
Montgomery, R.L., Davis, C.A., Potthoff, M.J., Haberland, M., Fielitz, J., Qi, X., Hill, J.A., Richardson, J.A. and Olson, E.N. (2007) Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes Dev. 21, 1790-1802
-
(2007)
Genes Dev.
, vol.21
, pp. 1790-1802
-
-
Montgomery, R.L.1
Davis, C.A.2
Potthoff, M.J.3
Haberland, M.4
Fielitz, J.5
Qi, X.6
Hill, J.A.7
Richardson, J.A.8
Olson, E.N.9
-
35
-
-
33750324764
-
Negative and positive regulation of gene expression by mouse histone deacetylase 1
-
Zupkovitz, G., Tischler, J., Posch, M., Sadzak, I., Ramsauer, K., Egger, G., Grausenburger, R., Schweifer, N., Chiocca, S., Decker, T. and Seiser, C. (2006) Negative and positive regulation of gene expression by mouse histone deacetylase 1. Mol. Cell. Biol. 26, 7913-7928
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7913-7928
-
-
Zupkovitz, G.1
Tischler, J.2
Posch, M.3
Sadzak, I.4
Ramsauer, K.5
Egger, G.6
Grausenburger, R.7
Schweifer, N.8
Chiocca, S.9
Decker, T.10
Seiser, C.11
-
36
-
-
69449102464
-
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
-
Wang, Z., Zang, C., Cui, K., Schones, D.E., Barski, A., Peng, W. and Zhao, K. (2009) Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138, 1019-1031
-
(2009)
Cell
, vol.138
, pp. 1019-1031
-
-
Wang, Z.1
Zang, C.2
Cui, K.3
Schones, D.E.4
Barski, A.5
Peng, W.6
Zhao, K.7
-
37
-
-
84860189381
-
HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells
-
Kidder, B.L. and Palmer, S. (2012) HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells. Nucleic Acids Res. 40, 2925-2939
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2925-2939
-
-
Kidder, B.L.1
Palmer, S.2
-
38
-
-
0036649756
-
Genome-wide binding map of the histone deacetylase Rpd3 in yeast
-
Kurdistani, S.K., Robyr, D., Tavazoie, S. and Grunstein, M. (2002) Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Nat. Genet. 31, 248-254
-
(2002)
Nat. Genet.
, vol.31
, pp. 248-254
-
-
Kurdistani, S.K.1
Robyr, D.2
Tavazoie, S.3
Grunstein, M.4
-
39
-
-
2642544592
-
Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
-
Metivier, R., Penot, G., Hubner, M.R., Reid, G., Brand, H., Kos, M. and Gannon, F. (2003) Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115, 751-763
-
(2003)
Cell
, vol.115
, pp. 751-763
-
-
Metivier, R.1
Penot, G.2
Hubner, M.R.3
Reid, G.4
Brand, H.5
Kos, M.6
Gannon, F.7
-
40
-
-
77956830750
-
Emphasizing the positive: A role for histone deacetylases in transcriptional activation
-
Dovey, O.M., Foster, C.T. and Cowley, S.M. (2010) Emphasizing the positive: a role for histone deacetylases in transcriptional activation. Cell Cycle 9, 2700-2701
-
(2010)
Cell Cycle
, vol.9
, pp. 2700-2701
-
-
Dovey, O.M.1
Foster, C.T.2
Cowley, S.M.3
-
41
-
-
33644764030
-
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
-
Kaji, K., Caballero, I.M., MacLeod, R., Nichols, J., Wilson, V.A. and Hendrich, B. (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat. Cell Biol. 8, 285-292
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 285-292
-
-
Kaji, K.1
Caballero, I.M.2
MacLeod, R.3
Nichols, J.4
Wilson, V.A.5
Hendrich, B.6
-
42
-
-
84856962477
-
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
-
Whyte, W.A., Bilodeau, S., Orlando, D.A., Hoke, H.A., Frampton, G.M., Foster, C.T., Cowley, S.M. and Young, R.A. (2012) Enhancer decommissioning by LSD1 during embryonic stem cell differentiation. Nature 482, 221-225
-
(2012)
Nature
, vol.482
, pp. 221-225
-
-
Whyte, W.A.1
Bilodeau, S.2
Orlando, D.A.3
Hoke, H.A.4
Frampton, G.M.5
Foster, C.T.6
Cowley, S.M.7
Young, R.A.8
-
43
-
-
84860647928
-
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment
-
Reynolds, N., Latos, P., Hynes-Allen, A., Loos, R., Leaford, D., O'Shaughnessy, A., Mosaku, O., Signolet, J., Brennecke, P., Kalkan, T. et al. (2012) NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment. Cell Stem Cell 10, 583-594
-
(2012)
Cell Stem Cell
, vol.10
, pp. 583-594
-
-
Reynolds, N.1
Latos, P.2
Hynes-Allen, A.3
Loos, R.4
Leaford, D.5
O'Shaughnessy, A.6
Mosaku, O.7
Signolet, J.8
Brennecke, P.9
Kalkan, T.10
-
44
-
-
33646354640
-
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
-
Ropero, S., Fraga, M.F., Ballestar, E., Hamelin, R., Yamamoto, H., Boix-Chornet, M., Caballero, R., Alaminos, M., Setien, F., Paz, M.F. et al. (2006) A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat. Genet. 38, 566-569
-
(2006)
Nat. Genet.
, vol.38
, pp. 566-569
-
-
Ropero, S.1
Fraga, M.F.2
Ballestar, E.3
Hamelin, R.4
Yamamoto, H.5
Boix-Chornet, M.6
Caballero, R.7
Alaminos, M.8
Setien, F.9
Paz, M.F.10
-
45
-
-
77952348698
-
Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation
-
Dovey, O.M., Foster, C.T. and Cowley, S.M. (2010) Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 107, 8242-8247
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 8242-8247
-
-
Dovey, O.M.1
Foster, C.T.2
Cowley, S.M.3
-
46
-
-
84862777943
-
An epigenetic blockade of cognitive functions in the neurodegenerating brain
-
Graff, J., Rei, D., Guan, J.S., Wang, W.Y., Seo, J., Hennig, K.M., Nieland, T.J., Fass, D.M., Kao, P.F., Kahn, M. et al. (2012) An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483, 222-226
-
(2012)
Nature
, vol.483
, pp. 222-226
-
-
Graff, J.1
Rei, D.2
Guan, J.S.3
Wang, W.Y.4
Seo, J.5
Hennig, K.M.6
Nieland, T.J.7
Fass, D.M.8
Kao, P.F.9
Kahn, M.10
-
47
-
-
18444414332
-
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
-
Lagger, G., O'Carroll, D., Rembold, M., Khier, H., Tischler, J., Weitzer, G., Schuettengruber, B., Hauser, C., Brunmeir, R., Jenuwein, T. and Seiser, C. (2002) Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J. 21, 2672-2681
-
(2002)
EMBO J.
, vol.21
, pp. 2672-2681
-
-
Lagger, G.1
O'Carroll, D.2
Rembold, M.3
Khier, H.4
Tischler, J.5
Weitzer, G.6
Schuettengruber, B.7
Hauser, C.8
Brunmeir, R.9
Jenuwein, T.10
Seiser, C.11
-
48
-
-
77955425859
-
Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis
-
Wilting, R.H., Yanover, E., Heideman, M.R., Jacobs, H., Horner, J., van der Torre, J., DePinho, R.A. and Dannenberg, J.H. (2010) Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis. EMBO J. 29, 2586-2597
-
(2010)
EMBO J.
, vol.29
, pp. 2586-2597
-
-
Wilting, R.H.1
Yanover, E.2
Heideman, M.R.3
Jacobs, H.4
Horner, J.5
Van Der Torre, J.6
Depinho, R.A.7
Dannenberg, J.H.8
-
49
-
-
76749159433
-
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation
-
Zupkovitz, G., Grausenburger, R., Brunmeir, R., Senese, S., Tischler, J., Jurkin, J., Rembold, M., Meunier, D., Egger, G., Lagger, S. et al. (2010) The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation. Mol. Cell. Biol. 30, 1171-1181
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1171-1181
-
-
Zupkovitz, G.1
Grausenburger, R.2
Brunmeir, R.3
Senese, S.4
Tischler, J.5
Jurkin, J.6
Rembold, M.7
Meunier, D.8
Egger, G.9
Lagger, S.10
-
50
-
-
34347339526
-
Role for histone deacetylase 1 in human tumor cell proliferation
-
Senese, S., Zaragoza, K., Minardi, S., Muradore, I., Ronzoni, S., Passafaro, A., Bernard, L., Draetta, G.F., Alcalay, M., Seiser, C. and Chiocca, S. (2007) Role for histone deacetylase 1 in human tumor cell proliferation. Mol. Cell. Biol. 27, 4784-4795
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4784-4795
-
-
Senese, S.1
Zaragoza, K.2
Minardi, S.3
Muradore, I.4
Ronzoni, S.5
Passafaro, A.6
Bernard, L.7
Draetta, G.F.8
Alcalay, M.9
Seiser, C.10
Chiocca, S.11
-
51
-
-
66049146095
-
Genetic dissection of histone deacetylase requirement in tumor cells
-
Haberland, M., Johnson, A., Mokalled, M.H., Montgomery, R.L. and Olson, E.N. (2009) Genetic dissection of histone deacetylase requirement in tumor cells. Proc. Natl. Acad. Sci. U.S.A. 106, 7751-7755
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 7751-7755
-
-
Haberland, M.1
Johnson, A.2
Mokalled, M.H.3
Montgomery, R.L.4
Olson, E.N.5
-
52
-
-
67650090545
-
Histone deacetylase inhibitors: Potential in cancer therapy
-
Marks, P.A. and Xu, W.S. (2009) Histone deacetylase inhibitors: potential in cancer therapy. J. Cell. Biochem. 107, 600-608
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 600-608
-
-
Marks, P.A.1
Xu, W.S.2
-
53
-
-
0038079767
-
The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1
-
Rosato, R.R., Almenara, J.A. and Grant, S. (2003) The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1. Cancer Res. 63, 3637-3645
-
(2003)
Cancer Res.
, vol.63
, pp. 3637-3645
-
-
Rosato, R.R.1
Almenara, J.A.2
Grant, S.3
-
54
-
-
57549098807
-
The catalogue of somatic mutations in cancer (COSMIC)
-
Chapter 10, Unit 10.11
-
Forbes, S.A., Bhamra, G., Bamford, S., Dawson, E., Kok, C., Clements, J., Menzies, A., Teague, J.W., Futreal, P.A. and Stratton, M.R. (2008) The Catalogue of Somatic Mutations in Cancer (COSMIC). Curr. Protoc. Hum. Genet, Chapter 10, Unit 10.11
-
(2008)
Curr. Protoc. Hum. Genet.
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
Dawson, E.4
Kok, C.5
Clements, J.6
Menzies, A.7
Teague, J.W.8
Futreal, P.A.9
Stratton, M.R.10
-
55
-
-
1842631408
-
Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer
-
Halkidou, K., Gaughan, L., Cook, S., Leung, H.Y., Neal, D.E. and Robson, C.N. (2004) Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer. Prostate 59, 177-189
-
(2004)
Prostate
, vol.59
, pp. 177-189
-
-
Halkidou, K.1
Gaughan, L.2
Cook, S.3
Leung, H.Y.4
Neal, D.E.5
Robson, C.N.6
-
56
-
-
33749572938
-
Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
-
Hrzenjak, A., Moinfar, F., Kremser, M.L., Strohmeier, B., Staber, P.B., Zatloukal, K. and Denk, H. (2006) Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells. Mol. Cancer Ther. 5, 2203-2210
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2203-2210
-
-
Hrzenjak, A.1
Moinfar, F.2
Kremser, M.L.3
Strohmeier, B.4
Staber, P.B.5
Zatloukal, K.6
Denk, H.7
-
57
-
-
17144378591
-
Cip1/WAF1 expression, independent of histone deacetylase 1
-
Cip1/WAF1 expression, independent of histone deacetylase 1. Cell Death Differ. 12, 395-404
-
(2005)
Cell Death Differ
, vol.12
, pp. 395-404
-
-
Huang, B.H.1
Laban, M.2
Leung, C.H.3
Lee, L.4
Lee, C.K.5
Salto-Tellez, M.6
Raju, G.C.7
Hooi, S.C.8
-
58
-
-
84857428826
-
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development
-
Ma, P., Pan, H., Montgomery, R.L., Olson, E.N. and Schultz, R.M. (2012) Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proc. Natl. Acad. Sci. U.S.A. 109, E481-E489
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
-
-
Ma, P.1
Pan, H.2
Montgomery, R.L.3
Olson, E.N.4
Schultz, R.M.5
-
59
-
-
78649907734
-
Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells
-
LeBoeuf, M., Terrell, A., Trivedi, S., Sinha, S., Epstein, J.A., Olson, E.N., Morrisey, E.E. and Millar, S.E. (2010) Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev. Cell 19, 807-818
-
(2010)
Dev. Cell
, vol.19
, pp. 807-818
-
-
Leboeuf, M.1
Terrell, A.2
Trivedi, S.3
Sinha, S.4
Epstein, J.A.5
Olson, E.N.6
Morrisey, E.E.7
Millar, S.E.8
-
60
-
-
33847695362
-
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity
-
Trivedi, C.M., Luo, Y., Yin, Z., Zhang, M., Zhu, W., Wang, T., Floss, T., Goettlicher, M., Noppinger, P.R., Wurst, W. et al. (2007) Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity. Nat. Med. 13, 324-331
-
(2007)
Nat. Med.
, vol.13
, pp. 324-331
-
-
Trivedi, C.M.1
Luo, Y.2
Yin, Z.3
Zhang, M.4
Zhu, W.5
Wang, T.6
Floss, T.7
Goettlicher, M.8
Noppinger, P.R.9
Wurst, W.10
-
61
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
Guan, J.S., Haggarty, S.J., Giacometti, E., Dannenberg, J.H., Joseph, N., Gao, J., Nieland, T.J., Zhou, Y., Wang, X., Mazitschek, R. et al. (2009) HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459, 55-60
-
(2009)
Nature
, vol.459
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
Dannenberg, J.H.4
Joseph, N.5
Gao, J.6
Nieland, T.J.7
Zhou, Y.8
Wang, X.9
Mazitschek, R.10
-
62
-
-
35148885660
-
Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice
-
Zimmermann, S., Kiefer, F., Prudenziati, M., Spiller, C., Hansen, J., Floss, T., Wurst, W., Minucci, S. and Gottlicher, M. (2007) Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. Cancer Res. 67, 9047-9054
-
(2007)
Cancer Res.
, vol.67
, pp. 9047-9054
-
-
Zimmermann, S.1
Kiefer, F.2
Prudenziati, M.3
Spiller, C.4
Hansen, J.5
Floss, T.6
Wurst, W.7
Minucci, S.8
Gottlicher, M.9
-
63
-
-
67649797866
-
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin-TCF interaction
-
Ye, F., Chen, Y., Hoang, T., Montgomery, R.L., Zhao, X.H., Bu, H., Hu, T., Taketo, M.M., van Es, J.H., Clevers, H. et al. (2009) HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin-TCF interaction. Nat. Neurosci. 12, 829-838
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 829-838
-
-
Ye, F.1
Chen, Y.2
Hoang, T.3
Montgomery, R.L.4
Zhao, X.H.5
Bu, H.6
Hu, T.7
Taketo, M.M.8
Van Es, J.H.9
Clevers, H.10
-
64
-
-
79953186033
-
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination
-
Chen, Y., Wang, H., Yoon, S.O., Xu, X., Hottiger, M.O., Svaren, J., Nave, K.A., Kim, H.A., Olson, E.N. and Lu, Q.R. (2011) HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat. Neurosci. 14, 437-441
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 437-441
-
-
Chen, Y.1
Wang, H.2
Yoon, S.O.3
Xu, X.4
Hottiger, M.O.5
Svaren, J.6
Nave, K.A.7
Kim, H.A.8
Olson, E.N.9
Lu, Q.R.10
-
65
-
-
79953194397
-
HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells
-
Jacob, C., Christen, C.N., Pereira, J.A., Somandin, C., Baggiolini, A., Lotscher, P., Ozcelik, M., Tricaud, N., Meijer, D., Yamaguchi, T. et al. (2011) HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat. Neurosci. 14, 429-436
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 429-436
-
-
Jacob, C.1
Christen, C.N.2
Pereira, J.A.3
Somandin, C.4
Baggiolini, A.5
Lotscher, P.6
Ozcelik, M.7
Tricaud, N.8
Meijer, D.9
Yamaguchi, T.10
-
66
-
-
66049101024
-
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
-
Montgomery, R.L., Hsieh, J., Barbosa, A.C., Richardson, J.A. and Olson, E.N. (2009) Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc. Natl. Acad. Sci. U.S.A. 106, 7876-7881
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 7876-7881
-
-
Montgomery, R.L.1
Hsieh, J.2
Barbosa, A.C.3
Richardson, J.A.4
Olson, E.N.5
-
67
-
-
34250357227
-
Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1
-
Higashitsuji, H., Higashitsuji, H., Masuda, T., Liu, Y., Itoh, K. and Fujita, J. (2007) Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. J. Biol. Chem. 282, 13716-13725
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13716-13725
-
-
Higashitsuji, H.1
Higashitsuji, H.2
Masuda, T.3
Liu, Y.4
Itoh, K.5
Fujita, J.6
-
68
-
-
0343484254
-
Regulation of E2F1 activity by acetylation
-
Martinez-Balbas, M.A., Bauer, U.M., Nielsen, S.J., Brehm, A. and Kouzarides, T. (2000) Regulation of E2F1 activity by acetylation. EMBO J. 19, 662-671
-
(2000)
EMBO J.
, vol.19
, pp. 662-671
-
-
Martinez-Balbas, M.A.1
Bauer, U.M.2
Nielsen, S.J.3
Brehm, A.4
Kouzarides, T.5
-
69
-
-
77956604362
-
Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation
-
Trivedi, C.M., Zhu, W., Wang, Q., Jia, C., Kee, H.J., Li, L., Hannenhalli, S. and Epstein, J.A. (2010) Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev. Cell 19, 450-459
-
(2010)
Dev. Cell
, vol.19
, pp. 450-459
-
-
Trivedi, C.M.1
Zhu, W.2
Wang, Q.3
Jia, C.4
Kee, H.J.5
Li, L.6
Hannenhalli, S.7
Epstein, J.A.8
-
70
-
-
77952002655
-
Redundant control of adipogenesis by histone deacetylases and 2
-
Haberland, M., Carrer, M., Mokalled, M.H., Montgomery, R.L. and Olson, E.N. (2010) Redundant control of adipogenesis by histone deacetylases 1 and 2. J. Biol. Chem. 285, 14663-14670
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 14663-14670
-
-
Haberland, M.1
Carrer, M.2
Mokalled, M.H.3
Montgomery, R.L.4
Olson, E.N.5
|